Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT06195527Recruiting
Pembrolizumab blood level monitoring for NSCLC
This study checks how well pembrolizumab (Keytruda) works in people with non-small cell lung cancer (NSCLC) by measuring the drug levels in your blood. It aims to see if adjusting the dose based on these levels improves treatment and reduces side effects.
AngersAges 18 years+ - NCT06195540RecruitingPhase 3
Rivaroxaban versus LMWH for leg injuries needing a cast
This trial compares two blood thinners (rivaroxaban pills versus LMWH shots) to see which is better at preventing blood clots in people with leg injuries that require a cast or brace. If you qualify, you can receive one of these treatments while your leg heals.
AgenAges 18 years+ - NCT06196034Recruiting
Genetic study of asthma severity and types
This study looks at how genes are linked to different types and severities of asthma. It aims to understand why asthma affects people differently, which could lead to better treatments.
Hong Kong, New TerritoriesAges 18–100 - NCT06196294RecruitingPhase 1
Engineered immune cells for cancers with GPC3 or mesothelin
This trial tests a new type of immune cell therapy made from your own cells (gamma-delta T cells) that are engineered to find and attack cancers that have GPC3 or mesothelin proteins. It may be an option for people with advanced cancer who have not had gene therapy before and are in generally good health.
Guangzhou, GuangdongAges 18–75 - NCT06197204Recruiting
Finding biomarkers in Langerhans cell histiocytosis
This study is looking for adults with Langerhans cell histiocytosis (LCH) and also for adults with certain lung conditions (like cystic lung disease or emphysema) or healthy smokers to act as controls. The goal is to find biomarkers (signs in the body) that can help doctors diagnose LCH, predict how it will progress, and see how well treatment is working.
ParisAges 18 years+ - NCT06197152Recruiting
RSV severity markers in hospitalized adults
This study looks for markers in the blood that can tell how serious an RSV infection might become. If you are hospitalized with RSV and have breathing symptoms, this trial will follow your recovery and test for clues about your illness.
CréteilAges 18 years+ - NCT06198868Recruiting
MRD blood test to guide treatment in lung cancer
This trial uses a blood test (ctDNA and CTC) to check for minimal residual disease (MRD) after treatment for stage IIA-IIIC non-small cell lung cancer. The goal is to see if MRD can help predict whether the cancer will come back and guide decisions on extra treatment to prevent recurrence.
Nanjing, JiangsuAges 18 years+ - NCT06199895RecruitingPhase 2
Study of paclitaxel for patients with taxane-resistant solid tumors
This trial tests paclitaxel given as tiny micelle particles for people whose cancer (pancreatic, bile duct, lung, stomach, esophagus, or breast) stopped responding to taxane chemotherapy or did not shrink. The goal is to see if this treatment can help when standard taxanes no longer work.
Wuhan, HubeiAges 18 years+ - NCT06199921RecruitingPhase 2
Atorvastatin plus TB treatment for new tuberculosis
This study tests whether adding the cholesterol drug atorvastatin to standard TB treatment helps people recover faster. It is for people with newly diagnosed, drug-sensitive tuberculosis who have not yet started treatment.
Zaria, Kaduna StateAges 12–65 - NCT06201299Recruiting
Chair-based vs standard exercise for COPD
This clinical trial compares a chair-based exercise program with a standard exercise program for people with COPD. If you have COPD and get short of breath with activity, this study may help you find an exercise routine that works for you.
Istanbul, ZeytinburnuAges 18–75 - NCT06201403Recruiting
COPD: Breathing Muscle Strength and Flexibility Study
This study looks at the strength and flexibility of muscles you use to breathe, including muscles in your chest and neck. If you have moderate-to-severe COPD and have been stable on your medications, it may help researchers understand how these muscles are affected.
Istanbul, ZeytinburnuAges 18–75 - NCT06202222Recruiting
Intensive rehab after lung cancer surgery
This trial looks at whether a more intensive exercise program after keyhole surgery for lung cancer helps you recover faster. It involves cycling on a stationary bike while supervised by a physiotherapist.
Valenciennes, Hauts-de-FranceAges 18 years+ - NCT06203405Recruiting
Sedation guided by breathing effort in ICU patients
This trial tests a new way to manage sedation (medication to keep you calm and comfortable) for people on a breathing machine. The goal is to see if adjusting sedation based on your breathing effort leads to better outcomes and shorter time on the machine.
Bangkok, BangkokAges 18 years+ - NCT06204731Recruiting
Exercise in low oxygen for young men
This study tests whether exercising in a low-oxygen environment (like high altitude) can affect stress, inflammation, and energy in your body. It is for young males who are generally healthy and can exercise safely.
KrakowAges 19–29 - NCT06205121RecruitingPhase 2
Testing a new drug for active lung sarcoidosis
This study tests a new medication, OATD-01, for people with active sarcoidosis in their lungs. It aims to see how safe and effective the drug is and if it can improve symptoms.
Birmingham, AlabamaAges 18 years+ - NCT06205927RecruitingPhase 2
Carbon Ion Boost for Advanced Lung Cancer
This trial tests a new way to give radiation therapy (carbon ion boost) to people with advanced, inoperable lung cancer. The goal is to see if targeting the most aggressive parts of the tumor with a higher dose can improve outcomes.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06209047RecruitingPhase 4
Antibiotics via bronchoscopy for bronchiectasis flare-ups
This study tests if giving antibiotics (levofloxacin or gentamicin) directly into the lungs during a bronchoscopy can help patients with bronchiectasis who are in the hospital with a sudden worsening of symptoms or are on a breathing machine.
AsyutAges 18 years+ - NCT06210815RecruitingPhase 1
Testing a new drug HLX42 for advanced solid tumors
This trial tests a new drug called HLX42 for people with advanced solid tumors (including a type of lung cancer called NSCLC) who have no good treatment options left. The goal is to see if it's safe and if it can help shrink tumors.
Guangdong, GuangzhouAges 18–75 - NCT06213532Recruiting
Connect to lung care study for smokers
This study, called CONNECTing to LungCare, helps current smokers who get their primary care at UCSF clinics learn about lung cancer screening. The goal is to make it easier for people to get screened and to support smokers in their health journey.
San Francisco, CaliforniaAges 18 years+ - NCT06216301RecruitingPhase 3
Electric fields with immunotherapy and chemo for advanced lung cancer
This trial tests adding a device that delivers electric fields (Tumor Treating Fields) to standard immunotherapy and chemotherapy for people with advanced non-small cell lung cancer that has not been treated before. It may help slow tumor growth.
Birmingham, AlabamaAges 18 years+ - NCT06216535RecruitingPhase 2
Escitalopram for frequent asthma attacks
This study tests whether the antidepressant escitalopram can reduce asthma attacks in people who have frequent, severe flare-ups despite using their regular inhalers. It may help if you have moderate to severe asthma and have had 3 or more attacks needing steroids in the past year.
Dallas, TexasAges 18–75 - NCT06216704Recruiting
Bone health and marrow study in teens with cystic fibrosis
This study looks at how cystic fibrosis affects bone health and bone marrow in teenagers. It uses a special MRI scan to measure bone strength and marrow composition, which may help doctors better understand and prevent bone problems in people with CF.
Boston, MassachusettsAges 13–20 - NCT06216782Recruiting
Neoadjuvant therapy for lung cancer: a real-world study
This study observes patients with lung cancer who receive neoadjuvant therapy (treatment before surgery) to understand how well it works in everyday medical practice.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06217276Recruiting
Breathing muscle fatigue and leg oxygen in COPD
This study looks at how breathing muscle tiredness relates to oxygen levels in leg muscles for people with moderate-to-severe COPD. It may help patients understand their condition better.
Istanbul, ZeytinburnuAges 18–75
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.