Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,780 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1251
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease339
- Autism Spectrum Disorder240
- Dementia227
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder142
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Suicidal Ideation89
- Mild Cognitive Impairment (MCI)88
Leading sponsors
- VA Office of Research and Development105
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- The University of Hong Kong51
- Karolinska Institutet50
Where studies are running
- California520
- Massachusetts267
- New York256
- Texas209
- Maryland176
- Pennsylvania171
- Florida149
- Alabama118
- Arizona108
- Illinois104
Recruiting studies7,780 total
- NCT05866107Recruiting
App and smart scale program for weight loss in bipolar or schizophrenia
This study tests whether using a health app and smart body-fat scales helps people who are overweight or obese lose weight. It is designed for adults with bipolar disorder or schizophrenia who are stable and can safely follow the weight-loss and activity plan.
Beijing, Beijing MunicipalityAges 18–60 - NCT04366518RecruitingEarly Phase 1
Personalized brain-based treatment for frequent voice hallucinations
This early-phase study tests a personalized treatment plan for people who hear voices (auditory verbal hallucinations) at least weekly. It uses brain/machine-based information to try to better target hallucinations and monitor safety.
New Haven, ConnecticutAges 18–65 - NCT04935164Recruiting
Study of gender dysphoria versus a control group
This study compares people with gender dysphoria to people without it. It looks at differences in symptoms or outcomes and may help researchers better understand how gender dysphoria affects mental well-being.
PoitiersAges 18–60 - NCT06017713Recruiting
Brain stimulation plus exposure for stubborn OCD
This trial tests whether a gentle brain stimulation (tDCS) combined with facing your fears can help people with hard-to-treat OCD. If you've tried multiple treatments without relief, this study may offer a new option.
PoitiersAges 18–70 - NCT06009523Recruiting
Testing brain stimulation for suicidal thoughts
This study tests a non-invasive brain stimulation technique called tDCS, which uses mild electrical currents to reduce suicidal thoughts in people with depression. If you have moderate to severe depression and still have suicidal ideation despite treatment, this might be an option.
Faye-l'AbbesseAges 18 years+ - NCT06827678Recruiting
Study of Alzheimer’s disease using brain scans in China
This study uses brain imaging to understand early changes in Alzheimer's disease. It may help people with or without memory problems learn more about their condition and support future treatments.
ShanghaiAges 45–90 - NCT06791551Recruiting
Non-drug therapy before heart surgery to protect the brain
This study tests whether a simple, non-drug, non-surgical program before heart surgery can help protect your brain. It is for people with heart disease who are at higher risk for problems like stroke after surgery.
Beijing, Beijing MunicipalityAges 18–80 - NCT06910605Recruiting
Driving simulator study for ADHD patients on drug holidays
This study uses a driving simulator to see how ADHD patients’ driving changes when they take a break from their stimulant medication (drug holiday). It may help explain how medication affects driving performance.
Zurich, ZRHAges 10 years+ - NCT06921499Recruiting
Sports-based mental health help for Karenni boys and men
This trial tests a sports program designed to improve mental health for Karenni refugee boys and men who live in North Carolina's Piedmont Triad area. Participants will join practices and activities that use sports to build well-being.
Winston-Salem, North CarolinaAges 8 years+ - NCT06982183RecruitingPhase 4
Propranolol and hydrocortisone effects on military performance
This trial studies how two medications—propranolol (a beta blocker often used for anxiety) and hydrocortisone (a steroid)—affect performance on military tasks. It aims to understand if these drugs help or hinder how soldiers perform under stress.
Silver Spring, MarylandAges 18–40 - NCT06976216RecruitingPhase 3
Study of KarXT plus KarX-EC for Alzheimer's cognitive symptoms
This trial tests a new combination treatment (KarXT plus KarX-EC) to see if it can help with thinking and memory problems caused by Alzheimer's disease. It is for people with mild to moderate Alzheimer's who have a caregiver available.
Long Beach, CaliforniaAges 60–85 - NCT06976697Recruiting
Home-based tDCS for major depression
This trial tests a home-use device that sends a small electrical current to the brain to treat major depression. It may be a good option if you are already on antidepressant medication and have a smartphone.
Boston, MassachusettsAges 22–70 - NCT06976203RecruitingPhase 3
Testing karxt for thinking problems in alzheimer's
This trial tests if a combination medicine, KarXT plus KarX-EC, can help with thinking and memory problems in people with mild to moderate Alzheimer's disease. It aims to see if the treatment is safe and effective.
Fullerton, CaliforniaAges 60–85 - NCT06429124Recruiting
Time-restricted eating for mild cognitive impairment
This trial tests whether a time-restricted eating schedule (eating only during certain hours of the day) can help people with mild cognitive impairment (MCI) or early Alzheimer’s disease. It is a lifestyle study that can be done mostly from home with a computer or smartphone.
Phoenix, ArizonaAges 55–89 - NCT06728774Recruiting
Cognitive rehab for veterans with depression and memory problems
This trial tests a cognitive rehabilitation program for veterans who have depression (MDD) and are experiencing trouble with memory, attention, or thinking. The goal is to see if the program can improve these cognitive issues.
Portland, OregonAges 18 years+ - NCT06868303Recruiting
Mental wellness hubs for young people in Hong Kong
This trial studies whether mental wellness youth hubs help young people feel better. You will be part of either a hub user group, a community group, or an eClinic group to see how the services affect your well-being.
Hong KongAges 12–24 - NCT06974838Recruiting
Theta burst stimulation for emotion regulation in autism
This trial tests a type of brain stimulation called theta burst stimulation to see if it helps people with autism who have limited verbal skills or intellectual disability manage their emotions better. It may offer a new way to support emotional well-being.
TaoyuanAges 8–30 - NCT06976528Recruiting
Relationship conflict and heavy drinking in young couples
This study looks at how romantic relationship conflicts and stress relate to heavy drinking in young adults. It involves a lab visit where you may be given alcohol and answer questions about your relationship and drinking habits.
New York, New YorkAges 21–29 - NCT06979258Recruiting
Heat relief study for low-income homes in Bangladesh
This study tests ways to cool homes with corrugated iron roofs and walls in urban Bangladesh. It aims to help residents who don't have air conditioning or certain health conditions.
Dhaka, Dhaka DivisionAges Any age - NCT06973759Recruiting
Bright light therapy for teens with depression who are night owls
This study tests whether bright light therapy in the morning can help Chinese teenagers with depression who tend to stay up late and feel more energetic in the evening. It aims to see if adjusting your body clock with light can improve mood.
Hong Kong, Hong KongAges 12–19 - NCT06980636RecruitingPhase 4
Shengmai liquid for long covid fatigue trial
This trial tests if a traditional Chinese medicine, Shengmai Liquid, can help reduce fatigue in people with long COVID. It is for adults aged 18 to 75 who feel tired for a long time after a COVID infection.
Beijing, ChinaAges 18–75 - NCT06976840Recruiting
Rapid antidepressant effects of new brain stimulation methods
This trial tests whether two types of non-invasive brain stimulation can quickly improve depression symptoms. It may be an option for adults with major depression who are not currently taking psychiatric medication.
Pittsburgh, PennsylvaniaAges 18–55 - NCT06975020Recruiting
Comparing biomarkers in regular cannabis users vs. non-users
This study compares biological markers between people who use cannabis regularly and those who do not, to understand how cannabis affects the body.
BaselAges 18–65 - NCT06981585Recruiting
Physical effects in children with chronic kidney failure
This study looks at physical changes in children with chronic kidney failure compared to healthy children. If you join, you will have some physical measurements taken to help doctors understand how kidney disease affects the body.
IzmirAges 8–18
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,780 recruiting psychiatry studies from the U.S. registry right now, out of 12,430 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.