Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,352 recruiting studies in this area right now.
By phase
- Not applicable4,048
- Phase 2834
- Phase 1460
- Phase 3421
- Phase 1/Phase 2312
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer416
- Asthma194
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD134
- Breast Cancer111
- Pulmonary Hypertension105
- Colorectal Cancer89
- COVID-1988
- NSCLC87
- Chronic Obstructive Pulmonary Disease84
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia68
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California385
- Alabama175
- Arizona154
- Florida121
- Massachusetts118
- Maryland115
- New York111
- Texas87
- Pennsylvania82
- Illinois73
Recruiting studies6,352 total
- NCT06962865RecruitingPhase 2
RC108 and Furmonertinib for first-line treatment of EGFR-mutated and MET-positive NSCLC
This trial tests whether a combination of two drugs, RC108 and Furmonertinib, can help people with non-small cell lung cancer (NSCLC) that has specific genetic changes (EGFR mutation and MET positivity) and cannot be removed by surgery. It is for people who have not yet received treatment for their advanced or metastatic cancer.
BeijingAges 18–75 - NCT06968377Recruiting
Device to reduce infection risk during breathing tube placement
This study tests a special device that may lower the risk of spreading germs when a breathing tube is placed during surgery. It is for healthy adults having planned surgery who are not at high risk for complications.
Halifax, Nova ScotiaAges 18 years+ - NCT06968962Recruiting
Starting PAH treatment: one drug first or two drugs together?
This study compares starting with one medication versus two medications together for people with pulmonary arterial hypertension (PAH). It aims to find out which approach works better for low- or intermediate-risk patients.
Hangzhou, ZhejiangAges 18–80 - NCT06969014Recruiting
Microwave ablation for lung tumors via bronchoscopy
This trial tests a minimally invasive procedure using microwave energy to destroy small lung tumors, guided by a thin tube through the airways. It may be an option if you can't have standard surgery or radiation, or choose not to.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06971042Recruiting
Using lung ultrasound to find ARDS early in ventilated patients
This study compares lung ultrasound with CT scans to detect ARDS (a serious lung injury) early in patients on a breathing machine. The goal is to see if ultrasound can provide a faster, safer way to diagnose ARDS.
TantaAges 22–80 - NCT06965322Recruiting
Detecting lung problems in rheumatoid arthritis
This study uses CT scans and blood tests to look for lung signs related to rheumatoid arthritis. It aims to find lung issues early, which may help in managing the disease better.
Innsbruck, AustriaAges 18 years+ - NCT06970080RecruitingPhase 4
Testing airway shape in adults with asthma
This trial uses advanced imaging to study the shape of airways in adults with asthma who have active symptoms and inflammation. It aims to find out if certain airway shapes affect how well treatments work, which could lead to more personalized asthma care.
Hamilton, OntarioAges 18 years+ - NCT06970171Enrolling by invitation
Willingness to use a sleep apnea mouthpiece
This trial tests how well people accept a mouthpiece (mandibular advancement device) to treat obstructive sleep apnea (a condition where your breathing stops and starts during sleep). If you have sleep apnea and can wear a device that moves your lower jaw forward while you sleep, you may be able to join.
Greifswald, Mecklenburg-VorpommernAges 18–75 - NCT06971874Recruiting
Sleep apnea and kidney disease: A study on outcomes
This trial looks at how obstructive sleep apnea affects people with chronic kidney disease (stages 3-4). It aims to help understand the connection between these conditions and guide better care.
Guangzhou, GuangdongAges 18–75 - NCT06962449Enrolling by invitation
Study of Tislelizumab as First Treatment for Advanced Lung Cancer
This study looks at how well Tislelizumab works as the first treatment for advanced non-small cell lung cancer that has spread. It aims to understand which treatment strategies after Tislelizumab lead to the best survival outcomes for patients.
Shanghai, Shanghai MunicipalityAges Any age - NCT06967324Recruiting
Tailored support for advanced COPD with flare-ups
This study tests a personalized care program for people with advanced COPD who have had a flare-up in the last year. It aims to improve quality of life and reduce symptoms by offering extra support at home.
HvidovreAges 65 years+ - NCT06963190Enrolling by invitation
Breathing Muscle Training After Lung Transplant
This study tests two types of breathing muscle training exercises in people who have had a lung transplant. The goal is to see which type helps you breathe better and improves your daily living.
Santander, CantabriaAges 18 years+ - NCT06967441Recruiting
Respiratory viruses and acute heart failure study
This trial looks at whether a respiratory virus might be triggering your heart failure. It will test your nasal swab for viruses to help doctors understand and treat your condition better.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT06966310Recruiting
Awake prone positioning for community acquired pneumonia with high-flow oxygen
This trial tests whether lying on your stomach (prone position) while awake can help people with pneumonia breathe better and avoid needing a breathing tube. It is for patients in the ICU or step-down unit who need high-flow oxygen therapy.
AmiensAges 18 years+ - NCT06962436Recruiting
Comparing Robotic vs. Ultrathin Bronchoscopy for Lung Nodules
This trial compares two types of bronchoscopy (thin-tube lung camera) methods to see which one better samples lung nodules. You may be able to join if you have a suspicious lung nodule and need a biopsy.
Jinan, ShandongAges 18 years+ - NCT06969443Recruiting
Studying rehab practices in the intensive care unit
This study watches how patients in the intensive care unit are helped to move and strengthen their muscles (rehabilitation) during their stay. It does not give any new treatment or medicine, but simply documents what usual care looks like for people who need a breathing tube for more than two days.
ParisAges 18 years+ - NCT06967896Recruiting
Comparing breathing tube types for women having thyroid surgery
This trial is testing different types of breathing tubes used during thyroid surgery in women. It aims to find which tube works best to keep the airway safe and reduce side effects.
Anqing, AnhuiAges 18–65 - NCT06966817Enrolling by invitation
Mouth care solutions for ventilator patients in the ICU
This study tests two different mouth-care solutions for patients on breathing machines, to see if they can prevent pneumonia and improve mouth health in intensive care.
AnkaraAges 18–90 - NCT03885245RecruitingPhase 2
L-citrulline supplement for overweight adults with later-onset asthma
This Phase 2 trial tests whether adding L-citrulline can improve asthma control in overweight adults whose asthma started later in life. It compares your asthma symptoms and lung testing results to see if the supplement helps when asthma is already being treated.
Durham, North CarolinaAges 18–65 - NCT03762395RecruitingPhase 2
Study of anti-inflammatory asthma molecules in adults
This Phase 2 study tests anti-inflammatory lipid mediators in people with asthma. You may be eligible if your asthma is not well controlled despite regular inhaler use and you meet the specific lung function and health criteria.
Aurora, ColoradoAges 18–65 - NCT06476015Recruiting
Exercise for chronic disease patients
This study looks at whether a physical exercise program can help people with long-term health conditions like COPD or diabetes. If you are 60 to 90 years old and already part of the 'Ser más' program, you may be able to join.
Medellín, AntioquiaAges 60–90 - NCT06754644RecruitingPhase 3
Study of QL2107 plus chemo vs. Keytruda for advanced lung cancer
This trial tests a new drug, QL2107, combined with chemotherapy, compared to the standard drug Keytruda (pembrolizumab) with chemotherapy. It is for people with stage IV non-squamous non-small cell lung cancer that does not have certain gene mutations (EGFR or ALK).
Jinan, ShandongAges 18–75 - NCT06850792Recruiting
Improving treatment adherence with telemedicine and guidance
This study tests whether regular remote check-ins and guidance can help people with pulmonary arterial hypertension stick to their treatment plan. You would be followed by phone or video from University of Sao Paulo.
São Paulo, São PauloAges 18 years+ - NCT06924398RecruitingPhase 2
Post-surgery targeted therapy for remaining lung nodules in EGFR-mutant NSCLC
This trial tests whether a targeted therapy pill (EGFR-TKI) can control small spots in the other lung after surgery for early-stage lung cancer. It's for people whose cancer has a specific EGFR gene change and who still have suspicious spots in the opposite lung after one side is removed.
Guangzhou, GuangdongAges 18–75
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,352 recruiting pulmonology studies from the U.S. registry right now, out of 10,005 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.