Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 8,195 recruiting studies in this area right now.
By phase
- Not applicable6,798
- Phase 2512
- Phase 1258
- Phase 3245
- Phase 4213
- Phase 1/Phase 298
- Phase 2/Phase 371
Top conditions
- Depression422
- Anxiety415
- Alzheimer Disease341
- Autism Spectrum Disorder258
- Dementia226
- Mild Cognitive Impairment199
- Schizophrenia192
- Major Depressive Disorder189
- Cognitive Impairment157
- Insomnia152
- Alcohol Use Disorder150
- Opioid Use Disorder145
- Stress136
- PTSD110
- Autism95
- Mental Health92
- Suicidal Ideation92
- Anxiety Disorders85
Leading sponsors
- VA Office of Research and Development103
- Yale University95
- Massachusetts General Hospital78
- Stanford University72
- Assistance Publique - Hôpitaux de Paris65
- Johns Hopkins University63
- University of California, Los Angeles61
- The University of Hong Kong52
- University of Pennsylvania51
- Karolinska Institutet50
Where studies are running
- California530
- New York268
- Massachusetts263
- Texas223
- Maryland176
- Pennsylvania175
- Florida153
- Alabama118
- Arizona117
- Connecticut113
Recruiting studies8,194 total
- NCT07750236Recruiting
Stress ball for easing fear and pain during allergy testing
This trial gives children a stress ball to hold during their allergy skin test, to see if it helps reduce fear, anxiety, and pain, and makes the experience more satisfying for the family.
TarsusAges 4–10 - NCT07222306Enrolling by invitation
Cannabis, brain inflammation, and suicidal thoughts brain imaging study
This study uses brain scans to see how cannabis affects inflammation and suicidal thoughts. You may join if you're already in a related study and can safely undergo MRI and PET scans.
Detroit, MichiganAges 19–69 - NCT06233344RecruitingPhase 2
Mindfulness and psilocybin study for healthy adults
This study tests whether combining mindfulness training with a single dose of psilocybin (a psychedelic found in certain mushrooms) can help healthy adults. It aims to explore how these two approaches together might improve well-being.
Los Angeles, CaliforniaAges 25 years+ - NCT05879211Enrolling by invitation
Care learning lab for Duke Health patients
This trial is a “learning laboratory” that studies how best to provide goal-focused care. It may help improve care experiences for Duke Health patients, based on what the study learns.
Durham, North CarolinaAges 18 years+ - NCT07623135RecruitingPhase 3
Lumateperone for Hard-to-Treat Depression in Older Adults
This study tests lumateperone, a new medication added to your current antidepressant, to help treat depression that hasn't improved with other treatments. It's designed for people age 60 and older who have tried at least two antidepressants without success.
Tucson, ArizonaAges 60 years+ - NCT07412756RecruitingPhase 3
Brenipatide for major depressive disorder
This trial tests a new medication, Brenipatide, to see if it helps people with major depression who are already on a stable treatment. You would need to inject the study drug yourself and complete questionnaires.
Moorpark, CaliforniaAges 18–75 - NCT07293494Recruiting
Spaceflight stress and brain changes study
This study looks at how the stress of spaceflight affects the brain and behavior. You will complete tasks and have MRI scans while staying in a controlled environment, including some sleep disruption and alcohol consumption.
Philadelphia, PennsylvaniaAges 21–60 - NCT07410507RecruitingPhase 2
Study of Brenipatide for adults with schizophrenia
This trial tests an investigational drug called brenipatide for people with schizophrenia who are already on a stable medication regimen. The goal is to see if adding this drug helps reduce relapses.
Little Rock, ArkansasAges 18–55 - NCT07474974Recruiting
Can Eye Cells Predict TMS Success for Depression?
This study tests whether a specific type of eye cell can predict how well transcranial magnetic stimulation (TMS) works for treating depression. TMS is a non-invasive brain stimulation method that may help people with depression that hasn't responded to other treatments.
Porto, Porto DistrictAges 18–65 - NCT07219953RecruitingPhase 3
Testing brenipatide for alcohol use disorder
This study tests an experimental medicine called brenipatide to help people reduce or stop drinking. It involves getting a daily injection and completing check-ins and questionnaires over several months.
Scottsdale, ArizonaAges 18–75 - NCT07216716Recruiting
Health app recommendation tool for Alzheimer's caregivers
This study tests a tool that helps find health apps for people caring for a loved one with Alzheimer's or a related dementia. It aims to see if the tool makes it easier to choose useful apps for your caregiving journey.
Pittsburgh, PennsylvaniaAges 18–65 - NCT07607613Recruiting
Support for LGBTQ+ Parents with Depression Risk
This study offers group support sessions for LGBTQ+ parents who are pregnant or recently had a baby and are experiencing mild depression or worry about postpartum depression. The goal is to help prevent depression from getting worse and improve emotional well-being during this important life transition.
Chicago, IllinoisAges 18 years+ - NCT07505381Recruiting
Parent training for child behavior (ages 0-12)
This study tests two parent training programs (HOT DOCS and DOCS K-5) that teach skills to help manage young children's disruptive behavior. It's for caregivers or professionals who speak English or Spanish and care for a child up to 12 years old.
Tampa, FloridaAges 18 years+ - NCT07284667RecruitingPhase 2
A new medicine for depression that hasn't improved with other treatments
This trial tests a new medicine called ACP-211 in adults with major depression who have not gotten enough relief from at least two previous antidepressants. The goal is to see if it can help when other treatments have not worked well.
Birmingham, AlabamaAges 18–65 - NCT05368493Enrolling by invitation
Study how air pollution affects youth development
This study looks at whether exposure to air pollution during youth is linked to how children grow, learn, or develop. You may be invited if your family is already part of an earlier birth cohort study and can complete questionnaires and (if needed) brain imaging safely.
New York, New YorkAges 6 months–11 years - NCT07227987Recruiting
Cognitive rehab for anger in Veterans with TBI and PTSD
This study tests a cognitive rehabilitation program to help Veterans with TBI and PTSD manage anger. You and a trusted support person will participate together to learn skills to reduce anger and improve thinking.
Durham, North CarolinaAges 18 years+ - NCT07750639Enrolling by invitationPhase 4
Reducing painkiller use after hand surgery
This study tests a new approach to prescribing fewer opioid pain pills after hand, wrist, or elbow surgery. It aims to help reduce the risk of opioid misuse while still controlling pain after surgery.
Orlando, FloridaAges 18 years+ - NCT06907654Recruiting
Couples' affect and relationships study
This study looks at how couples' moods and relationships interact over time. You and your partner will use a smartphone app and respond to daily text surveys for 3 weeks.
Madison, WisconsinAges 18 years+ - NCT07032480Recruiting
Sleep, Neck Pain, and Depression Study
This study looks at how sleep problems, neck pain, and depression might be connected in healthy young adults. It aims to help understand these common issues better.
Istanbul, ÜsküdarAges 18–28 - NCT07021053Recruiting
Online therapy for alcohol use: a Canadian study
This trial tests an internet-delivered cognitive behaviour therapy program for people who drink more than they'd like. It aims to see how your daily actions and decisions affect your drinking habits and help you make changes.
Regina, SaskatchewanAges 18 years+ - NCT07044154Recruiting
Sun Tai Chi for heart, lung, and mental health in college students
This trial tests whether a gentle Sun-style Tai Chi program can improve your heart and lung fitness as well as your mental well-being if you have mild to moderate stress, anxiety, or depression. It's for university students who are not already very active and who are not taking mental health medicines.
Talca, Maule RegionAges 18–29 - NCT07066605Recruiting
Dexmedetomidine for agitation during breathing tube removal
This trial tests whether a sedative called dexmedetomidine can reduce agitation in ICU patients when they are being weaned off a breathing tube. If you experience restlessness or agitation during the weaning process, this medication might help you stay calm.
SohagAges 19 years+ - NCT07068685Enrolling by invitation
Testing a suicide risk tool in primary care
This study is testing a computer program that helps doctors spot people who might be at risk for suicide. If you have a primary care visit at Kaiser Permanente Washington, the program will use your health records to see if you could benefit from extra support.
Seattle, WashingtonAges 18 years+ - NCT07006324Recruiting
Home visits for high-risk postpartum parents in Mississippi Delta
This program offers home visits after childbirth for mothers and parents in the Mississippi Delta who had a high-risk pregnancy. It aims to provide support and care to help you and your baby stay healthy.
Jackson, MississippiAges 18–45
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 8,195 recruiting psychiatry studies from the U.S. registry right now, out of 13,258 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.