Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 8,195 recruiting studies in this area right now.
By phase
- Not applicable6,798
- Phase 2512
- Phase 1258
- Phase 3245
- Phase 4213
- Phase 1/Phase 298
- Phase 2/Phase 371
Top conditions
- Depression422
- Anxiety415
- Alzheimer Disease341
- Autism Spectrum Disorder258
- Dementia226
- Mild Cognitive Impairment199
- Schizophrenia192
- Major Depressive Disorder189
- Cognitive Impairment157
- Insomnia152
- Alcohol Use Disorder150
- Opioid Use Disorder145
- Stress136
- PTSD110
- Autism95
- Mental Health92
- Suicidal Ideation92
- Anxiety Disorders85
Leading sponsors
- VA Office of Research and Development103
- Yale University95
- Massachusetts General Hospital78
- Stanford University72
- Assistance Publique - Hôpitaux de Paris65
- Johns Hopkins University63
- University of California, Los Angeles61
- The University of Hong Kong52
- University of Pennsylvania51
- Karolinska Institutet50
Where studies are running
- California530
- New York268
- Massachusetts263
- Texas223
- Maryland176
- Pennsylvania175
- Florida153
- Alabama118
- Arizona117
- Connecticut113
Recruiting studies8,194 total
- NCT07780331Recruiting
Virtual reality and games to reduce fear in children using inhalers
This study tests whether using virtual reality glasses or playing games on a tablet can help reduce fear and anxiety in young children (aged 4-6) when they need to take medication through an inhaler or nebulizer. It aims to see if these distractions make the experience more comfortable.
Balıkesir, BalıkesirAges 4–6 - NCT07779759Recruiting
Speech therapy intensity for children with speech sound disorders
This study compares two different levels of speech therapy (high-intensity versus low-intensity) to see which is more effective for children aged 4 to 12 who have difficulty making certain speech sounds correctly.
GhentAges 4–12 - NCT07775079Recruiting
Comparing exercise training approaches for older adults with mild memory problems
This study tests two different ways of combining physical and mental exercises to see which helps older adults with mild to moderate memory problems improve their thinking and daily function better.
Islamabad, IslamabadAges 4.6 years–7.1 years - NCT07695246Recruiting
Sleep therapy with melatonin for older adults with insomnia
This study tests whether adding a melatonin supplement to a type of talk therapy for insomnia (called CBT-I) helps older adults sleep better. It aims to improve sleep quality and reduce insomnia symptoms.
Hong KongAges 60 years+ - NCT05931913Recruiting
TMS plus exposure therapy for teenage OCD
This study tests whether combining transcranial magnetic stimulation (TMS) with exposure therapy can help reduce OCD symptoms in young people aged 12-21. TMS is a non-invasive brain stimulation technique. The study aims to see if this combination is more effective than exposure therapy alone.
Minneapolis, MinnesotaAges 12–21 - NCT07780097Recruiting
Starting opioid addiction medication after a hospital stay
This study helps people who are in the hospital for opioid use disorder start a medication like methadone or buprenorphine after they leave the hospital. It aims to make starting treatment easier and improve recovery.
Cincinnati, OhioAges 18 years+ - NCT07158905RecruitingPhase 1
Tau vaccine study for early Alzheimer's prevention
This study tests a vaccine that targets tau protein, which is linked to Alzheimer's disease. It is for older adults who have no memory problems yet but have biological signs of early Alzheimer's, to see if the vaccine can prevent or slow down the disease.
Boca Raton, FloridaAges 65–80 - NCT06594627Recruiting
Smart pillow study for better sleep with snoring or sleep apnea
This study tests a smart pillow device to see if it can improve sleep quality for people over 50 who snore or have mild sleep apnea. It also looks at how the pillow affects sleep partners.
Indianapolis, IndianaAges 50 years+ - NCT07595068Recruiting
Ultrasound for Sleep and Heart Function Before Heart Surgery
This trial tests a new treatment using focused ultrasound to help regulate your nervous system and improve sleep quality before heart surgery. The goal is to help reduce anxiety and improve how well you sleep during the time leading up to and after your cardiology procedure.
Huangshi, HubeiAges 18–79 - NCT07542730RecruitingPhase 4
Diphenhydramine to ease discomfort during early abortion procedure
This study tests whether adding diphenhydramine (a common allergy medicine) to sedation helps patients feel more comfortable during a procedural abortion in the first trimester. Researchers want to see if it improves pain control and overall experience.
Rochester, New YorkAges 18 years+ - NCT07646678RecruitingPhase 2/Phase 3
TAK-360 Extension Study for Narcolepsy or Excessive Sleepiness
This is a follow-up study for people who already completed a TAK-360 trial for narcolepsy (a sleep disorder causing sudden sleep attacks) or idiopathic hypersomnia (excessive daytime sleepiness). Researchers want to see if continuing TAK-360 remains safe and effective for you.
Brandon, FloridaAges 18–71 - NCT07177352RecruitingPhase 3
Screening for Roche Alzheimer's studies
This is a screening study to find people who might be eligible for other Alzheimer's drug studies run by the same company. It helps match you to a treatment trial if you qualify.
Birmingham, AlabamaAges 50–90 - NCT07219966RecruitingPhase 3
Study of Brenipatide for alcohol use disorder
This trial tests an injectable medicine called brenipatide to help people with moderate-to-severe alcohol use disorder reduce or stop drinking. It is for adults who are motivated to change their drinking habits.
Birmingham, AlabamaAges 18–75 - NCT07755605Recruiting
Smartphone app training for social skills in schizophrenia
This trial tests a smartphone app designed to help people with schizophrenia or schizoaffective disorder improve their social thinking and interactions. It may be a good option if you can use an app and are on stable medication.
SeoulAges 19–60 - NCT07691918Enrolling by invitation
Brain stimulation for mild memory loss
This trial tests if a non-invasive brain stimulation technique can help people with mild memory problems. It uses a special cap to gently stimulate the brain and aims to improve thinking and memory.
Roanoke, VirginiaAges 55–80 - NCT07420816RecruitingPhase 2
Testing a new drug for insomnia
This trial tests a new medication, APSTZD, to see how well it works and how safe it is for people with insomnia, especially those who have trouble staying asleep through the night.
Bragança Paulista, São PauloAges 18–64 - NCT07402265Recruiting
Online support for suicidal thoughts in LGBTQ+ youth
This trial tests a brief online program for teens and young adults who identify as sexual or gender minorities and have had suicidal thoughts in the last 6 months. It aims to see if this virtual help can reduce those thoughts and make participants feel better.
London, OntarioAges 13–25 - NCT07304440RecruitingPhase 1/Phase 2
Stem cell and glutathione therapy study for children with autism
This study tests a combination of experimental treatments for children with autism spectrum disorder. It may help if your child has not had stem cell or glutathione therapy before.
Winter Park, FloridaAges 3–12 - NCT07610746Recruiting
Brain Blood Flow in Newborns Exposed to Opioids Before Birth
This study looks at how opioid exposure during pregnancy affects blood flow and brain function in newborns. Researchers will compare babies exposed to opioids in the womb with babies who were not exposed, to better understand how prenatal opioid exposure affects the developing brain.
Indianapolis, IndianaAges Up to 1 day - NCT07658898Recruiting
Brain stimulation for negative and cognitive symptoms in schizophrenia
This study tests a new type of brain stimulation called temporal interference to see if it can help with negative symptoms (like lack of motivation or emotion) and cognitive symptoms (like trouble with memory or focus) in schizophrenia. It uses a special head device to target a specific brain area.
ShanghaiAges 18–65 - NCT06136195RecruitingPhase 1
Mavoglurant for alcohol craving in heavy drinkers
This trial tests whether a medication called mavoglurant can reduce alcohol cravings and drinking in people who are heavy drinkers with alcohol use disorder and are not looking for treatment.
New Haven, ConnecticutAges 21–50 - NCT04278404Recruiting
Drug safety study for children already on certain medicines
This study measures how certain medicines move through the body and checks their safety in children. It may help doctors better understand dosing and side effects in kids who are already receiving these treatments, or in some kids who recently tested positive for COVID-19.
Phoenix, ArizonaAges birth–20 years - NCT07631598Recruiting
Buprenorphine at Needle Exchange Programs to Prevent Overdoses
This study tests whether offering buprenorphine (a medication that reduces cravings and withdrawal) directly at syringe service programs (places where people get clean needles) can help people with opioid addiction stay safe and reduce overdose risk. If you use opioids and visit a syringe service program, this may be an option to explore.
Los Angeles, CaliforniaAges 18 years+ - NCT06225011RecruitingPhase 1
Can a common antidepressant help your immune system fight colorectal cancer before surgery?
This trial is testing whether a common antidepressant called fluoxetine (Prozac) can help your immune system fight colorectal cancer before surgery. It's for people with early-stage colorectal cancer who have not yet had treatment.
Los Angeles, CaliforniaAges 18 years+
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 8,195 recruiting psychiatry studies from the U.S. registry right now, out of 13,258 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.