Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,607 recruiting studies in this area right now.
By phase
- Not applicable5,335
- Phase 2607
- Phase 1557
- Phase 3417
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity619
- Ovarian Cancer336
- Pancreatic Cancer289
- Type 2 Diabetes276
- Diabetes192
- Diabetes Mellitus183
- Diabetes Mellitus, Type 2170
- Hypertension138
- Type 1 Diabetes130
- Metabolic Syndrome126
- Obesity & Overweight123
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Colorectal Cancer92
- Pancreas Cancer90
- Endometrial Cancer87
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center41
- Massachusetts General Hospital41
- Eli Lilly and Company40
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland180
- Alabama176
- Arizona170
- Florida166
- Texas158
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania113
Recruiting studies7,607 total
- NCT04282044RecruitingPhase 1
CRX100 drug trial for advanced cancers with or without pembrolizumab
This Phase 1 trial tests CRX100 (a new cancer medicine) alone and with pembrolizumab (an immune checkpoint drug) in people with advanced solid tumors. It’s mainly designed to check safety and side effects, and to see whether tumors respond, potentially helping people whose cancer has come back or stopped responding to standard treatment.
Scottsdale, ArizonaAges 18 years+ - NCT06249308Recruiting
Liquid biopsy test for early ovarian cancer detection
This study is testing a blood test to see if it can catch ovarian cancer early. You may be eligible if you have been recently diagnosed with ovarian cancer and haven't started treatment yet.
Guangzhou, GuangdongAges 40–75 - NCT07858864Recruiting
GLP-1 weight loss drugs and muscle health in obesity
This study looks at how GLP-1 receptor agonist drugs (used for weight loss) affect muscle mass and strength in people with obesity who do not have diabetes. It may help understand if these medications impact muscle health.
Istanbul, KucukcekmeceAges 18 years+ - NCT07866846Recruiting
Ketogenic diet for blood sugar side effects of pasireotide in acromegaly
This study tests whether a low-carbohydrate ketogenic diet can help manage high blood sugar caused by the medication pasireotide, which is used to treat acromegaly. If you are being considered for or already taking pasireotide and your blood sugar is rising, this diet might help you avoid or reduce the need for diabetes medications.
Leiden, South HollandAges 18 years+ - NCT05652283RecruitingPhase 2
Combination treatment before surgery for advanced ovarian cancer
This trial tests two oral medications, pamiparib and surufatinib, given before surgery to shrink advanced ovarian cancer. The goal is to make surgery more successful and potentially improve outcomes for patients who cannot have surgery right away.
Hefei, AnhuiAges 18 years+ - NCT07874321RecruitingPhase 2
Study of MRG003 for advanced thyroid cancer that has progressed on current therapy
This trial tests an investigational drug called MRG003 added to your current treatment for advanced thyroid cancer that has stopped responding. It may help people with specific types of thyroid cancer and certain tumor markers.
Guangzhou, GuangdongAges 18–80 - NCT07173387RecruitingPhase 2
Radiation plus chemo for locally advanced pancreatic cancer
This trial combines focused radiation with a chemotherapy drug combo to help shrink or control locally advanced pancreatic cancer. If it works, this treatment might make the tumor smaller and improve quality of life.
Jinan, ShandongAges 18–75 - NCT06250595Recruiting
European rare blood disorder registry
This study is building a registry of people with rare blood diseases. By joining, you help doctors learn more about these conditions and improve future care.
Barcelona, CataloniaAges Up to 100 years - NCT05988814RecruitingPhase 2
FOLFIRINOX3 for advanced pancreatic cancer
This trial tests a stronger version of FOLFIRINOX chemotherapy for people with pancreatic cancer that cannot be removed by surgery or has spread to other parts of the body. It aims to see if the new dosing schedule works better and is safe.
DijonAges 18 years+ - NCT02973412Recruiting
How sleep timing affects blood sugar in diabetes
This study looks at your daily sleep–wake timing (“chronotype”) and how it may affect blood sugar control in people with diabetes. It may help researchers learn whether sleep patterns could improve glucose levels.
LeicesterAges 18–75 - NCT06254768Recruiting
Continuous glucose monitors for kids with obesity
This study tests if using a continuous glucose monitor (CGM), a small device that tracks blood sugar, can help children and teens with obesity understand their body better and improve their health.
Los Angeles, CaliforniaAges 10–21 - NCT05315752Recruiting
Body fat changes after CPAP-treated sleep apnea improves
This study looks at how bariatric (weight-loss) surgery may change body fat and body shape in people with severe obstructive sleep apnea who use CPAP. It aims to understand what may improve when sleep apnea is better controlled after surgery.
BrusselsAges 18–99 - NCT05391945Recruiting
Thyroid surgery and sleep apnea in people with goiters
This trial studies whether planned thyroidectomy (thyroid surgery) changes obstructive sleep apnea (breathing pauses during sleep) in people who have a goiter. It may help doctors understand whether treating the thyroid affects nighttime breathing.
BrusselsAges 18–90 - NCT06250699Recruiting
Rapid recovery after urologic surgery
This trial tests a program to help patients recover faster after urologic surgery. It focuses on making sure you heal well and get back to your normal life quickly.
Wuhan, HubeiAges 18–70 - NCT04583150Recruiting
Study of fertility and ovarian reserve after weight-loss surgery
This study looks at how ovarian reserve (a fertility-related marker) changes in women after bariatric (weight-loss) surgery versus women with obesity who are not planning surgery. It may help doctors better understand fertility timing and risks around weight-loss treatment.
AngersAges 18–37 - NCT00455104Recruiting
Fabry disease registry for Canadians and eligible adults
This study is a national registry that collects health and medical information from people with Fabry disease. It helps researchers better understand the condition and plan future care and studies.
Calgary, AlbertaAges 5–85 - NCT05599438Recruiting
Fitness and drug use study in recreational athletes
This study follows recreational athletes to understand how past and current anabolic-androgenic steroid (AAS) use relates to fitness changes over time. If you have used these substances in the past (and stopped more than 3 months ago), or you have never used them, you may be able to join.
CopenhagenAges 18 years+ - NCT02526901Recruiting
Pregnancy cohort study for women in Guangzhou
This study follows pregnant women from early pregnancy to learn about pregnancy and child health. You may be asked to share health information so researchers can better understand outcomes for babies born in Guangzhou.
Guangzhou, GuangdongAges Any age - NCT02829684Recruiting
Register for people with Prader-Willi syndrome
This is a patient registry that collects information about people with Prader-Willi syndrome. It may help researchers better understand the condition and plan future studies.
ToulouseAges Any age - NCT07874087Enrolling by invitation
Kidney stones in children: risks and causes
This study looks at children who have had kidney stones or a related condition called nephrocalcinosis. It aims to learn why these happen in children and what risks or causes are involved, which may help improve care.
Milan, MilanoAges birth–18 years - NCT07857460Recruiting
German registry for low parathyroid hormone levels
This study is a registry that collects health information from people with chronic low parathyroid hormone (hypoparathyroidism) or pseudohypoparathyroidism. It aims to better understand these conditions and improve future care. You may join if you are an adult living in Germany.
Augsburg, BavariaAges 18 years+ - NCT07873606Recruiting
Sound wave treatment for advanced pancreatic cancer
This trial tests a new non-invasive treatment that uses sound waves to break up cancer cells in the pancreas. It is for people whose pancreatic cancer cannot be removed by surgery and who are well enough for anesthesia.
Hong KongAges 18 years+ - NCT07392476Recruiting
Glucose monitor for women with polycystic ovary syndrome
This study tests whether a continuous glucose monitor (a small sensor that tracks your blood sugar) can help women with PCOS understand their glucose levels. It may help you learn how your body responds to food and daily activities.
Cleveland, OhioAges 18–45 - NCT06264427Recruiting
Study of metabolism issues in Greenland
This study looks at the genes and physical traits of people in Greenland with type 2 diabetes or severe obesity. It aims to better understand these conditions to improve care.
Nuuk, SermersooqAges 18 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,607 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,814 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.