Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,230 recruiting studies in this area right now.
By phase
- Not applicable3,146
- Phase 21,063
- Phase 1820
- Phase 1/Phase 2442
- Phase 3425
- Phase 4238
- Phase 2/Phase 396
Top conditions
- Multiple Sclerosis343
- Multiple Myeloma332
- Asthma194
- Lymphoma183
- Rheumatoid Arthritis140
- Type 1 Diabetes134
- Atopic Dermatitis130
- Systemic Lupus Erythematosus125
- Acute Lymphoblastic Leukemia122
- HIV Infections113
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 169
- Hodgkin Lymphoma67
- Rheumatoid Arthritis (RA)66
- Leukemia64
- Type 1 Diabetes Mellitus63
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)90
- National Cancer Institute (NCI)73
- Assistance Publique - Hôpitaux de Paris70
- M.D. Anderson Cancer Center63
- Novartis Pharmaceuticals60
- AstraZeneca57
- City of Hope Medical Center47
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center44
Where studies are running
- California494
- Maryland195
- Alabama176
- Florida145
- Arizona141
- New York122
- Massachusetts119
- Texas118
- Illinois81
- Colorado76
Recruiting studies6,230 total
- NCT07611838Recruiting
Predicting ABPA Recurrence Using Blood and Immune Markers
This study helps doctors predict whether allergic bronchopulmonary aspergillosis (ABPA)—a serious lung condition caused by fungal allergy—will come back after treatment. Researchers will analyze blood samples and immune system markers to identify patients at higher risk of relapse, which could improve how doctors monitor and treat you.
Jinan, ShandongAges 18–80 - NCT07612319Recruiting
Romiplostim injection for treatment-resistant ITP
This trial tests romiplostim, a weekly injection, for patients with ITP (a blood disorder where the body destroys its own platelets) who did not respond to or could not tolerate oral medications. It aims to help raise platelet counts and reduce bleeding risk.
Suzhou, JiangsuAges 18 years+ - NCT07614321RecruitingPhase 4
Silodosin for Bladder Symptoms in Women With MS
This study tests whether silodosin, a medication that relaxes bladder muscles, can help women with multiple sclerosis who have bothersome urinary symptoms. The goal is to see if it can reduce urgency, frequency, and other lower urinary tract problems.
Morristown, New JerseyAges 18 years+ - NCT07614633Recruiting
Understanding Eosinophilic Esophagitis Over Time
This study follows patients with eosinophilic esophagitis (a condition where too many white blood cells called eosinophils build up in the food tube) to understand how the disease changes over time and what happens with different treatments. By tracking your symptoms and test results, doctors hope to learn how to better manage this condition.
Pavia, PaviaAges 5 years+ - NCT07615725Recruiting
Dry Needling for Lower Leg Pain in Multiple Sclerosis
This study tests whether dry needling—a technique using thin needles to treat muscle pain—can help reduce lower leg pain in people with multiple sclerosis. Researchers want to see if this treatment can safely improve pain and function.
Tampa, FloridaAges 18–80 - NCT07616700RecruitingPhase 2
Long-term safety study of HSK39297 for IgA kidney disease
This study continues treatment with an experimental medicine called HSK39297 for people with IgA nephropathy, a condition where the immune system damages the kidneys. The trial will track how safe and effective the medicine is over time in people who already completed an earlier study.
BeijingAges Any age - NCT07617740RecruitingEarly Phase 1
IASO207 cell therapy for treatment-resistant lupus
This early-stage trial tests IASO207, a new cell therapy designed to help people with severe lupus that hasn't improved with standard medications. The therapy works by modifying immune cells to reduce lupus activity.
BeijingAges 18–75 - NCT07620691Recruiting
N95 Masks for Lung Health While Golfing During Wildfire Season
This study tests whether wearing N95 masks while golfing during wildfire season protects your lungs from smoke. If you golf regularly and live in an area with wildfire smoke, this trial may help you understand how to stay safe while enjoying the sport.
Saskatoon, SK - SaskatchewanAges 18 years+ - NCT07621445Recruiting
Understanding Genetic Risk in Recently Diagnosed Diabetes
This study looks at genetic factors in people recently diagnosed with diabetes to understand what might predict who needs insulin treatment. Researchers will analyze blood samples and medical information to see if genetic testing could help doctors predict your treatment path.
Changsha, HunanAges 14–50 - NCT07623850RecruitingPhase 1
Early Study of JLM019 Injection for Advanced Cancers
This is an early-stage trial testing a new cancer treatment called JLM019 in patients with advanced solid tumors or lymphomas that haven't responded to other treatments. The study aims to find the right dose and see how well the drug works and how patients tolerate it.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07624838Recruiting
Brentuximab vedotin plus chemotherapy for CD30+ T-cell lymphoma
This study looks at how well a combination drug treatment (brentuximab vedotin plus chemotherapy) works for patients with rare T-cell lymphomas in real-world clinical practice in Spain. It focuses on patients receiving this as their first treatment.
A Coruña, A CoruñaAges 18 years+ - NCT07626476RecruitingEarly Phase 1
CAR-T Cell Therapy for Advanced Light Chain Amyloidosis
This early-stage trial tests a new cell therapy using your own immune cells (genetically modified to target amyloid-producing cells) to treat light chain amyloidosis that hasn't responded to standard treatments. The goal is to help patients whose disease has come back or stopped responding to previous therapies.
Beijing, Fengtai DistrictAges 18 years+ - NCT07627542Recruiting
Smartphone use and neck posture in arthritis patients
This study looks at how much time people with rheumatoid arthritis or ankylosing spondylitis spend on smartphones and how it affects their neck posture, balance, and disability. Understanding this connection may help doctors give better advice about phone use and neck health.
Konya, MeramAges 18–65 - NCT07628634RecruitingEarly Phase 1
Testing a Low-Methionine Diet in Solid Tumor Patients
This early-stage study explores whether eating a diet low in methionine (a natural amino acid found in protein) might help people with advanced solid tumors. Researchers will track how this dietary change affects blood levels and may improve treatment outcomes alongside standard cancer care.
Orange, CaliforniaAges 18 years+ - NCT07628738RecruitingPhase 2
Lower-dose radiation for early-stage NK/T-cell lymphoma after chemotherapy
This study tests whether patients with a specific type of blood cancer (NK/T-cell lymphoma) in the nose or sinuses who have responded well to chemotherapy can be safely treated with reduced radiation doses instead of standard high-dose radiation. The goal is to reduce side effects while maintaining effective treatment.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07629596RecruitingEarly Phase 1
mRNA CAR-T therapy for severe lupus or autoimmune anemia
This early-stage trial tests a new mRNA-based therapy called Arnovie101 that trains your immune cells to fight lupus (SLE) or autoimmune hemolytic anemia (AIHA) that haven't improved with standard treatments. The therapy may help reduce disease activity and symptoms.
Beijing, Beijing MunicipalityAges 18–60 - NCT07629778RecruitingPhase 1/Phase 2
HL-300 Ointment for Mild-to-Moderate Atopic Dermatitis
This study tests a new ointment (HL-300) designed to treat mild-to-moderate atopic dermatitis (a chronic skin condition causing itching and inflammation). You would apply it to affected skin areas to see if it safely reduces symptoms.
Hangzhou, ZhejiangAges 18–75 - NCT07630311Recruiting
Balance and walking study in multiple sclerosis
This study looks at how multiple sclerosis affects balance, walking patterns, and movement. Researchers will use motion analysis to understand changes, which could help improve treatments.
IoanninaAges 18 years+ - NCT07632014Recruiting
Cancer Care Study for Young People Ages 0–21
This research study follows young people (babies through age 21) who have been diagnosed with cancer and are currently receiving treatment or in follow-up care. The study aims to better understand their care experiences and outcomes.
YerevanAges birth–21 years - NCT07632352Recruiting
Acupuncture for Sudden Asthma Attacks
This trial tests whether acupuncture can help relieve symptoms during sudden, severe asthma attacks. Researchers want to see if this traditional treatment method can reduce breathing problems and improve recovery.
Zhengzhou, HenanAges 18 years+ - NCT07632846RecruitingPhase 2
Roflumilast as add-on treatment for active rheumatoid arthritis
This study tests whether adding roflumilast, a new medication, to your current rheumatoid arthritis treatment can help reduce joint inflammation and improve your symptoms. You would take it alongside methotrexate, a common RA medication you may already be using.
Al MansurahAges 18–60 - NCT07632872RecruitingPhase 2
Adding Desloratadine to Rheumatoid Arthritis Treatment
This study tests whether desloratadine, an allergy medication, can help reduce rheumatoid arthritis symptoms when added to your current treatments. Researchers want to see if it reduces joint swelling and pain alongside your existing therapy.
Al MansurahAges 18–60 - NCT07634770RecruitingPhase 1
Oral insulin study compared to injected insulin
This early-stage study tests whether a new oral (swallowed) form of insulin called SCD0503 works as well as regular injected insulin in men with type 1 diabetes. Researchers will also check how food affects how your body absorbs the oral insulin.
Neuss, North Rhine-WestphaliaAges 18–64 - NCT07635693Recruiting
ATLG Levels During Stem Cell Transplant for Multiple Sclerosis
This study measures how a specific immune-suppressing medication (ATLG) works in patients with multiple sclerosis who are undergoing autologous stem cell transplantation—a procedure where your own blood stem cells are removed, treated, and returned to help reset your immune system.
Milan, ItalyAges 18 years+
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,230 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,786 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.