Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 8,195 recruiting studies in this area right now.
By phase
- Not applicable6,798
- Phase 2512
- Phase 1258
- Phase 3245
- Phase 4213
- Phase 1/Phase 298
- Phase 2/Phase 371
Top conditions
- Depression422
- Anxiety415
- Alzheimer Disease341
- Autism Spectrum Disorder258
- Dementia226
- Mild Cognitive Impairment199
- Schizophrenia192
- Major Depressive Disorder189
- Cognitive Impairment157
- Insomnia152
- Alcohol Use Disorder150
- Opioid Use Disorder145
- Stress136
- PTSD110
- Autism95
- Mental Health92
- Suicidal Ideation92
- Anxiety Disorders85
Leading sponsors
- VA Office of Research and Development103
- Yale University95
- Massachusetts General Hospital78
- Stanford University72
- Assistance Publique - Hôpitaux de Paris65
- Johns Hopkins University63
- University of California, Los Angeles61
- The University of Hong Kong52
- University of Pennsylvania51
- Karolinska Institutet50
Where studies are running
- California530
- New York268
- Massachusetts263
- Texas223
- Maryland176
- Pennsylvania175
- Florida153
- Alabama118
- Arizona117
- Connecticut113
Recruiting studies8,194 total
- NCT06771856Recruiting
Stepped care for insomnia in chronic spinal pain
This trial tests a step-by-step approach to cognitive behavioral therapy for insomnia in people who also have chronic neck or back pain. It aims to see if treating sleep problems can help reduce pain and improve quality of life.
BrusselsAges 18–65 - NCT06523296Recruiting
Antibodies and thinking problems in myasthenia or Alzheimer's
This study looks at whether certain antibodies are linked to memory and thinking problems in people with myasthenia gravis or Alzheimer's disease. It involves a one-time use of leftover spinal fluid from a previous diagnostic test.
Nice, Alpes MaritimesAges 18 years+ - NCT07405775Recruiting
SleepFix for Youth: app-based insomnia therapy with psychologist support
This study tests a smartphone app that helps young people with insomnia develop better sleep habits, with guidance from an e-psychologist. It may help you sleep better without needing in-person therapy.
Sydney, New South WalesAges 16–24 - NCT06996652RecruitingPhase 2
Study of adalimumab to delay Parkinson's symptoms in sleep disorder
This trial tests whether adalimumab, an immune system drug, helps people with REM sleep behavior disorder (a condition that may warn of Parkinson's disease) stay healthy longer. Participants will receive injections of the drug or a placebo to see if it prevents Parkinson's-related brain problems.
Los Angeles, CaliforniaAges 50–80 - NCT07773883Enrolling by invitationPhase 3
Long-term safety of solriamfetol for ADHD in children and teens
This study checks the long-term safety of the drug solriamfetol for attention-deficit/hyperactivity disorder (ADHD) in children and adolescents who have already completed an earlier study of this medication.
Dothan, AlabamaAges 6–18 - NCT05527652Recruiting
Breathing tube device to help blocked upper airways in children
This study tests a self-supporting breathing tube placed through the nose during sleep to reduce upper airway blockage and improve breathing in children. It may help children who have sleep apnea symptoms, especially after tonsil/adenoid treatment or when tonsil removal isn’t possible.
Ann Arbor, MichiganAges 3–21 - NCT07650591Recruiting
Tapping and vibration to ease needle pain in children
This study tests whether rhythmic tapping and gentle vibration near the skin can help children ages 6–12 feel less pain and fear during blood draws. Researchers want to see if these simple techniques can make the procedure more comfortable.
Antalya, KepezAges 6–12 - NCT06788678Recruiting
Web-based moral elevation for veterans with PTSD
This trial tests a website designed to help veterans with PTSD feel inspired by stories of others' good deeds, which may reduce PTSD symptoms. You would complete sessions online and answer questions about your experiences.
Temple, TexasAges 18 years+ - NCT05790239RecruitingPhase 2
MDMA therapy sessions for veterans with PTSD
This Phase 2 trial tests whether therapy assisted by MDMA can reduce symptoms of moderate to severe post-traumatic stress disorder (PTSD) in eligible veterans. It includes supervised therapy sessions and extra study visits with video recording to track changes over time.
Los Angeles, CaliforniaAges 18 years+ - NCT07771322Recruiting
Online therapy for Asian American adults
This study tests a digital mental health platform designed for Asian Americans. You'll get online therapy sessions, and the goal is to see if the platform helps improve your mental health.
Brooklyn, New YorkAges 18–90 - NCT07219082Recruiting
Fentanyl safety education for people who use stimulants
This study is testing a program called BSAFE that teaches people who use stimulants like cocaine or methamphetamine how to stay safer around fentanyl. It aims to prevent accidental fentanyl exposure and its harms.
San Francisco, CaliforniaAges 18 years+ - NCT07771530RecruitingPhase 2
Medication or dog therapy for PTSD symptoms
This study tests whether a combination of two medications (reboxetine and Ritalin) is more effective than dog-assisted therapy for reducing PTSD symptoms. Participation involves either taking the medications or attending dog therapy sessions.
HaifaAges 18–70 - NCT06701903RecruitingPhase 2
Study of an investigational drug for generalized anxiety disorder
This study tests an investigational oral medication (ITI-1284) for people with moderate to severe generalized anxiety disorder (GAD) who haven't found enough relief from at least two standard medications. The goal is to see if this new drug helps reduce anxiety symptoms.
Birmingham, AlabamaAges 18 years+ - NCT07574060RecruitingPhase 2/Phase 3
Allopurinol as an Add-On Treatment for Depression
This trial tests whether allopurinol, a medication typically used for gout, might help reduce depression symptoms when added to standard depression treatment. Researchers believe it may work by reducing inflammation in the brain that contributes to depression.
TantaAges 18–60 - NCT07570654RecruitingPhase 2/Phase 3
Testing COMP360 for post-traumatic stress disorder
This study tests whether COMP360, a new treatment, can help people with PTSD feel better and cope with their symptoms. The research team will measure how safe it is and how well it works over time.
New York, New YorkAges 18 years+ - NCT07771335Recruiting
Erlangen stroke registry: tracking strokes over time
This study collects health information from people in Erlangen, Germany who have had a stroke. It helps researchers understand stroke causes and outcomes to improve future care.
ErlangenAges 18 years+ - NCT07654205Recruiting
Smartphone intervention for young adults with ADHD and heavy drinking
This study tests a smartphone-based intervention for young adults with ADHD who also drink heavily. It aims to help manage both conditions together. You may qualify if you are 18-25, have ADHD (combined type), drink heavily on a weekly basis, own a smartphone, and can read English.
Pittsburgh, PennsylvaniaAges 18–25 - NCT07771036Recruiting
Brain stimulation to improve memory and balance in older adults
This study tests a non-invasive brain stimulation technique called temporal interference stimulation to see if it can improve memory and balance during daily activities in older adults with mild cognitive impairment. The goal is to find a safe, drug-free way to support brain health.
Shanghai, Shanghai MunicipalityAges 65 years+ - NCT05541276RecruitingPhase 3
Melatonin to prevent waking confusion in young children after surgery
This study tests whether giving melatonin before surgery can help prevent agitation and confusion in young children after they wake up from anesthesia. Participation may help your child have a smoother recovery after their procedure.
Copenhagen, Capital RegionAges 1–6 - NCT07489651RecruitingPhase 2
New treatment for generalized anxiety disorder
This trial tests a new medication called RE104 for people with generalized anxiety disorder (GAD). The goal is to see if it helps reduce anxiety symptoms safely.
Birmingham, AlabamaAges 18–74 - NCT07606248Recruiting
Virtual forest mindfulness for pregnant women's mental health
This study tests whether using virtual reality to explore a calming digital forest helps reduce stress and improve mood during pregnancy. You'd use a VR headset a few times to practice mindfulness (focused breathing and relaxation) and complete short surveys about how you're feeling.
HsinchuAges 18 years+ - NCT07726875Enrolling by invitation
Orexin and confusion after surgery in older adults
This study looks at a brain chemical called orexin (which helps control wakefulness) in older adults after surgery. The goal is to see if orexin levels are linked to confusion or agitation that can happen when waking up from anesthesia. If you take part, your blood will be tested before and after surgery.
Shanghai, Shanghai MunicipalityAges 60 years+ - NCT06935604Recruiting
Mindfulness VR for hospital patients
This trial tests whether a virtual reality (VR) program with calming mindfulness activities can help hospitalized patients feel less stressed and more at ease. It is designed for adults who are stable enough to be in a hospital and can use simple VR equipment.
Palo Alto, CaliforniaAges 18–99 - NCT04789746Enrolling by invitation
Physical fitness program for children with mobility challenges
This study tests a physical fitness program designed for children who have mobility challenges due to conditions like cerebral palsy. The program aims to improve fitness and overall well-being in a safe and supportive environment.
Chicago Heights, IllinoisAges 6–18
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 8,195 recruiting psychiatry studies from the U.S. registry right now, out of 13,258 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.