Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,780 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1251
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease339
- Autism Spectrum Disorder240
- Dementia227
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder142
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Suicidal Ideation89
- Mild Cognitive Impairment (MCI)88
Leading sponsors
- VA Office of Research and Development105
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- The University of Hong Kong51
- Karolinska Institutet50
Where studies are running
- California520
- Massachusetts267
- New York256
- Texas209
- Maryland176
- Pennsylvania171
- Florida149
- Alabama118
- Arizona108
- Illinois104
Recruiting studies7,780 total
- NCT06626789RecruitingPhase 1/Phase 2
Brain signal training to help regulate emotions
This study tests a new brain-training technique that may help people with borderline personality disorder manage their emotions better. You will do mental exercises while an MRI scans your brain, and the results will show whether this training can reduce emotional distress.
Freiburg im BreisgauAges 18–65 - NCT06618872Recruiting
Comparing tau and amyloid PET scans for memory problems
This study compares two types of brain PET scans (tau and amyloid) to see which one better helps diagnose memory problems. You may be eligible if you have mild cognitive impairment or mild dementia and your doctor has already ordered an amyloid PET scan.
Geneva, Canton of GenevaAges 50–85 - NCT06619964Enrolling by invitation
Study on nicotine levels in e-liquids
This trial tests how different nicotine levels in e-liquids affect people who use pod or pen-style vapes daily. It aims to help regulators make better rules about nicotine content.
Rochester, New YorkAges 21 years+ - NCT05840900Recruiting
Mindfulness and optimism program for first-time pregnancy wellbeing
This study tests a mindfulness- and optimism-focused program to support wellbeing and resilience during pregnancy. It may help people, especially those who naturally feel less optimistic, learn stress-support skills during early pregnancy.
Providence, Rhode IslandAges 18 years+ - NCT06606002Recruiting
Group therapy for borderline symptoms in teens
This study tests if group schema therapy helps teenagers reduce borderline personality symptoms. It may be a good option if you have some borderline traits and can attend group sessions in Finnish.
Turku, Southwest FinlandAges 15–22 - NCT06601140Recruiting
Testing a smartphone app for tracking depression symptoms
This study tests a smartphone-based emotional monitoring device (EMOCARE) to see if it can accurately measure your mood compared to a standard depression questionnaire. It may help researchers find a simpler way to track depression symptoms.
AgenAges 18 years+ - NCT06605105Enrolling by invitationPhase 3
Long-term extension trial of CYB003 for depression
This long-term study is for people who already completed an earlier trial of the experimental drug CYB003 for major depression and who stayed on their regular antidepressant. It looks at the safety and effects of taking CYB003 again over many months.
Phoenix, ArizonaAges 18–85 - NCT05427708Recruiting
Breathing training to reduce anxiety symptoms
This study tests whether specific respiratory (breathing) training can reduce anxiety symptoms and fear responses. It may help people who have several kinds of anxiety or trauma-related anxiety, especially if they are not on anxiety medicines or only stable on them.
Austin, TexasAges 18 years+ - NCT05331534Recruiting
Attentional therapy for PTSD symptoms after trauma
This trial studies whether a therapy focused on attention can reduce post-traumatic stress disorder (PTSD) symptoms. You may qualify if you have PTSD diagnosed by standard questionnaires and interviews, and if you can safely take part in the therapy sessions.
LilleAges 18–60 - NCT05540548Recruiting
Podiatry assessment for balance and pain in chronic back pain
This study looks at whether a foot and posture specialist can help measure how balance relates to the pain you feel in chronic low back pain. It may help doctors better understand what to focus on for pain that lasts for months.
ValenciennesAges 18 years+ - NCT05800899Recruiting
Brief counseling program for alcohol-related injuries in Latinxs
This trial tests a culturally tailored, short counseling session for people who are Latinx and have alcohol-related injuries. It aims to reduce health disparities by helping improve treatment access and outcomes after an injury.
El Paso, TexasAges 18 years+ - NCT06613334Recruiting
Voice recordings to predict schizophrenia relapse
This study tests whether voice recordings can help predict when someone with schizophrenia might have a relapse. It is for people who are stable now and take certain medications.
Paris, ParisAges 18–60 - NCT06611878Recruiting
Music training for Alzheimer's patients at home
This trial tests whether intensive music training can help memory in people with Alzheimer's disease who live at home and are not musicians.
Buenos AiresAges 65 years+ - NCT06617312RecruitingPhase 2
Cytisinicline and brain response to smoking cues
This study tests how a medicine called cytisinicline (similar to a plant-based stop-smoking aid) affects brain activity when you see or think about smoking. It may help researchers understand how the medicine works, even if you aren't ready to quit right now.
Los Angeles, CaliforniaAges 18–65 - NCT06608706Recruiting
Integrated trauma treatment for psychosis
This trial tests a new way to treat trauma in people who have psychosis (like schizophrenia). It combines therapy for trauma with your usual care, and aims to help you feel less distressed by past traumatic events.
BergenAges 16 years+ - NCT06603064Recruiting
Brain stimulation study on stress and emotions
This study uses brain scans to understand how your brain responds to stress. You will complete tasks and answer questions while undergoing an MRI to help researchers learn more about emotional responses.
Pittsburgh, PennsylvaniaAges 30–50 - NCT06605001Recruiting
Development, attention, and inhibition study
This study looks at how children develop attention and self-control. It may help us understand typical growth and learning.
Davis, CaliforniaAges 4–7 - NCT06605469Recruiting
Ejaculation and orgasm problems registry
This study creates a registry for men being treated for ejaculation or orgasm problems, and for their partners. It aims to collect information that could help improve care.
Orem, UtahAges 18 years+ - NCT06609083RecruitingPhase 1
How cannabis affects cigarette smoking
This study looks at how cannabis affects cigarette smoking habits. If you smoke every day and also use cannabis weekly, researchers want to see if cannabis changes how much you smoke.
Baltimore, MarylandAges 21 years+ - NCT06605508Recruiting
Stem cell injection for erectile dysfunction
This trial tests whether injecting stem cells or their byproducts can help men with erectile dysfunction who haven't responded well to standard treatments like Viagra. It aims to find a new option for improving sexual function.
Dubai, DubaiAges 30–75 - NCT06616324Recruiting
Virtual reality to reduce pain during kidney stone treatment
This study tests whether using a virtual reality (VR) headset during a kidney stone treatment called ESWL can help reduce pain and anxiety. If you're scheduled for ESWL at a hospital in Region Zealand, you may be able to use VR to distract yourself during the procedure.
RoskildeAges 18 years+ - NCT06604104Recruiting
Visual Frailty Study in Older Adults with AMD
This study looks at something called 'visual frailty' in older adults with advanced age-related macular degeneration (AMD). It aims to develop a tool to better understand how vision loss affects daily life and overall health in people aged 60 and over.
Edinburgh, ScotlandAges 60 years+ - NCT06609369RecruitingPhase 2
Sleep and smoking relapse study
This study tests whether improving sleep can help people quit smoking and avoid relapse. It uses brain scans, a quitting medication, and counseling.
New Haven, ConnecticutAges 18–65 - NCT06614868Recruiting
Stress counseling for LGBTQ+ individuals
This study tests a counseling program designed to help LGBTQ+ people cope with stress related to their identity. It may help you if you're looking for support dealing with the unique challenges of being a sexual minority.
Birmingham, AlabamaAges 18 years+
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,780 recruiting psychiatry studies from the U.S. registry right now, out of 12,430 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.