Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 8,195 recruiting studies in this area right now.
By phase
- Not applicable6,798
- Phase 2512
- Phase 1258
- Phase 3245
- Phase 4213
- Phase 1/Phase 298
- Phase 2/Phase 371
Top conditions
- Depression422
- Anxiety415
- Alzheimer Disease341
- Autism Spectrum Disorder258
- Dementia226
- Mild Cognitive Impairment199
- Schizophrenia192
- Major Depressive Disorder189
- Cognitive Impairment157
- Insomnia152
- Alcohol Use Disorder150
- Opioid Use Disorder145
- Stress136
- PTSD110
- Autism95
- Mental Health92
- Suicidal Ideation92
- Anxiety Disorders85
Leading sponsors
- VA Office of Research and Development103
- Yale University95
- Massachusetts General Hospital78
- Stanford University72
- Assistance Publique - Hôpitaux de Paris65
- Johns Hopkins University63
- University of California, Los Angeles61
- The University of Hong Kong52
- University of Pennsylvania51
- Karolinska Institutet50
Where studies are running
- California530
- New York268
- Massachusetts263
- Texas223
- Maryland176
- Pennsylvania175
- Florida153
- Alabama118
- Arizona117
- Connecticut113
Recruiting studies8,194 total
- NCT07774481Recruiting
Anxiety skills study for Ohio residents
This study tests an anxiety management program that you can use on your smartphone. It aims to help reduce anxiety symptoms and improve daily functioning.
Columbus, OhioAges 18 years+ - NCT07625280RecruitingPhase 3
Twice-nightly treatment for narcolepsy or idiopathic hypersomnia
This study tests whether taking the sleep medicine Xywav two times each night is safe and helps control symptoms better than a placebo. People with narcolepsy or idiopathic hypersomnia may join, including those who have not tried oxybate medicines before.
Los Angeles, CaliforniaAges 18–75 - NCT07217925Recruiting
Neurofeedback for people with OCD and PTSD symptoms
This study tests whether a brain training technique called neurofeedback can improve well-being in people who have both OCD and post-traumatic stress symptoms. It is for adults on a therapy waiting list who do not have other serious untreated conditions.
Detroit, MichiganAges 18–90 - NCT06898879Recruiting
Working together to improve mental health care for veterans
This study is for veterans getting mental health support through VA programs. It tests a way to improve teamwork between veterans and their care teams to make the care better.
San Diego, CaliforniaAges 18 years+ - NCT07772167Recruiting
Understanding stomach and gut symptoms in functional dyspepsia
This study uses brain scans (MRIs) and a test meal to understand how the brain and stomach communicate in people with functional dyspepsia (ongoing pain or fullness). This could help improve treatments by identifying how people with this condition feel and process stomach sensations differently.
Boston, MassachusettsAges 18–65 - NCT07732179Recruiting
Aromatherapy and music for nurse stress relief
This trial tests whether aromatherapy (using essential oils) and music can help reduce stress in nurses working in a cardiac care unit (CCU). If you are a CCU nurse, you may find this helpful for managing work-related stress.
Chicago, IllinoisAges 18 years+ - NCT06523439Recruiting
Brain stimulation for depression in young people
This study tests a new type of brain stimulation called accelerated intermittent theta burst stimulation (aiTBS) in young people (ages 13-20) with depression who have not tried many treatments before. The goal is to see if this treatment can safely help reduce depression symptoms.
Austin, TexasAges 13–20 - NCT07162909Recruiting
Mental health and crime risk study
This study looks at health records of people in Stockholm to see if there are warning signs before a crime. It compares people who had a special evaluation with those who didn't, to find patterns that could help prevent future crimes.
StockholmAges 18 years+ - NCT05473013Recruiting
Digital health tool for loss-of-control eating
This study tests a digital health tool designed to help you build skills to manage loss-of-control eating. If you qualify, you'll use the tool and complete assessments to see if it helps you gain better control.
Philadelphia, PennsylvaniaAges 18–70 - NCT06526078Recruiting
Combining brain training with ketamine for depression
This study tests if adding computer-based cognitive training to ketamine treatment can improve mood in people with depression that hasn't responded to other treatments. It aims to see if the combination works better than ketamine alone.
Oakland, CaliforniaAges 18–80 - NCT04373317RecruitingPhase 4
Comparing two medicines for hallucinations in Parkinson's disease
This study compares two drugs, pimavanserin and quetiapine, to see which works better for hallucinations or delusions caused by Parkinson's disease. The goal is to help patients manage these symptoms more effectively.
Tucson, ArizonaAges 40 years+ - NCT06093906Recruiting
Positive processes and transition to health (PATH) study
This study tests a new therapy that may help people recover after a stressful life event. Over about 6 weeks, you'll work with a coach to retrain your brain's patterns and feel more in control again, as well as reconnect with positive activities.
Newark, DelawareAges 18–65 - NCT06937229RecruitingPhase 3
Long-term study of KarXT for agitation in Alzheimer's
This trial tests if KarXT, taken with KarX-EC, is safe and effective for long-term treatment of agitation in Alzheimer's disease. It is for people who already completed a previous KarXT study.
Chandler, ArizonaAges 55–90 - NCT07392177RecruitingPhase 2
Understanding the brain's role in insomnia
This trial tests whether a part of the brain called the locus coeruleus is involved in insomnia. It involves sleep questionnaires and possibly brain imaging to understand your sleep problems better.
Macquarie Park, New South WalesAges 30–65 - NCT06898099Recruiting
Hypnotherapy for chronic insomnia in primary care
This study tests whether 4 short hypnotherapy sessions can help people with chronic insomnia. It is designed for adults who struggle with sleep for months and want a non-drug option in their regular doctor's office.
Bain-de-BretagneAges 18 years+ - NCT05868668Recruiting
Low-intensity shockwave versus wave therapy for erectile and pelvic pain
This trial compares two types of low-intensity wave therapy to see which works better for erectile dysfunction and/or chronic pelvic pain. Participants may benefit if these therapies improve erection quality and reduce pelvic pain.
Cleveland, OhioAges 40 years+ - NCT05372029Recruiting
Study of animal-assisted therapy for alcohol use disorder
This trial studies whether animal-assisted therapy can help Veterans with alcohol use disorder, especially early after quitting or reducing alcohol. It may help with cravings or staying stable, but you must meet specific health and safety requirements.
San Diego, CaliforniaAges 18–65 - NCT07770204Recruiting
Music during surgery for people with type 2 diabetes
This study tests whether listening to calming music before and during surgery can help reduce stress and improve recovery for people with type 2 diabetes. If you are scheduled for elective surgery and have type 2 diabetes, you may be able to join.
Istanbul, IstanbulAges 40–70 - NCT07549178Recruiting
Mobile monitoring and care coordination for serious mental illness
This study tests whether combining extra care coordination with tracking data from your smartphone can help improve mental health care and reduce hospital visits. Researchers will use your smartphone to monitor your wellbeing while a care coordinator helps connect you with the support you need.
West Los Angeles, CaliforniaAges 18 years+ - NCT07482345Recruiting
Fasting strategies and anxiety in children having surgery
This study looks at whether different fasting instructions before surgery can help children be more comfortable and less anxious. It involves children having groin or penis surgery and will check their stomach with ultrasound to see how fasting affects them.
Bursa, BursaAges 2–12 - NCT07101094Recruiting
Study on satisfaction with a new schizophrenia treatment
This study tracks how satisfied people with schizophrenia are with a new combination medicine called xanomeline and trospium chloride (XT). It aims to understand real-world experiences and benefits of this treatment.
Costa Mesa, CaliforniaAges 18 years+ - NCT07378644RecruitingPhase 2/Phase 3
Testing SKY-0515 for Huntington's disease
This trial tests a new drug called SKY-0515 in people with Huntington's disease. The goal is to see if it can safely improve symptoms or slow the disease down.
Englewood, ColoradoAges 25 years+ - NCT06044675RecruitingPhase 2
MDMA plus therapy for PTSD – a study with a partner
This study tests whether MDMA, combined with a type of talk therapy called CBCT (cognitive behavioral conjoint therapy), is more effective than CBCT alone for treating PTSD. You and a close partner will both participate in therapy sessions and take MDMA together.
Toronto, OntarioAges 18–80 - NCT07379827Recruiting
A study on switching to KarXT for schizophrenia
This trial looks at how well KarXT works and what side effects it might have when people with schizophrenia switch to it from their current antipsychotic medication. It may be an option for those who have started KarXT recently or who plan to switch from their current treatment.
Bryant, ArkansasAges 18 years+
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 8,195 recruiting psychiatry studies from the U.S. registry right now, out of 13,258 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.