Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,779 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1250
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease338
- Autism Spectrum Disorder239
- Dementia228
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder143
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Mild Cognitive Impairment (MCI)89
- Suicidal Ideation89
Leading sponsors
- VA Office of Research and Development104
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- Karolinska Institutet51
- The University of Hong Kong51
Where studies are running
- California520
- Massachusetts267
- New York255
- Texas209
- Maryland176
- Pennsylvania170
- Florida149
- Alabama118
- Arizona109
- Illinois104
Recruiting studies7,779 total
- NCT05995678Recruiting
STEP Home Workshop for veterans adjusting to civilian life
This pilot study tests a workshop called STEP Home to help veterans who recently left the military and are having trouble readjusting. The goal is to improve their transition and reduce suicide risk.
Boston, MassachusettsAges 18–65 - NCT06000475Recruiting
Memory boosting therapy for PTSD in veterans
This trial is testing a type of therapy called Cognitive Processing Therapy (CPT) for PTSD, along with memory exercises to help enhance the therapy's effects. It is for veterans who have PTSD and want to see if adding memory training can improve their treatment.
Philadelphia, PennsylvaniaAges 60 years+ - NCT05974631Recruiting
Treatments for suicidal Veterans with PTSD
This study tests two types of therapy to help Veterans with PTSD who are struggling with suicidal thoughts and self-harm. It compares a treatment called DBT (Dialectical Behavior Therapy, which helps with emotions) with another called PE (Prolonged Exposure, which helps with trauma).
Minneapolis, MinnesotaAges 18 years+ - NCT05989841RecruitingPhase 1/Phase 2
Helping women after sexual assault who use cannabis
This study tests a new approach to help women who have recently experienced a sexual assault and use cannabis. It explores whether reducing anxiety about physical symptoms can help prevent long-term PTSD and cannabis problems.
Minneapolis, MinnesotaAges 18 years+ - NCT05987774Recruiting
AI program to improve social conversation skills in autism
This study tests a computer-based AI program that helps people with autism practice and improve social conversation skills. It's designed for those who can already speak in sentences but want to get better at specific areas like empathy.
Stanford, CaliforniaAges 3–35 - NCT05987735Enrolling by invitation
Blame-Less program for trauma-related shame and guilt
This study tests a 7-week psychoeducation program called BLAME-LESS to help people who feel guilt or shame after a traumatic event. It aims to reduce these feelings by providing clear information on trauma responses.
Almelo, OverijsselAges 12–18 - NCT05998031Recruiting
Testing brain stimulation for memory in mild memory loss
This study tests if a gentle brain stimulation technique called tDCS, combined with memory training, can help older adults with mild cognitive impairment (MCI) improve their working memory. You'll have MRI scans and attend training sessions.
Gainesville, FloridaAges 60–95 - NCT05977439Recruiting
Brain training for depression recovery
This study uses brain imaging and stimulation to help people with depression learn how to regulate their emotions better. It aims to find out if targeting specific brain networks can improve symptoms.
Charleston, South CarolinaAges 18–65 - NCT05988515Recruiting
AI-assisted treatment for children struggling with the 'r' sound
This study tests a computer-assisted program to help children and teens improve their 'r' sound. It is designed for those who struggle with saying 'r' and want to work on it through online sessions.
Syracuse, New YorkAges 9–17 - NCT05999929Recruiting
Memory support system feasibility trial
This study tests a memory support system for people with mild cognitive impairment (MCI) and their care partners. It aims to see if the program is practical and helpful for managing memory challenges.
Ottawa, OntarioAges 50 years+ - NCT05999383RecruitingPhase 2
Marijuana and tobacco use study
This trial looks at how marijuana and tobacco work together in your body. If you regularly use both cannabis and tobacco, you may help researchers understand their combined effects.
San Francisco, CaliforniaAges 21–65 - NCT05995886Recruiting
Facebook support group for American Indian women in opioid recovery
This study tests if a private Facebook group can help American Indian women in Minnesota stay in recovery from opioid use disorder. You must be on medication for opioid use and have stable recovery for at least a month to take part.
Rochester, MinnesotaAges 18 years+ - NCT05974176Recruiting
Study on stress, trauma symptoms, and family support
This study looks at how racial and cultural stress may affect trauma-related emotional reactions in children and their parents/guardians. It may help researchers understand what kinds of support work best for families dealing with trauma.
New York, New YorkAges 5–17 - NCT05988710RecruitingPhase 4
Low-dose buprenorphine for pain in opioid-naive adults
This study tests a low-dose form of buprenorphine (a medicine for pain) placed inside the cheek. It is designed for people who have never taken opioids before, to see how well it works for pain and how likely it is to be misused.
Nashville, TennesseeAges 18–65 - NCT05973942Enrolling by invitation
Study of Wingman-Connect using Air Force base data
This study looks at how a program called Wingman-Connect affects people across certain U.S. Air Force bases. It uses existing data from multiple bases rather than testing a treatment on individual volunteers.
Rochester, New YorkAges 18 years+ - NCT05995535RecruitingPhase 2
Pregabalin and Lofexidine for Opioid Withdrawal
This study tests whether combining two medications, pregabalin and lofexidine, can help people stop using opioids by easing withdrawal symptoms. It's for adults who use opioids heavily and want to switch to a non-addictive blocker medication.
Baltimore, MarylandAges 18 years+ - NCT05999240RecruitingPhase 2
Pimavanserin for rigid-compulsive symptoms in autism
This trial tests if the drug pimavanserin can help reduce rigid or repetitive behaviors in people with autism spectrum disorder. It may be an option if you or your child struggle with these symptoms and want to try a new treatment.
Lawrence, KansasAges 12–40 - NCT05973838Recruiting
Telemedicine support plus recovery coaching for multiple drug use
This study tests whether adding peer recovery support to a phone/video treatment program helps people stay in treatment longer and reduce polysubstance use. It focuses on adults in opioid use disorder care who have used other non-prescribed substances in the last three months.
Washington D.C., District of ColumbiaAges 18 years+ - NCT05996900Recruiting
Brain stimulation study for adults with epilepsy
This study uses advanced brain monitoring and noninvasive magnetic stimulation to understand how repetitive brain stimulation works in people with epilepsy who are already scheduled for hospital monitoring. It may help develop better treatments for seizures.
Stanford, CaliforniaAges 18–65 - NCT05988632RecruitingPhase 1/Phase 2
Insulin nasal spray for alcohol use disorder
This trial tests whether a nasal spray with insulin can help people with alcohol use disorder. It may affect how the brain responds to alcohol and reduce drinking.
Providence, Rhode IslandAges 21 years+ - NCT05989646Recruiting
Brain activity study in children with overactive bladder
This study looks at brain activity in children with overactive bladder and daytime wetting compared to healthy children. It uses MRI scans to understand how the brain controls the bladder, which could lead to better treatments.
AalborgAges 6–14 - NCT05997030Recruiting
Gentle Ultrasound for Alzheimer's Memory Problems
This study tests whether gentle, low-intensity ultrasound waves focused on certain brain areas can help people with early memory loss from Alzheimer's disease. It is a non-invasive treatment that might improve brain function without surgery.
Morgantown, West VirginiaAges 45–85 - NCT05988996Enrolling by invitation
Peer support groups for NICU families
This trial is testing a peer support group program for parents of babies in the NICU. It aims to help families feel supported and connected during a stressful time.
Portland, OregonAges 18–70 - NCT05994612Recruiting
Suicide prevention for homeless youth using substances
This trial tests a program to help reduce suicide risk in young people who are homeless and use alcohol or drugs. It may provide support and strategies to keep them safe.
Columbus, OhioAges 15–24
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,779 recruiting psychiatry studies from the U.S. registry right now, out of 12,461 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.