Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,780 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1251
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease339
- Autism Spectrum Disorder240
- Dementia227
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder142
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Suicidal Ideation89
- Mild Cognitive Impairment (MCI)88
Leading sponsors
- VA Office of Research and Development105
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- The University of Hong Kong51
- Karolinska Institutet50
Where studies are running
- California520
- Massachusetts267
- New York256
- Texas209
- Maryland176
- Pennsylvania171
- Florida149
- Alabama118
- Arizona108
- Illinois104
Recruiting studies7,780 total
- NCT06650527Recruiting
Empathy training for dementia caregivers
This study tests a cognitive empathy training program for people caring for a family member with dementia. The training is designed to help caregivers better understand their loved one's perspective and reduce stress. You may benefit if you live with the person you care for and feel burdened by your caregiving role.
Atlanta, GeorgiaAges 50 years+ - NCT06651684Recruiting
Quit smoking help for parents with social needs
This trial tests if health navigators can help parents who smoke and have unmet social needs to quit smoking. If you smoke and face challenges like trouble paying bills or finding childcare, this program may support you.
Montreal, QuebecAges 18 years+ - NCT06656533Recruiting
Timing of brain stimulation to improve insomnia treatment
This study tests whether giving a specific type of brain stimulation (rTMS) at the right time can help make insomnia treatment work better. It may be an option for people ages 25 to 45 who have trouble sleeping and live near Stanford University.
Palo Alto, CaliforniaAges 25–45 - NCT06648928Enrolling by invitation
App for reducing PTSD in Florida 9/11 responders
This study is testing a mobile app called PTSD Coach, along with support from a clinician, to help World Trade Center responders in Florida reduce symptoms of post-traumatic stress. It may be a good fit if you have some PTSD symptoms but not severe alcohol or drug use, and you are not already receiving PTSD treatment.
Miami, FloridaAges Any age - NCT06647589Recruiting
Acceptance and commitment therapy for religious ocd
This study tests a therapy called acceptance and commitment therapy (ACT) to help people with religious obsessions and compulsions (scrupulosity). It aims to reduce distress and improve daily functioning.
Birmingham, AlabamaAges 18 years+ - NCT06651177RecruitingPhase 2
Tirzepatide with buprenorphine for opioid use disorder
This study tests whether adding tirzepatide, a medication used for weight and blood sugar, to buprenorphine treatment helps people with opioid use disorder. It aims to see if the combination improves outcomes compared to buprenorphine alone.
Jacksonville, FloridaAges 18 years+ - NCT06649929Enrolling by invitationPhase 2
Better sleep for Latino couples and brain health
This study tests a program to help Latino couples improve sleep and CPAP use, which may lower Alzheimer's risk. You and your partner will join telehealth sessions together.
Tuscon, ArizonaAges 35 years+ - NCT06650267RecruitingPhase 2
Substance use and family violence treatment for fathers
This study tests a treatment program for fathers who have both a substance use disorder and a history of family violence within the last 18 months. The goal is to see if the program helps reduce substance misuse and improve family relationships.
New Haven, ConnecticutAges 18 years+ - NCT06647498RecruitingPhase 2/Phase 3
Study of a treatment for early-onset Alzheimer's caused by a gene change
This study tests a potential disease-modifying treatment for people who have a specific gene mutation that causes early-onset Alzheimer's disease. The goal is to see if the treatment can delay or prevent symptoms.
Birmingham, AlabamaAges 18 years+ - NCT06651554Recruiting
Suicide prevention app study for teens in Bogota
This trial tests a digital platform designed to help prevent suicide among teenagers. It aims to make mental health support more accessible for students in Bogota schools.
Bogotá, ColombiaAges 14–19 - NCT06651528Enrolling by invitation
Trauma support program for substance use and reentry
This study tests a program for people in correctional facilities who have experienced violence and are in substance use treatment. It helps you prepare for release by building a support system in the community.
Frankfort, KentuckyAges 18–99 - NCT04746261Recruiting
Suicide care support program after a recent attempt
This study tests a brief, structured support program (ASSIP) for adults who have recently had a suicide attempt. It may help people cope better and stay connected to care after discharge from psychiatric or primary care.
LundAges 18 years+ - NCT06088953Recruiting
Early hearing check for memory clinic patients
This study looks at how to detect hearing loss early in people with mild to moderate memory problems. It may help understand if hearing issues affect thinking skills.
LilleAges 50 years+ - NCT06633016RecruitingPhase 2
ABX-002 for major depression (add-on treatment)
This trial tests a new medication called ABX-002 as an add-on to your current antidepressant. It's for people with moderate to severe depression who haven't gotten enough help from their current antidepressant alone.
Birmingham, AlabamaAges 18–65 - NCT06641726Recruiting
Global database linking genetics and health records for mental illness
This trial is building a research database that combines genetic information and long-term health data to improve personalized treatment for serious mental illness. You may be eligible if you have been diagnosed or treated for depression, bipolar disorder, schizophrenia, or dementia.
Oxford, OxfordAges 18–110 - NCT06641297Recruiting
Brain Wiring Study in Schizophrenia
This study uses MRI scans to look at brain changes in people with schizophrenia. It aims to understand how the brain's wiring (called white matter) changes over time.
Catonsville, MarylandAges 15–45 - NCT06639438Recruiting
Sensory outcomes in people who use opioids
This study looks at how opioids affect the senses in people having planned surgery. Researchers want to compare patients who use opioids (for pain or addiction) with those who don't, to see if there are differences in sensation.
Boston, MassachusettsAges 18 years+ - NCT06639477Recruiting
Mood and sleep improvement study for older adults
This study tests whether adding a sleep treatment to regular depression medication can improve both mood and sleep in adults aged 55 and older. It may help if you have ongoing depression, sleep problems, and are already taking antidepressant medication.
Los Angeles, CaliforniaAges 55 years+ - NCT06636318Recruiting
Immune changes during 24-hour surgery call
This study looks at how being on call for 24 hours affects the immune system of surgery residents. The goal is to see if these long shifts change how the body fights infection.
Chicago, IllinoisAges 18 years+ - NCT06635486Recruiting
Mental health support for Venezuelans in Lima
This study offers mental health support to Venezuelan adults living in Lima who are feeling anxious, depressed, or have experienced trauma. It will check if you have signs of depression, anxiety, or post-traumatic stress and provide help if you do.
LimaAges 18 years+ - NCT06633900RecruitingPhase 2/Phase 3
Testing naltrexone to prevent overdose in stimulant users
This trial tests whether naltrexone, a medication that blocks the effects of opioids, can help prevent overdose in people who use stimulants like cocaine or methamphetamine. It may be a good fit if you are at risk for HIV or living with HIV, and have a stimulant use disorder or use stimulants at least 10 days per month.
San Francisco, CaliforniaAges 18 years+ - NCT06633263Enrolling by invitation
Combined therapy for depression and insomnia
This trial tests a combination of two behavioral therapies to improve both depression symptoms and sleep problems. It may help you if you have moderate depression and insomnia and can participate in French-language sessions.
LiègeAges 18–67 - NCT06640803Recruiting
Early psychosis risk stepped-care program
This study offers a step-by-step care program for teens and young adults at high risk for psychosis. It aims to provide the right level of support early on to prevent or reduce the severity of symptoms.
Elk Grove, CaliforniaAges 12–25 - NCT06639464RecruitingPhase 2
Semaglutide for improving opioid recovery outcomes
This study tests whether semaglutide (a medication used for weight management) can help people on buprenorphine or methadone reduce their opioid use. If it works, it could provide additional support during recovery.
Boston, MassachusettsAges 18 years+
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,780 recruiting psychiatry studies from the U.S. registry right now, out of 12,430 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.