Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,643 recruiting studies in this area right now.
By phase
- Not applicable4,313
- Phase 2851
- Phase 1471
- Phase 3424
- Phase 1/Phase 2309
- Phase 4209
- Phase 2/Phase 366
Top conditions
- Lung Cancer425
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD142
- Breast Cancer111
- COVID-19107
- Pulmonary Hypertension101
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Interstitial Lung Disease79
- Pneumonia79
- Cystic Fibrosis78
- Chronic Obstructive Pulmonary Disease (COPD)73
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca64
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona155
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas91
- Pennsylvania82
- Illinois72
Recruiting studies6,643 total
- NCT00081523Recruiting
Understanding How Sickle Cell Disease Develops Over Time
This research study follows people with sickle cell disease to learn how the condition affects their health over many years. By studying patients regularly, researchers hope to better understand the disease and improve care.
Washington D.C., District of ColumbiaAges 2–90 - NCT00001532Recruiting
How Genes Affect Lung Disease Development
This research study examines how genetic factors contribute to various lung diseases, including alpha-1 antitrypsin deficiency, cystic fibrosis, and chronic obstructive pulmonary disease. Researchers want to understand why some people develop lung disease and how genetics plays a role, which may help improve treatment in the future.
Bethesda, MarylandAges 2–90 - NCT00128973Recruiting
Study immune system problems in people with unusual infections
This study looks at how the immune system works in people who have abnormal immune function, often shown by unusual or repeated infections or long-lasting inflammation. It may involve tests using blood samples and storage of blood for future research.
Bethesda, MarylandAges Any age - NCT00900419Recruiting
Check biomarkers during bronchoscopy in breathing and throat pre-cancer
This study looks at “biomarkers” (measurable signals in samples) taken during bronchoscopy or related procedures in people with severe airway pre-cancer or certain lung/throat cancers, and in healthy volunteers. The goal is to better understand what these biomarkers mean and how they might help with diagnosis, staging, or monitoring.
Aurora, ColoradoAges 21–90 - NCT00901602Recruiting
Study of invasive pneumococcal infections in Lebanon
This study collects laboratory samples from patients with invasive pneumococcal infections to learn about the germ and where it spreads. It may help doctors and public health teams track infection patterns and improve prevention and treatment planning.
BeirutAges 1 day+ - NCT01804686RecruitingPhase 3
Long-term ibrutinib follow-up with or without nivolumab
This study looks at how safe and effective ibrutinib is over the long term, either alone or together with nivolumab. You may join if you are already in an earlier ibrutinib study and your care team feels staying on ibrutinib is worth the risk.
Duarte, CaliforniaAges 18 years+ - NCT01789229Recruiting
Tumor and inflammation sample bank for one specific condition
This study builds a secure “tumor sample bank” using tissue collected from people who currently have one diagnosed condition, either cancer (malignant disease) or an ongoing inflammatory condition. Your samples could help researchers study your disease and develop better treatments in the future.
ViennaAges 18 years+ - NCT01763125Recruiting
Tumor bank trial for storing your blood sample
This study sets up a “tumor bank,” which means storing and later using your blood sample for future cancer research (or inflammatory disease research). You may be able to join if you currently have exactly one diagnosis—either a cancer or an inflammation condition.
InnsbruckAges 18 years+ - NCT00077909Recruiting
Study of Lung Proteins in Patients With Pneumonia
This research study examines proteins in fluid collected from your lungs during a breathing tube procedure (bronchoscopy) to better understand pneumonia. By studying these proteins, researchers hope to improve how doctors diagnose and treat lung infections.
Bethesda, MarylandAges 3–99 - NCT00451022Recruiting
Follow-up study for people who received gene-carrying viral vaccines
This is a follow-up study for adults who previously received certain viral vaccines that carry genes (such as vaccinia or fowlpox) through NCI trials or partner sites. The goal is to store and use your leftover samples for future research that may help doctors understand these treatments better.
Bethesda, MarylandAges 18 years+ - NCT00001823Recruiting
Surgery Branch Screening for Cancer Treatment Studies
This is a screening evaluation to see if you might be eligible for cancer treatment research studies at the National Cancer Institute's Surgery Branch. Doctors will review your medical history, imaging, and test results to determine which clinical trials might be right for you.
Bethesda, MarylandAges 18 years+ - NCT01441089Recruiting
Donate blood for genetic testing in an NIH research study
This study collects blood from people already in an NIH (National Institutes of Health) clinical research program to run genetic tests. It may help researchers understand cancer and related inherited conditions by studying DNA changes.
Bethesda, MarylandAges 3 years+ - NCT00307281Recruiting
Emphysema and COPD patient registry with sample storage
This study enrolls people who have emphysema/COPD into a research registry and collects health information and biological samples. It may help researchers understand the disease better and improve future treatments.
Pittsburgh, PennsylvaniaAges 21 years+ - NCT00280202Recruiting
Find lung cancer genetic markers from tissue samples
This study looks for specific genetic markers of lung cancer by testing tissue taken from a lung mass. It may help doctors detect and better understand lung cancer based on genetic clues.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT00682032Recruiting
Beta-glucan for non-small cell lung cancer
This study tests whether beta-glucan, a supplement taken by mouth, can help people with non-small cell lung cancer. You may be able to join if you’re newly diagnosed (no recent treatment) and can safely take pills.
Louisville, KentuckyAges 18 years+ - NCT01068990Recruiting
Testing how to identify pneumonia germs in ICU patients
This study looks at how well doctors can detect and identify the cause of new pneumonia in people in the medical intensive care unit (ICU). It may help improve how pneumonia is diagnosed and treated in critically ill patients.
SeoulAges 16 years+ - NCT00576069Recruiting
Study airflow limits in moderate asthma
This trial looks at why airflow is limited in people with moderate-to-severe persistent asthma who are already on stable treatment. It may help researchers better understand what drives breathing trouble and how to target it.
Lakewood, CaliforniaAges 10–95 - NCT00898313Recruiting
Study looks for cancer clues in people at high risk for lung cancer
This study enrolls adults who are being checked for possible lung cancer because of concerning symptoms or a high-risk situation. It aims to find molecular (cell/DNA-related) predictors that may help doctors better recognize lung cancer earlier.
Nashville, TennesseeAges 18 years+ - NCT00897117Recruiting
Providing tumor tissue samples during lung cancer surgery
This study collects and analyzes tumor tissue from people with early-stage non-small cell lung cancer who are planning surgery. It may help researchers learn more about the cancer by studying samples taken at the time of your operation.
Nashville, TennesseeAges 18–120 - NCT00470327Recruiting
Study of how interstitial lung disease naturally changes
This study looks at how interstitial lung disease (lung scarring) typically progresses over time. It may help researchers understand what to expect and what changes to watch for.
Chicago, IllinoisAges 18 years+ - NCT02061787Recruiting
Exercise testing to assess outcomes in pulmonary hypertension
This trial studies how well a treadmill/breathing exercise test can measure health outcomes in people with certain types of pulmonary hypertension. It may help your care team judge your status and track changes over time.
BeijingAges 5–100 - NCT01501838Recruiting
Registry study for adults with a specific type of pulmonary hypertension
This study is a hospital registry that collects information about adults diagnosed with pulmonary arterial hypertension (a specific type of high blood pressure in the lungs). It helps doctors better understand patients over time and improve care.
Buenos Aires, Buenos AiresAges 17 years+ - NCT00710177Recruiting
Study genes and risk of persistent lung blood pressure in newborns
This study looks at a newborn’s genes (PTGS1 variation) and whether that relates to persistent pulmonary hypertension of the newborn (PPHN), a serious breathing/lung blood-pressure problem. It may help doctors understand who is at higher risk and how to better identify affected babies early.
Milwaukee, WisconsinAges Up to 1 year - NCT02095808Recruiting
Testing blood and body markers in lung and chest cancers
This study looks at “biomarkers,” which are measurable signs in the body (often in blood or samples), in people with lung or other chest cancers. It may help researchers better understand these cancers and improve how they’re diagnosed or tracked.
Dallas, TexasAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,643 recruiting pulmonology studies from the U.S. registry right now, out of 10,656 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.