Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,618 recruiting studies in this area right now.
By phase
- Not applicable4,293
- Phase 2848
- Phase 1470
- Phase 3423
- Phase 1/Phase 2310
- Phase 4207
- Phase 2/Phase 367
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer179
- Non-small Cell Lung Cancer171
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer109
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Pneumonia78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Riphah International University34
Where studies are running
- California389
- Alabama174
- Arizona154
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas89
- Pennsylvania84
- Colorado71
Recruiting studies6,618 total
- NCT06384885Recruiting
Ultrasound for swimming lung fluid in open water athletes
This study uses ultrasound to check for fluid buildup in the lungs (swimming-induced pulmonary edema) in athletes who swim in open water races. It helps doctors understand how common this condition is and how to spot it quickly.
Parker, ColoradoAges 18 years+ - NCT06735391RecruitingPhase 3
JMT101 plus osimertinib vs osimertinib for EGFR-mutant lung cancer
This trial tests a new combination of two targeted drugs (JMT101 and osimertinib) against osimertinib alone for people with advanced lung cancer that has an EGFR mutation. The goal is to see if the combination works better as a first treatment.
GuangzhouAges 18 years+ - NCT07084402RecruitingPhase 4
Effect of Contezolid on MAC lung disease
This trial tests whether the drug Contezolid can quickly kill the bacteria that cause MAC lung disease, a type of lung infection. It is for people who have not been treated for this infection in the last 3 months.
Beijing, Beijing MunicipalityAges 18–75 - NCT07372287RecruitingPhase 3
Study of CM326 for moderate to severe asthma
This trial tests an investigational drug called CM326 for people with moderate to severe asthma that is not well controlled with current treatments. It aims to see if CM326 can help reduce asthma attacks and improve breathing.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06647784Recruiting
Side versus belly lying for ARDS patients
This trial compares lying on your side versus lying on your belly to improve oxygen levels in patients with acute respiratory distress syndrome (ARDS). It may help doctors choose the best position to help you breathe better.
Bastia, FranceAges 18 years+ - NCT05913297Recruiting
Checking how Chiari malformation affects airways and sleep in children
This study looks at how Chiari malformation (types 1 and 2) may affect a child’s breathing/airways, the base of the skull, and sleep. The results may help doctors better understand which problems to watch for and how to evaluate them.
Rome, ItalyAges 3–18 - NCT05800223RecruitingPhase 3
Armatinib with or without brain radiation for EGFR lung cancer
This study tests whether armatinib alone or combined with focused brain radiation (SRT) can control brain metastases from EGFR-mutated non-small cell lung cancer. It aims to improve outcomes for people with few, mostly low-symptom brain spots.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05772455RecruitingPhase 1
Drug study for adults with solid tumors
This Phase 1 study tests XZB-0004 in adults with solid cancers to check safety and how the body responds to the drug. It may help doctors learn whether this treatment could be useful for certain tumor types, including non-small cell lung cancer.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06631989RecruitingPhase 1/Phase 2
Study of WSD0922-FU for advanced EGFR-mutant lung cancer
This trial tests a new drug called WSD0922-FU for people with advanced non-small cell lung cancer that has a specific EGFR gene change. It aims to see if the drug can help when previous EGFR treatments have stopped working.
Hefei, AnhuiAges 18–75 - NCT07575503Recruiting
Advanced CT scan to detect small blood clots in the lungs
This study tests a new type of CT scan (photon-counting CT) to see if it's better at finding small blood clots in the lungs. If you have symptoms like sudden shortness of breath, chest pain, or fainting and doctors suspect a blood clot, this trial may help confirm the diagnosis with clearer images.
Hangzhou, ZhejiangAges 18 years+ - NCT06630728RecruitingPhase 4
How Addictive Are Very Low Nicotine Little Cigars?
This study is testing whether little cigars with very low nicotine are less addictive than regular ones. Researchers want to see how smoking these affects your mood, cravings, and smoking behavior.
Columbus, OhioAges 21–75 - NCT06424392Recruiting
How lung surgery for birth defects affects kids long-term
This study follows children born with a congenital lung malformation (a lung problem present at birth) to see how surgery to remove it affects their breathing and emotional well-being over time. Your child might be eligible if they are already part of a large French research program called MALFPULM.
ParisAges 6–9 - NCT06425354Recruiting
Can breathing machine energy predict lung inflammation?
This study looks at a new measure called 'mechanical power' (the energy from the breathing machine) to see if it can predict inflammation in the lungs and blood of patients with low oxygen levels. It may help doctors better understand how the breathing machine affects lung damage.
RomaAges 18 years+ - NCT06751043Recruiting
Testing if fasting before a procedure is needed in ICU patients
This trial tests whether not eating before a procedure (called preoperative fasting) is better than fasting in ICU patients who are already receiving tube feedings. It aims to find out if skipping the fast can help you without causing extra risks.
Palo Alto, CaliforniaAges 18 years+ - NCT06956911Enrolling by invitation
Low-resistance exercise with blood flow restriction after heart surgery
This trial tests if gentle arm exercises with a special blood pressure cuff can help men recover their lung function after heart surgery. It may be an option for those who are stable and ready to follow simple instructions.
Cairo, Cairo GovernorateAges 45–60 - NCT07322783RecruitingPhase 2
Osimertinib plus savolitinib for resistant lung cancer
This trial tests a combination of two targeted drugs (osimertinib and savolitinib) for people with a specific type of advanced non-small cell lung cancer that has stopped responding to standard treatments. It may help patients whose cancer has a low number of MET gene copies.
QingdaoAges 18–80 - NCT06067100Recruiting
Effect of asthma medication on exercise in active adults
This trial tests how a common asthma medication (a long-acting beta-agonist combined with a corticosteroid) affects exercise performance in healthy, fit young adults. It may help you understand if you could join if you exercise regularly and have no asthma or heart issues.
CopenhagenAges 18–39 - NCT07584239Recruiting
Physical therapy and relaxation before lung cancer surgery
This trial tests whether physical therapy exercises and relaxation techniques done before surgery can help adults with lung cancer feel stronger, recover better, and have better surgical outcomes. You'll work with specialists to prepare your body and mind for the operation.
Columbus, OhioAges 18 years+ - NCT06429696RecruitingPhase 2
Maintenance therapy for extensive stage small cell lung cancer
This study tests if a combination of an immunotherapy drug (PD-L1 inhibitor) and a targeted therapy pill (apatinib) can help keep extensive stage small cell lung cancer from growing after initial treatment. It is for people whose cancer was controlled with first-line chemo-immunotherapy.
Guangzhou, GuangdongAges 18–75 - NCT06430437RecruitingPhase 3
Study of SHR-A1811 for first-line treatment of advanced lung cancer with HER2 mutations
This trial tests a new drug called SHR-A1811 for people with advanced or metastatic non-small cell lung cancer that has a change (mutation) in the HER2 gene. You cannot have had any previous treatment for advanced lung cancer, and the cancer must be measurable outside the brain.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06759779Recruiting
Breathing muscle training for teenage volleyball players
This study tests whether training the muscles you use to breathe in and out can help teenage volleyball players perform better. If you play volleyball at least 3 days a week and are between 12 and 18 years old, this trial might be for you.
Ankara, EmekAges 12–18 - NCT06412289Recruiting
Ultrasound vs CT for lung biopsy accuracy
This study compares two ways to take a tissue sample (biopsy) from lung growths that sit against the chest wall: one using a CT scanner and the other using an ultrasound machine. The aim is to see which method is better at getting an accurate diagnosis.
FerraraAges 18–90 - NCT07527702Recruiting
Comparing suction pressures after lung cancer surgery
This study tests two different suction pressures used on chest tubes after lung cancer surgery to see which helps patients recover better. The goal is to find the safest and most effective way to remove fluid and air from the chest cavity after surgery.
SeoulAges 19 years+ - NCT06613412Recruiting
Robot-assisted lung biopsy for suspicious lung spots
This trial tests if a remote-controlled robotic bronchoscope can safely and reliably take tissue samples from hard-to-reach spots in the lung. If you have a suspicious lung nodule that needs a biopsy, this study may help determine whether the robot-based approach works as well as standard bronchoscopy.
Guangzhou, GuangdongAges 18–75
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,618 recruiting pulmonology studies from the U.S. registry right now, out of 10,521 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.