Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,780 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1251
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease339
- Autism Spectrum Disorder240
- Dementia227
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder142
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Suicidal Ideation89
- Mild Cognitive Impairment (MCI)88
Leading sponsors
- VA Office of Research and Development105
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- The University of Hong Kong51
- Karolinska Institutet50
Where studies are running
- California520
- Massachusetts267
- New York256
- Texas209
- Maryland176
- Pennsylvania171
- Florida149
- Alabama118
- Arizona108
- Illinois104
Recruiting studies7,780 total
- NCT06891716RecruitingEarly Phase 1
PET scan for TDP-43 proteinopathies
This study tests a new PET scan dye that may help see TDP-43 protein buildup in the brain, which is linked to certain dementias and ALS. It aims to improve diagnosis and tracking of these conditions.
AmsterdamAges 40–70 - NCT06522243Recruiting
Mindful parenting for parents of teens with special needs
This trial explores a mindful parenting program designed for parents or caregivers of teenagers with special educational needs. It aims to help reduce stress and improve family relationships.
Hong KongAges 18 years+ - NCT05649514Recruiting
Studying sleep problems in early Alzheimer’s risk patients
This study looks at sleep problems in people with mild Alzheimer’s disease and whether sleep measurements and questionnaires can help researchers understand early changes. You may be able to join if your diagnosis is mild and you can complete repeated sleep and thinking questionnaires with a family caregiver’s help.
Montpellier, HéraultAges 50–85 - NCT06614504RecruitingPhase 2
Nicotine control for dual e-cigarette and cigarette users
This study is testing how to help people who both smoke cigarettes and use e-cigarettes. It looks at ways to control nicotine use to help you quit or cut back.
Providence, Rhode IslandAges 21 years+ - NCT06899594RecruitingEarly Phase 1
Psilocybin for quitting methamphetamine
This trial tests whether psilocybin (a psychedelic medicine) can help people quit methamphetamine. You'll receive counseling before, during, and after the drug session, and your progress will be followed for several months.
Shreveport, LouisianaAges 25–65 - NCT06895863Recruiting
Personalized magnetic brain therapy for hard to treat depression
This study tests a new way to use magnetic brain stimulation tailored to each patient to treat depression that hasn't improved with at least two different medications. It may help people who are still struggling with moderate to severe depression.
Glostrup MunicipalityAges 18–95 - NCT06892847Recruiting
Brain stimulation for anxiety and depression in youth
This study tests if a non-invasive brain stimulation technique called TMS can help reduce symptoms of anxiety or depression in children and teens. It involves sessions where a magnetic field is used to gently stimulate parts of the brain, and is designed for young people aged 6 to 18 who have been diagnosed with these conditions.
Calgary, AlbertaAges 6–18 - NCT06898606RecruitingPhase 1/Phase 2
Psilocybin mushrooms with or without Prozac for stubborn depression
This study tests whether a dose of psilocybin (the active ingredient in magic mushrooms) can help treat depression that hasn't improved with standard antidepressants. Some participants will also take the antidepressant fluoxetine (Prozac) to see if it changes the effects.
Foz do Iguaçu, ParanáAges 25–65 - NCT06897670Recruiting
Brain blood flow patterns in mood and memory disorders
This study uses a headband with light sensors (fNIRS) to measure blood flow in the brain while you do thinking tasks. It aims to understand differences in brain activity for people with depression, bipolar disorder, or mild memory loss.
Rochester, MinnesotaAges 18 years+ - NCT06898593Recruiting
Including patient goals in collaborative care
This trial looks at ways to better include your personal goals and concerns in your care if you're already in the Collaborative Care Model at Dartmouth Health. It aims to make your treatment more focused on what matters to you.
Concord, New HampshireAges 18–100 - NCT06891300RecruitingPhase 2/Phase 3
Ketamine for Suicidal Thoughts in Depression
This study tests if ketamine can help reduce suicidal thoughts in people with major depression. You'll receive ketamine treatment and be monitored closely.
Ottawa, OntarioAges 18–65 - NCT06900712Recruiting
Single-session program for sexual assault recovery
This trial tests a one-time session designed to help survivors of unwanted sexual contact or assault reduce symptoms of PTSD or depression. It may be a good fit if you live in Ohio and have had these symptoms for at least a month.
Cleveland, OhioAges 18–65 - NCT06898788RecruitingEarly Phase 1
Probiotics for depression in teens and young adults
This study tests whether a probiotic supplement can help improve depression in young people who are already taking an SSRI antidepressant. If you join, you will take a probiotic or placebo for several weeks and have your mood and brain activity checked.
San Francisco, CaliforniaAges 15–24 - NCT06898476Recruiting
Silkworm pupa powder for Alzheimer's disease
This study tests if a powder made from silkworm pupae can help improve memory and thinking in people with Alzheimer's disease. It is for people with mild to severe Alzheimer's who have clear signs of the disease in their blood or brain scans.
Hangzhou, ZhejiangAges 50–90 - NCT06891690Recruiting
Brain stimulation for neurological and gynecological conditions
This trial tests whether a gentle brain stimulation technique called tDCS can help people with neurological problems (like weakness in arms or legs) or certain gynecological conditions (like endometriosis or painful periods) who are not using other treatments. It aims to see if tDCS can improve symptoms.
PoznanAges 18–90 - NCT06898177Recruiting
Mobile app for ARFID therapy
This study tests a mobile app that provides cognitive-behavioral therapy for avoidant/restrictive food intake disorder (ARFID). It aims to help people who have trouble eating enough or a limited variety of foods, and can be done from home using a smartphone.
Boston, MassachusettsAges 18–55 - NCT06898099Recruiting
Hypnotherapy for chronic insomnia in primary care
This study tests whether 4 short hypnotherapy sessions can help people with chronic insomnia. It is designed for adults who struggle with sleep for months and want a non-drug option in their regular doctor's office.
Bain-de-BretagneAges 18 years+ - NCT06900673Enrolling by invitationEarly Phase 1
ADHD support program for families and schools
This study tests a technology-based program to help teachers and parents better support children with ADHD. It aims to make proven treatments more accessible for families in need.
San Diego, CaliforniaAges 7 years+ - NCT06899165RecruitingPhase 2
Psilocybin therapy for inherited trauma
This trial tests whether psilocybin (a psychedelic substance) combined with therapy can help adult children of genocide survivors who experience symptoms of trauma, depression, or anxiety. The goal is to see if this approach can reduce the emotional impact of intergenerational trauma.
New York, New YorkAges 18 years+ - NCT06897007Recruiting
Ciprofol dosage in patients with insomnia under anesthesia
This study looks at how the sedative drug ciprofol works differently in people with insomnia compared to those who sleep well. It aims to help doctors give the right dose for your type of surgery.
Beijing, Beijing MunicipalityAges 18–64 - NCT06896279Recruiting
Temporal interference brain stimulation for consciousness disorders
This trial tests a new type of brain stimulation called temporal interference (TI) to see if it can help people with severe disorders of consciousness. If you or your loved one has been in a minimally conscious or vegetative state for at least a month and is medically stable, this study may be an option.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05549102Recruiting
CBT therapy study for anxiety and brain circuit changes
This trial studies whether a specific form of talk therapy (CBT) changes brain activity in people with moderate anxiety. It may help your care team understand what works best and how brain “circuits” respond to treatment.
LondonAges 18–64 - NCT06800989Recruiting
Can sophrology with a wearable device reduce chemo anxiety?
This study tests whether a relaxation technique called sophrology, guided by a wearable device, can help reduce anxiety during chemotherapy for early-stage breast cancer. It aims to offer extra support during treatment.
AngersAges 18 years+ - NCT06881277Recruiting
Smartphone app for healthy eating and activity after pregnancy
This trial tests a smartphone app called PRIMI to help new mothers who have moved to Sweden eat well and stay active. If you are a first-generation migrant woman who gave birth within the last 6 months, you may be able to join.
Linköping, Östergötland CountyAges 18 years+
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,780 recruiting psychiatry studies from the U.S. registry right now, out of 12,430 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.