Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,780 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1251
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease339
- Autism Spectrum Disorder240
- Dementia227
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder142
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Suicidal Ideation89
- Mild Cognitive Impairment (MCI)88
Leading sponsors
- VA Office of Research and Development105
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- The University of Hong Kong51
- Karolinska Institutet50
Where studies are running
- California520
- Massachusetts267
- New York256
- Texas209
- Maryland176
- Pennsylvania171
- Florida149
- Alabama118
- Arizona108
- Illinois104
Recruiting studies7,780 total
- NCT06990191Recruiting
Partner-assisted PTSD therapy study for veterans
This study tests whether having your partner help you with a type of talk therapy (prolonged exposure) can improve your PTSD symptoms more than doing the therapy alone. It is designed for veterans in a steady relationship whose partner does not have PTSD.
Phoenix, ArizonaAges 18 years+ - NCT06982820Recruiting
Brain training therapy for depression with loss of interest
This trial tests a new type of brain training (self-neuromodulation) to help people with major depression who also have a significant loss of interest or pleasure (anhedonia). If you qualify, you may get a non-invasive treatment that uses real-time brain feedback to improve symptoms.
Providence, Rhode IslandAges 22–75 - NCT06989476Enrolling by invitation
Helping families get support through child checkups
This study looks at how to improve screenings that check how children ages 0-5 and their families are doing emotionally and socially. It aims to make it easier for families to get connected with helpful services.
Denver, ColoradoAges 18 years+ - NCT06985927Recruiting
Self-Concept and Memory in Alcohol Use Disorder
This study looks at how people with alcohol use disorder remember their past and see themselves. Researchers will ask about your memories and self-image to understand the link between alcohol and thinking patterns.
ReimsAges 24 years+ - NCT06989138Recruiting
Brace and exercise for spondylolisthesis
This trial tests if wearing a back brace combined with exercise helps people with a specific type of low back problem called spondylolisthesis (where a spine bone slips forward). It may reduce pain and improve function.
Istanbul, IstanbulAges 18–65 - NCT06991166Recruiting
A therapy study for new mothers with depression whose baby is in the NICU
This study tests a new talk therapy program to help new mothers with depression whose babies are in the neonatal intensive care unit (NICU). You may join if you gave birth in the last year and have signs of depression, like a diagnosis or certain feelings.
Hackensack, New JerseyAges 18 years+ - NCT06989398Recruiting
ASCEND supervisor training for Dutch small businesses
This trial tests a training program for supervisors in Dutch companies with 10–250 employees. It aims to improve supervisor skills and employee well-being.
AmsterdamAges 18 years+ - NCT06988787Recruiting
Resilience therapy for veterans after trauma
This study tests a program to help female veterans who have experienced intimate partner violence or military sexual trauma and have stress symptoms. It aims to improve emotional well-being and resilience.
Houston, TexasAges 18 years+ - NCT06989853RecruitingEarly Phase 1
Testing troriluzole for methamphetamine use disorder
This study tests whether a medication called troriluzole can help people who use methamphetamine. If you have methamphetamine use disorder and are not seeking treatment right now, this study may be an option for you.
Lexington, KentuckyAges 18–55 - NCT06985784Recruiting
Virtual reality for head and neck cancer patients and caregivers
This study tests whether using virtual reality can help reduce depression, anxiety, and pain in people with head and neck cancer and their caregivers. You and your caregiver may be able to use VR headsets together as part of your treatment.
Duarte, CaliforniaAges 18 years+ - NCT06984809Recruiting
Invest in Play: a parent program for children with behavior problems
This study tests a new program called 'Invest in Play' that helps parents of children with behavior problems. The goal is to see if learning new ways to play and interact with your child can improve their behavior.
Bergen, FyllingdalenAges 18 years+ - NCT06992804RecruitingEarly Phase 1
Light therapy and lecanemab for mild Alzheimer's
This trial tests whether a special near-infrared light device, combined with the medication lecanemab, can help people with mild Alzheimer's disease. It aims to see if the light therapy can slow down memory loss and improve daily function.
BeijingAges 50–90 - NCT06983080RecruitingPhase 2
Trazodone for better sleep in older adults
This study tests whether trazodone, a sleep medication, improves insomnia in people 65 and older. You might benefit if you struggle with falling or staying asleep and are not already taking other sleep aids.
Montreal, QuebecAges 65 years+ - NCT06983769Recruiting
CPAP vs Mouthpiece for Sleep Apnea in Patients with Memory Issues
This study compares two treatments for sleep apnea (CPAP and a custom mouthpiece) to see which is better for patients who also have mild memory or thinking problems. Sleep apnea is a condition where breathing stops and starts during sleep. You may qualify if you have moderate-to-severe sleep apnea and mild cognitive impairment.
Kent Ridge, Please SelectAges 45 years+ - NCT06983275Recruiting
Can vibrations help you fall asleep faster?
This study tests if a vibration-based intervention can improve sleep for people with chronic insomnia who have trouble falling asleep. It aims to help without using medication or therapy.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06989957RecruitingPhase 1
Psilocybin and MDMA therapy for PTSD in veterans
This study tests whether a combination of two investigational drugs, psilocybin and MDMA, can help veterans with post-traumatic stress disorder (PTSD). You would receive the drugs in a controlled setting and be monitored closely.
Baltimore, MarylandAges 21 years+ - NCT06991062Recruiting
Brain stimulation and smoking: finding personalized treatments
This study tests whether a non-invasive brain stimulation technique (rTMS) can help people who smoke reduce cravings or change smoking behavior. You'll also have your brain activity recorded with a cap (EEG) and do some vaping tasks.
Houston, TexasAges 21–60 - NCT06983405Recruiting
Physical therapy for depression and quality of life pilot
This study is testing whether adding physical therapy to your usual depression care can improve your quality of life while you are in the hospital. If you are an adult admitted to the psychiatry unit with major depression, you may be able to join.
Zaragoza, AragonAges 18 years+ - NCT06986460RecruitingPhase 3
Low-frequency TMS for bipolar depression
This study tests whether low-frequency TMS (a gentle magnetic stimulation to a specific part of the brain) can help treat depression in people with bipolar disorder who did not get enough benefit from a previous study. You must be on a mood stabilizer and not taking certain anticonvulsant medications.
Toronto, OntarioAges 18 years+ - NCT06984757Enrolling by invitation
Brain waves and thinking in Parkinson's disease
This study looks at how brain activity relates to thinking and memory in people with Parkinson's disease, including those with and without cognitive issues, and those with deep brain stimulation. It uses EEG (a non-invasive brain wave recording) and sometimes mild brain stimulation (TMS or tACS) to understand these connections better.
Iowa City, IowaAges 18–99 - NCT06986122Recruiting
Testing virtual reality to help with pain
This study tests whether virtual reality can help change how you feel pain. You'll be asked to complete tasks and rate your experience.
Hanover, New HampshireAges 18–55 - NCT06989593Recruiting
Storytelling study for parents of children with urogenital conditions
This study tests whether guided journaling (writing or dictating stories) can help parents cope and connect. It involves a 5-week journaling activity and one follow-up interview.
Boston, MassachusettsAges 18 years+ - NCT06992895Recruiting
Hologram for pain and fear during burn dressing changes in children
This trial tests whether watching a hologram during burn dressing changes can reduce pain, anxiety, and fear in children. It may help make the experience less stressful for kids aged 3 to 12 with small, second-degree burns.
Erzurum, YakutiyeAges 3–12 - NCT06986863Recruiting
Digital snapshot to reduce restraint use in ER
This study tests using a special digital picture or video (a 'snapshot') to help Emergency Department staff understand and care for people with intellectual or developmental disabilities. The goal is to reduce the use of restraints and make the visit a better experience for you or your loved one.
New Hyde Park, New YorkAges 18 years+
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,780 recruiting psychiatry studies from the U.S. registry right now, out of 12,430 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.