Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,780 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1251
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease339
- Autism Spectrum Disorder240
- Dementia227
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder142
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Suicidal Ideation89
- Mild Cognitive Impairment (MCI)88
Leading sponsors
- VA Office of Research and Development105
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- The University of Hong Kong51
- Karolinska Institutet50
Where studies are running
- California520
- Massachusetts267
- New York256
- Texas209
- Maryland176
- Pennsylvania171
- Florida149
- Alabama118
- Arizona108
- Illinois104
Recruiting studies7,780 total
- NCT06866275RecruitingPhase 2
Suramin for autism in boys aged 5–14
This trial tests if a medicine called suramin (KZ101) can help with social challenges in boys with autism. It's a 12-week study at one location, and families must be able to visit the site easily.
Orange, CaliforniaAges 5–14 - NCT06860724Recruiting
Stress and blood vessel health study for adults 18-55
This study looks at how daily stress affects blood vessel function in healthy adults and those with depression. It aims to find links between emotions and physical health.
Newark, DelawareAges 18–55 - NCT06862960RecruitingPhase 2
Ozanimod for moderate Alzheimer's disease
This trial tests whether a daily pill called ozanimod can help people with moderate Alzheimer's disease. The study monitors changes in thinking and memory over time and requires a study partner who can join visits.
Fuzhou, FujianAges 55–80 - NCT06163651Recruiting
Parent-child support program for parents of young children
This trial tests a one-year program to help parents with young children. It offers support and resources to strengthen your family.
Enid, OklahomaAges 18 years+ - NCT06213324RecruitingPhase 4
Ketamine's effects on brain circuits in depression
This trial studies how ketamine affects brain circuits in people with depression compared to healthy volunteers. It involves a single infusion of ketamine and brain scans before and after.
New York, New YorkAges 18–65 - NCT04199299Recruiting
Communication sensors for people who can’t express needs clearly
This trial tests a wearable sensor system that may help people who have difficulty communicating their needs clearly. It may capture signals from the body so caregivers and devices can better understand reactions and needs.
OsloAges 5–80 - NCT04938362Recruiting
Study brain recovery after abscess using memory and brain scans
This study looks at how thinking and energy levels change after a brain abscess. It may help researchers understand what affects recovery and fatigue, using thinking tests and brain imaging/brain-wave checks.
OsloAges 16 years+ - NCT05141591Recruiting
Anxiety before ENT surgery and opioid use after surgery
This trial looks at whether people’s anxiety before ear, nose, and throat (ENT) surgery affects how much pain medicine (opioids) they need after surgery. It may help doctors better plan pain control based on anxiety level and possibly gender-related patterns.
Vienna, State of ViennaAges 18 years+ - NCT05738278Recruiting
Care changes guided by heart rate in non-speaking autistic people
This study tests whether using a person’s heart rate to guide care can improve day-to-day support for autistic people who do not communicate verbally. It’s aimed at people who live in a care home or attend a staffed day program most days of the week.
OsloAges 5–70 - NCT05059158Recruiting
Study how the brain clears amyloid in Alzheimer’s
This trial studies how the brain removes amyloid-β, a protein linked to Alzheimer’s disease. It may help researchers understand what’s happening in people with mild memory impairment or Alzheimer’s, and guide better treatments in the future.
München, BavariaAges 50–85 - NCT06852469RecruitingPhase 4
GABA test for PTSD in veterans
This trial uses a medication called lorazepam to study how GABA receptors work in veterans with PTSD. It aims to learn more about brain chemistry related to PTSD and how it might affect treatment.
San Diego, CaliforniaAges 18–65 - NCT06847321RecruitingPhase 2
Testing LHP588 for Alzheimer's linked to a mouth bacteria
This trial tests a new medication, LHP588, for people with Alzheimer's who also have a common mouth bacteria called P. gingivalis. The goal is to see if targeting this bacteria can help slow down memory loss.
Phoenix, ArizonaAges 55–80 - NCT06854328Recruiting
Prism PTSD study for adolescents
This trial tests a new non-invasive device that uses brain imaging to help treat PTSD symptoms in teens and young adults. It may be a good option if you haven't yet completed a full course of trauma-focused therapy.
New York, New YorkAges 12–21 - NCT06854731Recruiting
Preventing falls in older adults with cognitive frailty
This trial studies a program to help older adults with mild memory problems and physical frailty reduce their risk of falling. It tests a home-based exercise and fall-prevention plan to improve strength and balance.
Vancouver, British ColumbiaAges 65–89 - NCT06849869Recruiting
Collaborative care for perinatal wellness
This trial tests a collaborative care model to support the mental health and wellness of pregnant and postpartum people. It aims to improve access to care and outcomes for all patients at participating clinics.
Providence, Rhode IslandAges 18 years+ - NCT06849583Enrolling by invitation
Testing how pre-surgery checkups affect anxiety and satisfaction
This study looks at how talking to an anesthesiologist before surgery affects your worry and how happy you are with your care. It compares different ways of checking anxiety to find which one works best.
IstanbulAges 16–85 - NCT06854224RecruitingPhase 2
Testing a sleep drug for suicide risk in veterans with depression
This trial tests whether a medication called suvorexant (used for sleep) can help lower suicide risk in veterans who have major depression and have attempted suicide before. The study aims to see if blocking a brain chemical called orexin reduces suicidal thoughts.
The Bronx, New YorkAges 18–70 - NCT06851273Recruiting
Guided self-help for families of teens with anorexia
This study tests a guided self-help program for families of teens with anorexia nervosa. It is designed to be completed online from home, with support from a trained therapist.
Hamilton, OntarioAges 12–100 - NCT06852027Enrolling by invitation
Dietary practices for children with autism aged 3-10
This trial tests two special diets (gluten-free casein-free and Feingold) for children with autism who have tummy troubles or other symptoms. It aims to see if changing what they eat can help.
AydinAges 3–10 - NCT06853665RecruitingPhase 4
Study of mixed amphetamine for autism and ADHD in teens
This trial tests if a mixed amphetamine medication helps teenagers with both autism and ADHD who still have significant symptoms, even if they are already on other treatments. It also includes typically developing teens as a comparison group.
Boston, MassachusettsAges 8–18 - NCT06847763Recruiting
Online pain education for chronic low back pain
This study tests an online class that teaches you about how your brain and nerves process pain, to help you manage chronic low back pain. It is a long-term program you can join from home.
Istanbul, AtasehirAges 20–60 - NCT06847399RecruitingPhase 2
Tirzepatide for Binge Eating Disorder
This trial tests if tirzepatide (a weekly injection) can help reduce binge eating compared to a placebo or another medication (lisdexamfetamine dimesylate). It may be a good fit for people with moderate or severe binge eating disorder who also have a high body weight.
Baltimore, MarylandAges 18 years+ - NCT06853587Recruiting
Genetic test to help pick antidepressant for teens
This study tests whether using a cheek swab DNA test can help choose a better antidepressant for teenagers with anxiety or depression. The goal is to see if this personalized approach leads to fewer side effects and better results.
Calgary, AlbertaAges 12–17 - NCT06857539Recruiting
Assessing thinking and movement in high-risk infants
This study looks at how high-risk infants (especially those born early or with brain concerns) develop their thinking and movement skills over time, comparing them to healthy babies. The goal is to better understand and support their development.
CorkAges birth–4 months
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,780 recruiting psychiatry studies from the U.S. registry right now, out of 12,430 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.