Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,770 recruiting studies in this area right now.
By phase
- Not applicable6,416
- Phase 2492
- Phase 1248
- Phase 3239
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety388
- Depression381
- Alzheimer Disease338
- Autism Spectrum Disorder240
- Dementia226
- Mild Cognitive Impairment195
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder144
- Opioid Use Disorder142
- Stress117
- PTSD105
- Mental Health98
- Autism94
- Mild Cognitive Impairment (MCI)88
- Suicidal Ideation88
Leading sponsors
- VA Office of Research and Development105
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University61
- University of California, Los Angeles58
- University of Pennsylvania53
- The University of Hong Kong51
- Karolinska Institutet50
Where studies are running
- California517
- Massachusetts266
- New York256
- Texas209
- Maryland175
- Pennsylvania171
- Florida149
- Alabama118
- Arizona108
- Illinois104
Recruiting studies7,770 total
- NCT07146438Recruiting
TMS and therapy for obsessive-compulsive disorder
This study tests whether combining brain stimulation (rTMS) with talk therapy can help people with OCD. It involves daily visits for 6 weeks and is for those who have already tried ERP therapy and SRI medication.
Los Angeles, CaliforniaAges 18 years+ - NCT07146373Recruiting
Breathing muscle training and thinking ability study
This trial tests whether training the muscles you use to breathe in can help improve thinking and memory. It's for people with mild to moderate cognitive changes who are on stable medication.
Aigáleo, AtticaAges 60–90 - NCT07145697RecruitingPhase 4
EEG study of anesthesia and consciousness in epilepsy
This trial tests how anesthesia affects brain activity in people with drug-resistant epilepsy who need brain electrode monitoring. It may help us understand consciousness and improve anesthesia safety.
Guangzhou, GuangdongAges 3–65 - NCT07146269Enrolling by invitation
Virtual reality and brain stimulation for depression
This study tests if combining virtual reality with a gentle brain stimulation method at home can help people with major depression. You would use a headset and small electrodes to receive treatment in your own home.
MunichAges 18–65 - NCT07145866RecruitingPhase 4
Varenicline and TMS for quitting nicotine use
This study tests whether combining the medication varenicline (Chantix) with a special brain stimulation treatment (TMS) can help people quit vaping or smoking nicotine. If you're motivated to quit and use nicotine daily, you may be able to join.
Boston, MassachusettsAges 18–65 - NCT07151365Recruiting
Plant-based diets and healthy aging study
This study looks at how a plant-based diet might help people age in a healthy way. It is for adults 40 and older who are part of the Tzu Chi Foundation and are joining a health checkup program.
Dalin, ChiayiAges 40 years+ - NCT07146633Recruiting
Testing an EMDR app for PTSD and substance use
This study tests an app that uses EMDR therapy to help people with both PTSD and substance use problems. EMDR is a type of therapy that uses eye movements or taps to help process traumatic memories. You would use the app at home and avoid starting other new therapies during the study.
Toronto, OntarioAges 18 years+ - NCT07147205Recruiting
Meaning-centered group therapy for cancer patients
This trial tests whether a special type of group therapy, called meaning-centered group psychotherapy, helps people with cancer find purpose and meaning. It is offered through the Integrative Medicine Clinic and uses video calls so you can join from home.
Houston, TexasAges 18 years+ - NCT07145593Enrolling by invitation
Gamma tACS for ADHD: A non-invasive brain stimulation study
This trial tests whether a gentle brain stimulation technique called transcranial alternating current stimulation (tACS) can help people with ADHD. You would receive the stimulation while doing attention tasks, and the results could show if it improves symptoms.
IstanbulAges 18–40 - NCT07148258Recruiting
Georgia early intervention program study for providers and families
This study looks at how well Georgia's early intervention system works for babies and toddlers with developmental delays. Providers and caregivers will share their experiences to help improve services.
Atlanta, GeorgiaAges Any age - NCT07153549Recruiting
Biolizin for improving poor appetite in children aged 6 to 36 months
This trial tests whether a supplement called Biolizin can help improve appetite in young children who have had a poor appetite for 2 weeks or more. It's for children who are otherwise healthy and growing normally.
Haiphong, Hai PhongAges 6 months–3 years - NCT07148232RecruitingPhase 4
Helping people experiencing homelessness quit smoking
This study tests an extended program to help people who are homeless and smoke at least 5 cigarettes a day quit smoking. It provides nicotine replacement therapy (like patches or gum) and support over time.
San Francisco, CaliforniaAges 18 years+ - NCT07151846Enrolling by invitation
Using phone data to predict depression
This study uses your smartphone and a Fitbit to track mood patterns and see if they can predict depression. You may join as someone with a mood disorder, as a healthy volunteer, or as someone at higher risk for mood problems.
Seoul, Seongbuk-guAges 19–75 - NCT07153848Recruiting
Lecanemab treatment for early Alzheimer's disease
This study tests how lecanemab works in people with early Alzheimer’s, including those with mild dementia or mild memory problems. It aims to see if the drug can help clear brain plaques and slow down symptoms.
Hangzhou, ZhejiangAges 45–85 - NCT07146503Recruiting
Esketamine Nasal Spray for Treatment-Resistant Depression in Real Life
This study tests esketamine nasal spray (a fast-acting antidepressant) for people with treatment-resistant depression who haven't gotten better after trying at least two other antidepressants. It looks at how well the spray works in everyday doctor's offices, not just in research clinics.
Genova, GeAges 18–74 - NCT06958341Recruiting
Brain and nerve disease registry with optional fluid collection
This study collects extra fluid from a spinal tap to learn more about brain and nerve diseases. It may help find better treatments in the future.
Berlin, State of BerlinAges Any age - NCT06959069Recruiting
Intermittent Fasting, Sleep, and Quality of Life Study
This study tests whether intermittent fasting can improve sleep and quality of life in healthy adults. If you are generally healthy and not on specific medications or diets, you may be able to join.
BrusselsAges 18–65 - NCT06958692RecruitingPhase 3
Testing a new antidepressant combination for depression
This study tests a new combination of two medications (dextromethorphan and bupropion) as a treatment for major depressive disorder. It may be an option if you have not already tried many antidepressants that didn't work.
Beijing, Beijing MunicipalityAges 18–65 - NCT06136546RecruitingPhase 2
Infliximab for depression with cognitive problems
This trial tests if a medicine called infliximab, given through an IV, can help improve thinking and memory problems in people with moderate to severe depression who also have high inflammation levels. It aims to see if lowering inflammation can ease both mood and cognitive symptoms.
Boston, MassachusettsAges 25–50 - NCT07141394Enrolling by invitation
Supporting recovery for homeless veterans in VA housing
This trial helps homeless veterans in VA supportive housing get coordinated access to addiction recovery services. It aims to improve equity and outcomes for those in recovery.
West Los Angeles, CaliforniaAges Any age - NCT07142278RecruitingPhase 1
Alzheimer's vaccine study for healthy adults ages 40 to 65
This trial tests an experimental vaccine (DUVAX) that targets two proteins linked to Alzheimer's disease: amyloid-beta and tau. It is an early-stage study to check safety and see how the body responds, aiming to prevent or delay the disease.
Miami Lakes, FloridaAges 40–65 - NCT07140913RecruitingPhase 3
Testing KarXT for bipolar I mania with mood stabilizers
This study tests whether adding KarXT to lithium, valproate, or lamotrigine helps calm manic episodes in people with bipolar I disorder. It aims to see if the combination is safe and works better than the mood stabilizer alone.
Bentonville, ArkansasAges 18–65 - NCT07136948Recruiting
Mindfulness plus body-sensor training for stress relief
This study tests whether mindfulness training paired with a special shirt that tracks your breathing and heart rate can help reduce stress. You'll be assigned to one of two groups and give feedback on your experience.
Pittsburgh, PennsylvaniaAges 18–30 - NCT07142954RecruitingPhase 3
Alzheimer's research study for healthy people
This study is looking at healthy people with no memory concerns to better understand early signs of Alzheimer's disease. You would provide samples and do thinking tests, but you won't take any experimental medicines.
Houston, TexasAges 55–75
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,770 recruiting psychiatry studies from the U.S. registry right now, out of 12,391 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.