Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,230 recruiting studies in this area right now.
By phase
- Not applicable3,147
- Phase 21,063
- Phase 1819
- Phase 1/Phase 2442
- Phase 3425
- Phase 4238
- Phase 2/Phase 396
Top conditions
- Multiple Sclerosis343
- Multiple Myeloma332
- Asthma194
- Lymphoma182
- Rheumatoid Arthritis140
- Type 1 Diabetes133
- Atopic Dermatitis129
- Systemic Lupus Erythematosus125
- Acute Lymphoblastic Leukemia122
- HIV Infections116
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 169
- Hodgkin Lymphoma67
- Rheumatoid Arthritis (RA)66
- Leukemia64
- Type 1 Diabetes Mellitus63
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)90
- National Cancer Institute (NCI)73
- Assistance Publique - Hôpitaux de Paris70
- M.D. Anderson Cancer Center63
- Novartis Pharmaceuticals60
- AstraZeneca57
- City of Hope Medical Center47
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center44
Where studies are running
- California491
- Maryland195
- Alabama175
- Florida144
- Arizona142
- New York123
- Massachusetts119
- Texas118
- Illinois81
- Colorado77
Recruiting studies6,230 total
- NCT06935162RecruitingPhase 2
Teclistamab for previously treated AL amyloidosis
This trial tests a new drug called teclistamab for people with AL amyloidosis whose disease has not responded well to previous treatments. It aims to see if the drug can help control the disease.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06935890RecruitingPhase 4
Long-term effectiveness of jack jumper ant venom therapy
This study checks how well venom immunotherapy for jack jumper ant allergy works years after treatment ends. If you finished 3–5 years of treatment and stopped 1.5 to 5 years ago, you may be able to help.
Adelaide, South AustraliaAges 18 years+ - NCT06936280Recruiting
Type 1 diabetes and diabetes distress study
This trial tests a program for young adults with type 1 diabetes who feel stressed or overwhelmed by their diabetes. The goal is to see if the program can help reduce diabetes distress and improve well-being.
EsbjergAges 18–35 - NCT06937723Recruiting
App-based monitoring for spasticity in multiple sclerosis
This trial tests if a smartphone app can help monitor spasticity (muscle tightness or stiffness) in people with multiple sclerosis. If you have MS and spasticity that needs treatment, using your own smartphone might help track your health.
Düsseldorf, North Rhine-WestphaliaAges 18 years+ - NCT06938009Recruiting
Dutch registry of child cardiac arrest
This trial is a registry study that records information about children under 18 who have had a cardiac arrest in the Netherlands. It aims to collect data to better understand and improve care for children in this situation.
Nijmegen, GelderlandAges 1 day–18 years - NCT06939166RecruitingEarly Phase 1
Immune cell therapy for relapsed neurological autoimmune diseases
This trial tests a new type of immune cell therapy (CAR T-cells) that targets CD19 and BCMA proteins on B cells. It is for people with certain neurological autoimmune diseases that have come back or not responded to standard treatments. The goal is to see if this therapy can help control the disease.
TianjinAges 18 years+ - NCT06939660Recruiting
Brain-spinal cord stimulation for walking after spinal cord injury
This trial tests if combining brain-computer interface technology with spinal cord stimulation can help improve walking in people with chronic spinal cord injury. It aims to see if this approach works when standard rehab has stopped helping.
Beijing, Beijing MunicipalityAges 14–65 - NCT06940323Recruiting
Pregnancy study for women with chronic conditions
This study tracks pregnant women with certain chronic health conditions (like multiple sclerosis, lupus, or rheumatoid arthritis) and healthy pregnant women as a comparison group. It aims to understand how these conditions and their treatments affect pregnancy, the baby, and breast milk.
San Francisco, CaliforniaAges 18–64 - NCT06940661RecruitingPhase 2
Obinutuzumab for relapsing vasculitis
This trial tests a drug called obinutuzumab to see if it can help people whose vasculitis (inflammation of blood vessels) has come back after previous treatment. It is designed for people with a specific type of vasculitis that affects small blood vessels and is linked to PR3-ANCA antibodies.
ParisAges 18 years+ - NCT06940908Recruiting
Living with Guillain-Barré syndrome as a child
This study interviews children who had Guillain-Barré syndrome (GBS) to understand their experiences after recovery. It may help doctors better support young patients with GBS.
Montpellier, OccitanieAges 10–18 - NCT06940960Recruiting
JY231 cell therapy for relapsed B-cell lymphoma or leukemia
This trial tests a new cell therapy (JY231) for people whose B-cell lymphoma or leukemia (B-ALL) has returned or not responded to earlier treatments. The therapy uses your own T cells, modified to target the CD19 marker on cancer cells.
Guangzhou, GuangdongAges 12–75 - NCT06941129RecruitingPhase 1
CAR T-cell therapy for resistant autoimmune diseases
This trial tests a new type of immune therapy called CAR T-cells that target two markers on your B cells (CD19 and BCMA). It is for people with certain autoimmune diseases that have not improved or have come back after standard treatments. The goal is to see if this therapy can help control the disease.
TianjinAges 18 years+ - NCT06941194Recruiting
Preventing wound problems after sarcoma surgery with a special bandage
This trial tests a special negative pressure bandage used after surgery to prevent wound complications in people with high-grade soft tissue sarcoma of the limbs who have had radiation therapy before their operation.
Padova, Italy/PadovaAges 18–99 - NCT06941584Recruiting
AIRE gene's role in autoimmune nerve diseases
This study looks at how the AIRE gene affects people with autoimmune nerve diseases like NMOSD, myasthenia gravis, and autoimmune encephalitis when they also have other autoimmune conditions. It may help researchers understand why some people get multiple autoimmune problems.
RomaAges 18 years+ - NCT06941675Recruiting
Automated insulin system for LADA diabetes
This trial tests a hybrid closed-loop insulin pump system for people with LADA (a slow-progressing form of autoimmune diabetes). It aims to see if the system can improve blood sugar control and reduce hypoglycemia.
Taiyuan, ShanxiAges 18–70 - NCT06943534RecruitingPhase 2
Omalizumab for severe food allergies: weight-based dosing study
This trial tests if omalizumab (a drug that blocks allergy reactions) can help people with multiple food allergies. You might qualify if you have severe allergies to at least two foods like peanut, tree nuts, egg, or milk.
Boston, MassachusettsAges 1–55 - NCT06943937RecruitingPhase 1
Cell therapy for hard-to-treat lupus
This trial tests a new type of cell therapy (YTS109 cells) for people with severe lupus that hasn't been controlled by standard treatments. The goal is to see if these cells can help calm the immune system and improve lupus symptoms.
Beijing, Beijing MunicipalityAges 18–65 - NCT06945406RecruitingPhase 1
Study of an investigational drug for diabetes
This trial tests a new medicine, LY4057996, in people with type 1 or type 2 diabetes and in healthy volunteers. It aims to see if the drug is safe and how it works in the body.
NeussAges 18 years+ - NCT06946199RecruitingPhase 1
Study of Cizutamig for Hard-to-Treat Rheumatoid Arthritis
This trial tests an experimental drug called cizutamig for people with rheumatoid arthritis that hasn't responded to other treatments. It aims to see if a new approach can help control the disease in patients who still have active inflammation despite trying other advanced therapies.
Wuhan, HubeiAges 18–75 - NCT06946641RecruitingPhase 1
Testing QLS12010 safety in healthy adults and people with eczema
This trial tests a new drug, QLS12010, to see if it is safe and how it works in healthy volunteers and in people with moderate to severe atopic dermatitis (eczema). It may offer a new treatment option for those whose eczema has not improved with topical creams.
BeijingAges 18–75 - NCT06947044Recruiting
Blood markers for bleeding in leukemia patients
This study looks at markers in the blood to understand why low red blood cell counts (anemia) can cause bleeding problems in people with certain leukemias. It may help find better ways to treat or prevent bleeding during early chemotherapy.
Hamilton, OntarioAges 18 years+ - NCT06947473RecruitingPhase 1/Phase 2
CAR T-cell therapy for lupus, sclerosis, and Sjogren's
This trial tests a new type of immune cell therapy (CAR T-cells from umbilical cord blood) for people with certain autoimmune diseases that haven't responded to standard treatments. It aims to see if targeting two proteins (CD19 and BCMA) can help calm the overactive immune system.
Beijing, Beijing MunicipalityAges 6–65 - NCT06947746Recruiting
Studying stem cells for rheumatoid arthritis knee pain
This trial tests if stem cells can improve pain and swelling in the knee for people with rheumatoid arthritis that hasn't responded well to standard treatments. It's for those who still have significant knee symptoms despite taking medications.
ShanghaiAges 18–65 - NCT06947967RecruitingPhase 3
Tucidinostat plus CHOP for newly diagnosed PTCL-TFH lymphoma
This trial tests a new drug (tucidinostat) added to standard chemotherapy (CHOP) for people newly diagnosed with a specific type of lymphoma called PTCL-TFH. It aims to see if the combination works better than standard treatment alone.
Guangzhou, GuangdongAges 18–80
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,230 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,763 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.