Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,643 recruiting studies in this area right now.
By phase
- Not applicable4,313
- Phase 2851
- Phase 1471
- Phase 3424
- Phase 1/Phase 2309
- Phase 4209
- Phase 2/Phase 366
Top conditions
- Lung Cancer425
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD142
- Breast Cancer111
- COVID-19107
- Pulmonary Hypertension101
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Interstitial Lung Disease79
- Pneumonia79
- Cystic Fibrosis78
- Chronic Obstructive Pulmonary Disease (COPD)73
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca64
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona155
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas91
- Pennsylvania82
- Illinois72
Recruiting studies6,643 total
- NCT01803542RecruitingPhase 2
Stereotactic radiation for lung metastases or early lung tumors
This trial studies a precise, high-dose radiation technique (SBRT) to treat tumors in the lungs. It may help control cancer in people who either have early-stage lung cancer that is not fully operable or have limited lung metastases from other cancers.
Toronto, OntarioAges 18 years+ - NCT00033137Recruiting
Genetic study of Birt-Hogg-Dubé syndrome and kidney cancer risk
This research study examines the genes behind Birt-Hogg-Dubé (BHD) syndrome, a condition that increases kidney cancer risk. Researchers want to understand who inherits this condition and how to better identify and help people at risk.
Bethesda, MarylandAges 2 years+ - NCT00034216Recruiting
Blood Collection Study for Cancer Patients and Healthy Volunteers
This study collects blood samples from people with cancer and healthy volunteers to help researchers understand cancer better. Your blood will be used for laboratory studies that may improve future cancer treatments.
Bethesda, MarylandAges 18 years+ - NCT02057783Recruiting
Exercise program to lower blood pressure in sleep apnea
This trial tests whether a supervised physical activity program can help lower blood pressure in people with obstructive sleep apnea and resistant high blood pressure. It may help you control blood pressure when it has not improved despite multiple medications.
QuébecAges 18–80 - NCT01786590Recruiting
Ultrasound biopsy to stage lung cancer before SBRT
This trial looks at using a scope with an ultrasound tip (EBUS-TBNA) to take small tissue samples from lymph nodes to figure out the cancer stage before stereotactic body radiotherapy (SBRT). The goal is to help confirm how far the cancer has spread so SBRT can be planned appropriately.
Toronto, OntarioAges 18 years+ - NCT01225913RecruitingPhase 4
Testing airflow limits in asthma flare-ups
This Phase 4 study looks at what causes breathing airways to narrow during asthma worsening, in people with stable, treated asthma. It may help improve how clinicians understand and manage asthma flare-ups.
Lakewood, CaliforniaAges 10–80 - NCT00722228RecruitingPhase 1/Phase 2
Cancer vaccine made from your cells or a donor
This early-phase trial tests a whole-cell cancer vaccine for people with certain metastatic cancers. It aims to help your immune system recognize and fight the cancer, especially when prior chemotherapy hasn’t worked.
JerusalemAges 18 years+ - NCT00943514Recruiting
Study of bronchiectasis and why infections keep coming back
This study follows children (age 5+) and adults with bronchiectasis or ongoing/repeated lung infections to learn what makes infections more likely. It mainly looks at non–cystic fibrosis causes, but may include some related conditions to compare differences.
Bethesda, MarylandAges 5–100 - NCT01607502Recruiting
Database study for people with pulmonary hypertension symptoms
This study builds a medical and symptom database for people who have pulmonary hypertension or may be at risk, to better understand the condition. If you choose to participate, your basic health information and symptom history may be recorded and used for research.
GrazAges 18 years+ - NCT00301119Recruiting
Lung cancer screening using risk factors and test results
This study looks at how to find lung cancer earlier by screening people based on their lung-cancer risk. It may help doctors decide who needs further testing if lung nodules are found.
New York, New YorkAges 50 years+ - NCT00341237Recruiting
Study linking genes and environment to health risks
This study looks at how your genes and your environment may affect your health. It may help researchers better understand who is most at risk so future prevention and care can be more personalized.
Chapel Hill, North CarolinaAges 18–120 - NCT01712620RecruitingPhase 2
Spironolactone for pulmonary arterial hypertension in stable patients
This trial studies whether spironolactone can improve pulmonary arterial hypertension, a disease that makes the blood vessels in the lungs work too hard. You may be eligible if your condition is confirmed by specific heart-lung pressure tests and your medication plan has been stable for at least 4 weeks.
Bethesda, MarylandAges 18–100 - NCT00471250Recruiting
Donate lung samples to help future lung and airway research
This study collects lung fluid and tissue (and sometimes nasal or breath samples) to store for future research. It aims to understand lung and airway biology, and you may help by donating samples during a short procedure.
Bethesda, MarylandAges 5–100 - NCT01852448Recruiting
Study genes affecting insulin in people with cystic fibrosis
This study looks at how genes may affect insulin and “incretin” hormones in people with cystic fibrosis. It may help researchers understand why some people develop blood-sugar problems and how to predict or prevent them.
Philadelphia, PennsylvaniaAges 2 years+ - NCT00500123Recruiting
Alpha-1 genetic and blood testing for people at risk
This study checks whether doing alpha-1 screening (genetic test and a blood level test) can help identify alpha-1 antitrypsin deficiency in people at risk. It may be useful if you have symptoms or a family history, but you haven’t had qualifying testing yet.
Gainesville, FloridaAges Any age - NCT00515567Recruiting
Study lung tissue from people with lung scarring
This study uses lung tissue removed during lung transplant to learn more about lung scarring (pulmonary fibrosis). It can help researchers understand the disease better and improve future treatments.
Chicago, IllinoisAges 18 years+ - NCT01929356Recruiting
Breathing therapy test for primary ciliary dyskinesia
This study looks at how chest physiotherapy affects lung function in people with primary ciliary dyskinesia (a lifelong condition affecting mucus movement in the lungs). It may help care teams understand which breathing therapies work best and how your lungs respond.
LeuvenAges 6–50 - NCT02038166Recruiting
Measuring nasal function in adults with chronic sinus symptoms
This study tests a specialized way of measuring how your nasal lining responds in people with chronic rhinosinusitis (long-lasting sinus inflammation). The goal is to see whether the nasal measurement is usable and safe, and to help better understand chronic sinus disease.
Birmingham, AlabamaAges 18 years+ - NCT00595491RecruitingPhase 1
Study immune targets in cat and dust-mite allergic airway inflammation
This Phase 1 study looks at how the immune system drives allergic airway inflammation in people with allergic asthma, and compares them with allergic non-asthma and non-allergic healthy volunteers. The goal is to identify immune “signals” and cell “receptors” involved, which may guide better future treatments.
Boston, MassachusettsAges 18–50 - NCT01720836RecruitingPhase 1/Phase 2
MUC1 peptide vaccine study for non-small cell lung cancer
This trial tests a vaccine made from a lung-cancer target (MUC1) to help your immune system recognize and fight the cancer. It is designed to measure immune response and safety, and it may help some people develop a stronger anti-cancer immune reaction.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT01730092Recruiting
Study of blood and imaging biomarkers in pulmonary artery hypertension
This study tracks natural changes in “biomarkers” (measurable signals in blood) and imaging findings in people with pulmonary arterial hypertension (PAH) or suspected PAH. It also includes healthy people for comparison, helping researchers understand what these signals mean over time.
Bethesda, MarylandAges 18–100 - NCT01851694Recruiting
Study incretin hormone response in adults with cystic fibrosis
This study tests how the body’s “incretin” hormones affect insulin (sugar control) in adults with cystic fibrosis and certain blood sugar patterns. It may help explain what drives diabetes risk in cystic fibrosis and how the body responds to these hormone signals.
Philadelphia, PennsylvaniaAges 18 years+ - NCT01851642Recruiting
Study how lung disease affects white blood cells
This study looks at how lung disease changes a type of blood cell called white blood cells. It may help researchers understand what’s happening in the lungs and how to better monitor or treat lung problems.
Gainesville, FloridaAges 18 years+ - NCT01143480Recruiting
Testing how the body responds to endotoxin
This study checks how your immune system (your body’s defense system) reacts to a controlled substance that triggers inflammation. It may help researchers understand why some people have stronger or weaker inflammatory responses.
Research Triangle Park, North CarolinaAges 18–100
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,643 recruiting pulmonology studies from the U.S. registry right now, out of 10,656 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.