Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,780 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1251
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease339
- Autism Spectrum Disorder240
- Dementia227
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder142
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Suicidal Ideation89
- Mild Cognitive Impairment (MCI)88
Leading sponsors
- VA Office of Research and Development105
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- The University of Hong Kong51
- Karolinska Institutet50
Where studies are running
- California520
- Massachusetts267
- New York256
- Texas209
- Maryland176
- Pennsylvania171
- Florida149
- Alabama118
- Arizona108
- Illinois104
Recruiting studies7,780 total
- NCT06944847Recruiting
Vaping and smoking study for people with schizophrenia
This study looks at habits of vaping and smoking in people with schizophrenia. It may help researchers understand how to better support people who want to reduce or quit nicotine use.
Buffalo, New YorkAges 21–50 - NCT06943859RecruitingPhase 2
Ketamine for opioid use disorder
This study tests whether ketamine, when added to methadone treatment, helps reduce opioid use and cravings. It is for adults with opioid use disorder who are already in a methadone program and have had recent cravings or illicit use. The trial involves multiple visits and follow-up assessments.
Baltimore, MarylandAges 18–65 - NCT06943573RecruitingPhase 2
Psilocybin therapy for bipolar ii depression
This study tests whether a psychedelic drug called psilocybin (the active ingredient in 'magic' mushrooms), combined with therapy, can help relieve depression in people with bipolar II disorder who haven't gotten better with other treatments. You'll receive the drug in a supervised setting and attend follow-up visits to see how it affects your mood.
Vancouver, British ColumbiaAges 19–65 - NCT06937541Recruiting
Family support in dementia mental health wards
This study is about improving care for people with dementia in mental health hospital wards. Researchers want to hear from family carers, people with dementia themselves, and staff to understand experiences and design better support.
LondonAges Any age - NCT06947941RecruitingPhase 3
Testing karxt for psychosis in alzheimer's disease
This study tests whether a new medicine called KarXT can help with psychosis (hallucinations or delusions) in people with Alzheimer's disease. It aims to reduce troubling symptoms while being safe for older adults.
Gilbert, ArizonaAges 55–90 - NCT06035211Recruiting
Can a 3D model of your kidney reduce anxiety before surgery?
This study tests whether showing you a personalized 3D model of your kidney before surgery helps lower anxiety. You'll be scheduled for a partial nephrectomy (removing just the tumor, not the whole kidney) for a kidney tumor.
AngersAges 18 years+ - NCT05922137Recruiting
ORIENT diet for brain blood vessel narrowing
This trial studies whether a specific dietary program (the ORIENT diet) can improve brain-related thinking and memory in people with narrowed brain or neck arteries. You may be able to help test whether the diet is safe and beneficial alongside usual care, through repeated assessments over time.
Hangzhou, ZhejiangAges 40 years+ - NCT06715852Recruiting
Moving on! Anxiety treatment in primary care
This study in Swedish primary care tests a tailored treatment program (including exercise) for people with anxiety disorders. It aims to see if this approach helps reduce anxiety better than usual care.
GothenburgAges 18–65 - NCT06937229RecruitingPhase 3
Long-term study of KarXT for agitation in Alzheimer's
This trial tests if KarXT, taken with KarX-EC, is safe and effective for long-term treatment of agitation in Alzheimer's disease. It is for people who already completed a previous KarXT study.
Chandler, ArizonaAges 55–90 - NCT06937892Recruiting
Metacognitive therapy vs. Cognitive therapy for anxiety
This study compares two different types of therapy for anxiety disorders: metacognitive therapy (which focuses on how you think about your thoughts) versus cognitive-behavioral therapy (which works on changing thoughts and behaviors). It may help you find which approach works best for you.
StockholmAges 18 years+ - NCT06941324Recruiting
Therapy to help teens and young adults with cancer feel better
This study tests a short-term therapy called Solution-Focused Brief Therapy to help teens and young adults with cancer reduce emotional distress. It's designed for people who are currently in treatment or have finished treatment within the last 5 years.
Ann Arbor, MichiganAges 15–39 - NCT06937606Enrolling by invitation
Reducing caregiver fatigue in cancer support group leaders
This study tests whether a mindfulness program can reduce stress and fatigue for group leaders who run support groups for women with cancer. If you lead such a group, you may benefit from learning ways to take better care of yourself.
Würzburg, BavariaAges 18 years+ - NCT06938841Recruiting
Maintenance rTMS for depression
This study tests whether ongoing rTMS treatments can help people who already improved after an initial round of rTMS for depression. It aims to keep the benefits going and prevent relapse.
San Diego, CaliforniaAges 18–80 - NCT06933095Recruiting
DHA supplement study for older adults with mild memory concerns
This study tests whether a DHA (omega-3) supplement can improve delivery of certain brain fats in older adults who have mild memory concerns. It involves taking a daily supplement and may include a lumbar puncture (spinal tap).
Cincinnati, OhioAges 55–82 - NCT06932120Recruiting
Online grief support for prolonged grief disorder
This study tests a technology-based program to help people with prolonged grief disorder (intense, long-lasting grief after a loss). You would use a computer and smartphone to complete activities and get support, all in Spanish.
Castellon, Castellón de La PlanaAges 18 years+ - NCT06933212Recruiting
Mediterranean diet for CADASIL and CAA
This trial is testing whether a Mediterranean diet (rich in fruits, vegetables, whole grains, and healthy fats) can help people with CADASIL or cerebral amyloid angiopathy (CAA) — two conditions that affect blood vessels in the brain. If you have one of these diagnoses, the study may help you understand how diet can support your brain health.
MilanAges 18 years+ - NCT06938763RecruitingPhase 1
Safety study of J4 in healthy volunteers
This trial tests a new drug called J4 in healthy adults to see if it is safe and how the body processes it. Healthy volunteers aged 18 to 64 may join to help researchers learn about the drug's effects.
TaipeiAges 18–64 - NCT06940674RecruitingPhase 3
CBD plus opioid treatment for recovery
This study tests whether adding cannabidiol (CBD) to your usual methadone or buprenorphine treatment helps you recover from opioid use disorder. If you're already in stable treatment with those medications, the trial aims to see if CBD can improve your outcomes.
New York, New YorkAges 18–65 - NCT06937021Enrolling by invitation
Art and philosophy program for kids' eco-anxiety
This trial tests whether an art and philosophy program can help elementary school children manage their eco-anxiety. If your child is in elementary school, they may be able to join.
Henhurst Ridge, Burton-on-TrentAges 5–12 - NCT06934759Enrolling by invitation
Parents' experience of a child with a large birthmark
This study explores how parents feel and cope when their child has a large congenital melanocytic nevus, a type of birthmark. You would take part in a one-on-one interview to share your experience.
Nancy, FranceAges 18 years+ - NCT06939088RecruitingPhase 2
Tirzepatide for alcohol reduction in schizophrenia
This trial tests if tirzepatide, a once-weekly injection, can help reduce heavy drinking in people who have both schizophrenia and alcohol use disorder. If you struggle with alcohol and have stable schizophrenia, this study may offer a new treatment option.
Aalborg, DenmarkAges 18–70 - NCT06935604Recruiting
Mindfulness VR for hospital patients
This trial tests whether a virtual reality (VR) program with calming mindfulness activities can help hospitalized patients feel less stressed and more at ease. It is designed for adults who are stable enough to be in a hospital and can use simple VR equipment.
Palo Alto, CaliforniaAges 18–99 - NCT06941428Recruiting
Redesigning trauma therapy for schools
This study is redesigning a trauma-focused therapy (TF-CBT) for schools. It tests a new version of the therapy to help students aged 7–19 who have experienced trauma and still feel upset by it.
Seattle, WashingtonAges 7 years+ - NCT06939426Recruiting
Music therapy for emergency department staff
This study tests whether listening to music and participating in music therapy can help healthcare workers in the emergency department feel less stressed and more humanized at work. It's a four-week program with eight sessions just for nursing staff.
Bogotá, Bogota D.C.Ages Any age
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,780 recruiting psychiatry studies from the U.S. registry right now, out of 12,430 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.