Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,352 recruiting studies in this area right now.
By phase
- Not applicable4,048
- Phase 2834
- Phase 1460
- Phase 3421
- Phase 1/Phase 2312
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer416
- Asthma194
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD134
- Breast Cancer111
- Pulmonary Hypertension105
- Colorectal Cancer89
- COVID-1988
- NSCLC87
- Chronic Obstructive Pulmonary Disease84
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia68
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California385
- Alabama175
- Arizona154
- Florida121
- Massachusetts118
- Maryland115
- New York111
- Texas87
- Pennsylvania82
- Illinois73
Recruiting studies6,352 total
- NCT06959251Recruiting
Glycine and magnesium with thiamine for primary ciliary dyskinesia
This trial tests whether a combination of glycine, magnesium, and thiamine can help people with primary ciliary dyskinesia (a condition that affects the tiny hairs in your lungs). It aims to see if these supplements improve breathing and reduce lung problems.
Mexico CityAges 5 years+ - NCT06955988RecruitingPhase 1
Safety and early results of AST2303 for advanced lung cancer
This trial tests a new oral drug, AST2303 (ABK3376), in people with advanced non-small cell lung cancer that has not responded to other treatments. It aims to see if the drug is safe and whether it can shrink tumors.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06956001RecruitingPhase 3
Testing firmanertinib vs chemo for first-line lung cancer with specific EGFR mutations
This trial compares a new targeted therapy pill (firmanertinib) to standard chemotherapy in people with advanced non-small cell lung cancer whose tumors have a specific EGFR mutation (PACC or L861Q). If you haven't had treatment for advanced disease and your cancer matches these mutations, this study may offer a more convenient oral option.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06952816Recruiting
Testing EMILY AI for respiratory failure
This study tests a new AI device (EMILY) that helps monitor breathing problems like acute respiratory failure. You may join if you are in a hospital for respiratory care and meet certain health criteria.
MadridAges 18 years+ - NCT06959095RecruitingPhase 3
Depemokimab for adults with COPD and type 2 inflammation
This trial tests a new biologic medicine called depemokimab, given as an injection, to see if it reduces flare-ups (exacerbations) in people with COPD who have a specific type of inflammation (high eosinophils). It may help if you have frequent flare-ups despite using your regular inhalers.
Bakersfield, CaliforniaAges 40–80 - NCT06956690RecruitingPhase 1/Phase 2
Testing HMBD-501 for HER3-positive advanced solid tumors
This trial tests a new drug, HMBD-501, for people with advanced solid tumors that have a specific protein called HER3. The goal is to see if the drug is safe and if it can help shrink or control the cancer.
La Jolla, CaliforniaAges 18 years+ - NCT06954246RecruitingPhase 3
New drug vs. doctor’s choice for relapsed small cell lung cancer
This trial tests a new drug called MHB088C for people with small cell lung cancer that has come back or gotten worse after standard treatments. It compares this drug to other options your doctor might choose. The goal is to see if MHB088C works better.
ShanghaiAges 18 years+ - NCT06953089RecruitingPhase 2
Combination therapy study for advanced solid tumors
This trial is testing two new drugs (DB-1311 with BNT327 or DB-1305) in people with certain advanced or metastatic solid tumors that have not responded to prior treatments. It aims to see if the combination shrinks tumors or slows cancer growth.
Los Angeles, CaliforniaAges 18 years+ - NCT06961214RecruitingPhase 3
Depemokimab for COPD with type 2 inflammation
This study tests a new biologic medicine, given as an injection, to see if it can reduce flare-ups in adults with COPD who have a certain type of inflammation. It may help people who still have frequent exacerbations despite using their current inhalers.
Sheffield, AlabamaAges 40–80 - NCT06546007Recruiting
Blood and tissue markers to detect lung cancer early
This study is testing whether certain markers in your blood or tissue can help find lung cancer early. It is for people who have lung cancer that can be removed by surgery and haven't had treatment yet.
RomaAges 35–85 - NCT06960382RecruitingPhase 1/Phase 2
Cat allergy immunotherapy with lymph node injections
This trial tests a new way to treat cat allergies by giving tiny injections directly into a lymph node (a part of your immune system), instead of under the skin. It aims to see if this method is safe and can reduce cat allergy symptoms, even in people with asthma.
ZurichAges 18–65 - NCT06960161RecruitingPhase 1
Light therapy to help with CPAP use
This trial tests if light therapy can help people who are having trouble tolerating their CPAP machine or who still snore while using it.
Edmonton, AlbertaAges 18 years+ - NCT06960291Recruiting
EXCEL Exercise Program for Cancer Patients in Canada
This study tests a national exercise program called EXCEL for people with cancer. It helps you start or continue safe physical activity to manage side effects and improve your well-being.
Calgary, AlbertaAges 18 years+ - NCT06958848Recruiting
Comparing two chest tube sizes after minimally invasive lung cancer surgery
This trial compares two sizes of chest tubes (16F and 24F) placed after minimally invasive lung cancer surgery. The goal is to see which size leads to better recovery and less pain, while still draining fluid and air effectively.
BaselAges 18 years+ - NCT06960200RecruitingPhase 2
Phototherapy for sleep apnea when a mouthpiece didn't work
This study tests a light-based treatment (phototherapy) for people with sleep apnea who tried an oral mouthpiece but still have symptoms. The goal is to see if this therapy can offer relief when other options haven't worked fully.
EdmontonAges 18 years+ - NCT06956911Enrolling by invitation
Low-resistance exercise with blood flow restriction after heart surgery
This trial tests if gentle arm exercises with a special blood pressure cuff can help men recover their lung function after heart surgery. It may be an option for those who are stable and ready to follow simple instructions.
Cairo, Cairo GovernorateAges 45–60 - NCT06956742Recruiting
Breathing device study for COPD shortness of breath after exercise
This trial tests a device that briefly opens your airways to help release trapped air after exercise. It may reduce shortness of breath and improve your daily life with COPD.
Rouen, NormandyAges 18 years+ - NCT06960759RecruitingPhase 2
Cough suppression therapy for chronic cough
This study tests a behavior-based therapy to help you gain control over a persistent cough that hasn't responded to other treatments. You will learn techniques to reduce coughing during a 4-week program.
Aurora, ColoradoAges 18–99 - NCT06956040Recruiting
Family doctor involvement in lung cancer screening
This study tests whether having your family doctor offer you a lung cancer screening scan (low-dose CT) can help find cancer early. You may qualify if you are a current or former heavy smoker and can travel to a Paris hospital for the scan.
ParisAges 50–74 - NCT06953804Recruiting
Better use of antibiotics in GP clinics
This study looks at how to improve the use of antibiotics (antimicrobial stewardship) in general practice clinics. It aims to find the best ways to help doctors prescribe antibiotics only when needed.
Wollongong, New South WalesAges 18 years+ - NCT06957314Recruiting
Hospital-at-home for people receiving Tarlatamab
This study tests giving hospital-type care at home for people with extensive-stage small cell lung cancer who are receiving the drug Tarlatamab. It aims to see if patients can safely receive their treatment at home instead of in the hospital.
Basking Ridge, New JerseyAges 18 years+ - NCT06958042Enrolling by invitation
Lung and bladder health study for COPD patients
This study looks at how common bladder problems are in people with stable COPD. It aims to help doctors better understand and manage these symptoms.
Kütahya, CenterAges 40–65 - NCT06958666Recruiting
Comparing two breathing exercises for COPD symptoms
This study compares two breathing exercise methods (DITM vs IMT) for people with COPD to see which helps improve symptoms and quality of life better. It's for people who are already using a specific type of inhaler.
Hangzhou, ZhejiangAges 40 years+ - NCT06954142Recruiting
Fluid levels to prevent lung disease in preterm babies
This trial compares giving less fluid versus the usual amount to very early preterm babies to see if it helps prevent bronchopulmonary dysplasia, a chronic lung condition. The goal is to find the safest way to manage fluids and protect their developing lungs.
AarauAges 1 week+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,352 recruiting pulmonology studies from the U.S. registry right now, out of 10,005 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.