Nephrology & urology
Kidney & urinary clinical trials
Kidney disease and conditions of the bladder and urinary tract. We’re tracking 4,505 recruiting studies in this area right now.
By phase
- Not applicable2,822
- Phase 2562
- Phase 1366
- Phase 3271
- Phase 1/Phase 2230
- Phase 4195
- Phase 2/Phase 359
Top conditions
- Prostate Cancer651
- Bladder Cancer192
- Acute Kidney Injury136
- Chronic Kidney Diseases131
- Breast Cancer105
- Chronic Kidney Disease104
- Renal Cell Carcinoma80
- Urinary Incontinence64
- Colorectal Cancer60
- Kidney Cancer60
- Ovarian Cancer60
- Lung Cancer56
- Lupus Nephritis53
- Cancer51
- Melanoma50
- Benign Prostatic Hyperplasia48
- Head and Neck Cancer46
- Prostate Cancer (Adenocarcinoma)46
Leading sponsors
- Mayo Clinic62
- National Cancer Institute (NCI)45
- Peking University First Hospital38
- M.D. Anderson Cancer Center36
- Chinese University of Hong Kong34
- Novartis Pharmaceuticals34
- AstraZeneca29
- Memorial Sloan Kettering Cancer Center29
- Assistance Publique - Hôpitaux de Paris28
- University of California, San Francisco28
Where studies are running
- California350
- Alabama111
- Arizona103
- Florida97
- New York95
- Maryland91
- Texas91
- Massachusetts88
- Illinois66
- Ohio48
Recruiting studies4,505 total
- NCT05022914Recruiting
PSMA PET/CT scan for PSA relapse after prostate surgery
This trial looks at using a PSMA PET/CT scan to better re-check cancer activity in men whose PSA has started rising after prostate removal. If you qualify, the scan may help doctors choose the next best treatment step.
FlorenceAges 18 years+ - NCT05023265Recruiting
Study quality of life after SBRT for kidney cancer
This trial studies how well people do—especially their quality of life—after SBRT radiation for primary kidney cancer that can’t be removed with surgery. It may help doctors understand which patients benefit most and what side effects to expect.
Toronto, OntarioAges 18 years+ - NCT05024162Recruiting
MRI and biopsy study of how prostate tumors grow
This study looks at whether special MRI details can help predict how invasive your prostate cancer tumor is. It combines MRI images with your biopsy results to see if MRI patterns can match how aggressive the cancer may be.
Halifax, Nova ScotiaAges Any age - NCT05024214RecruitingPhase 1/Phase 2
Test of envafolimab plus lenvatinib for advanced solid tumors
This trial studies whether combining envafolimab (an anti-immune cancer medicine) with lenvatinib (a targeted pill) can shrink or control advanced cancers that have stopped responding to standard care. It may help people whose tumors are not curable with usual treatments, by testing a new combo and finding safe doses.
Bengbu, AnhuiAges 18 years+ - NCT05027906RecruitingPhase 1/Phase 2
Study drug AT 1501 for first-time kidney transplant patients
This Phase 1/2 trial tests how safe AT 1501 is and how it works in people getting their first kidney transplant. It aims to improve transplant outcomes by targeting the immune system, while carefully watching for side effects and immune compatibility issues.
Cincinnati, OhioAges 18–100 - NCT05030987Recruiting
Renal denervation for heart failure with preserved heart strength
This trial studies whether a procedure that calms overactive kidney nerves (renal denervation) can improve symptoms and heart function in people with heart failure with preserved ejection fraction. It also checks that the kidney arteries are suitable and that your blood pressure and heart pressure measurements meet the study targets.
Halle, Saxony-AnhaltAges 18–80 - NCT05033301Recruiting
Nurse Ned Clinic support for prostate cancer survivors
This study tests a nurse-led clinic (“Nurse Ned Clinic”) to see how well it supports men after curative (potentially curative) prostate cancer treatment. It may help you manage follow-up care during survivorship if you are at low risk of cancer coming back.
Toronto, OntarioAges 18 years+ - NCT05036850Recruiting
Kidney patient research network follow-up study
This trial is for people with a primary (main) kidney disease who can regularly see a kidney doctor. It sets up and includes patients for possible interventional (active) research studies, which may help improve kidney care for future patients.
Beijing, Beijing MunicipalityAges 2 years+ - NCT05037279RecruitingPhase 3
Testing BCG treatment for bladder cancer after full tumor removal
This trial studies a BCG-based bladder instillation in people with newly diagnosed, intermediate- or high-risk non-muscle invasive bladder cancer who have had their tumor fully removed. The goal is to see whether this treatment is safer and works better to lower the chance of the cancer coming back.
Vancouver, British ColumbiaAges 18 years+ - NCT05037825Recruiting
Study gut microbes with immune therapy in several solid cancers
This trial looks at how the gut microbiome (the bacteria in your digestive system) relates to outcomes when you take standard immune “checkpoint” cancer medicines. If you’re eligible, they’ll collect stool samples while you receive treatment for certain cancers.
Elizabethtown, KentuckyAges 18 years+ - NCT05038332RecruitingPhase 2
Testing two types of radiation after prostate surgery
This Phase 2 study compares two schedules of radiation treatment after prostate surgery in men whose PSA starts rising again. It aims to see which radiation approach works well while tracking quality of life and safety.
Ann Arbor, MichiganAges 18 years+ - NCT05043012Recruiting
Testing a special MRI scan for prostate cancer diagnosis
This study checks how well a new prostate MRI scan (using a flexible coil and multiple MRI types) can correctly identify prostate cancer and help with treatment planning. You may be able to help doctors improve prostate imaging before you have surgery.
Houston, TexasAges 18 years+ - NCT05045066RecruitingEarly Phase 1
Vitamin D treatment study for Black men with prostate cancer
This early-phase study looks at how vitamin D replacement affects the immune system in Black/African American men with prostate cancer. It’s testing whether bringing vitamin D levels into a healthier range changes immune signals that may matter for cancer health.
Scottsdale, ArizonaAges 18 years+ - NCT05048212RecruitingPhase 2
Nivolumab, ipilimumab, and cabozantinib for kidney cancer brain spread
This Phase 2 study tests how well nivolumab plus ipilimumab, along with cabozantinib, treats untreated or worsening kidney cancer that has spread to the brain. It may help shrink brain tumors and slow the disease when standard local brain treatments aren’t the right option.
Houston, TexasAges 18 years+ - NCT05052606Recruiting
Turner syndrome patient registry study
This is a registry study that collects health information from people who have Turner syndrome. It helps researchers better understand the condition and guide future care.
Aurora, ColoradoAges Any age - NCT05054296RecruitingPhase 2
Exercise and Fitbit monitoring to lower heart risk in prostate cancer
This Phase 2 study tests whether a structured exercise and lifestyle program, tracked with a Fitbit, can reduce cardiovascular (heart) risk in men with prostate cancer on hormone therapy. It also checks whether this is safe and feasible while monitoring symptoms and fitness changes.
Houston, TexasAges 18 years+ - NCT05056701Recruiting
Checking early care for kidney disease after pre-eclampsia
This study looks at how to predict and diagnose chronic kidney disease (long-term kidney damage) in people who had pre-eclampsia during pregnancy, including related serious conditions. It may help identify kidney problems earlier so care can start sooner.
AngersAges 18 years+ - NCT05059444Recruiting
Blood test study to watch for cancer coming back
This study looks at whether blood tests can detect signs that cancer may return after curative-intent treatment. You would have blood drawn around your usual follow-up visits for up to 5 years, and your de-identified health data would be shared with study investigators.
Birmingham, AlabamaAges 18 years+ - NCT05060783Recruiting
Liquid blood test to help detect kidney cancer
This study tests whether a “liquid biopsy” blood test can help detect kidney cancer when a CT scan looks suspicious but does not show cancer. It may help avoid unnecessary procedures or catch cancer patterns earlier, but it will depend on the type of kidney tumor and your situation.
RoskildeAges 18 years+ - NCT05062707Recruiting
Study of early aging in young people during cancer treatment
This study looks at how “early aging” changes show up during treatment in young adults with cancer. It may help doctors better understand health effects during curative therapy and improve care for people your age.
GroningenAges 18–39 - NCT05065372RecruitingPhase 1
Metformin test with automated insulin in teens with type 1
This Phase 1 study tests how adding metformin affects blood flow in the kidneys, insulin sensitivity, and overall heart/metabolic health in young people with type 1 diabetes. It may help researchers understand whether this combo is safe and beneficial alongside automated or pump/shot insulin care.
Aurora, ColoradoAges 12–25 - NCT05067101Recruiting
Compare two bladder cancer surgeries in men
This trial compares two types of bladder surgery to see which works better for certain men with bladder cancer. It may help you and your doctors choose the safest option that controls the cancer while preserving quality of life.
Guangzhou, GuangdongAges 20 years+ - NCT05072600RecruitingPhase 2
Pembrolizumab after complete bladder cancer treatment response
This trial studies pembrolizumab (an immunotherapy) in people with muscle-invasive bladder cancer who had a combined “trimodality” treatment and then achieved a complete response. The goal is to help control the cancer after the initial treatment is finished.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05084196RecruitingPhase 3
Melatonin to help prevent kidney damage from vancomycin
This Phase 3 study tests whether melatonin can help protect the kidneys in people who are starting or continuing vancomycin, an antibiotic that can sometimes affect kidney function. If you qualify, you would take melatonin as an added prevention step while you’re on vancomycin.
New Brunswick, New JerseyAges 18–75
Common questions
- How many kidney & urinary clinical trials are recruiting?
- Clin2 is tracking 4,505 recruiting nephrology & urology studies from the U.S. registry right now, out of 7,180 we cover in this area in total.
- What does “Kidney & urinary” cover here?
- Kidney disease and conditions of the bladder and urinary tract. We group each study into kidney & urinary based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a kidney & urinary trial near me?
- Use the search to filter kidney & urinary studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.