Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT06950073Recruiting
Second radiation treatment for lung cancer in the chest
This study tests whether giving a second course of radiation to the chest (called retreatment) can control lung cancer that has come back or a new cancer that started there. People who have already had radiation to their chest and are healthy enough for more may be eligible.
Aarhus, JutlandAges Any age - NCT06950294RecruitingEarly Phase 1
Inhaled nitric oxide for pneumonia patients on a ventilator
This study tests an inhaled gas (iNO300) given through your breathing tube to improve oxygen levels in critically ill patients with pneumonia. You may qualify if you are on a ventilator and have been diagnosed with pneumonia within the last 3 days.
Boston, MassachusettsAges 18 years+ - NCT06950515Recruiting
Anesthesia vs sedation for lung nodule biopsy
This trial compares general anesthesia with conscious sedation during a special ultrasound-guided lung biopsy. It aims to find which approach is safer and more comfortable for diagnosing small lung lesions.
Québec, QuebecAges 18 years+ - NCT06950697Recruiting
Blood clot risk prediction for lung cancer patients on immunotherapy
This study builds a tool to predict blood clot risk in lung cancer patients receiving immune checkpoint inhibitors. Researchers will use your data to develop a more personalized risk assessment, which may help prevent dangerous clots during treatment.
Zhengzhou, HenanAges 18 years+ - NCT06951464RecruitingPhase 2
Targeted therapy before surgery for EGFR-mutated lung cancer
This trial tests a combination of two targeted drugs (BL-B01D1 and almonertinib) given before surgery to shrink EGFR-mutated lung cancer. The goal is to make surgery more effective and possibly improve long-term outcomes.
Chengdu, SichuanAges 18–75 - NCT06951646RecruitingPhase 2
Personalized treatment for advanced lung cancer with long response to first-line therapy
This trial tests a combination of ivonescimab and docetaxel for people with advanced non-small cell lung cancer who have had a long response (11-15 months without the cancer getting worse) to first-line immunotherapy. The goal is to see if adjusting treatment based on ctDNA-MRD levels can improve outcomes.
ChangshaAges 18–75 - NCT06951633Recruiting
Salt mine rehab for older adults with breathing problems
This study tests if a special rehabilitation program in a salt mine can help people aged 65 and older who have chronic lung diseases breathe better and feel more energetic. The program includes exercises and time in a salt chamber, which may reduce inflammation and make breathing easier.
Wieliczka, WieliczkaAges 65 years+ - NCT06952816Recruiting
Testing EMILY AI for respiratory failure
This study tests a new AI device (EMILY) that helps monitor breathing problems like acute respiratory failure. You may join if you are in a hospital for respiratory care and meet certain health criteria.
MadridAges 18 years+ - NCT06952881Recruiting
Studying COPD types and treatable traits
This study looks at different forms of COPD to find better ways to treat them. It may help you understand your own condition and receive more personalized care.
Hong KongAges 40 years+ - NCT06953089RecruitingPhase 2
Combination therapy study for advanced solid tumors
This trial is testing two new drugs (DB-1311 with BNT327 or DB-1305) in people with certain advanced or metastatic solid tumors that have not responded to prior treatments. It aims to see if the combination shrinks tumors or slows cancer growth.
Los Angeles, CaliforniaAges 18 years+ - NCT06953414Recruiting
Predicting difficult awake breathing tube placement
This study tests a way to predict which patients will have a hard time placing a breathing tube while they are awake, using a flexible scope. It aims to help doctors plan safer procedures for people with known difficult airways.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT06953804Recruiting
Better use of antibiotics in GP clinics
This study looks at how to improve the use of antibiotics (antimicrobial stewardship) in general practice clinics. It aims to find the best ways to help doctors prescribe antibiotics only when needed.
Wollongong, New South WalesAges 18 years+ - NCT06954142Recruiting
Fluid levels to prevent lung disease in preterm babies
This trial compares giving less fluid versus the usual amount to very early preterm babies to see if it helps prevent bronchopulmonary dysplasia, a chronic lung condition. The goal is to find the safest way to manage fluids and protect their developing lungs.
AarauAges 1 week+ - NCT06954246RecruitingPhase 3
New drug vs. doctor’s choice for relapsed small cell lung cancer
This trial tests a new drug called MHB088C for people with small cell lung cancer that has come back or gotten worse after standard treatments. It compares this drug to other options your doctor might choose. The goal is to see if MHB088C works better.
ShanghaiAges 18 years+ - NCT06954727Recruiting
Study on first-time right heart catheterization for lung blood pressure
This study is watching people who are having their first right heart catheterization to better understand and manage lung blood pressure problems. It may help doctors improve diagnosis and treatment for people with shortness of breath or suspected pulmonary hypertension.
BeijingAges 14 years+ - NCT06955988RecruitingPhase 1
Safety and early results of AST2303 for advanced lung cancer
This trial tests a new oral drug, AST2303 (ABK3376), in people with advanced non-small cell lung cancer that has not responded to other treatments. It aims to see if the drug is safe and whether it can shrink tumors.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06956001RecruitingPhase 3
Testing firmanertinib vs chemo for first-line lung cancer with specific EGFR mutations
This trial compares a new targeted therapy pill (firmanertinib) to standard chemotherapy in people with advanced non-small cell lung cancer whose tumors have a specific EGFR mutation (PACC or L861Q). If you haven't had treatment for advanced disease and your cancer matches these mutations, this study may offer a more convenient oral option.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06956040Recruiting
Family doctor involvement in lung cancer screening
This study tests whether having your family doctor offer you a lung cancer screening scan (low-dose CT) can help find cancer early. You may qualify if you are a current or former heavy smoker and can travel to a Paris hospital for the scan.
ParisAges 50–74 - NCT06956690RecruitingPhase 1/Phase 2
Testing HMBD-501 for HER3-positive advanced solid tumors
This trial tests a new drug, HMBD-501, for people with advanced solid tumors that have a specific protein called HER3. The goal is to see if the drug is safe and if it can help shrink or control the cancer.
La Jolla, CaliforniaAges 18 years+ - NCT06956742Recruiting
Breathing device study for COPD shortness of breath after exercise
This trial tests a device that briefly opens your airways to help release trapped air after exercise. It may reduce shortness of breath and improve your daily life with COPD.
Rouen, NormandyAges 18 years+ - NCT06957314Recruiting
Hospital-at-home for people receiving Tarlatamab
This study tests giving hospital-type care at home for people with extensive-stage small cell lung cancer who are receiving the drug Tarlatamab. It aims to see if patients can safely receive their treatment at home instead of in the hospital.
Basking Ridge, New JerseyAges 18 years+ - NCT06958848Recruiting
Comparing two chest tube sizes after minimally invasive lung cancer surgery
This trial compares two sizes of chest tubes (16F and 24F) placed after minimally invasive lung cancer surgery. The goal is to see which size leads to better recovery and less pain, while still draining fluid and air effectively.
BaselAges 18 years+ - NCT06960200RecruitingPhase 2
Phototherapy for sleep apnea when a mouthpiece didn't work
This study tests a light-based treatment (phototherapy) for people with sleep apnea who tried an oral mouthpiece but still have symptoms. The goal is to see if this therapy can offer relief when other options haven't worked fully.
EdmontonAges 18 years+ - NCT06959095RecruitingPhase 3
Depemokimab for COPD with type 2 inflammation
This trial tests a new medicine, depemokimab, given as an injection to help reduce flare-ups (exacerbations) in adults with moderate to severe COPD who have a certain type of inflammation. The goal is to see if it can keep you healthier for longer with fewer serious breathing attacks.
Loxahatchee Groves, FloridaAges 40–80
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.