Infectious disease
Infections clinical trials
Bacterial, viral, and other infections — from common illnesses to emerging threats. We’re tracking 4,173 recruiting studies in this area right now.
By phase
- Not applicable2,709
- Phase 2360
- Phase 4322
- Phase 1292
- Phase 3284
- Phase 1/Phase 2141
- Phase 2/Phase 365
Top conditions
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)89
- Assistance Publique - Hôpitaux de Paris80
- University of California, San Francisco44
- Johns Hopkins University32
- Hospices Civils de Lyon30
- National Cancer Institute (NCI)28
- University of Washington27
- University Hospital, Strasbourg, France26
- Columbia University23
- University of Alabama at Birmingham23
Where studies are running
- California235
- Maryland147
- Alabama89
- New York77
- Florida74
- Texas61
- Massachusetts56
- Arizona46
- Pennsylvania45
- Illinois42
Recruiting studies4,173 total
- NCT04057924Recruiting
Watchful waiting for certain abnormal cells in the cervix
This trial checks whether “therapy abstention” (not treating right away) and close monitoring is safe for certain high-grade cervical cell changes. It may help some people avoid immediate procedures while still catching any progression early.
BordeauxAges 18 years+ - NCT04065971RecruitingPhase 4
Test drug for frequent cold sores in the mouth
This trial tests whether 2LHERP® can reduce or manage frequent herpes infections around the mouth. It compares the study drug to a placebo (inactive treatment) in people who get many episodes each year.
BeerzelAges 16–80 - NCT04083417RecruitingPhase 4
Sore throat study comparing antibiotics versus no antibiotics
This trial looks at whether phenoxymethylpenicillin (an antibiotic) helps people with a certain type of sore throat more than not using antibiotics. You may qualify if your symptoms match a likely bacterial cause and a rapid test for strep is negative.
JönköpingAges 15 years+ - NCT04094311RecruitingPhase 3
Testing a modified cell therapy when product quality is off-spec
This study looks at using tisagenlecleucel, a cell therapy, when the final product does not meet routine “commercial release” quality standards. It focuses on whether it can still be given safely and effectively to people with serious or life-threatening illness.
Hamilton, OntarioAges birth–100 years - NCT04095572RecruitingPhase 4
Prevention options for recurring bladder infections in women
This trial studies different ways to prevent repeated bladder (urinary tract) infections in women. It may help people who keep getting these infections by testing safer or more effective prevention strategies.
BaselAges 18–70 - NCT04095676Recruiting
Surgery vs drainage for infected fluid around the lung
This trial compares two ways to treat pleural empyema, which is infected fluid and pus around the lung. It looks at whether a minimally invasive surgery (VATS) works better than drainage in helping people recover.
Aarhus, AarhusAges 18 years+ - NCT04098315Recruiting
HIV drug-resistance patient registry study for people 14+
This study is a registry (a way to collect and organize information) for people living with HIV who have drug-resistant virus. It may help researchers better understand how resistant HIV behaves and how to manage treatment over time.
Milan, MIAges 14 years+ - NCT04098744RecruitingPhase 2
Artesunate vaginal inserts for high-grade cervical changes
This Phase 2 study tests whether artesunate vaginal inserts can help treat high-grade abnormal cells on the cervix (CIN2/3). It’s meant for adults who have a confirmed high-grade precancer change and can use birth control during the study.
Fort Myers, FloridaAges 25–100 - NCT04103268Recruiting
Study blood tests to understand organ injury in children with sepsis
This study uses special blood testing to learn what is happening in the immune system during sepsis in children and how it may relate to organ injury. Your results may help doctors recognize and treat sepsis earlier and more accurately.
Boston, MassachusettsAges 1 month–17 years - NCT04103281Recruiting
Blood test study of immune cell markers in ICU sepsis
This trial looks at patterns in certain immune cells (neutrophils) in people with sepsis in the ICU, including those who have a breathing tube. It may help doctors better understand how the immune system changes during sepsis and could guide future care.
Boston, MassachusettsAges 2–50 - NCT04115566Recruiting
HS patient registry and sample storage study
This study enrolls people with hidradenitis suppurativa (HS) to better understand the condition over time and store optional health information and samples. Being in the registry may help researchers learn about patterns in HS and support future research.
San Francisco, CaliforniaAges 10 years+ - NCT04128189RecruitingPhase 3
Shingrix vaccine for people waiting for a kidney transplant
This Phase 3 study tests whether the shingles vaccine Shingrix is safe and effective for adults with chronic kidney failure who are on the transplant waiting list. It aims to protect you from shingles while you may be dealing with transplant-related immune changes.
Aurora, ColoradoAges 18–70 - NCT04130789Recruiting
Personalized study for ICU patients with possible sepsis
This study looks at ICU patients in Swiss university hospitals to understand how to personalize care for people who meet sepsis criteria. It may help doctors better predict who is getting worse and tailor treatment plans.
BaselAges 18 years+ - NCT04139850Recruiting
Study of adults with chronic hepatitis B in Korea
This study follows adults with long-term hepatitis B to better understand their health over time and improve care. If you have chronic hepatitis B and can do regular check-ins, you may be invited to join.
SeoulAges 19 years+ - NCT04140578RecruitingPhase 4
Antibiotic prevention for certain liver disease patients
This trial tests whether taking preventive antibiotics can help people with certain liver conditions avoid infections after an endoscopy-related procedure. It may reduce infection risk, but it also requires that you have no signs of infection and haven’t recently taken antibiotics.
TaipeiAges 20–85 - NCT04140903RecruitingPhase 4
Oral antibiotics after 14 days for bacterial brain abscess
This trial looks at whether continuing treatment for a bacterial brain abscess using partially oral antibiotics works as well as the usual approach. It may help people who have already had 14 days of antibiotic treatment and are stable enough to take medicines by mouth.
AalborgAges 18 years+ - NCT04142047Recruiting
Study muscle energy and fatigue in older adults
This study measures how older adults’ muscles use energy and how easily they tire during activity. It includes both people with HIV (with stable treatment and an undetectable viral load) and people without HIV to better understand differences in fatigue.
Baltimore, MarylandAges 60–90 - NCT04145258RecruitingPhase 3
Stronger TB treatment for meningitis to reduce deaths
This trial tests if giving a stronger combination of TB drugs for meningitis can save more lives. It's for patients who have been diagnosed with tuberculosis meningitis and have not yet started more than 5 days of TB treatment.
AbidjanAges 15 years+ - NCT04147286RecruitingPhase 2/Phase 3
Atorvastatin to lower lingering inflammation after TB treatment
This trial studies whether atorvastatin (a cholesterol medicine) can reduce ongoing inflammation after you finish standard tuberculosis (TB) treatment. If it works, it may improve how your body recovers after TB, especially by lowering inflammation-related signals.
Observatory, WCAges 18–65 - NCT04150497RecruitingPhase 1/Phase 2
Testing a new cell therapy for CD22-positive leukemia
This trial tests UCART22, a new cell-based treatment, for people with relapsed or refractory B-cell acute lymphoblastic leukemia (B-ALL) that has the CD22 marker. It may help by attacking leukemia cells that carry CD22.
Los Angeles, CaliforniaAges 15–50 - NCT04160429Recruiting
Biospecimen testing to measure chemicals during treatment
This trial collects small samples like blood, sweat, and saliva while you’re taking certain medicines. Researchers will analyze these samples to see if they can detect chemical levels, which may help improve monitoring for people with chronic or infection-related illnesses.
Duarte, CaliforniaAges 18 years+ - NCT04160455Recruiting
Study of GALIG proteins in adults with HIV on or off treatment
This study looks at how “GALIG” gene products affect the body’s internal recycling process (called autophagy) in people living with HIV. It may help researchers understand differences between people on HIV treatment, starting treatment, or not currently taking it.
OrléansAges 18 years+ - NCT04166266Recruiting
Study of adults with hepatitis D and hepatitis B coinfection
This study follows adults who have ongoing hepatitis D infection along with hepatitis B. It aims to better understand this mixed infection and how these patients do over time.
AngersAges 18 years+ - NCT04168866Recruiting
Appendicitis abscess treatment: drain surgery or antibiotics
This study compares two ways to treat appendicitis that has formed an abscess or firm inflammatory mass (phlegmon) on a CT scan. It aims to see which approach works better and is safer for people with complicated appendicitis.
New Haven, ConnecticutAges 18 years+
Common questions
- How many infections clinical trials are recruiting?
- Clin2 is tracking 4,173 recruiting infectious disease studies from the U.S. registry right now, out of 7,061 we cover in this area in total.
- What does “Infections” cover here?
- Bacterial, viral, and other infections — from common illnesses to emerging threats. We group each study into infections based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a infections trial near me?
- Use the search to filter infections studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.