Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,618 recruiting studies in this area right now.
By phase
- Not applicable4,293
- Phase 2848
- Phase 1470
- Phase 3423
- Phase 1/Phase 2310
- Phase 4207
- Phase 2/Phase 367
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer179
- Non-small Cell Lung Cancer171
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer109
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Pneumonia78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Riphah International University34
Where studies are running
- California389
- Alabama174
- Arizona154
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas89
- Pennsylvania84
- Colorado71
Recruiting studies6,618 total
- NCT05572177Recruiting
Smartphone app to help manage asthma day to day
This trial tests whether a smartphone app can help people with ongoing (persistent) asthma manage their symptoms and care more effectively. You may be asked to use the app regularly during the study.
Tampa, FloridaAges 12–17 - NCT05703191Recruiting
Tests an inhaled nitric oxide system for newborn lung pressure
This study looks at whether an inhaled nitric oxide generator and delivery system can help newborns with high lung blood pressure (pulmonary hypertension). It may help improve oxygen levels during breathing support, but it requires specific medical eligibility and informed consent.
Guangzhou, GuangzhouAges Any age - NCT07327619RecruitingPhase 3
Testing a New Antibiotic Combo for Hospital-Acquired Pneumonia
This trial tests a combination of two antibiotics (meropenem and pralurbactam) to see if they work better than other treatments for people with pneumonia that started in the hospital or from a breathing machine. If you qualify, this study might offer you a new treatment option.
Huaihua, HunanAges 18–80 - NCT06903117RecruitingPhase 1
CAR T-Cell Therapy for CEA-Positive Advanced Lung Cancer
This early-stage trial tests a special immune cell treatment (CAR T cells) designed to target and attack lung cancer cells that have a protein called CEA on their surface. It's for people with advanced lung cancer who have already tried at least two standard treatments without success.
ShanghaiAges 18 years+ - NCT07596589RecruitingPhase 3
Remimazolam sedation for breathing-machine patients in ICU
This study tests whether a sedative medication called remimazolam helps patients on breathing machines (ventilators) in the ICU recover better and have fewer complications. You would receive this medication to keep you calm and comfortable while on the ventilator.
Nanjing, JiangsuAges 18 years+ - NCT06491017Recruiting
Better airway clearance for ventilated patients
This trial tests if a special machine (mechanical insufflation-exsufflation) can help remove thick mucus from the lungs of patients who are on a breathing tube and ventilator. The goal is to see if optimized settings clear more mucus than standard care.
BarcelonaAges 18 years+ - NCT06603350Recruiting
How surgery factors affect recovery after lung transplant
This study looks at how things before, during, and right after lung transplant surgery affect recovery. Researchers want to learn what helps patients heal better so they can improve care.
Hangzhou, ZhejiangAges 18 years+ - NCT06792188Recruiting
Using a smartwatch to predict sleep apnea
This trial tests if a smartwatch can help predict sleep apnea in people who have symptoms like snoring or daytime sleepiness. It may offer a simpler way to identify the condition.
SeoulAges 22–85 - NCT06879600Recruiting
High-flow oxygen for emergency surgery patients with full stomachs
This trial tests if using high-flow oxygen through the nose before surgery helps patients who need emergency surgery and have a full stomach. It may make oxygen levels safer during the start of anesthesia.
Viet Tri, Phu ThoAges 18 years+ - NCT07367529RecruitingPhase 1/Phase 2
Study of TQB6411 for people with lung cancer
This trial tests a new drug called TQB6411 for people with lung cancer. It aims to see if the drug is safe and effective, and what side effects it might have.
Beijing, Beijing MunicipalityAges 18–75 - NCT06885970Recruiting
Cytisine for smoking cessation and heart health
This study tests whether a medicine called cytisine can help people quit smoking and how it might affect their heart health. If you are a smoker without serious heart, liver, kidney, or immune problems, you may be able to join.
Athens, HaidariAges 18–75 - NCT07157215Recruiting
Survey on non-invasive ventilation outside the ICU
This survey asks healthcare workers about their use of non-invasive breathing support in patients with serious breathing problems. Your answers could help improve care for people needing this treatment.
Lucknow, Uttar PradeshAges 18 years+ - NCT07309276RecruitingPhase 2
Study of JS212 for advanced lung cancer
This trial tests a new drug called JS212 combined with other treatments for people with advanced or spreading lung cancer. It aims to see if the combination can help shrink tumors or slow the disease.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05889247Recruiting
Blood test guided monitoring for advanced lung cancer treatment
This trial checks whether a blood test that looks for cancer DNA can help guide and monitor treatment in people with advanced non-small cell lung cancer (NSCLC). It may help your team spot treatment response or changes earlier, so care can be adjusted appropriately.
Hillerød, Region HAges Any age - NCT05717218Recruiting
Testing special breathing monitoring during VV-ECMO in ARDS
This trial checks whether a special “breathing sensor belt” that watches breathing in real time can be used safely in adults with severe lung failure (ARDS) who are on a machine called VV-ECMO. It may help the care team better monitor ventilation while you’re critically ill.
ParisAges 18 years+ - NCT05718245Recruiting
HEPA air filters to improve heart and blood sugar health
This study looks at whether using HEPA air filters and monitoring indoor air can improve heart-related health and blood sugar/metabolic health in older adults. You may be eligible if you live in Los Angeles County, don’t smoke, and meet the health and home requirements.
Los Angeles, CaliforniaAges 65–84 - NCT07301697Recruiting
Cryobiopsy safety study in bronchial endoscopy
This trial is studying a procedure called cryobiopsy, which uses extreme cold to take tissue samples from the lungs. It aims to see how safe and effective it is for diagnosing conditions like interstitial lung disease or lung cancer, especially when other tests haven't worked.
StrasbourgAges 18 years+ - NCT04616313Recruiting
MRI and breathing tests in people who vape
This study uses a special lung scan (MRI) and breathing tests to understand how vaping affects lung structure and function. It may help researchers learn what early lung changes happen after starting vaping, even if you don’t feel sick.
London, OntarioAges 16 years+ - NCT06864624RecruitingPhase 2
Perioperative sunvozertinib for stage II-IIIB NSCLC with EGFR exon 20 insertion
This trial tests the drug sunvozertinib before and after surgery for non-small cell lung cancer that has a specific EGFR mutation (exon 20 insertion). It aims to see if the drug can help shrink tumors and improve outcomes for patients whose cancer is at stage II, IIIA, or IIIB.
Changsha, HunanAges 18 years+ - NCT07161050Recruiting
Low nicotine and price effects on illegal cigarette buying
This study looks at how low-nicotine cigarettes and higher cigarette prices affect people's choices to buy illegal or cheaper cigarettes. It may help understand how to reduce smoking.
Roanoke, VirginiaAges 21 years+ - NCT07293299Recruiting
PneumoRator monitoring study for planned surgery
This study tests a new device, the PneumoRator, which monitors your breathing and oxygen during surgery. It may help doctors track your recovery after major surgery.
SouthamptonAges 18 years+ - NCT06852924Recruiting
Inhaled nitric oxide for HAPE treatment trial
This trial tests if inhaled nitric oxide helps people with high-altitude pulmonary edema (fluid in the lungs from high altitude). It may offer a new treatment option for those with mild to moderate symptoms.
Lhasa, TibetAges 18–65 - NCT07289958Recruiting
Breathing muscle training after weight loss surgery
This study tests whether breathing exercises can help people recovering from weight loss (bariatric) surgery. It may improve your breathing and recovery after the procedure.
Quito, PichinchaAges 18–60 - NCT05984394Recruiting
Study of immune cells in new antisynthetase syndrome with lung disease
This study looks at special immune cells (T cells) in people newly diagnosed with antisynthetase syndrome that has affected their lungs. It aims to understand how these cells are involved in the condition, which could lead to better treatments.
DijonAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,618 recruiting pulmonology studies from the U.S. registry right now, out of 10,521 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.