Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,780 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1251
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease339
- Autism Spectrum Disorder240
- Dementia227
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder142
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Suicidal Ideation89
- Mild Cognitive Impairment (MCI)88
Leading sponsors
- VA Office of Research and Development105
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- The University of Hong Kong51
- Karolinska Institutet50
Where studies are running
- California520
- Massachusetts267
- New York256
- Texas209
- Maryland176
- Pennsylvania171
- Florida149
- Alabama118
- Arizona108
- Illinois104
Recruiting studies7,780 total
- NCT06745765Recruiting
Virtual reality for anxiety during CT-guided biopsy
This study tests whether using a virtual reality (VR) headset during a CT-guided biopsy can help lower anxiety. If you are having this procedure while awake, you may be able to use VR to feel more comfortable.
Bologna, BolognaAges 18 years+ - NCT05957848RecruitingPhase 2
Guanfacine for teens with cannabis use problems
This Phase 2 study tests whether extended-release guanfacine can reduce cannabis use in adolescents and young adults. It may help by targeting brain pathways that can drive cravings or continued use.
Parkville, VictoriaAges 12–25 - NCT06492109Recruiting
Blood study on sleep loss
This study looks at blood samples to understand how sleep loss affects the body. It may help find new ways to diagnose or treat sleep problems.
Hangzhou, ZhejiangAges 18–80 - NCT06496139Recruiting
Online therapy for emotional symptoms before your period
This study tests an online therapy program to help with intense emotional symptoms before your period. It may be a good fit if you have been diagnosed with PMDD and speak Swedish.
Uppsala, Uppsala CountyAges 18–45 - NCT06557642Recruiting
Laughing Gas and Emotional Thinking Study
This study tests how nitrous oxide (laughing gas) affects your emotions and thinking. It's looking for healthy volunteers ages 18 to 40 to see how the gas might change emotional processing.
OxfordAges 18–40 - NCT06266611RecruitingPhase 2
Cannabis for cancer symptom relief
This trial tests whether cannabis can help cancer patients manage symptoms like sleep trouble, pain, and mood changes. It's for people who are new to using cannabis for these issues.
Aurora, ColoradoAges 25 years+ - NCT06717165Recruiting
Brain stimulation with talk therapy for OCD
This study tests if adding a gentle brain stimulation technique (tACS) to cognitive behavioral therapy (CBT) can help reduce OCD symptoms more than CBT alone. It is for adults with OCD who have not completed a full course of CBT before.
Shanghai, Shanghai MunicipalityAges 18–60 - NCT06727773RecruitingPhase 2
Memantine and exercise to protect thinking during chemo for breast cancer
This study tests whether a medicine called memantine combined with a structured exercise program can help protect your thinking and memory during chemotherapy for breast cancer. It may also help understand how these treatments work in the body.
Chapel Hill, North CarolinaAges 18 years+ - NCT06727461Enrolling by invitation
Home feeding program for advanced dementia
This study tests a home feeding program called FEED@Home for people with advanced dementia who have trouble eating. It helps families keep their loved one eating by mouth safely at home, avoiding a feeding tube.
Hong KongAges 60 years+ - NCT06736483RecruitingPhase 2
Dexmedetomidine for children’s groin surgery recovery
This trial tests whether adding a sedative called dexmedetomidine to a numbing shot (nerve block) helps children aged 1–7 recover better after groin surgery. The goal is to improve comfort and reduce side effects.
Montpellier, FranceAges 1–7 - NCT06737627Recruiting
Eye health testing for adults with intellectual disability
This study develops an eye exam battery for adults with intellectual disability (ID). Researchers want to see if caregivers can help identify common eye problems in this group.
New Taipei CityAges 20 years+ - NCT06736548Enrolling by invitation
Sleep treatment program for cancer survivors
This study tests a sleep education program for cancer survivors who have trouble sleeping. You will learn strategies to improve your sleep and overall well-being.
Boston, MassachusettsAges 18–89 - NCT06731049Recruiting
Walking training with and without dual tasks for Alzheimer's
This study compares treadmill walking to walking while doing a second task (like talking or carrying something) in people with Alzheimer's disease. It aims to see which training method improves mobility and safety better.
IstanbulAges 65–85 - NCT06736522Recruiting
Youth leadership and mindfulness program for high school students
This study tests a program designed to build leadership skills, engagement, and mindfulness in high school students. If you're a teen in certain Massachusetts or Illinois schools, this program may help you grow personally and socially.
Chicago, IllinoisAges 14 years+ - NCT06735885Recruiting
Brain training with feedback app for depression
This trial tests whether a smartphone app combined with brain scanning (fMRI) can help people with depression. You will get real-time feedback on your brain activity to learn how to improve your mood.
Stanford, CaliforniaAges 18–80 - NCT06732596Recruiting
Recovery support app for people on buprenorphine
This study tests a smartphone app that uses a conversational helper to support people in recovery from opioid use disorder who are taking buprenorphine. It aims to help you stay on track with treatment.
Boston, MassachusettsAges 18 years+ - NCT06736444Recruiting
Sleep and Substance Use Help for Young Adults
This study tests a brief program to help young adults who struggle with sleep and also use alcohol or cannabis. The program teaches skills to improve sleep quality and reduce risky substance use.
Seattle, WashingtonAges 18–29 - NCT06729294Recruiting
Does music help during knee replacement surgery?
This study tests if listening to music during knee replacement surgery under spinal anesthesia can lower anxiety, pain, and stress hormone levels. It may help make the experience calmer for patients.
Kocasinan, KayseriAges 18 years+ - NCT06733376Recruiting
PTSD treatment options study
This study tests different types of talk therapy for PTSD, like CPT, PE, and STAIR. It aims to find which treatment works best for people with PTSD.
Chicago, IllinoisAges 18 years+ - NCT06734767Enrolling by invitation
Mindfulness course for stress and burnout in doctors
This trial is testing a mindfulness-based stress reduction (MBSR) course to see if it helps doctors and medical faculty feel less stressed and burned out. It is open to any physician at Mount Sinai.
New York, New YorkAges Any age - NCT06736769Enrolling by invitationPhase 2
Ketamine and learning in eating disorders
This study tests whether a single dose of ketamine can help people with anorexia nervosa learn new ways of thinking about food and body image during recovery. You may be eligible if you are a teenager or young adult currently hospitalized for malnutrition.
San Francisco, CaliforniaAges 16–26 - NCT06732284Recruiting
Sleep inertia study in depression
This study looks at sleep inertia (the grogginess you feel after waking up) in people with major depression. It uses a simple reaction-time test to understand how depression affects waking up.
NîmesAges 18–54 - NCT06734546Recruiting
Exercise and brain health in type 2 diabetes
This study tests whether regular exercise can improve brain health in people with type 2 diabetes. If you have type 2 diabetes, are not on insulin, are inactive, and are between 30 and 75 years old, you may be able to join.
Hasselt, LimburgAges 30–75 - NCT06735950Recruiting
Volunteering in place for assisted living residents with dementia
This study tests a program where assisted living residents with memory problems and apathy (feeling unmotivated) take part in volunteer activities in their community. The goal is to see if volunteering can improve mood, engagement, and quality of life.
Catonsville, MarylandAges 55 years+
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,780 recruiting psychiatry studies from the U.S. registry right now, out of 12,430 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.