Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,069 recruiting studies in this area right now.
By phase
- Not applicable3,003
- Phase 21,060
- Phase 1795
- Phase 1/Phase 2443
- Phase 3437
- Phase 4232
- Phase 2/Phase 399
Top conditions
- Multiple Sclerosis331
- Multiple Myeloma329
- Asthma194
- Lymphoma179
- Type 1 Diabetes132
- Rheumatoid Arthritis131
- Atopic Dermatitis121
- Systemic Lupus Erythematosus120
- Acute Lymphoblastic Leukemia118
- HIV Infections105
- Chronic Lymphocytic Leukemia96
- Autoimmune Diseases79
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Hodgkin Lymphoma64
- Diabetes Mellitus, Type 163
- Leukemia63
- Mantle Cell Lymphoma63
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca63
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- City of Hope Medical Center50
- Mayo Clinic50
- Memorial Sloan Kettering Cancer Center44
Where studies are running
- California498
- Maryland198
- Alabama178
- Florida152
- Arizona150
- Massachusetts116
- New York115
- Texas112
- Illinois86
- Colorado81
Recruiting studies6,069 total
- NCT01441089Recruiting
Donate blood for genetic testing in an NIH research study
This study collects blood from people already in an NIH (National Institutes of Health) clinical research program to run genetic tests. It may help researchers understand cancer and related inherited conditions by studying DNA changes.
Bethesda, MarylandAges 3 years+ - NCT01386437Recruiting
Study immune problems and fungal infections
This study looks at how immune system problems relate to fungal infections, using medical records and lab tests on blood and tissue. It may help researchers understand the cause of these infections—especially for people with inherited immune conditions—and improve future care.
Bethesda, MarylandAges 1 day–99 years - NCT01520844Recruiting
HIV cohort study comparing people on and off treatment
This study follows adults with HIV over time to compare different groups based on how stable their virus levels are. It may help researchers understand who can safely interrupt treatment and who should stay on it, and how immune health changes.
Le Kremlin-BicêtreAges 18–85 - NCT02000687Recruiting
Long-term follow-up after islet transplant graft failure
This study follows people over the long term after their islet transplant fully stops working. It aims to learn what happens after complete graft loss and monitor health outcomes over time.
Miami, FloridaAges 18–75 - NCT01890486Recruiting
Collecting information from people having a stem cell transplant
This study aims to collect, store, and share data from patients who are receiving standard intensive treatment and a stem cell transplant from either their own cells or a donor. It may help improve how future patients are treated by building a reliable record of outcomes and care patterns.
Winston-Salem, North CarolinaAges 18–120 - NCT01371630RecruitingPhase 1/Phase 2
Inotuzumab plus chemotherapy for certain types of childhood-like leukemia
This early-phase trial studies how well a targeted drug (inotuzumab ozogamicin) combined with chemotherapy treats acute lymphoblastic leukemia (ALL). It may help people with newly diagnosed ALL who may not tolerate standard intensive chemotherapy, especially older adults.
Houston, TexasAges 18 years+ - NCT01656603RecruitingPhase 2
Safety study of unlicensed cord blood for unrelated transplants
This trial studies whether unlicensed (not FDA-approved) cord blood units made by a specific program are safe to use for unrelated transplants. It may help doctors confirm safe ways to use these units for people who need a transplant for blood-forming system disorders.
Birmingham, AlabamaAges Any age - NCT02134574Recruiting
Study of blood cancers in adults in southern France
This study follows adults who are being checked for a possible blood cancer, or who were recently diagnosed with a blood cancer within the last 6 months. It may help doctors understand the condition better and improve how early workups and care are organized.
MontpellierAges 18 years+ - NCT01484236Recruiting
Lymphangioleiomyomatosis patient registry in France
This trial is a national registry that collects information about people with lymphangioleiomyomatosis to better understand the condition and care over time. It may help by contributing real-world data from patients with sporadic disease or related tuberous sclerosis.
LyonAges 18 years+ - NCT01853631RecruitingPhase 1
CAR T-cell therapy for CD19-positive B-cell blood cancers
This Phase 1 study tests a personalized form of immune therapy called CAR T cells that are designed to recognize CD19, a marker on certain B-cell cancers. It may help people with difficult-to-treat (recurrent or relapsed) B-cell lymphoma or leukemia (ALL/CLL).
Houston, TexasAges Up to 75 years - NCT01477359Recruiting
Sarcoidosis and the heart: a long-term study
This study follows people with sarcoidosis that may or may not be affecting the heart. It uses special scans (PET and MRI) to look for heart involvement and track how the disease changes over time.
Calgary, AlbertaAges 18–99 - NCT01779115Enrolling by invitation
Diabetes registry for people with diagnosed high blood sugar
This is a research registry that collects information from people who have diabetes (high blood sugar on tests or based on diabetes treatment). It may help researchers understand diabetes patterns in a real-world healthcare system.
Tel AvivAges Any age - NCT01536522Enrolling by invitationEarly Phase 1
Study of asthma inflammation and diet effects
This early-phase study looks at how asthma-related inflammation works and whether a diet-related approach could help. It may be most relevant if you have confirmed asthma and can follow the study’s diet requirements.
Cleveland, OhioAges 18–75 - NCT01949129RecruitingPhase 2/Phase 3
Stem cell transplant trial for children with certain leukemia types
This trial tests whether children and teens with a specific type of acute lymphoblastic leukemia (ALL) do well after getting donor stem cells (an allogeneic transplant). It may help by using a standardized transplant approach for people in complete remission before the transplant.
Buenos AiresAges 1 month–18 years - NCT01666080Recruiting
Second bone marrow transplant with gentler chemotherapy
This trial studies a “reduced intensity” second transplant using donated blood-forming cells, for people whose first transplant did not fully and reliably restart blood production. It aims to improve donor blood cell growth while using a less harsh conditioning approach.
Minneapolis, MinnesotaAges Up to 55 years - NCT01280825Recruiting
Testing how to use genetic medicine results in routine care
This study looks at how to put genetic testing results (pharmacogenomics) into regular doctor care. It aims to see whether using the results helps doctors choose safer, better-matched medications.
Chicago, IllinoisAges 18 years+ - NCT01852370Enrolling by invitationPhase 1/Phase 2
Lung and bone marrow transplant plan for immune system disorders
This early-phase study tests a step-by-step transplant approach: first replacing the lungs, then doing a bone marrow (stem cell) transplant to treat certain immune deficiency diseases. It may help people whose immune problem has led to severe, end-stage lung disease.
Pittsburgh, PennsylvaniaAges 5–45 - NCT02012699Recruiting
Cancer registry for people with or at risk of cancer
This trial collects health information and samples (a “cancer repository”) to help researchers study cancer and cancer risk. You may be able to join if you’ve had cancer before or if you’re at higher risk or have concerning findings.
Greenwood Village, ColoradoAges 19–110 - NCT01832324Enrolling by invitation
Study the causes of food allergy using blood samples
This study looks for the biological reasons behind food allergies by collecting a small amount of blood. It may help scientists better understand different types of food allergy and eventually improve diagnosis or treatments.
Philadelphia, PennsylvaniaAges 1 month–65 years - NCT01728402Enrolling by invitation
Study of the causes of certain blood cancers
This study looks at what leads to specific blood cancers and related blood disorders. If you have one of the listed conditions (or are being evaluated for it), you may be asked to join research that helps doctors understand why these illnesses happen.
Portland, OregonAges 1 year+ - NCT01999361Recruiting
Prevent new immune reaction after islet transplant failure
This study looks at ways to prevent the body from developing a new harmful immune reaction after an islet transplant no longer works. It may help people who have already lost a transplanted islet graft from getting harder-to-treat immune responses later.
Miami, FloridaAges 18–70 - NCT01999374Recruiting
Long-term follow-up for people with transplanted islet cells
This study checks how well transplanted islet cells are working over time and monitors long-term safety. If you previously received an islet transplant and are still using medicine to prevent rejection, you may be followed again.
Miami, FloridaAges 18–65 - NCT01283295Recruiting
Immune monitoring in organ transplant recipients
This study is looking at the immune system in people who have received or are waiting for an organ transplant. It will help researchers better understand how to care for transplant patients by taking blood and tissue samples.
Atlanta, GeorgiaAges Any age - NCT01353547Recruiting
Study genes and environment in multiple sclerosis risk
This study looks at how genes and life exposures may relate to developing multiple sclerosis (MS) or to MS itself. You may be invited if you have a specific connection to MS or certain past immune-related treatments.
Bethesda, MarylandAges 18 years+
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,069 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,273 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.