Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 8,195 recruiting studies in this area right now.
By phase
- Not applicable6,798
- Phase 2512
- Phase 1258
- Phase 3245
- Phase 4213
- Phase 1/Phase 298
- Phase 2/Phase 371
Top conditions
- Depression422
- Anxiety415
- Alzheimer Disease341
- Autism Spectrum Disorder258
- Dementia226
- Mild Cognitive Impairment199
- Schizophrenia192
- Major Depressive Disorder189
- Cognitive Impairment157
- Insomnia152
- Alcohol Use Disorder150
- Opioid Use Disorder145
- Stress136
- PTSD110
- Autism95
- Mental Health92
- Suicidal Ideation92
- Anxiety Disorders85
Leading sponsors
- VA Office of Research and Development103
- Yale University95
- Massachusetts General Hospital78
- Stanford University72
- Assistance Publique - Hôpitaux de Paris65
- Johns Hopkins University63
- University of California, Los Angeles61
- The University of Hong Kong52
- University of Pennsylvania51
- Karolinska Institutet50
Where studies are running
- California530
- New York268
- Massachusetts263
- Texas223
- Maryland176
- Pennsylvania175
- Florida153
- Alabama118
- Arizona117
- Connecticut113
Recruiting studies8,194 total
- NCT07146802Recruiting
Personalized thinking training for psychosis
This trial tests a personalized thinking training program for people with schizophrenia to help reduce symptoms like delusions or suspiciousness. It might be a good fit if you have had some of these symptoms recently and are stable on your current treatment.
StrasbourgAges 18–65 - NCT07480525Recruiting
Escitalopram for first-time depression
This trial tests whether escitalopram, a common antidepressant, helps people who are experiencing their first episode of depression and have never taken medication for it. It also looks at how the drug works in the brain.
Beijing, Beijing MunicipalityAges 18–65 - NCT07389135Recruiting
Heart rate and anxiety after nose surgery study
This study looks at whether your heart rate patterns and anxiety levels before surgery can predict how you will wake up after nose surgery (septorhinoplasty). If you are scheduled for this surgery, they will measure your heart rate and ask you questions about anxiety to see if these can help reduce confusion or agitation when you wake up.
Konya, KaratayAges 18–65 - NCT03811964Recruiting
Test how light affects your sleep, mood, nerves, and vision
This study uses a light-based test (the “photomotor reflex”) to see how non-visual effects of light may affect sleep-wake timing, brain function, mental health, and eyesight. You may be assigned to a group based on your condition, or you may be in the healthy control group.
StrasbourgAges 18 years+ - NCT06638450Recruiting
Acupuncture for Teens with Stress and Insomnia
This study tests whether acupuncture can help teenagers who have been feeling anxious or down and having trouble sleeping. If you've had these feelings for more than 3 months and haven't taken medicine or had acupuncture recently, you may be able to join.
Hong Kong, Hong KongAges 15–22 - NCT03932773Recruiting
Check rTMS treatment for combat-related PTSD in veterans
This trial tests whether a non-drug brain stimulation treatment (rTMS) can reduce symptoms of PTSD in veterans who were exposed to post-9/11 combat trauma. It may help by improving PTSD symptoms, but you must meet safety rules—especially related to seizure risk.
Tallahassee, FloridaAges 18–60 - NCT05643144Recruiting
Shared decisions for dementia and diabetes care
This study tests a program that helps people with both memory problems (like dementia or mild cognitive impairment) and diabetes, along with their caregivers, make better care decisions together. It uses a special device to track blood sugar without fingersticks.
Indianapolis, IndianaAges 65 years+ - NCT05715411Recruiting
Light therapy for long sleep-onset insomnia
This trial studies whether timed light exposure can help people who have trouble falling asleep. It aims to improve insomnia symptoms by testing a light-based approach while carefully measuring sleep patterns.
StrasbourgAges 30–60 - NCT06976216RecruitingPhase 3
Study of KarXT plus KarX-EC for Alzheimer's cognitive symptoms
This trial tests a new combination treatment (KarXT plus KarX-EC) to see if it can help with thinking and memory problems caused by Alzheimer's disease. It is for people with mild to moderate Alzheimer's who have a caregiver available.
Long Beach, CaliforniaAges 60–85 - NCT07550075Recruiting
Support program for Korean American dementia caregivers
This study tests a virtual support program designed specifically for Korean American adults who care for family members with dementia. The program aims to help caregivers manage stress and learn practical caregiving skills through online classes.
Los Angeles, CaliforniaAges 18 years+ - NCT06817980Recruiting
Sense of self and physical activity study
This study looks at how physical activity affects your sense of self in people with schizophrenia, borderline personality disorder, or inner ear disorders. It involves vision tests, exercise, and questionnaires.
StrasbourgAges 18–60 - NCT04150198Recruiting
PET-MR brain scan study of resilience in Alzheimer’s
This study uses a combined PET and MRI brain scan to understand why some people with Alzheimer’s (and related “focal” types) may cope better than expected. It may help researchers find brain patterns linked to resilience and to different Alzheimer’s subtypes.
OrsayAges 40–80 - NCT05776316Recruiting
Harm-reduction support for adults using opioids
This trial offers harm-reduction services for adults who have been misusing opioids (and sometimes other substances) recently. It’s designed to test support approaches that may reduce risks and improve well-being.
New Haven, ConnecticutAges 18 years+ - NCT06112067Recruiting
Brain implant for severe mental health conditions
This trial tests a brain implant called deep brain stimulation (DBS) for people with severe mental health conditions that have not improved with usual treatments. The goal is to see if it can reduce symptoms and improve quality of life.
ShanghaiAges 18–65 - NCT06071221Recruiting
Mental health program for home health aides
This study tests a program to help home health aides feel better mentally. If you are a home health aide who speaks English or Spanish, has mild depression, high stress, or loneliness, and has at least 1 year of experience, you may be able to join.
New York, New YorkAges 18 years+ - NCT06678789Recruiting
Testing low vs high nicotine pouches for smokers
This study compares how low and high nicotine pouches affect adult smokers who want to try a tobacco-free option. You'll attend two visits in Charleston to check health markers.
Charleston, South CarolinaAges 21 years+ - NCT05081596Recruiting
Primary care program for mood and thinking in early Alzheimer’s
This trial tests a psychosocial (talk/behavior/support) program delivered through primary care to improve thinking and depression symptoms in older adults with mild cognitive problems and early Alzheimer’s. It may help if you have early memory/thinking changes plus mild depressive symptoms and you can work with a caregiver or study partner.
White Plains, New YorkAges 60 years+ - NCT07768670Recruiting
Smartphone exercise program for older adults
This study tests a personalized exercise program delivered through a smartphone app to help older adults become more active. You would use the app to get exercise recommendations and track your progress.
Knoxville, TennesseeAges 65 years+ - NCT07741071RecruitingPhase 2
Vitamin B3 supplement for early Alzheimer's disease
This study tests whether a daily supplement (nicotinamide riboside, a form of vitamin B3) can slow the progression of early Alzheimer's disease over two years. It is a randomized, double-blind trial, meaning half the participants will get the supplement and half will get a placebo (a pill with no active ingredient), and neither you nor the doctors will know which you are getting.
BergenAges 50–85 - NCT06606002Recruiting
Group therapy for borderline symptoms in teens
This study tests if group schema therapy helps teenagers reduce borderline personality symptoms. It may be a good option if you have some borderline traits and can attend group sessions in Finnish.
Turku, Southwest FinlandAges 15–22 - NCT04982757Enrolling by invitation
Accelerated TMS to treat depression or OCD
This trial tests an “accelerated” form of transcranial magnetic stimulation (TMS) to reduce symptoms of depression or obsessive-compulsive disorder (OCD). You may be considered if standard treatments didn’t help (or you couldn’t tolerate them), and if it’s safe for you to receive TMS.
New York, New YorkAges 18–75 - NCT07771205Recruiting
Aromatherapy for surgical anxiety and pain
This study tests whether breathing in relaxing scents before surgery can reduce anxiety and pain. If effective, it could offer a simple, drug-free way to help you feel calmer during your procedure.
Stockton, CaliforniaAges 18 years+ - NCT05776056RecruitingPhase 4
Methylphenidate for PTSD with memory and thinking problems
This study tests whether methylphenidate, a medication commonly used for attention issues, can help veterans with PTSD who also have memory or concentration problems. The goal is to see if it improves these cognitive symptoms.
Birmingham, AlabamaAges 18–65 - NCT07772401Recruiting
Ear nerve stimulation for social anxiety disorder
This trial tests a non-invasive treatment that uses a small device to stimulate a nerve in the ear, which may help reduce social anxiety symptoms. It is being studied in adults with a clinical diagnosis of social anxiety disorder who are currently experiencing significant anxiety.
Hangzhou, ZhejiangAges 18–70
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 8,195 recruiting psychiatry studies from the U.S. registry right now, out of 13,258 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.