Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,348 recruiting studies in this area right now.
By phase
- Not applicable4,048
- Phase 2836
- Phase 1458
- Phase 3420
- Phase 1/Phase 2310
- Phase 4212
- Phase 2/Phase 364
Top conditions
- Lung Cancer415
- Asthma193
- Non-Small Cell Lung Cancer183
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD133
- Breast Cancer111
- Pulmonary Hypertension104
- Colorectal Cancer89
- COVID-1988
- NSCLC87
- Chronic Obstructive Pulmonary Disease86
- Chronic Obstructive Pulmonary Disease (COPD)77
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia69
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center34
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California384
- Alabama176
- Arizona154
- Florida121
- Massachusetts120
- Maryland114
- New York113
- Texas87
- Pennsylvania81
- Illinois73
Recruiting studies6,348 total
- NCT07677059RecruitingPhase 2
Long-term study of KT-621 for asthma patients from previous study
This trial is for people with asthma who already completed a previous study of the drug KT-621. It aims to see if taking KT-621 for a longer time is safe and helpful.
Miami, FloridaAges 18 years+ - NCT07675265Recruiting
ARDS biomarker study
This study is for patients in the ICU with ARDS (a severe lung condition). It looks at biomarkers (special substances in your blood) to help understand different types of ARDS. You do not receive any treatment, but you help researchers learn more about the disease.
Urbana, IllinoisAges 18 years+ - NCT06243146Recruiting
Oxygen adjustment to prevent lung problems after surgery
This study is testing whether adjusting the amount of oxygen given during and after surgery can help reduce lung complications in people having lung surgery with a special breathing tube. The goal is to find a safer oxygen level that might keep your lungs healthier.
Chengdu, SichuanAges 18–80 - NCT06667154RecruitingPhase 2
Low-dose nivolumab plus chemo for early lung cancer
This trial tests a lower dose of the immunotherapy drug nivolumab (Opdivo) combined with standard chemotherapy before surgery for patients with early-stage non-small cell lung cancer (NSCLC). The goal is to see if this combination shrinks the tumor and improves outcomes with fewer side effects.
São José do Rio Preto, São PauloAges 18 years+ - NCT06667063Recruiting
Immune response study for COVID-19 and flu
This study looks at how your immune system responds to COVID-19 or the flu. It may help researchers understand these infections better, whether you are currently sick or healthy.
Wuhan, HubeiAges 18 years+ - NCT07677787Recruiting
PET/CT imaging for small cell lung cancer
This trial uses a special PET/CT scan to look for a protein called DLL3 in small cell lung cancer. The scan may help doctors better see and understand the cancer. You may be able to join if you have suspected or confirmed small cell lung cancer and certain blood markers are high.
Xiamen, FujianAges 18–80 - NCT07674264Recruiting
Breathing therapy for thinking and movement in Parkinson's
This study tests whether a breathing-based therapy (short bursts of controlled air with higher carbon dioxide) can help with thinking and movement in people with Parkinson's disease. It may be an option for those who are not too advanced in their condition and are healthy enough to participate.
Gainesville, FloridaAges 40–75 - NCT07676435RecruitingPhase 2
Fisetin trial for healthy lung aging
This study tests whether a natural supplement called fisetin can help slow lung decline in older adults who are either lifelong nonsmokers or long-term smokers. You would take fisetin or a placebo for a period and be monitored regularly.
Los Angeles, CaliforniaAges 60 years+ - NCT07675889Recruiting
Comparing two ways to find a small lung nodule during surgery
This study compares two ways of marking a small lung nodule before surgery to remove it. One method uses a CT scan to guide a needle into the lung before surgery, and the other method finds the nodule during the operation itself. The goal is to see which method is safer and more accurate.
Xingyi, GuizhouAges 18–80 - NCT07674953Recruiting
CPAP and oxygen delivery in preterm infants
This study looks at how different levels of CPAP (a breathing machine that helps keep the lungs open) affect oxygen delivery and lung expansion in preterm babies. It may help doctors understand the best settings for infants who need breathing support.
Little Rock, ArkansasAges Any age - NCT07672405RecruitingPhase 2
Sorfequiline-based treatment for new drug-sensitive TB
This study tests a new medicine called sorfequiline, given in a combination regimen, to treat adults with drug-sensitive TB. It aims to see if sorfequiline can work as well as or better than standard treatment and shorten the time to cure.
Wentworth, DurbanAges 18–65 - NCT07673861Recruiting
Using ctDNA to find resistance and guide cancer treatment
This trial uses a simple blood test to look for changes in your cancer's DNA that might show why your current treatment stopped working. The results could help your doctor choose your next treatment more precisely.
LondonAges 18 years+ - NCT07679321Recruiting
Anxiety & depression's effect on asthma control
This study looks at how anxiety and depression affect how well asthma medications work. It aims to help predict who might have an asthma attack, so doctors can treat you better.
Changsha, HunanAges 14 years+ - NCT07672548Recruiting
Pilates for better breathing and quality of life in postmenopausal women
This 10-week study tests whether Pilates exercises can improve lung function and overall well-being in postmenopausal women who have breathing problems. It may help you feel stronger and breathe easier.
AmmanAges 50–60 - NCT07678619Enrolling by invitation
Smart tools for infectious disease decisions
This study tests a smart analysis system to help local health officials make better decisions during infectious disease outbreaks. It aims to see if this tool improves speed and accuracy in responding to diseases like COVID-19, mpox, or flu.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07675967Recruiting
Blood Cell Changes During Cancer Treatment
This study is for people with solid tumors who are about to start chemotherapy or radiation. It looks at how these treatments affect blood cells and may help doctors understand changes in blood health over time.
Boston, MassachusettsAges 18 years+ - NCT07673250Enrolling by invitation
Personalized breathing settings for ECMO patients
This study tests whether personalized breathing machine settings can improve outcomes for people on ECMO (a heart-lung support machine). It is designed for patients who have had or are waiting for a lung or heart transplant.
La Jolla, CaliforniaAges 18 years+ - NCT07679282RecruitingPhase 4
Comparing sleep apnea treatments: CPAP, mouthpiece, or medication
This study compares three treatments for obstructive sleep apnea: a CPAP machine, a dental mouthpiece, and a combination of two medications (atomoxetine and oxybutynin). Researchers want to see which works best for people recently diagnosed with sleep apnea.
Tucson, ArizonaAges 18 years+ - NCT07672106Recruiting
Predicting breathing tube need after major surgery recovery
This study watches patients after major surgery to see which factors may increase the chance of needing a breathing tube again. It helps doctors better predict and prevent breathing problems in the intensive care unit.
Istanbul, ŞişliAges 18 years+ - NCT07676383Recruiting
Better cancer screening with community precision navigation
This trial tests a program to help people at high risk for certain cancers get the free screening tests they need. It aims to make screening easier by providing personalized guidance in the community.
Huaihua, HunanAges 45–74 - NCT07673237Recruiting
Remote monitoring for interstitial lung disease
This study tests whether using remote monitoring devices and apps at home can help track your lung health between clinic visits. It may help you stay connected with your care team and catch changes sooner.
San Francisco, CaliforniaAges 18 years+ - NCT06656299Recruiting
Nerve block for gallbladder removal surgery
This study tests a nerve block called EOIB to see if it helps reduce pain after gallbladder removal surgery. If you are having planned gallbladder surgery, this might be a good option for you.
IstanbulAges 18–65 - NCT05435248RecruitingPhase 1/Phase 2
Study drug for advanced lung cancer with a specific EGFR change
This Phase 1/2 trial tests HS-10375, a study drug, in people with advanced or metastatic non-small-cell lung cancer (NSCLC) whose cancer has a specific EGFR mutation (C797S). It may help by targeting that mutation when standard treatments are not an option.
Guangzhou, GuangdongAges 18 years+ - NCT06178510Recruiting
Breathing support after heart surgery
This trial tests a new way to help patients breathe after heart surgery. It compares standard breathing support with a new device that might help you recover faster in the ICU.
Vienna, State of ViennaAges 18–120
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,348 recruiting pulmonology studies from the U.S. registry right now, out of 9,933 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.