Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,618 recruiting studies in this area right now.
By phase
- Not applicable4,293
- Phase 2848
- Phase 1470
- Phase 3423
- Phase 1/Phase 2310
- Phase 4207
- Phase 2/Phase 367
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer179
- Non-small Cell Lung Cancer171
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer109
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Pneumonia78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Riphah International University34
Where studies are running
- California389
- Alabama174
- Arizona154
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas89
- Pennsylvania84
- Colorado71
Recruiting studies6,618 total
- NCT05678530Recruiting
Study uses routine exercise test to check fitness measuring methods
This observational study does not change your treatment. It collects results from your usual cardiopulmonary exercise test (CPET) to help validate better ways to estimate VO2max, a measure of exercise capacity.
Scottsdale, ArizonaAges 18 years+ - NCT07710820Recruiting
Can a heated tobacco product help you stop smoking?
This study tests whether having access to a heated tobacco product (a device that heats tobacco, not burns it) helps current cigarette smokers quit smoking. You'll try four different flavors over a week and then continue using one you like.
Brandon, FloridaAges 21–65 - NCT06297005Recruiting
E-cigarette use in pregnancy and child health study
This study looks at how using e-cigarettes during pregnancy might affect children's health. If you are pregnant, smoke or vape, or are a non-smoker, you may be able to join and help us learn more.
DublinAges 18–46 - NCT05456009Recruiting
Breath analysis test for adults
This study tests how analyzing your breath can help researchers detect or understand health conditions. If you’re an adult and can safely participate, you may be able to take part and have your exhaled breath measured.
Zurich, Canton of ZurichAges 18 years+ - NCT07519733Recruiting
Exercise Testing Before High-Risk Surgery
This study tests whether a simple exercise test before surgery can help doctors better predict and prevent complications in older adults undergoing major operations. You'll do a gentle exercise test on a stationary bike or treadmill to measure your fitness level.
New Haven, ConnecticutAges 45 years+ - NCT07184801RecruitingPhase 3
Comparing two sedatives for medical thoracoscopy
This trial tests if dexmedetomidate or midazolam is safer and works better for sedation during a medical thoracoscopy, a procedure to look inside the chest. It may help you if you need this procedure for an unclear pleural effusion.
Chandigarh, ChandigarhAges 12–90 - NCT07672548Recruiting
Pilates for better breathing and quality of life in postmenopausal women
This 10-week study tests whether Pilates exercises can improve lung function and overall well-being in postmenopausal women who have breathing problems. It may help you feel stronger and breathe easier.
AmmanAges 50–60 - NCT06033196RecruitingPhase 2
Tocilizumab to prevent lung transplant rejection
This trial tests a drug called tocilizumab (brand name Actemra) to see if it helps prevent rejection after lung transplantation. Tocilizumab targets part of the immune system that may otherwise attack the new lungs.
Phoenix, ArizonaAges 12–75 - NCT05886803Recruiting
Predicting breathing test success in the ICU
This study uses data from your hospital records to see if a machine learning tool can predict whether a patient will succeed when doctors try to remove their breathing tube during a test of their own breathing.
NiceAges Any age - NCT06153485Enrolling by invitation
Automated oxygen adjustment for home therapy
This trial is testing a smart system that automatically adjusts your home oxygen levels based on your needs. It's designed for people with stable lung conditions who already use home oxygen therapy.
Toronto, OntarioAges 18 years+ - NCT06686693RecruitingPhase 4
IV iron and exercise at high altitude
This study tests whether giving iron through a vein helps you perform better at high altitude. It may help you if you are a healthy adult who exercises regularly.
Natick, MassachusettsAges 18–40 - NCT07516379Recruiting
Understanding Lung Rejection After Transplant
This study follows people with serious lung disease before and after lung transplant to understand how rejection happens and what warning signs to watch for. By studying your blood, tissue samples, and imaging, researchers hope to better predict and prevent transplant rejection.
Bethesda, MarylandAges 18–75 - NCT07519512Recruiting
Early Switch to Assisted Breathing in ICU Patients
This study tests whether moving ICU patients from fully machine-controlled breathing to partially assisted breathing earlier helps them get off ventilators successfully. The goal is to see if this approach reduces the time patients need mechanical ventilation.
Nanjing, JiangsuAges 18 years+ - NCT06768151RecruitingPhase 1
CEA-targeting car-t therapy for advanced lung cancer
This trial tests a new treatment called CAR-T therapy that targets a protein called CEA found on some lung cancer cells. It is for people with advanced lung cancer that has not responded to or has gotten worse after at least two standard treatments.
Wuhan, HubeiAges 18 years+ - NCT07492420Recruiting
Sleep position therapy for mild sleep apnea
This study tests if a special sleep system that keeps you on your side can improve mild obstructive sleep apnea. You may qualify if you have mild sleep apnea and are looking for a non-surgical treatment option.
St Louis, MissouriAges 18 years+ - NCT07048262RecruitingPhase 2
Study of an inhaled drug for adults with non-CF bronchiectasis
This trial tests an inhaled medication called CSL787 to see if it can help people with non-cystic fibrosis bronchiectasis (a lung condition that causes frequent infections and breathing problems). The study looks at different doses and checks how well the drug works and if it is safe.
QueenslandAges 18–85 - NCT07505914Recruiting
Breathing exercises for better thinking in older adults
This trial tests whether simple breathing exercises can improve memory and thinking skills in adults aged 65 and older. You would attend two sessions each week for 8 weeks.
IstanbulAges 65 years+ - NCT06855004Recruiting
Study of severe breathing problems in people with lung scarring
This study follows patients with chronic lung scarring (fibrosing interstitial lung disease) who are in the intensive care unit for severe breathing failure. It aims to better understand their condition and care, which may help improve future treatments.
BobignyAges 18 years+ - NCT06474299RecruitingPhase 4
Quit Smoking and Vaping With Patches and Pills
This study tests whether a combination of a nicotine patch plus a medication called varenicline can help people who both smoke and vape quit both. You'll get free medication and support to help you stop.
Madison, WisconsinAges 21 years+ - NCT06668103RecruitingPhase 2
Study of ABSK043 and Firmonertinib for EGFR-mutant lung cancer
This study tests a new combination of two targeted therapies (ABSK043 and firmonertinib) for people with a specific type of advanced lung cancer. It is for patients whose tumors have an EGFR mutation and are PD-L1 positive.
Hefei, AnhuiAges 18 years+ - NCT07492342RecruitingPhase 2
Fulzerasib with immunotherapy and chemo before surgery for KRAS G12C lung cancer
This trial tests a combination of a targeted pill (Fulzerasib) and immunotherapy (Sintilimab) plus standard chemotherapy before surgery, for people with early-stage non-small cell lung cancer that has a specific KRAS G12C mutation. The goal is to shrink the tumor and make surgery more effective.
BeijingAges 18 years+ - NCT07190079Recruiting
New way to diagnose blood clots in the lungs using saline
This study tests a new method using a saline solution and a special imaging belt to quickly diagnose pulmonary embolism (a blood clot in the lungs) in people with acute breathing problems. If successful, it could provide a faster, safer alternative to standard CT scans.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05745298Recruiting
Electrical and breathing therapy to improve unassisted cough after spinal injury
This study tests whether pairing electrical stimulation with breathing muscle training can help you cough without needing assistance. It’s for people recovering from a spinal cord injury within the last year, and who can safely feel and respond to the electrical stimulation.
Miami, FloridaAges 18 years+ - NCT07190677Recruiting
Nivolumab plus ipilimumab with chemo for advanced lung cancer
This trial tests combining two immunotherapy drugs (nivolumab and ipilimumab) with chemotherapy as a first treatment for advanced lung cancer that has spread or come back. It may help if your cancer hasn't been treated before and doesn't have certain genetic changes.
Pavia, LombardyAges Any age
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,618 recruiting pulmonology studies from the U.S. registry right now, out of 10,521 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.