Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,607 recruiting studies in this area right now.
By phase
- Not applicable5,333
- Phase 2607
- Phase 1559
- Phase 3418
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 384
Top conditions
- Obesity620
- Ovarian Cancer335
- Pancreatic Cancer287
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus183
- Diabetes Mellitus, Type 2171
- Hypertension138
- Type 1 Diabetes130
- Metabolic Syndrome126
- Obesity & Overweight124
- Breast Cancer110
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Colorectal Cancer90
- Pancreas Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- Eli Lilly and Company41
- M.D. Anderson Cancer Center41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California520
- Maryland180
- Alabama176
- Arizona171
- Florida166
- Texas158
- Massachusetts150
- New York142
- Colorado115
- Pennsylvania113
Recruiting studies7,607 total
- NCT07603466Enrolling by invitationPhase 4
Two drugs combined to treat Cushing's disease
This trial tests whether taking two medications together—osilodrostat and cabergoline—can help control Cushing's disease by lowering excess cortisol levels. Cushing's disease is caused by a pituitary tumor that makes too much of a hormone called ACTH, which drives cortisol overproduction.
BasraAges 18–70 - NCT07595666Enrolling by invitation
New PET scanner versus standard PET for head and neck imaging
This study compares a newer PET/CT scanner (called NeuroEXPLORER) with standard PET/CT scanners for imaging the head and neck region. The goal is to see if the new scanner provides better or clearer images to help diagnose conditions.
Leuven, Vlaams-BrabantAges 4 weeks+ - NCT07600580RecruitingPhase 4
Nerve blocks for thyroid surgery to reduce stress response
This study tests whether a special numbing technique (nerve block) given during thyroid removal surgery can reduce your body's stress response and help you recover better. Researchers will measure how well this approach works compared to standard care.
Zagreb, City of ZagrebAges 18 years+ - NCT07597850RecruitingPhase 2
TCM formula versus HMB supplement for muscle strength in older adults
This study compares a traditional Chinese medicine formula with HMB (a muscle-building supplement) to see which helps preserve muscle strength and bone health in adults aged 65 and older who are starting to show signs of frailty. Both treatments aim to help you stay stronger and more active as you age.
TaipeiAges 65 years+ - NCT07599306Recruiting
Telehealth Rehabilitation for Heart Patients After ICU Recovery
This study tests whether supervised remote rehabilitation exercises can help people recover better after a long ICU stay. Many patients struggle with weakness, memory problems, or mood changes after intensive care—this trial aims to improve those symptoms through video-guided therapy.
Milan, MilanoAges 30–75 - NCT07595718Recruiting
Using health data and AI to predict major diseases
This study uses your health information and artificial intelligence to help predict the onset of major diseases. By joining, you could help improve early detection and prevention for conditions like diabetes, heart disease, and cancer.
Seoul, Seoul Special CityAges 30–65 - NCT07600411Recruiting
Weight-loss surgery and mood: comparing two surgical approaches
This study follows patients undergoing one of two common weight-loss surgeries (sleeve gastrectomy or gastric bypass) to see how each affects binge eating, depression, and anxiety. Researchers want to understand which surgery may help improve both weight and mental health outcomes.
Cairo, Al-Manial CairoAges 18–60 - NCT07595835RecruitingPhase 1/Phase 2
Radioactive particles injected into pancreatic tumors
This trial tests a new treatment where doctors use imaging to guide radioactive particles directly into locally advanced pancreatic cancer tumors that haven't spread. The goal is to shrink or control the cancer with radiation delivered right to the tumor.
Amsterdam, North HollandAges 18 years+ - NCT07598773Enrolling by invitation
Continuous glucose monitoring study for prediabetes and type 2 diabetes
This study asks you to wear a glucose monitor and smart ring for several months to help researchers understand how blood sugar changes throughout the day in people with prediabetes or type 2 diabetes. The goal is to learn how lifestyle and medications affect blood sugar control.
San Francisco, CaliforniaAges 18 years+ - NCT07599072Recruiting
Blood Sugar Monitoring Study for Prediabetes
This study tracks how blood sugar levels change in people with prediabetes (higher-than-normal blood sugar but not yet diabetes). Researchers will use a small sensor to monitor your blood sugar and help understand what affects it, which could help prevent or delay type 2 diabetes.
KyivAges 18 years+ - NCT07600268RecruitingPhase 2
Radiation plus maintenance drugs for advanced pancreatic cancer
This trial tests whether adding a focused radiation treatment (SBRT) to ongoing chemotherapy drugs works better than the drugs alone for pancreatic cancer that has stabilized or shrunk after initial treatment. The goal is to see if this combination approach helps patients live longer.
Jinan, ShandongAges 18–70 - NCT07595172RecruitingPhase 1/Phase 2
New drug combination for advanced pancreatic cancer
This study tests whether combining three treatments—NALIRIFOX (chemotherapy), Adebrelimab (an immune-boosting antibody), and PULSAR (radiation)—can help people with advanced pancreatic cancer that hasn't been treated before. The goal is to see if this combination works better than standard care.
Chengdu, SichuanAges 18–75 - NCT01224886Recruiting
Study of age-related insulin resistance and exercise
This study looks at how age affects the way your body uses insulin (a hormone that helps move sugar into cells), and how lifestyle or exercise may change that. It may help you understand insulin resistance and whether changes in activity could improve blood sugar control.
BernAges 60–80 - NCT03811470Recruiting
Diabetes registry study for adults
This study creates a diabetes “registry,” which is a large record of people with diabetes. It helps researchers understand diabetes patterns and how metabolic health changes over time, which may improve future care.
Multiple LocationsAges 18 years+ - NCT03900286Recruiting
Testing a low-calorie diet for partial fat loss diabetes
This trial studies whether a low-calorie (low energy) diet can improve diabetes control in adults with familial partial lipodystrophy. It likely helps by changing how your body handles blood sugar and fat use, but you must meet specific safety and eligibility checks.
CambridgeAges 18–99 - NCT05231876Recruiting
French Wilson disease registry
This study keeps a registry (a confidential list) of people with Wilson disease. It helps researchers learn more about the disease and improve future care, without requiring specific treatment changes.
Paris, Île-de-France RegionAges birth–99 years - NCT03911297Recruiting
DAISy-PCOS study of hormone and metabolism in suspected PCOS
This study looks at hormone levels and metabolism in people who may have polycystic ovary syndrome (PCOS). It aims to better understand why PCOS happens, which could help improve future diagnosis and treatment.
Birmingham, West MidlandsAges 18–70 - NCT06717581Recruiting
Drug interaction study for older people with HIV
This study looks at how other medicines you take for conditions like high blood pressure, diabetes, or cholesterol might interact with your HIV medication (Biktarvy) if you are 60 or older. The goal is to learn how to better manage your overall health.
BolognaAges 18 years+ - NCT05304442RecruitingPhase 3
IV iron for anemia from heavy uterine bleeding
This trial studies whether giving iron through a vein (IV) helps improve anemia caused by heavy uterine bleeding. You may join if you were treated in the emergency department, can go home, and can return for follow-up checks in the next several weeks.
Houston, TexasAges 18–65 - NCT05740514Recruiting
Exercise program study for adults with type 1 diabetes
This study looks at how an exercise program affects “healthy outcomes” in people with type 1 diabetes. You might be invited if you are the right age, generally less active, and have a safe health profile for exercising.
Hamilton, OntarioAges 18–65 - NCT06717893Recruiting
Type 1 diabetes study in children and teens
This study looks at the health records of children and teens newly diagnosed with type 1 diabetes to understand their insulin needs at the start and over the first year. It may help doctors better predict and manage insulin doses for future patients.
BolognaAges Up to 14 years - NCT06095492Recruiting
Comparing diabetes drugs after kidney transplant
This trial tests two diabetes medications, empagliflozin and linagliptin, to see which one works better for controlling blood sugar, protecting kidney function, and improving body composition in people who have had a kidney transplant and have diabetes.
Gurgaon, HaryanaAges 30 years+ - NCT06414668Recruiting
Energyco study: testing active travel to school
This study looks at how biking to school affects students' energy levels and health. Your child's school may be eligible if it has bike parking, no school bus, and enough students interested.
GranadaAges 12–17 - NCT06482086RecruitingPhase 2
Using tumor models to guide drug choice for advanced thyroid cancer
This trial tests whether growing your tumor cells in a lab (as organoids) can help doctors pick the best drugs for advanced thyroid cancer that is hard to remove surgically. It's for people with different thyroid cancer types who have tumors growing outside the thyroid or into nearby areas.
Chengdu, SichuanAges 18 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,607 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,855 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.