Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,780 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1251
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease339
- Autism Spectrum Disorder240
- Dementia227
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder142
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Suicidal Ideation89
- Mild Cognitive Impairment (MCI)88
Leading sponsors
- VA Office of Research and Development105
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- The University of Hong Kong51
- Karolinska Institutet50
Where studies are running
- California520
- Massachusetts267
- New York256
- Texas209
- Maryland176
- Pennsylvania171
- Florida149
- Alabama118
- Arizona108
- Illinois104
Recruiting studies7,780 total
- NCT06743282Enrolling by invitation
Study on mobile support for substance use in primary care
This trial tests a program called Senyo Health that provides support through text messages and video calls for people with substance use concerns. It aims to help you manage your substance use while working with your primary care doctor.
Scottsdale, ArizonaAges 18 years+ - NCT06749392Recruiting
Depression treatment based on your brain's activity
This study tests a personalized treatment for depression that uses your brain's electrical activity (EEG) to guide therapy. You attend sessions where we monitor your brain's response to help improve your mood.
HaifaAges 18–65 - NCT06740747Recruiting
Brain stimulation for schizophrenia symptoms
This study tests a new type of brain stimulation (called intermittent theta-burst stimulation) to see if it helps with symptoms like lack of motivation or trouble thinking clearly in people with schizophrenia. You will also have an MRI scan to see how the brain changes.
Hanover, Lower SaxonyAges 18–65 - NCT06746987Enrolling by invitation
Meditation for sleep and mood in older adults
This trial studies whether a meditation program can help people aged 65 and older sleep better and feel emotionally healthier. You'll be asked to practice meditation and report changes in your sleep and mood.
MersinAges 65–95 - NCT06747689Recruiting
Sleep quality and self-care in heart failure
This study looks at how sleep quality affects the ability of people with heart failure to manage their own health. It aims to find if better sleep leads to better self-care.
IzmirAges 18 years+ - NCT06749444Recruiting
Cognitive behavioral therapy for sleep issues in schizophrenia
This trial tests if a talking therapy focused on sleep and daily rhythms (CBT-I) can help people with schizophrenia who have not responded well to other treatments and have trouble sleeping. It aims to improve sleep quality without medication.
Glostrup, DenmarkAges 18–64 - NCT06740331Recruiting
Thinking and memory study for mood disorders
This study looks at how people with bipolar disorder or depression process social situations, memory, and thinking. It compares patients, their relatives, and healthy volunteers to better understand these conditions.
ReimsAges 18–65 - NCT06741553Recruiting
Studying lecanemab for early Alzheimer's disease
This study looks at how well lecanemab works for people with early Alzheimer's disease. It aims to see if the drug can help slow down memory and thinking problems.
Hangzhou, ZhejiangAges Up to 85 years - NCT06740890RecruitingPhase 4
Exercise and a new medication for schizophrenia or bipolar disorder
This study tests whether a combination of a daily medication (olanzapine-samidorphan) and a structured exercise program can help people with schizophrenia, schizoaffective disorder, or bipolar disorder improve their health and well-being.
New York, New YorkAges 18–65 - NCT06747442Recruiting
Native moms' recovery program during pregnancy
This study offers support for Native American and Alaska Native pregnant women who want recovery from substance use. The program connects you with your culture and community to help you and your baby.
Salt Lake City, UtahAges 18 years+ - NCT06746155Recruiting
Predictors of relapse in major depression
This study looks at adults with major depressive disorder who have responded to treatment, to find out what might predict a relapse. You will wear a wrist activity monitor and complete questionnaires.
Calgary, AlbertaAges 18–70 - NCT06745011Enrolling by invitation
Parkinson's signs in people with nerve damage
This study looks for early signs of Parkinson's disease in people who have nerve damage in their hands and feet (polyneuropathy) with no known cause, along with drops in blood pressure when standing up. It aims to understand if these early symptoms might predict future Parkinson's.
Aarhus, JutlandAges 18–85 - NCT06748209RecruitingPhase 4
Mobile TMS for treatment-resistant depression
This trial tests if delivering transcranial magnetic stimulation (TMS) through a mobile unit can help people with depression that hasn't improved with other treatments.
Charleston, South CarolinaAges 22–80 - NCT06749197Recruiting
Home-based cognitive rehab for brain injury
This study tests a home-based computerized brain training program for people with acquired brain injury. It aims to help improve thinking skills like memory and attention through exercises you can do on your own computer or tablet.
Rotterdam, South HollandAges 18 years+ - NCT06741865Recruiting
Helping older adults keep their minds sharp (INSPIRE-Faith)
This trial tests whether certain lifestyle and thinking exercises help preserve memory and brain function in older adults, especially in the African American community. You may join if you are 55 or older and your memory is normal or mildly impaired.
Los Angeles, CaliforniaAges 55–85 - NCT06740487Recruiting
AR therapy for PTSD in military members
This study tests a new therapy using augmented reality (a type of headset that adds digital images to what you see) to help treat posttraumatic stress disorder (PTSD) in current or former military members. The therapy aims to make exposure therapy more effective by letting you face trauma-related situations in a controlled, virtual way.
Charleston, South CarolinaAges 18 years+ - NCT06743373Recruiting
Cannabis and sleep in young adults
This study looks at how cannabis affects sleep, daily rhythms, and sensitivity to light in young adults. You would either stop using cannabis for 4 weeks (if you are a regular user) or serve as a non-user control, to compare sleep patterns.
Pittsburgh, PennsylvaniaAges 18–25 - NCT06743711Recruiting
Heart fitness in severe mental illness study
This study checks how fit your heart and lungs are if you have a serious mental illness like schizophrenia or bipolar disorder. It aims to see if fitness can help improve health and well-being.
Glostrup MunicipalityAges 18–45 - NCT06745349Recruiting
Online sleep course for adults in Saskatchewan
This study tests an online sleep course for adults who have trouble falling or staying asleep. It aims to help improve sleep without requiring in-person visits.
Regina, SaskatchewanAges 18 years+ - NCT06745765Recruiting
Virtual reality for anxiety during CT-guided biopsy
This study tests whether using a virtual reality (VR) headset during a CT-guided biopsy can help lower anxiety. If you are having this procedure while awake, you may be able to use VR to feel more comfortable.
Bologna, BolognaAges 18 years+ - NCT06745479Recruiting
Understanding decision-making in schizophrenia with brain scans
This study uses brain scans and real-life surveys to understand how people with or without schizophrenia make decisions. It may help researchers learn how the brain works differently in schizophrenia.
Piscataway, New JerseyAges 18–50 - NCT06740383Recruiting
Study of early psychosis and treatments
This study looks at people who have had psychosis for less than 4 years to understand how their symptoms change over time and how they respond to treatment. By using brain scans and other tests, researchers hope to find better ways to personalize care for early psychosis.
Hartford, ConnecticutAges 18–40 - NCT06746818Enrolling by invitation
Building resilience in older adults with PTSD
This trial tests if a HeartMath-based program can help older adults improve resilience, reduce posttraumatic stress, and boost spiritual and psychosocial well-being. It may be an option if you are 60 or older and have experienced trauma.
Al MansurahAges 60 years+ - NCT06739967Recruiting
Speech Therapy for Italian Speakers with PPA
This study tests speech and language therapy for people with primary progressive aphasia (PPA). It aims to see if targeted exercises can help maintain or improve communication skills.
BariAges 40–85
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,780 recruiting psychiatry studies from the U.S. registry right now, out of 12,430 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.