Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,618 recruiting studies in this area right now.
By phase
- Not applicable4,293
- Phase 2848
- Phase 1470
- Phase 3423
- Phase 1/Phase 2310
- Phase 4207
- Phase 2/Phase 367
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer179
- Non-small Cell Lung Cancer171
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer109
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Pneumonia78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Riphah International University34
Where studies are running
- California389
- Alabama174
- Arizona154
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas89
- Pennsylvania84
- Colorado71
Recruiting studies6,618 total
- NCT07171606RecruitingPhase 2
Study of a new drug for advanced lung cancer
This trial tests a new drug called SSGJ-706, either alone or with other treatments, for people with advanced non-small cell lung cancer (NSCLC) that has spread or cannot be surgically removed. The goal is to see if it helps shrink or control the cancer.
ShanghaiAges 18–75 - NCT06499389Recruiting
Breathing muscle therapy for hard-to-wean ICU patients
This study tests a special breathing therapy for intensive care patients who are having trouble coming off the ventilator. If you have weak muscles or a weak cough, the therapy aims to strengthen your breathing so you can recover faster.
Lyon, FranceAges 18 years+ - NCT06131112Recruiting
PET scan for heart inflammation in sarcoidosis
This study tests if a special PET scan with 64Cu-DOTATATE can detect inflammation in the heart caused by sarcoidosis. It may help diagnose heart sarcoidosis more accurately in people with symptoms or known disease.
CopenhagenAges 18 years+ - NCT07280611Recruiting
Breathing reflex study in double lung transplant patients
This study looks at a natural breathing reflex (the Hering-Breuer reflex) in people who have had a double lung transplant and are on a ventilator in the ICU. It compares them with other ICU patients who are on a ventilator after non-chest surgery, to see how the reflex works after a lung transplant.
Milan, MichiganAges 18 years+ - NCT02480283Recruiting
Study of cannabis smoke and lung immune response
This study compares people who smoke cannabis daily with people who have never used cannabis. It looks at how cannabis smoke affects lung stress and the lungs’ immune defenses, using health tests and urine screening to keep participants safe.
Aurora, ColoradoAges 18–55 - NCT06306638RecruitingPhase 1/Phase 2
Light therapy after radiation for inoperable airway tumors
This trial tests a new light-activated therapy (interstitial photodynamic therapy) after palliative radiation to shrink inoperable airway tumors and improve breathing. It is for people with solid cancers that block the airway from the outside and cannot be removed with surgery.
Buffalo, New YorkAges 18 years+ - NCT07388680RecruitingPhase 2/Phase 3
Pirfenidone for radiation lung injury with or without immune pneumonia
This trial tests if pirfenidone capsules can help treat lung damage caused by radiation therapy, with or without immune-related pneumonia. It may be suitable for people with mild to moderate lung function impairment who have recently developed radiation lung injury.
Hefei, AnhuiAges 18–75 - NCT07279831Recruiting
Brain-lung interaction study in acute respiratory failure
This trial looks at how the lung and brain communicate during serious breathing problems. If you are in the ICU with a new breathing issue and need high-flow oxygen therapy, researchers want to study your brain and lung activity together.
ParisAges 18 years+ - NCT07277244Enrolling by invitation
Gentle breathing support during robot surgery
This study tests a low-pressure breathing method during robot-assisted surgery to see if it helps protect your lungs. It's for adults having abdominal or pelvic surgery expected to last at least 2 hours.
Boston, MassachusettsAges 18 years+ - NCT06902766Recruiting
Digital asthma management for children aged 4 to 12
This trial tests whether a smartphone app and digital inhalers can help monitor and manage asthma in children. It may help parents track treatment better and improve asthma control.
ParisAges 4–12 - NCT06962436Recruiting
Comparing Robotic vs. Ultrathin Bronchoscopy for Lung Nodules
This trial compares two types of bronchoscopy (thin-tube lung camera) methods to see which one better samples lung nodules. You may be able to join if you have a suspicious lung nodule and need a biopsy.
Jinan, ShandongAges 18 years+ - NCT06482983Recruiting
Two breathing methods for women having laparoscopic gynecologic surgery
This study compares two ways of helping you breathe during surgery to see which one is better for your brain and lungs. The results may help doctors choose the safest method for people like you.
Istanbul, UmraniyeAges 18–70 - NCT07326072Enrolling by invitation
Enb with ultra-thin cryobiopsy for lung nodule diagnosis
This study tests a new way to get tissue samples from small lung nodules using a special scope and freezing technique. It may help diagnose cancer without more invasive procedures.
Beijing, Beijing MunicipalityAges 18–90 - NCT06961227Recruiting
Comparing two breathing machine settings in the ICU
This trial compares two different ways a breathing machine can help you breathe. It uses a special imaging technique to see which method works better for patients in the intensive care unit.
SanliurfaAges 18 years+ - NCT07178795RecruitingPhase 3
New drug vs standard care for HER2-mutant lung cancer
This study is testing a new drug (BL-M07D1) compared to a standard combination of pembrolizumab and chemotherapy for people with a specific type of advanced lung cancer (non-squamous NSCLC) that has a HER2 mutation and has not been treated before. The goal is to see which treatment works better.
Guangzhou, GuangdongAges 18–75 - NCT06483282RecruitingPhase 2
Study of immunotherapy plus targeted therapy and chemo before surgery for lung cancer
This trial tests a combination of immunotherapy (adebrelimab), a targeted therapy (apatinib), and chemotherapy given before surgery for people with limited-stage small cell lung cancer. The goal is to see if this treatment shrinks the tumor enough to make surgery more effective and to study markers that might predict response.
Hangzhou, ZhejiangAges 18–75 - NCT07272798Recruiting
Heart confidence after pulmonary hypertension surgery
This study looks at how confident patients feel about managing their heart health after surgery for chronic thromboembolic pulmonary hypertension. It may help doctors understand how to better support recovery.
Damascus, Rif-dimashq GovernorateAges Any age - NCT06820593Recruiting
Asthma care with technology for kids and families
This study tests whether a sensor that tracks inhaler use can help children ages 4–17 with persistent or uncontrolled asthma. It aims to make managing asthma at home easier for caregivers.
Chicago, IllinoisAges 4 years+ - NCT06514378RecruitingPhase 1
Safety of stem cells for chronic lung transplant rejection
This trial tests whether a single dose of stem cells given through a bronchoscope is safe for people whose lungs are failing after a transplant. It may help those with a condition called bronchiolitis obliterans syndrome (BOS), a type of chronic rejection that makes it harder to breathe.
MadridAges 18 years+ - NCT07227389Recruiting
Opioid Timing and Breathing Risk After Surgery
This study looks at when opioids are given during surgery and how it affects breathing problems after surgery. It might help understand how to make pain control safer.
Detroit, MichiganAges 18–85 - NCT07265882Recruiting
Bedside test for breathing tube patients
This trial uses a simple bedside test to evaluate patients who are on a breathing machine and not breathing on their own. It may help doctors better understand and manage acute respiratory failure.
Pavia, PaviaAges 18–90 - NCT06925009Recruiting
Predicting the best way to place a breathing tube
This study compares two methods (a special camera called a videolaryngoscope and an ultrasound) to help doctors choose the best way to place a breathing tube during surgery. It aims to make airway management safer and more personalized for patients like you.
Madrid, MadridAges 18–90 - NCT06926608Recruiting
Helping Latinos quit smoking and get active
This trial is for Hispanic or Latino adults who smoke and want to quit. It tests a program that combines text messages and a wearable activity tracker to help you quit smoking and become more physically active.
Rochester, New YorkAges 18 years+ - NCT06517953RecruitingPhase 2
Testing two targeted pills for rare EGFR lung cancer
This study tests two oral targeted drugs, Befotertinib and Icotinib, in people with advanced lung cancer (NSCLC) that has one of three uncommon EGFR mutations. The trial aims to see how well these pills work when used as the first treatment for your cancer.
Guangzhou, GuangdongAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,618 recruiting pulmonology studies from the U.S. registry right now, out of 10,521 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.