Nephrology & urology
Kidney & urinary clinical trials
Kidney disease and conditions of the bladder and urinary tract. We’re tracking 4,504 recruiting studies in this area right now.
By phase
- Not applicable2,821
- Phase 2564
- Phase 1366
- Phase 3271
- Phase 1/Phase 2230
- Phase 4194
- Phase 2/Phase 358
Top conditions
- Prostate Cancer651
- Bladder Cancer191
- Acute Kidney Injury136
- Chronic Kidney Diseases131
- Breast Cancer104
- Chronic Kidney Disease104
- Renal Cell Carcinoma80
- Urinary Incontinence64
- Colorectal Cancer60
- Kidney Cancer60
- Ovarian Cancer60
- Lung Cancer55
- Lupus Nephritis54
- Cancer51
- Melanoma50
- Benign Prostatic Hyperplasia48
- Prostate Cancer (Adenocarcinoma)46
- Renal Cancer46
Leading sponsors
- Mayo Clinic62
- National Cancer Institute (NCI)45
- Peking University First Hospital38
- M.D. Anderson Cancer Center36
- Novartis Pharmaceuticals35
- Chinese University of Hong Kong34
- AstraZeneca30
- Memorial Sloan Kettering Cancer Center29
- Assistance Publique - Hôpitaux de Paris28
- University of California, San Francisco28
Where studies are running
- California350
- Alabama112
- Arizona103
- Florida97
- New York95
- Maryland91
- Texas91
- Massachusetts88
- Illinois66
- Ohio48
Recruiting studies4,504 total
- NCT05467033RecruitingPhase 3
Desmopressin to improve safety after kidney biopsy
This trial tests whether desmopressin can make kidney biopsy safer by reducing bleeding risk. It compares safety outcomes after a biopsy in people who meet specific blood, medication, and health criteria.
BialystokAges 18–99 - NCT06491108RecruitingPhase 3
Medication for moderate prostate symptoms in sexually active men
This study tests whether a medication can help men with moderate urinary symptoms from an enlarged prostate. It's for men who are already on prostate medicine and have been closely monitored for 12 weeks.
Tanta, Gharbia GovernorateAges 40–70 - NCT07461233Recruiting
Gut Health and Synbiotics in Hemodialysis
This study tests whether taking a special mix of friendly bacteria and prebiotics (called synbiotics) can help improve gut health in people on hemodialysis. It may reduce inflammation and other complications related to kidney disease.
Taichung, Wuqi DistrictAges 18 years+ - NCT06464822Recruiting
Effects of weight-loss surgery on urinary symptoms
This study looks at whether weight-loss surgery can improve urinary symptoms like needing to pee often or suddenly. It is for people with severe obesity who are already being seen at a specific clinic for bariatric surgery.
Hong KongAges 18 years+ - NCT05654506RecruitingPhase 2
Daratumumab for kidney disease caused by immune deposits
This Phase 2 study tests daratumumab (an immune-targeting medicine) in people with PGNMID, a kidney disease where abnormal immune proteins build up in the kidney filters. It aims to reduce harmful protein in the urine and improve kidney health.
Jacksonville, FloridaAges 18 years+ - NCT05490225Recruiting
Test device to make dialysis fistulas easier to stick safely
This trial tests a small implant device that can make dialysis fistulas easier to access with needles when normal needle access is too difficult or risky. It may help reduce painful failed attempts and needle-related complications for people with certain types of fistulas.
Dothan, AlabamaAges 18 years+ - NCT07208682Recruiting
Bladder safety during sling surgery study
This study tests a technique to reduce bladder injury during a common sling procedure for stress urinary incontinence. It may help patients avoid complications.
Worcester, MassachusettsAges 18 years+ - NCT06428708RecruitingEarly Phase 1
PSMA PET scan for metastatic kidney cancer
This trial uses a special PET scan called PSMA to see if it can better detect kidney cancer that has spread. It may help find tumors that other scans miss.
London, OntarioAges 18 years+ - NCT07485205Recruiting
Bladder pressure study in healthy adults
This study collects normal bladder pressure data from healthy adults using a new device. It helps doctors understand what healthy bladder function looks like, which may improve future care.
Phoenix, ArizonaAges 18–45 - NCT06380738Recruiting
Real-world study of olaparib plus abiraterone for advanced prostate cancer
This trial is for people with advanced prostate cancer (mCRPC) who are already taking the combination of olaparib and abiraterone. It will look at how these two medicines work together in real-world practice.
AschaffenburgAges 18 years+ - NCT06379009Recruiting
Home exercise program for kidney transplant recipients
This trial tests a home-based exercise program for people who have recently had a kidney transplant. It aims to help you improve your physical function and recovery after surgery.
OsloAges 18 years+ - NCT06568549RecruitingPhase 4
Reducing Immunosuppression in Older Kidney Transplant Patients (RIOT Trial)
This trial tests whether older kidney transplant recipients can safely reduce their immunosuppression medications using a special monitoring tool called Trugraf. If you are over 55, have had a stable transplant, and want to possibly lower your medications, this study may be for you.
Phoenix, ArizonaAges 55 years+ - NCT06374121Recruiting
Kidney preservation with or without machine perfusion
This study compares two ways of preserving kidneys from older or less healthy donors before transplant – one using a machine that pumps fluid through the kidney, and one without. It may help improve how well these kidneys work after transplant.
Bergamo, BGAges 50 years+ - NCT07469072RecruitingPhase 2
Nafamostat doses for dialysis blood thinning in ICU
This trial is testing different doses of a blood thinner called nafamostat in patients who are in the ICU and need continuous kidney dialysis (CRRT). The goal is to find which dose works best to prevent clots in the dialysis machine without causing bleeding problems.
Guangzhou, GuangdongAges 18–80 - NCT06089057Enrolling by invitation
Social exercise program for aging with kidney disease
This study tests a program to help people with chronic kidney disease who are starting to feel frail (weak or slow). It uses social activities and gentle exercise to improve well-being and strength.
Nashville, TennesseeAges Any age - NCT05354375RecruitingPhase 1
PSMA-targeted CAR-T cell therapy for resistant prostate cancer
This Phase 1 study tests whether lab-made immune cells (CAR-T) that target PSMA can treat prostate cancer that keeps growing despite hormone treatment. It may help people whose disease no longer responds to standard endocrine (hormone-blocking) therapy.
Xuzhou, JiangsuAges 18–75 - NCT06794216Recruiting
Comparing dialysis methods to clean blood in kidney failure
This study compares different types of dialysis to see which removes waste products (uremic toxins) best from the blood. If you have been on dialysis for at least 6 months and use the same filter for a year, this trial may help find a better way to clean your blood.
Bologna, Emilia-RomagnaAges 18 years+ - NCT06344442RecruitingPhase 3
Low-dose vasopressin for kidney protection after liver transplant
This trial tests whether giving a low dose of a hormone called vasopressin after a liver transplant can help prevent kidney injury. It's for adults scheduled for a planned liver transplant.
ParisAges 18 years+ - NCT06335914Recruiting
Dual PET scans for advanced prostate cancer
This study tests whether two kinds of PET scans, one targeting PSMA and one targeting sugar uptake (FDG), can help doctors better understand advanced prostate cancer. If you have prostate cancer that has spread (metastatic) and still responds to hormone therapy, the scans may help guide your treatment.
Toronto, OntarioAges 18 years+ - NCT06325995Recruiting
Short radiation course after prostate surgery for rising PSA
This trial tests a shorter, stronger course of radiation (hypofractionated radiotherapy) given after prostate removal surgery. It may help people whose PSA levels rise again after surgery, aiming to reduce side effects and improve outcomes.
Shanghai, Shanghai MunicipalityAges Any age - NCT06334120Recruiting
Darolutamide safety study for men with prostate cancer in Korea
This study tracks the safety of the drug darolutamide in Korean men with a type of prostate cancer that has not spread (non-metastatic) or has spread (metastatic) and is still responding to hormone therapy. It aims to see how well patients tolerate the drug in real-world settings.
Multiple LocationsAges 19 years+ - NCT06335667Recruiting
MRI vs. TURBT for muscle-invasive bladder cancer
This study compares two ways to check if bladder cancer has grown into the muscle layer: an MRI scan (mpMRI) versus a standard surgery called TURBT (where a small tool removes a sample of the tumor). The goal is to see if the MRI can be as accurate as the surgery, so future patients might avoid an extra procedure.
Orange, CaliforniaAges 18 years+ - NCT07476001RecruitingPhase 2
High-dose testosterone and PSMA-targeted radiation for prostate cancer
This trial tests whether a short course of high-dose testosterone followed by a radioactive drug (PSMA-617) can help men with advanced prostate cancer that has stopped responding to hormone therapy. The goal is to make cancer cells more sensitive to the radiation.
Tampa, FloridaAges 18 years+ - NCT06335537RecruitingPhase 1
Can baking soda help prevent kidney stones?
This study tests if adding baking soda (sodium bicarbonate) to your current medication (Urocit-K) helps lower stone-forming chemicals in your urine. It is for people who have low citrate or uric acid stones and are already taking Urocit-K.
Orange, CaliforniaAges 18–80
Common questions
- How many kidney & urinary clinical trials are recruiting?
- Clin2 is tracking 4,504 recruiting nephrology & urology studies from the U.S. registry right now, out of 7,162 we cover in this area in total.
- What does “Kidney & urinary” cover here?
- Kidney disease and conditions of the bladder and urinary tract. We group each study into kidney & urinary based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a kidney & urinary trial near me?
- Use the search to filter kidney & urinary studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.