Nephrology & urology
Kidney & urinary clinical trials
Kidney disease and conditions of the bladder and urinary tract. We’re tracking 4,501 recruiting studies in this area right now.
By phase
- Not applicable2,817
- Phase 2565
- Phase 1364
- Phase 3273
- Phase 1/Phase 2230
- Phase 4194
- Phase 2/Phase 358
Top conditions
- Prostate Cancer650
- Bladder Cancer190
- Acute Kidney Injury136
- Chronic Kidney Diseases131
- Chronic Kidney Disease105
- Breast Cancer104
- Renal Cell Carcinoma80
- Urinary Incontinence65
- Colorectal Cancer60
- Kidney Cancer60
- Ovarian Cancer60
- Lung Cancer55
- Lupus Nephritis54
- Cancer51
- Melanoma50
- Benign Prostatic Hyperplasia48
- Prostate Cancer (Adenocarcinoma)47
- Head and Neck Cancer45
Leading sponsors
- Mayo Clinic61
- National Cancer Institute (NCI)45
- Peking University First Hospital38
- M.D. Anderson Cancer Center36
- Novartis Pharmaceuticals35
- Chinese University of Hong Kong34
- AstraZeneca31
- Memorial Sloan Kettering Cancer Center29
- Assistance Publique - Hôpitaux de Paris28
- University of California, San Francisco28
Where studies are running
- California350
- Alabama112
- Arizona104
- New York96
- Florida95
- Maryland92
- Texas91
- Massachusetts88
- Illinois67
- Ohio48
Recruiting studies4,501 total
- NCT05373264RecruitingPhase 3
Hydrochlorothiazide to help polycystic kidney disease and quality of life
This Phase 3 study tests whether hydrochlorothiazide can help people with autosomal dominant polycystic kidney disease (ADPKD) and improve quality of life. It also looks at whether it affects kidney health while you stay on your current ADPKD-related treatment.
GrazAges 18–80 - NCT02402244Recruiting
Caring registry study for children and young people with cancer
This study keeps a careful record of children, teens, and young adults with cancer (and some related growths) and may follow them over time. It helps researchers better track outcomes and future contact so care can improve.
Birmingham, AlabamaAges Up to 25 years - NCT07608874Recruiting
Comparing stitching techniques to reduce scar problems after first cesarean
This trial compares two ways of closing the uterus during a planned cesarean section to see which creates a stronger scar and prevents complications. If you're having your first cesarean delivery, this research may help doctors improve the procedure.
Baden, Canton of AargauAges 18 years+ - NCT07579195RecruitingPhase 1/Phase 2
Consolidation therapy after EV + pembro in bladder cancer
This trial tests whether adding radiation therapy or bladder-removal surgery (consolidation) after EV + pembrolizumab helps control muscle-invasive bladder cancer that has spread. It is for people whose cancer responded to the initial drug combination.
Seattle, WashingtonAges 18 years+ - NCT05738304Recruiting
Do we need a stent after kidney stone surgery?
This study looks at whether placing a temporary tube (called a stent) in the ureter after kidney stone surgery is always necessary. Some patients get a stent to help urine flow, but it can cause discomfort. The trial aims to see if skipping the stent is safe and leads to fewer symptoms. If you are having kidney stone surgery, participating might help determine the best approach for recovery.
CairoAges 18 years+ - NCT05213572Recruiting
Deep health check study for adults with sickle cell disease
This study looks at how major organs like the brain, kidneys, heart, and liver are affected in adults with sickle cell disease, whether they've had a bone marrow transplant or gene therapy, or are continuing regular treatment. You'll get detailed tests that can help doctors understand the disease better, which may lead to improved care.
Bethesda, MarylandAges 18–100 - NCT07781267Recruiting
Long-term outcomes of congenital adrenal hyperplasia
This study looks at the long-term experiences of adults with classic congenital adrenal hyperplasia (CAH), a condition affecting hormone production. It aims to understand patient satisfaction and health outcomes over time.
LilleAges 18–65 - NCT07781124Recruiting
Remote monitoring for kidney dialysis patients
This study compares the effectiveness and resource use of remote patient monitoring across different dialysis methods for people with end-stage renal disease. It aims to see if remote monitoring can improve care and outcomes.
Beijing, Beijing MunicipalityAges 18–79 - NCT07222488RecruitingPhase 1/Phase 2
Study of MK-3120 for bladder cancer
This trial tests a new drug, MK-3120, for people with a specific type of bladder cancer that hasn't spread into the muscle. It is for patients who either haven't had BCG treatment before or have had BCG treatment and their cancer came back more than 12 months but within 2 years after the last dose.
Bakersfield, CaliforniaAges 18 years+ - NCT06136650RecruitingPhase 3
Study of a new drug for advanced prostate cancer
This study tests a new oral drug called opevesostat against another standard hormone therapy for men with advanced prostate cancer that has spread and is no longer controlled by a first hormone therapy. It's for men who have not had chemotherapy for this stage and who have not used a PARP inhibitor or chose not to.
Tucson, ArizonaAges 18 years+ - NCT07759752Recruiting
Two minimally invasive treatments for enlarged prostate symptoms
This trial compares two minimally invasive procedures to relieve urinary symptoms caused by an enlarged prostate. Both treatments aim to open the urethra without major surgery, and the goal is to improve your urine flow and reduce bothersome symptoms.
Hong KongAges 50–80 - NCT07753876Enrolling by invitation
Cuffless blood pressure monitoring during dialysis
This study tests a wearable device that measures blood pressure without a cuff while you are on dialysis. It may give a more comfortable way to track your blood pressure during treatment.
SeoulAges 19 years+ - NCT07053800RecruitingPhase 2
Obe-cel for severe lupus with kidney inflammation
This trial tests a new cell therapy called obe-cel in people ages 12 to 65 with severe systemic lupus erythematosus (SLE) that has not responded to other treatments and has caused active lupus nephritis (kidney disease). The goal is to see if obe-cel can reduce lupus activity and improve kidney health.
New York, New YorkAges 12–65 - NCT05898932Recruiting
Help improve BPH care using patient health questionnaires
This study tests a better way to manage benign prostatic hyperplasia (BPH) by using your answers to regular health questionnaires. It may help your care team make more informed decisions about your symptoms and treatment over time.
Glenview, IllinoisAges 50 years+ - NCT05951179RecruitingPhase 2
Bladder instillation study for high-grade non–muscle-invasive cancer
This Phase 2 trial tests TARA-002 given directly into the bladder to treat high-grade non–muscle-invasive bladder cancer with active disease. It may help patients who have not previously responded to, or have not received, BCG treatment in the recent past.
Homewood, AlabamaAges 18 years+ - NCT07444489Enrolling by invitationPhase 3
Long-term safety of felzartamab for kidney transplant rejection
This study checks the long-term safety of felzartamab for people who have had a kidney transplant and are dealing with antibody-mediated rejection or signs of inflammation in the kidney. It's for those who were already in a previous study and took at least one dose of felzartamab.
Los Angeles, CaliforniaAges 18–75 - NCT06711887RecruitingPhase 3
Long-term extension study of ianalumab for lupus nephritis
This study is a follow-up for people with lupus nephritis who already completed a 144-week treatment course with ianalumab in an earlier study. It tests whether continuing or stopping the drug is safe and effective over the long term.
Orchard Park, New YorkAges 18–100 - NCT05997615RecruitingPhase 1
Study of VIR-5500 for advanced prostate cancer
This trial tests VIR-5500 (AMX-500), a new targeted treatment, in men with prostate cancer that has spread and stopped responding to standard therapies. The goal is to see if it is safe and if it may help shrink or slow the cancer.
Palo Alto, CaliforniaAges 18 years+ - NCT07456865Recruiting
Device for Urge Incontinence: Long-Term Effectiveness Study
This trial tests a device that sends mild electrical pulses to a nerve in your ankle to help control sudden, strong urges to urinate (urinary urge incontinence). It is designed for people who have not had success with other treatments.
Homewood, AlabamaAges 18 years+ - NCT05614739RecruitingPhase 1
Study of vepugratinib for cancers with FGFR3 gene changes
This study tests a new pill, vepugratinib, for people whose cancer has a specific change in a gene called FGFR3. The drug targets this gene change to try to slow or shrink the cancer, and may be an option if standard treatments have not worked.
Tucson, ArizonaAges 18 years+ - NCT07776626RecruitingPhase 1
Study of YOLT-203 for Primary Hyperoxaluria Type 1
This study tests a new treatment for primary hyperoxaluria type 1, a rare condition that causes too much oxalate in the body, which can lead to kidney stones and kidney damage. The treatment is given as an injection, and the study will see if it is safe and how the body responds.
Shanghai, Shanghai MunicipalityAges 6 years+ - NCT07129993RecruitingPhase 2/Phase 3
Study of datopotamab deruxtecan with chemo for advanced bladder cancer
This trial is testing a new drug combination for advanced bladder cancer that has grown despite previous treatment. It pairs a targeted therapy (datopotamab deruxtecan) with chemotherapy, and the goal is to see if it can slow down or stop the cancer better than standard chemo alone.
Fullerton, CaliforniaAges 18 years+ - NCT05465044Recruiting
Twice-weekly dialysis for veterans starting kidney treatment
This study compares starting hemodialysis two times per week versus three times per week for veterans in their first year of dialysis. It aims to see if a less frequent schedule can be just as safe and effective for those who still make urine.
Long Beach, CaliforniaAges 18 years+ - NCT07776574Recruiting
Kidney health after deep endometriosis surgery
This study looks at how deep endometriosis that affects the urinary tract (ureters and kidneys) impacts kidney function over time. It compares patients who had surgery for this condition at least two years ago with patients who are about to have surgery, to understand long-term kidney health.
PragueAges 18 years+
Common questions
- How many kidney & urinary clinical trials are recruiting?
- Clin2 is tracking 4,501 recruiting nephrology & urology studies from the U.S. registry right now, out of 7,121 we cover in this area in total.
- What does “Kidney & urinary” cover here?
- Kidney disease and conditions of the bladder and urinary tract. We group each study into kidney & urinary based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a kidney & urinary trial near me?
- Use the search to filter kidney & urinary studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.