Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,779 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1250
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease338
- Autism Spectrum Disorder239
- Dementia228
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder143
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Mild Cognitive Impairment (MCI)89
- Suicidal Ideation89
Leading sponsors
- VA Office of Research and Development104
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- Karolinska Institutet51
- The University of Hong Kong51
Where studies are running
- California520
- Massachusetts267
- New York255
- Texas209
- Maryland176
- Pennsylvania170
- Florida149
- Alabama118
- Arizona109
- Illinois104
Recruiting studies7,779 total
- NCT05372172Recruiting
Tennessee Alzheimer’s study for people 60 and older
This study is looking at how brain and memory changes show up in people across the Alzheimer’s spectrum—from normal thinking to mild memory problems to Alzheimer’s disease. You might join if you can do study visits and an MRI and have a reliable study partner available.
Nashville, TennesseeAges 60 years+ - NCT05369429Recruiting
Stress and mood support program for adults with cancer
This trial tests a new online “wellbeing guide” to help manage stress and improve quality of life. It focuses on adults with cancer who also have higher-than-usual depressive symptoms.
Chicago, IllinoisAges 18 years+ - NCT05396248Recruiting
Memory training study for older adults with mild memory problems
This trial tests an approach to improve learning and memory in people age 60+ with amnestic mild cognitive impairment (a specific type of early memory problem). It may help by supporting memory and learning skills, but it also has medication and health-history requirements.
Ann Arbor, MichiganAges 60 years+ - NCT05400382Recruiting
Mindfulness for depression and pain after cesarean delivery
This study tests whether a mindfulness program can help new mothers manage pain and depression after a planned cesarean delivery. You might be eligible if you are a woman of color or non-Hispanic White with a history of depression and are scheduled for a planned C-section.
Champaign, IllinoisAges 18–45 - NCT05393830Recruiting
Study tests how sleep loss affects emotion control
This study looks at how losing sleep changes a person’s ability to manage emotions. You may need to do brain scans (fMRI), and you would be asked to avoid alcohol and recreational drugs during the study.
Boston, MassachusettsAges 18–40 - NCT05388565Recruiting
Support program for early pregnancy after intimate partner violence
This trial tests an enhanced perinatal care (pregnancy and newborn support) program for people who are pregnant early and have been screened positive for intimate partner violence. It may help by offering extra support and care tailored to safety and pregnancy needs.
Jinan, ShandongAges 18 years+ - NCT05395949Enrolling by invitation
Treat breast inflammation with support for mental health
This study looks at a non-surgical (“conservative”) approach to treating granulomatous lobular mastitis, along with help for mental health symptoms. It may help people whose breast inflammation and mental health concerns happen together.
Wuhan, HubeiAges 18–60 - NCT05377125Recruiting
Training brain skills to reduce urges in OCD spectrum
This study tests a training program meant to improve “response inhibition,” the brain’s ability to pause before acting on unwanted urges. It may help people with OCD-spectrum conditions like obsessive-compulsive disorder, trichotillomania (hair pulling), or skin picking by targeting brain control of impulses.
Milwaukee, WisconsinAges 18–60 - NCT05411029Recruiting
Study on sleep problems in Somali adults
This study looks at how disrupted sleep shows up in Somali adults without certain health conditions. It may help researchers understand sleep patterns in this community and improve future sleep support.
Rochester, MinnesotaAges 18–70 - NCT05393492Recruiting
Emotion and behavior skills after a brain injury
This study tests a structured program to help people after a brain injury manage emotions and challenging behaviors, and to reduce distress for them and their families. If you (or your family member) can participate safely and understand the activities in French, you may be invited to join a group and assessments.
Illkirch-GraffenstadenAges 18 years+ - NCT05370391Recruiting
Behavior therapy for youth tics with parent involvement
This study tests a structured behavior-based therapy (CBIT) to help reduce tic symptoms that interfere with daily life. You and a parent/caregiver work together during visits and questionnaires to see if treatment helps.
Coral Gables, FloridaAges 5–17 - NCT05384158Recruiting
Testing a computer game for low mood, low pleasure, or anxiety
This trial looks at how a computer-based task performs when someone is dealing with depression-like symptoms, such as low mood, low interest/pleasure, or anxiety that affects daily functioning. You might find it helpful if you fit their symptom and safety requirements and are comfortable with computer tasks and (for some parts) MRI scanning.
Roanoke, VirginiaAges 25–50 - NCT05388864Recruiting
Parenting support program for young children and families
This study offers a parenting support program for families with children ages 3 to 11. It aims to help strengthen family routines and child well-being by teaching practical skills.
Loma Linda, CaliforniaAges 3–11 - NCT05398484RecruitingPhase 2/Phase 3
Psilocybin therapy for advanced cancer-related anxiety
This trial studies whether psilocybin (with support and therapy) can reduce anxiety in people with advanced cancer. It may help with distress and quality of life, while the study team monitors safety closely.
Aurora, ColoradoAges 21–100 - NCT05398276Recruiting
Coaching for exercise anxiety through body-sensation exposure
This study tests whether a behavioral training approach that helps you become more comfortable with body sensations during exercise can reduce exercise anxiety. It may help people who are less active because they feel anxious when exercising.
East Brunswick, New JerseyAges 40 years+ - NCT05375513Recruiting
Home-based program to boost memory and thinking
This study tests a program that combines exercise, diet advice, and memory training, all done from home, to help improve thinking and memory in older adults with mild memory problems. You'll be asked to use a computer or tablet for virtual sessions and follow a simple plan.
Edmonton, AlbertaAges 60–85 - NCT05384392Recruiting
Blood and brain-marker study after a first psychotic episode
This study looks at whether special body and brain markers can predict how a person’s symptoms change over two years after a first psychotic episode. It may also help doctors understand who responds better to treatment, so future care can be more personalized.
AngersAges 15–30 - NCT05401929Recruiting
TMS to reduce cannabis use in heavy users
This study tests whether transcranial magnetic stimulation (TMS) can help heavy cannabis users cut down or stop. TMS uses a magnetic coil on the scalp to gently stimulate parts of the brain involved in cravings and habits.
Durham, North CarolinaAges 18–65 - NCT05327504Recruiting
Writing therapy for PTSD and substance use in veterans
This study tests a structured “written exposure” therapy to help veterans with PTSD who also have a substance use disorder (SUD). It may help reduce PTSD symptoms while also supporting safer, more stable recovery.
West Haven, ConnecticutAges 18 years+ - NCT05325645RecruitingPhase 3
Once-weekly brexpiprazole for acute schizophrenia
This trial tests a new once-weekly version of the medication brexpiprazole, which is designed to relieve symptoms of schizophrenia. If you have experienced symptom flare-ups despite being on antipsychotic medication, this study might help you manage your symptoms.
Kure-shiAges 18–74 - NCT05331937RecruitingPhase 3
TMS plus exposure therapy for severe OCD that won’t improve
This trial studies whether TMS (a brain stimulation treatment) can help people with severe OCD who have not responded well to exposure therapy. It combines brain stimulation with intensive exposure therapy to reduce obsessions and compulsions.
Amsterdam, North HollandAges 18 years+ - NCT05354622Recruiting
Genetic testing study for inherited leg stiffness
This study looks at genes (DNA) to understand an inherited condition that causes gradually worsening leg stiffness. It may help researchers learn what causes the condition and potentially guide future care.
Boston, MassachusettsAges 1 month–30 years - NCT05326750Recruiting
Brain stimulation to help diagnose and manage memory conditions
This trial studies a non-invasive brain-stimulation approach to help doctors assess and manage certain brain-related conditions. You might benefit by contributing to better diagnostic tools and treatment planning for memory and thinking problems.
KuopioAges 18 years+ - NCT05324254Recruiting
Weighted blankets to help after breast surgery pain
This study tests whether sleeping with a weighted blanket can reduce pain after breast surgery. You may use a smartphone app to quickly report how your pain and comfort feel over time for up to 3 months.
La Jolla, CaliforniaAges 18 years+
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,779 recruiting psychiatry studies from the U.S. registry right now, out of 12,461 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.