Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,627 recruiting studies in this area right now.
By phase
- Not applicable5,353
- Phase 2607
- Phase 1557
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity618
- Ovarian Cancer337
- Pancreatic Cancer287
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes131
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Cardiovascular Diseases105
- Overweight105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida166
- Texas158
- Massachusetts151
- New York144
- Colorado115
- Pennsylvania114
Recruiting studies7,627 total
- NCT06888388Recruiting
Safety of nipple-sparing mastectomy for women with high-risk genes
This study looks at the long-term safety of a type of breast surgery (nipple-sparing mastectomy) in women who carry certain inherited gene changes (BRCA1, BRCA2, PALB2, TP53, CDH1, or PTEN) that increase their risk of breast cancer. The goal is to understand how safe this surgery is over time for these women.
New Haven, ConnecticutAges 18–90 - NCT06881641Recruiting
A bedside test for methanol poisoning
This study tests a new bedside tool to quickly diagnose methanol poisoning in people who may have drunk contaminated alcohol or have unexplained high acid levels. Early diagnosis can help start the right treatment faster.
Bogra, BoguraAges 16 years+ - NCT06884358Recruiting
Heart and exercise capacity in Fabry disease
This study looks at how Anderson-Fabry disease affects your heart and ability to exercise. Researchers want to understand this better by testing your heart function and how well you can do physical activity.
Brescia, BresciaAges Any age - NCT06881992RecruitingPhase 3
Testing ersodetug for low blood sugar from neuroendocrine tumors
This study tests a new medicine called ersodetug in people whose neuroendocrine tumors cause dangerously low blood sugar that standard treatments can't control. If you need IV sugar or nutrition for at least a week, this trial may offer a new option to help manage your blood sugar.
Chicago, IllinoisAges 18 years+ - NCT00097292Recruiting
Preventing Type 1 Diabetes in At-Risk People
This study looks for people at high risk of developing type 1 diabetes (based on family history or blood markers) and follows them over time to understand disease development. The goal is to eventually prevent or delay type 1 diabetes in people who don't have it yet.
Orange, CaliforniaAges 2–45 - NCT06767722Recruiting
Lifestyle program for high blood sugar in early pregnancy
This trial tests if a lifestyle program (diet and activity changes) can help pregnant women who have slightly high blood sugar in early pregnancy. It aims to improve glucose levels and reduce complications for both mother and baby.
Guangzhou, GuangdongAges 18–55 - NCT05542056Recruiting
Test urine markers to predict low sodium from water pills
This study looks for a signal in your urine that could help predict who will develop low blood sodium (hyponatremia) after starting a thiazide-type “water pill.” It may help doctors spot higher-risk people early and adjust care sooner.
MóstolesAges 18 years+ - NCT06585072Recruiting
Pancreatic cancer and diabetes risk after surgery
This trial studies how pancreatic cancer affects blood sugar and the risk of developing diabetes after surgery. Patients who have their pancreas removed will provide blood and tissue samples to help understand this link.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06876090Recruiting
Sarcopenia study in women with gestational diabetes
This trial looks at muscle health (sarcopenia) in women who had gestational diabetes during pregnancy. It aims to understand how gestational diabetes might affect muscle mass and function.
ViennaAges 35 years+ - NCT06879080Recruiting
Maternal iron levels and child health
This trial looks at how a mother’s iron levels during pregnancy might affect her child’s health. It aims to learn more about the link, which could help improve care for both.
Tampere, PirkanmaaAges Any age - NCT06879652Recruiting
Does dairy affect weight and health in teens and seniors?
This study looks at how eating more dairy might affect body weight, body composition, and health in adolescents and older adults who have some extra weight and borderline high blood sugar. It will likely compare a higher dairy diet to a usual diet.
Toronto, OntarioAges 14–80 - NCT06869941Recruiting
How gut health and fat tissue are linked in the brain
This study looks at how the bacteria in your gut might affect your fat tissue and brain. You may be able to join if you are scheduled to have surgery to remove fat tissue and are willing to sign a consent form.
Girona, GironaAges 20 years+ - NCT06871293Recruiting
Long Covid recovery: rehab with coaching
This study tests a program of rehab exercises and memory/thinking activities, along with coaching messages, to help people with Long Covid feel better and function in daily life. You may qualify if you had Covid, have high blood pressure or diabetes, and still have symptoms like fatigue or trouble thinking for at least 4 weeks.
Bogotá, Bogotá DCAges 18–80 - NCT06868862Recruiting
Exercise and fat loss in young women with overweight or obesity
This study compares two types of exercise (short bursts of intense activity vs. moderate continuous activity) to see which is better for fat loss in young women who have overweight or obesity. The exercises have the same total energy used, so the results can show which type might be more helpful for weight management.
São Paulo, São PauloAges 20–45 - NCT06875739Enrolling by invitation
Saliva test for early diagnosis of brain diseases
This study tests whether a saliva sample can help tell the difference between brain diseases like Alzheimer's, Parkinson's, and related conditions. By using a special laser technique, researchers hope to find a quick, non-invasive way to make an earlier and more accurate diagnosis.
CagliariAges 60–85 - NCT06869057Recruiting
Improving diabetes care after hospital discharge
This study tests a redesigned discharge process to help people with type 2 diabetes manage their health after leaving the hospital. It focuses on patients who also have unmet social needs, like food or housing issues.
Worcester, MassachusettsAges 18 years+ - NCT06876675Enrolling by invitation
Lorlatinib and high cholesterol in ALK+ lung cancer
This study looks at how the drug Lorlatinib affects cholesterol levels in people with ALK-positive non-small cell lung cancer. It aims to understand and manage these side effects better.
BeijingAges 18–80 - NCT06869291Enrolling by invitation
Minimally invasive treatment for eyelid cholesterol deposits
This trial tests a new minimally invasive procedure using tiny tunnels and a heparin injection to treat xanthelasma (cholesterol deposits under the skin of the eyelids). It may help reduce the appearance of these deposits with less scarring than traditional methods.
Fuzhou, FujianAges 18–65 - NCT06878872Recruiting
Healthier lifestyles for teens with type 1 diabetes
This study helps teens with type 1 diabetes and their parents make healthier lifestyle changes. If your teen is above a certain weight range and has had diabetes for at least 6 months, they may be able to join.
Providence, Rhode IslandAges 13–18 - NCT06869850Recruiting
Special milk-enriched food for children with severe malnutrition
This study tests a special food to help children with severe malnutrition recover. The food is a peanut-based paste with added milk fat globule membrane, which may help kids gain weight and get stronger.
Bandajuma, PujehunAges 6 months–4.9 years - NCT06870396Enrolling by invitation
National study of adrenal tumors
This study is collecting information from people with certain adrenal gland tumors (pheochromocytoma, paraganglioma, or adrenocortical tumor). It aims to learn more about these conditions, which may help improve future care. Both living and deceased patients can be included.
Cambridge, UKAges 18 years+ - NCT06877143Recruiting
High-calorie PEG nutrition for ALS energy needs
This trial tests whether a special high-calorie formula given through a PEG tube can help people with ALS maintain energy balance and potentially slow disease progression. It is for adults with ALS who are already using a PEG tube for nutrition.
Ulm, Baden-WurttembergAges 18 years+ - NCT06877923Recruiting
Elemental 028 extra nutritional support study
This study is testing a special liquid food called Elemental 028 Extra for people who need at least 30% of their nutrition from an elemental formula. It aims to see how well it works and how people tolerate it.
TrowbridgeAges 3 years+ - NCT06868849RecruitingPhase 1/Phase 2
Study of JMT203 for Cancer-Related Weight Loss
This trial tests a new drug called JMT203 for people with cancer-related weight loss (cachexia). It aims to see if the drug can help prevent or reverse weight loss in patients with certain solid tumors who are also receiving or have recently completed anti-cancer therapy.
ZhejiangAges 18 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,627 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,981 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.