Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,347 recruiting studies in this area right now.
By phase
- Not applicable4,045
- Phase 2834
- Phase 1458
- Phase 3422
- Phase 1/Phase 2311
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer415
- Asthma193
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD133
- Breast Cancer111
- Pulmonary Hypertension104
- COVID-1988
- Colorectal Cancer88
- NSCLC87
- Chronic Obstructive Pulmonary Disease85
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia69
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California383
- Alabama175
- Arizona154
- Florida121
- Massachusetts120
- Maryland114
- New York111
- Texas87
- Pennsylvania81
- Illinois73
Recruiting studies6,347 total
- NCT07334379RecruitingPhase 2
Personalized treatment for hospitalized patients with breathing problems
This study tests a personalized approach for hospitalized patients with acute breathing problems. It uses a blood test to guide whether they receive a common steroid or a targeted medication (tocilizumab) to reduce inflammation, with the goal of improving recovery.
Toronto, OntarioAges 18 years+ - NCT07339644Recruiting
Lung-Sparing Radiation Guided by Breathing Scans
This study tests a new way to plan radiation for lung tumors. It uses a breathing-guided scan to map healthy and unhealthy parts of the lungs, so radiation can avoid working lung tissue. The goal is to see if this approach spares more healthy lung while still treating the cancer.
ChongqingAges 18–85 - NCT07340255Recruiting
Safe airway pressure during anesthesia start
This study tests the best air pressure to use with a mask to keep air out of the stomach when you first go to sleep for surgery. It helps make anesthesia safer and more comfortable for you.
JiaxingAges 18–65 - NCT07340892Recruiting
Finding markers to predict lung inflammation from immunotherapy
This study looks for signs in the blood that can tell if a lung cancer patient is developing a side effect called pneumonitis (lung inflammation) from checkpoint inhibitor treatment. It may help doctors catch and treat this side effect early.
Guangzhou, GuangdongAges 18 years+ - NCT07337096Recruiting
Electro-acupuncture for advanced lung cancer: the EALER study
This study tests whether adding electro-acupuncture (a gentle type of acupuncture with mild electrical pulses) to standard first-line immunotherapy and chemotherapy can help people with advanced non-small cell lung cancer. It aims to see if this combination improves quality of life and overall treatment outcomes.
Guangzhou, GuangdongAges 18 years+ - NCT07342920Recruiting
Smoking and vaping in adults with cystic fibrosis
This study looks at how many adults with cystic fibrosis smoke or vape (use e-cigarettes). It aims to understand how common these habits are in this group.
StrasbourgAges 18 years+ - NCT07342205RecruitingPhase 2/Phase 3
Fecal transplant for sepsis-related lung injury
This study tests if transferring healthy gut bacteria (fecal microbiota transplant) can help people with acute lung injury caused by sepsis. It aims to reduce inflammation and improve breathing.
Shanghai, PutuoAges 18 years+ - NCT06142773Recruiting
Brain activity and breathing during MRI
This study looks at how brain activity relates to the depth of your breaths during an MRI scan while you are under anesthesia. It may help doctors better understand breathing control during surgery.
Toronto, OntarioAges 18 years+ - NCT05463913RecruitingPhase 4
Scan and spot lung nodules with special PET/CT
This trial tests a newer PET/CT scan method to detect uncertain (indeterminate) lung nodules more accurately before biopsy or surgery. If you have a small lung nodule that doctors are still unsure about, this could help improve how nodules are found and assessed.
GroningenAges 18–100 - NCT06862895Recruiting
Chest therapy for babies with bronchiolitis
This trial tests whether gentle chest physiotherapy can help babies with bronchiolitis (a lung infection) recover better. It looks at how the therapy affects their breathing and overall health.
Erbil, KurdistanAges 1 month–1 year - NCT06862297Recruiting
Comparing a new jaw tracking device to standard sleep study for sleep apnea
This study compares a new device that tracks jaw movement during sleep to the standard sleep study (polysomnography) for diagnosing sleep apnea. You may be eligible if you have symptoms like loud snoring or daytime sleepiness and have been referred for a sleep study.
TaipeiAges 20–75 - NCT05190718Recruiting
Pharyngeal electrical stimulation for swallowing trouble after brain injury
This trial tests a non-drug therapy that uses gentle electrical stimulation to help people swallow safely when swallowing is affected by certain brain or nerve conditions. If you qualify, you may receive this approach to improve swallowing and reduce choking risk.
Tulln, Low AustriaAges 18 years+ - NCT06374147Recruiting
Vibrating pad for apnea in very premature babies
This trial is testing a special vibrating pad (Prapela®) placed in the incubator to see if it can help reduce apnea episodes (pauses in breathing) in very premature babies. It is for babies who are already getting caffeine medicine and need only minimal extra breathing support.
Birmingham, AlabamaAges birth–3 months - NCT06748937RecruitingPhase 2
Testing alpibectir plus ethionamide for new TB
This study tests an experimental oral TB drug called alpibectir given together with ethionamide for people with newly diagnosed lung TB. The goal is to see how well the combination works and if it is safe.
Cape Town, Western CapeAges 18–65 - NCT07326449Enrolling by invitation
CO2 measurement test on exercise bike
This trial checks if a portable device can reliably measure carbon dioxide in your breath while you rest and cycle slowly. It may help understand how your lungs work during light exercise.
LinköpingAges 18–70 - NCT06863506RecruitingPhase 2
Study of Befotertinib for non-small cell lung cancer with uncommon EGFR mutations
This trial tests a drug called Befotertinib for people with non-small cell lung cancer that has uncommon EGFR mutations (like G719X, L861Q, S768I, or exon 20 insertions). It is for those who haven't taken an EGFR-targeted pill before and have had a previous chemotherapy stopped working or caused side effects.
Hangzhou, ZhejiangAges 18 years+ - NCT07326540RecruitingPhase 3
Testing a new antibiotic for drug-resistant pneumonia in the hospital
This trial compares a new antibiotic (BV100 plus low-dose polymyxin B) against a standard treatment for pneumonia caused by a hard-to-treat bacteria (Acinetobacter baumannii). If you have hospital-acquired or ventilator-associated pneumonia and standard antibiotics aren't working, this study may offer a new option.
TbilisiAges 18–82 - NCT07334119RecruitingPhase 1
Testing MT-304 for advanced HER2-positive tumors
This trial tests a new drug, MT-304, for people with advanced cancers that have high levels of a protein called HER2. It aims to see if the drug is safe and helps shrink tumors.
Darlinghurst, New South WalesAges 18 years+ - NCT07325136RecruitingPhase 1/Phase 2
BMS-986525 for Relapsed Small Cell Lung Cancer
This study tests a new drug called BMS-986525, alone or with other treatments, for people with small cell lung cancer that has come back or not responded to treatment. It aims to find out if the drug is safe and tolerable.
Detroit, MichiganAges 18 years+ - NCT07333183RecruitingPhase 2
Mosliciguat plus treprostinil for lung disease with pulmonary hypertension
This trial tests a new medicine called mosliciguat combined with an inhaled treatment (treprostinil) for people who have both scarring lung disease (interstitial lung disease) and high blood pressure in the lungs. It aims to see if this combination can improve how well you feel and function.
Santa Barbara, CaliforniaAges 18–85 - NCT07327619RecruitingPhase 3
Testing a New Antibiotic Combo for Hospital-Acquired Pneumonia
This trial tests a combination of two antibiotics (meropenem and pralurbactam) to see if they work better than other treatments for people with pneumonia that started in the hospital or from a breathing machine. If you qualify, this study might offer you a new treatment option.
Huaihua, HunanAges 18–80 - NCT07331285Recruiting
Genio therapy study for moderate to severe sleep apnea
This trial studies a device called Genio that is implanted to help keep your airway open while you sleep. It is for people with moderate to severe sleep apnea who have not been helped by other treatments.
Miami, FloridaAges 22 years+ - NCT07326995RecruitingPhase 2
Inhaled PA9159 for Adults with Moderate Asthma
This trial tests a new inhaled medicine called PA9159 for adults with moderate asthma. It compares the medicine to a placebo to see if it safely improves breathing and controls asthma symptoms.
Nanchang, JiangxiAges 18–75 - NCT07329322RecruitingPhase 2
Drug combo before surgery for EGFR-mutated lung cancer
This trial tests a combination of two targeted drugs (sacituzumab tirumotecan and osimertinib) before surgery for people with a specific type of lung cancer (EGFR-mutated). The goal is to see if the drugs can shrink the tumor enough to improve surgery results.
BeijingAges 18–75
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,347 recruiting pulmonology studies from the U.S. registry right now, out of 9,965 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.