Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,771 recruiting studies in this area right now.
By phase
- Not applicable6,421
- Phase 2492
- Phase 1248
- Phase 3237
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 367
Top conditions
- Anxiety388
- Depression381
- Alzheimer Disease338
- Autism Spectrum Disorder240
- Dementia225
- Mild Cognitive Impairment194
- Schizophrenia184
- Major Depressive Disorder174
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder142
- Opioid Use Disorder141
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Mild Cognitive Impairment (MCI)88
- Suicidal Ideation87
Leading sponsors
- VA Office of Research and Development105
- Yale University86
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University61
- University of California, Los Angeles58
- The University of Hong Kong51
- University of Pennsylvania51
- Karolinska Institutet50
Where studies are running
- California517
- Massachusetts265
- New York255
- Texas209
- Maryland175
- Pennsylvania169
- Florida145
- Alabama118
- Arizona109
- Illinois103
Recruiting studies7,771 total
- NCT07780383RecruitingPhase 1
Single-dose study for healthy adults and early Alzheimer's participants
This trial tests a new investigational drug, BMS-986446, given as a single dose to healthy volunteers and multiple doses to people with early Alzheimer's disease. It aims to understand how the drug moves in the body, its safety, and whether it triggers an immune response, which could help guide future treatment for Alzheimer's.
Anaheim, CaliforniaAges 18–80 - NCT05509387Recruiting
Stronger brain stimulation to improve naming in Alzheimer’s
This trial tests whether a stronger form of gentle brain stimulation (tDCS) can help people with mild to moderate Alzheimer’s improve word-finding (naming). If you qualify, you’ll be assessed before and during the study to see whether the stimulation improves naming ability.
Toronto, OntarioAges 50–90 - NCT07783516Recruiting
Brazilian Jiu-Jitsu for trauma relief in first responders
This study tests whether Brazilian Jiu-Jitsu classes, taken twice a week, can help first responders cope with trauma-related stress. You'll learn self-defense and mindfulness while tracking your stress levels.
Conroe, TexasAges 18 years+ - NCT07781943Recruiting
Breathing exercises to reduce anxiety before gastroscopy
This study tests whether doing simple breathing exercises before a gastroscopy (a tube test of the stomach) can help reduce fear, anxiety, and changes in heart rate or blood pressure. It may help you feel more relaxed and comfortable during the procedure.
FamagustaAges 18 years+ - NCT07775937Recruiting
Social robots and board games for children with autism
This study tests whether playing with a social robot called Kebbi Air and board games can help children with autism improve their social and emotional skills. If your child enjoys interactive toys and can follow simple instructions, this may be a good fit.
Huwei, YunlinAges 4–10 - NCT07778394Recruiting
Smartphone app to support recovery from opioid use disorder
This study is testing a smartphone app to help people who are starting or restarting medication for opioid use disorder. If you join, you'll use the app to support your recovery journey.
Providence, Rhode IslandAges 22 years+ - NCT07780331Recruiting
Virtual reality and games to reduce fear in children using inhalers
This study tests whether using virtual reality glasses or playing games on a tablet can help reduce fear and anxiety in young children (aged 4-6) when they need to take medication through an inhaler or nebulizer. It aims to see if these distractions make the experience more comfortable.
Balıkesir, BalıkesirAges 4–6 - NCT07781670Recruiting
Brain and body responses to physical and emotional stress
This study looks at how your brain and body (heart rate, etc.) respond to sudden physical and emotional stress. You will do tasks like placing your hand in cold water or viewing emotional images while we record your brain activity with EEG. The results may help understand how stress affects health.
Pavia, LombardyAges 18 years+ - NCT07777328Recruiting
5-HTP for ADHD traits and eye movements in adults
This study looks at how a supplement called 5-HTP (a natural amino acid) affects attention and eye movements in adults. You will receive either 5-HTP or a placebo to see if it changes ADHD-like traits.
Sheffield, South YorkshireAges 18–65 - NCT07782398Recruiting
Smartphone stress prompts and hair steroid levels in college students
This study tests whether brief prompts to help you cope with stress, sent to your smartphone, can improve your wellbeing. It will also look at stress hormones in hair as a way to measure long-term stress levels.
Gainesville, FloridaAges 18–89 - NCT07779759Recruiting
Speech therapy intensity for children with speech sound disorders
This study compares two different levels of speech therapy (high-intensity versus low-intensity) to see which is more effective for children aged 4 to 12 who have difficulty making certain speech sounds correctly.
GhentAges 4–12 - NCT07783958Recruiting
Sexual function and quality of life in polygamous versus monogamous marriages
This study looks at how being in a polygamous versus monogamous marriage affects sexual function and quality of life in Egyptian men. Participants will be asked to fill out an anonymous online questionnaire.
CairoAges 18 years+ - NCT07781566Recruiting
Speech therapy intensity for cleft palate speech errors in children
This study looks at how well two different intensities of speech therapy work for children with a cleft palate who have speech sound errors. It aims to find the best way to help your child speak more clearly.
Ghent, East-FlandersAges 4 years+ - NCT07780097Enrolling by invitation
Starting opioid addiction medication after a hospital stay
This study helps people who are in the hospital for opioid use disorder start a medication like methadone or buprenorphine after they leave the hospital. It aims to make starting treatment easier and improve recovery.
Cincinnati, OhioAges 18 years+ - NCT07778511Recruiting
How opioids affect stress and social behavior
This study looks at how opioid medicines affect stress and social behavior in healthy men and women, and whether childhood experiences play a role. Participation involves taking a study drug and giving blood samples.
ZurichAges 18–40 - NCT07775833Recruiting
Mushroom supplement to slow memory decline in at-risk adults
This trial tests whether eating mushrooms regularly can help prevent memory loss in people who are at higher risk for Alzheimer's disease but do not have dementia. If you are between 45 and 80, have some memory concerns, and currently eat mushrooms rarely, this study may be a good fit.
SingaporeAges 45–80 - NCT07778134Recruiting
Personalized storybook for better dental visits in children
This study tests whether a personalized storybook (created with AI) helps reduce anxiety and improve cooperation in children during dental fillings. It may help kids who are nervous about dental visits feel more at ease.
EskişehirAges 4–7 - NCT07783633Enrolling by invitation
Digital tools for mood disorders study
This study looks at whether using digital tools, like apps or online programs, can help people with mood disorders like depression or bipolar disorder. It aims to find markers that show who might benefit most from these tools.
Toronto, OntarioAges 16 years+ - NCT07779707Recruiting
Healthy groceries for people with depression and food needs
This study gives free, healthy groceries made to match your health needs and offers support to help improve your mood and reduce stress. It aims to see if getting nutritious food can help people with depression feel better.
Worcester, MassachusettsAges 18 years+ - NCT07779889Recruiting
Movement and wellness study for school-age children
This study tests a special program called the Melillo Method, which uses movements and activities to help children feel better emotionally, socially, and in school. It may help children who are struggling with behavior or emotions.
Roodhouse, IllinoisAges 8 years+ - NCT07783464Recruiting
Heart rate variability and delirium after major abdominal surgery in older adults
This study looks at whether heart rate variability (a measure of your heart's ability to adapt to stress) can help predict delirium (confusion or disorientation) after major abdominal surgery in older adults. You may qualify if you are 65-85 years old, having major abdominal surgery, and do not have serious heart, nervous system, or memory problems.
Nanjing, JiangsuAges 65–85 - NCT03764748RecruitingPhase 1
Washed stool transplant for Tourette syndrome in kids
This Phase 1 study tests whether a “washed” stool microbiota transplant can reduce Tourette syndrome tics in children. It aims to see if changing gut bacteria is safe and may improve tic severity.
Nanjing, JiangsuAges 6–17 - NCT04477434Recruiting
Study of electroconvulsive therapy (ECT) patients in France
This trial follows people who have been referred for electroconvulsive therapy (ECT), a treatment used for certain severe mental health conditions. The study aims to learn about how ECT is used in real-world care and what outcomes may look like for patients.
AngersAges Any age - NCT06446479RecruitingPhase 2
THC's effect on alcohol use and brain reward
This study tests whether THC (the active ingredient in cannabis) can change how much alcohol you drink and how your brain responds to rewards. You will have MRI scans and take THC or a placebo, then drink alcohol in a controlled setting.
Aurora, ColoradoAges 21–40
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,771 recruiting psychiatry studies from the U.S. registry right now, out of 12,314 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.