Infectious disease
Infections clinical trials
Bacterial, viral, and other infections — from common illnesses to emerging threats. We’re tracking 4,173 recruiting studies in this area right now.
By phase
- Not applicable2,709
- Phase 2360
- Phase 4322
- Phase 1292
- Phase 3284
- Phase 1/Phase 2141
- Phase 2/Phase 365
Top conditions
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)89
- Assistance Publique - Hôpitaux de Paris80
- University of California, San Francisco44
- Johns Hopkins University32
- Hospices Civils de Lyon30
- National Cancer Institute (NCI)28
- University of Washington27
- University Hospital, Strasbourg, France26
- Columbia University23
- University of Alabama at Birmingham23
Where studies are running
- California235
- Maryland147
- Alabama89
- New York77
- Florida74
- Texas61
- Massachusetts56
- Arizona46
- Pennsylvania45
- Illinois42
Recruiting studies4,173 total
- NCT03945448RecruitingPhase 2/Phase 3
Single-dose antifungal for people with HIV and positive cryptococcal blood test
This study tests whether a one-time antifungal treatment can help people with HIV who have a positive cryptococcal antigen blood test but no symptoms. It may lower the chance that this infection becomes a serious illness affecting the brain.
KampalaAges 15 years+ - NCT03948048Recruiting
ECMO timing study for children with hard-to-treat septic shock
This trial looks at whether and when a heart-lung machine called ECMO should be used in children whose septic shock is not responding to standard treatment. It may help doctors choose the best timing to improve survival and recovery in the PICU.
ShanghaiAges 4 weeks–18 years - NCT03956446Recruiting
Testing blood antibody patterns in tick-borne brain and Lyme illness
This study looks at blood antibody test results in adults who may have tick-borne encephalitis and also signs of Lyme disease. It may help researchers understand how these infections relate and which lab patterns fit different illnesses.
LjubljanaAges 18 years+ - NCT03963622Recruiting
Test of careful breathing support for severe lung distress
This study compares a more careful ventilation approach for people with severe lung breathing failure (ARDS). It aims to improve outcomes by using a specific strategy for how the ventilator controls breathing.
New York, New YorkAges 18 years+ - NCT03967600Recruiting
Study of hidradenitis suppurativa skin features
This study looks at the physical and biological (body-related) characteristics of hidradenitis suppurativa. It may help researchers understand the condition better and improve future care.
San Francisco, CaliforniaAges 13 years+ - NCT03971669RecruitingPhase 4
Blood donor study testing safety of donating in health
This trial studies people who donate blood and checks what happens in your body after donation, focusing on safety and measurements in lab tests. You may be able to join if you are healthy and pass screening labs and health history checks.
Baltimore, MarylandAges 18 years+ - NCT03992378Recruiting
Nerve stimulation to calm inflammation in sepsis
This trial tests a form of nerve stimulation to help control the body’s overactive inflammation and “autonomic” nervous system imbalance during sepsis. It may help stabilize blood pressure and reduce complications, depending on the cause of your symptoms.
Oklahoma City, OklahomaAges 18 years+ - NCT04899765RecruitingPhase 4
Measles and BCG shots for moms and toddlers
This trial tests whether giving measles and BCG vaccines to mothers and their children after the child turns 12 months is safe and helpful. It specifically looks at women who are not pregnant and meet several health and study-area requirements.
Bissau, Bissau CodexAges 15–35 - NCT07285213RecruitingPhase 2
Preventing C. diff return with an antibody
This study tests a new antibody (AZD5148) to prevent C. diff infection from coming back. If you have a current C. diff infection and are being treated with antibiotics, you may be able to join.
Phoenix, ArizonaAges 18 years+ - NCT06022146RecruitingPhase 3
Short TB prevention for school contacts
This trial tests a very short (one-month) medicine course to prevent tuberculosis (TB) in students and school staff who have been exposed to someone with active TB. If you have latent TB infection (the germs are in your body but you're not sick), this treatment aims to stop it from turning into active TB disease.
Anshun, GuiyangAges 13 years+ - NCT07702916Enrolling by invitation
Hygiene and menstruation study for girls in Madagascar
This trial looks at how hygiene and menstrual health programs affect learning and emotional well-being. If you are a girl in the Kilonga 2 study, you may be asked to complete surveys and some tests, and possibly provide saliva or blood samples.
AntananarivoAges 11–21 - NCT06878144Recruiting
Mucormycosis research for cancer patients with infections
This study gathers samples and data from cancer patients who have certain infections (like mucormycosis or aspergillosis) or are at risk for fungal infections. The goal is to better understand how to diagnose and treat these infections.
Houston, TexasAges 18–100 - NCT06201494Recruiting
Studying early symptoms of asthma in children
This study follows children and teens who are being checked for asthma for the first time. It aims to learn more about the early symptoms of asthma to improve diagnosis and treatment.
PragueAges 3–18 - NCT07133997RecruitingPhase 1
Combination therapy for relapsed CD19+ B-cell leukemia
This trial tests a new combination of three drugs for patients with relapsed or treatment-resistant CD19-positive B-cell acute lymphoblastic leukemia. It aims to see if adding the drugs venetoclax and asparaginase to blinatumomab can improve outcomes.
Duarte, CaliforniaAges 12–55 - NCT04006808RecruitingPhase 1/Phase 2
Shingles prevention vaccine study for kids with kidney transplants
This study tests whether an investigational shingles (herpes zoster) vaccine is safe and helps prevent shingles in children who have had a kidney transplant. Because these children take medicines to prevent rejection, the study specifically looks at vaccine effects in this higher-risk group.
BrusselsAges 1–17 - NCT04013802RecruitingPhase 1
Multivirus T-cell treatment for EBV, CMV, adenovirus, and BK after transplant
This Phase 1 study tests an “off-the-shelf” type of immune cell therapy made to attack several viruses (EBV, CMV, adenovirus, and BK, and possibly JC) in people who had an allogeneic stem cell transplant and still have ongoing viral infection. It may help your body control the virus when standard treatments have not worked or you cannot tolerate them.
Houston, TexasAges Any age - NCT04014413Recruiting
Fecal transplant for gut and immune-related conditions
This trial studies whether fecal microbiota transplantation (FMT)—a medical procedure using stool from a screened donor to restore gut bacteria—can improve safety and outcomes for people with certain bowel, immune, and metabolic conditions. It may help if your symptoms are thought to be related to an unhealthy gut microbiome, though eligibility is broad and depends on specific safety factors.
Hong Kong, ShatinAges Any age - NCT04020536Recruiting
Real-world study for several infectious diseases
This study follows people with confirmed brucellosis, epidemic hemorrhagic fever, or kala-azar (visceral leishmaniasis) to understand how these infections behave in real life. It may help improve care by collecting evidence on diagnosis and treatment outcomes.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT04030676Recruiting
Test for CMV reactivation risk during ulcerative colitis flare
This study checks whether a blood test (QuantiFERON-CMV, related to prior CMV infection) can predict if CMV might reactivate during a severe ulcerative colitis flare. It may help doctors spot people at higher risk and potentially guide monitoring and treatment during hospitalization.
LyonAges 18 years+ - NCT04033224Recruiting
Blood-filter treatments for ICU patients with kidney and organ failure
This trial tests a specific type of blood-filter treatment in critically ill ICU patients who have acute kidney injury and/or failure of other organs. It aims to see whether these filters can improve care by supporting kidney function and/or calming harmful inflammation.
Empoli, FirenzeAges Any age - NCT04033614Recruiting
Device to help close an open abdomen between surgeries
This study looks at a device (“Fasciotens”) used to help manage an open abdomen and support closure during planned or necessary return surgeries. It aims to see how safely and effectively the device works in people who need a temporary open belly treatment.
Aachen, North Rhine-WestphaliaAges 18 years+ - NCT04042857Recruiting
Gel treatment for toenail fungus
This trial tests how well and how safely an antifungal gel works for toenail fungus in adults. You may be able to join if your toenail fungus is confirmed with lab tests and you can follow the study rules during the study.
South Miami, FloridaAges 18 years+ - NCT04048304Recruiting
Shorter antibiotic course after spine infection surgery
This study tests whether giving a shorter course of antibiotics after surgery for a bacterial spine infection is as safe and effective as the usual longer course. It may help some people avoid side effects and reduce total antibiotic exposure—while still keeping the infection controlled.
Zurich, Canton of ZurichAges 18 years+ - NCT04052022Recruiting
Study of TB flare-ups in people without HIV
This study looks at why some people with tuberculosis (TB) get worse or develop new inflammation after they initially start improving on treatment—called a “paradoxical reaction.” It collects blood and tissue samples to better understand these flare-ups and guide future care.
Bethesda, MarylandAges 18–99
Common questions
- How many infections clinical trials are recruiting?
- Clin2 is tracking 4,173 recruiting infectious disease studies from the U.S. registry right now, out of 7,061 we cover in this area in total.
- What does “Infections” cover here?
- Bacterial, viral, and other infections — from common illnesses to emerging threats. We group each study into infections based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a infections trial near me?
- Use the search to filter infections studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.