Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,618 recruiting studies in this area right now.
By phase
- Not applicable4,293
- Phase 2848
- Phase 1470
- Phase 3423
- Phase 1/Phase 2310
- Phase 4207
- Phase 2/Phase 367
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer179
- Non-small Cell Lung Cancer171
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer109
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Pneumonia78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Riphah International University34
Where studies are running
- California389
- Alabama174
- Arizona154
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas89
- Pennsylvania84
- Colorado71
Recruiting studies6,618 total
- NCT06757166Recruiting
Non-invasive respiratory support for COVID-19 breathing failure
This study tests if non-invasive breathing support (like a mask or high-flow oxygen) can help hospitalized patients with low oxygen levels due to COVID-19, without needing a breathing tube. It aims to see how well it works and what risks it may have.
Rotterdam, South HollandAges 18 years+ - NCT07722260Recruiting
Cough assistance for breathing tube weaning
This study tests whether special cough-aid techniques help adults on breathing tubes get off the ventilator faster. It may be an option for patients who need extra help coughing while they recover.
DamanhūrAges 18 years+ - NCT06439901Recruiting
Improving lung cancer screening in Ile-de-France
This trial tests a new way to screen for lung cancer in people at high risk due to smoking. If you are between 50 and 74, live in the Ile-de-France region, and have a long smoking history, you may be able to join and get a free screening.
BobignyAges 50–74 - NCT06093152Recruiting
Salbutamol for viral wheezing in children
This study uses video recordings to see how well salbutamol helps children with wheezing caused by a virus. Researchers want to understand when this medicine works best.
OuluAges 6 months–2 years - NCT06008730RecruitingPhase 2
Proton beam radiation after lung cancer surgery
This trial tests if proton beam radiation therapy is safe and effective after surgery for non-small cell lung cancer that has spread to lymph nodes in the chest. It is for people who have already had chemotherapy before their surgery.
Atlanta, GeorgiaAges 18 years+ - NCT06306456RecruitingPhase 1/Phase 2
GH21 combined with osimertinib for advanced lung cancer
This trial tests a new drug (GH21) combined with the targeted therapy osimertinib (Tagrisso) for people with advanced non-small cell lung cancer that has an EGFR mutation and has stopped responding to a similar treatment. The goal is to see if the combination can help when the cancer has progressed.
Hefei, AnhuiAges 18 years+ - NCT06030258RecruitingPhase 1/Phase 2
Study of IN10018 plus standard chemo for extensive-stage small cell lung cancer
This trial tests a new drug called IN10018 combined with standard chemotherapy (carboplatin and etoposide) and an immunotherapy (anti-PD-1/L1) for people with extensive-stage small cell lung cancer (ES-SCLC) who have not yet been treated. The goal is to see if adding IN10018 helps shrink tumors or slow the cancer's growth.
JinanAges 18–75 - NCT05745350RecruitingPhase 2
First treatment for extensive-stage small cell lung cancer
This trial studies how well pembrolizumab, plinabulin, and etoposide plus platinum work as first treatment for extensive-stage small cell lung cancer. It may help some people by boosting the immune response while also attacking cancer with standard chemotherapy.
Wuhan, HubeiAges 18 years+ - NCT07709494RecruitingPhase 1
Inhaled Rev-56 for healthy volunteers and people with bronchiectasis
This trial tests an inhaled drug called Rev-56 in healthy adults and in adults with non-cystic fibrosis bronchiectasis who have a chronic lung infection with Pseudomonas aeruginosa. It aims to see if the drug is safe, well-tolerated, and helps reduce the bacteria in the lungs.
Miami, FloridaAges 18–80 - NCT07284485RecruitingPhase 2
Preventing lung cancer in people with high-risk lung spots
This trial tests an immunotherapy approach to stop high-risk lung spots from turning into cancer. It is for people who are current or former heavy smokers with multiple slow-growing lung nodules that are not yet ready for surgery.
New York, New YorkAges 18 years+ - NCT07706309Recruiting
Comparing two ways to replace a breathing tube
This trial compares two methods for exchanging a breathing tube: using a bronchoscope (a thin camera) versus a special guide called an airway exchange catheter. It is conducted on Thiel-embalmed body donors to find the safest and most effective way to replace a breathing tube.
BaselAges 18 years+ - NCT07704320Recruiting
Testing the BreathAlert device for apnea monitoring
This trial tests a device called BreathAlert that monitors breathing and detects when a patient stops breathing (apnea). It aims to help doctors and nurses keep a closer watch on patients who are at risk.
BlantyreAges birth–17 years - NCT05778708Recruiting
Tai Chi and aerobic exercise for mood and sleep in late lung cancer
This study tests whether Tai Chi and aerobic exercise can improve clusters of emotional symptoms—like anxiety, low mood, poor sleep, and fatigue—in people with late-stage non-small cell lung cancer. If you have these symptoms and are not already doing regular exercise programs, the trial may offer a structured way to feel better.
Hong KongAges 18 years+ - NCT06763536Recruiting
Comparing nicotine pouches vs. nicotine patches or gum to help smokers in rural Appalachia quit
This study tests if oral nicotine pouches work better than nicotine patches or gum to help you smoke less. You’ll use one of these products for a while and check in with the study team. This is for adults who live in rural Appalachian counties and smoke at least 5 cigarettes a day.
Columbus, OhioAges 21 years+ - NCT07528066Recruiting
Surgery After Chemotherapy and Immunotherapy for Advanced Lung Cancer
This study follows patients with advanced non-small cell lung cancer (NSCLC) who receive combination chemotherapy and immunotherapy before surgery. Researchers will track how well surgery works after this pre-surgical treatment and compare different surgical approaches.
Fuzhou, FujianAges Any age - NCT07698769Recruiting
Nirsevimab study for infants with RSV bronchiolitis
This trial looks at how well the drug nirsevimab works for babies hospitalized with RSV bronchiolitis. It also studies the body's immune response and the baby's environment. The goal is to see if nirsevimab can help infants recover from this serious lung infection.
CréteilAges birth–6 months - NCT06459011Recruiting
TAKINGCARE: Helping caregivers of lung disease patients
This study aims to understand the needs of people with long-term lung diseases and their caregivers. The goal is to find ways to better support both patients and the family members who help care for them.
AveiroAges 18 years+ - NCT06714708RecruitingPhase 2
Low-dose radiation with immunotherapy and chemo before surgery for lung cancer
This trial tests a combination of low-dose radiation, an immunotherapy drug called sintilimab, and standard chemotherapy before surgery for stage II–III non-small cell lung cancer (NSCLC). The goal is to see if this approach can shrink tumors and improve outcomes for patients who are candidates for surgery.
Hefei, AnhuiAges 18 years+ - NCT06766136Recruiting
Asthma education program based on the Roy Adaptation Model
This trial tests a new asthma education program designed to help you better manage your asthma symptoms and improve your quality of life. The program is based on the Roy Adaptation Model, which focuses on helping you adapt to your condition.
Niğde, CenterAges 18–64 - NCT06655805Recruiting
Registry for automated breathing support in adults
This trial collects data from adults in the ICU who need oxygen therapy, non-invasive ventilation, or a breathing tube with a machine. It looks at how automated settings affect care.
Sankt Gallen, Canton of St. GallenAges 18 years+ - NCT07683728Recruiting
Observational study of progressive pulmonary fibrosis (PPF) in China
This study is a registry that collects information from people in China who have progressive pulmonary fibrosis (PPF), a lung condition that gets worse over time. It aims to better understand the disease and help doctors improve care.
BeijingAges Any age - NCT06707623Recruiting
Comparing rehab therapy vs physiotherapy for dysfunctional breathing
This trial compares two different types of therapy for people with dysfunctional breathing: a rehab program guided by a special exercise test (CPET) versus standard physiotherapy. The goal is to see which approach helps your breathing feel better.
Athens, AtticaAges 18 years+ - NCT06986993RecruitingPhase 4
Semaglutide for smoking and weight in people with obesity
This study tests whether the medication semaglutide (similar to Ozempic/Wegovy) can help people who smoke and have obesity cut down on cigarettes, even if they aren't ready to quit. Participants will receive the drug and be monitored for changes in smoking habits and health.
Oklahoma City, OklahomaAges 18–65 - NCT07525427RecruitingPhase 2
New Tuberculosis Drug Study for Drug-Sensitive TB
This study tests a new tuberculosis drug called TBD09 combined with other TB medicines in people with newly diagnosed, drug-sensitive TB. The goal is to see if this combination works well and is safe.
Durban, BluffAges 18–65
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,618 recruiting pulmonology studies from the U.S. registry right now, out of 10,521 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.