Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 8,192 recruiting studies in this area right now.
By phase
- Not applicable6,797
- Phase 2511
- Phase 1258
- Phase 3244
- Phase 4213
- Phase 1/Phase 298
- Phase 2/Phase 371
Top conditions
- Depression420
- Anxiety412
- Alzheimer Disease342
- Autism Spectrum Disorder258
- Dementia226
- Mild Cognitive Impairment199
- Schizophrenia192
- Major Depressive Disorder188
- Cognitive Impairment157
- Insomnia152
- Alcohol Use Disorder150
- Opioid Use Disorder145
- Stress136
- PTSD110
- Autism95
- Mental Health92
- Suicidal Ideation92
- Anxiety Disorders85
Leading sponsors
- VA Office of Research and Development104
- Yale University95
- Massachusetts General Hospital78
- Stanford University72
- Assistance Publique - Hôpitaux de Paris65
- Johns Hopkins University63
- University of California, Los Angeles61
- The University of Hong Kong52
- University of Pennsylvania52
- Karolinska Institutet50
Where studies are running
- California529
- New York267
- Massachusetts263
- Texas223
- Maryland176
- Pennsylvania175
- Florida153
- Alabama118
- Arizona117
- Connecticut113
Recruiting studies8,191 total
- NCT05713669Recruiting
Clinic follow-up after ICU care with resident involvement
This study looks at whether having medical trainees (residents) participate in a follow-up clinic after an ICU stay affects patient care and follow-up. You may be eligible if you’re connected to the ICU follow-up clinic and had no death during your ICU stay.
Ann Arbor, MichiganAges 18 years+ - NCT05855720Recruiting
Study of flexible care plans across hospitals
This study compares how flexible, integrated treatment projects are carried out across different hospitals nationwide. It’s mainly looking at what happens in routine care, so it may help improve how future care is organized.
MagdeburgAges Any age - NCT05815199Recruiting
E-cigarettes to help smokers with serious mental illness cut down
This study tests whether e-cigarettes can help people who smoke a lot reduce cigarette use (without requiring them to quit completely). It is designed for adults with serious mental illness and focuses on harm reduction and follow-up over time.
New York, New YorkAges 21 years+ - NCT05728138Recruiting
Talk therapy trial for suicidal thoughts in early psychosis
This study tests a psychosocial (talk-based) intervention for people with early psychosis who are having thoughts about death or being better off dead. It aims to see if the approach is safe and workable, and whether it can help reduce suicidal thinking.
Karachi, SindhAges 18 years+ - NCT05696691RecruitingPhase 2/Phase 3
Ketamine with a crisis plan for suicidal thoughts in the ER
This study tests whether ketamine plus a structured crisis-response plan can help reduce suicidal thoughts for adults admitted from the ER. It also aims to make care in the emergency setting more consistent and effective.
San Antonio, TexasAges 18–70 - NCT05840900Recruiting
Mindfulness and optimism program for first-time pregnancy wellbeing
This study tests a mindfulness- and optimism-focused program to support wellbeing and resilience during pregnancy. It may help people, especially those who naturally feel less optimistic, learn stress-support skills during early pregnancy.
Providence, Rhode IslandAges 18 years+ - NCT05642897Recruiting
Mind program for women receiving breast cancer radiotherapy
This trial tests a “Mind Programme” designed to support women with breast cancer who are currently receiving radiation treatment. It may help with emotional well-being during radiotherapy, but you must meet specific health and language requirements.
CoimbraAges 18–70 - NCT05834660Recruiting
School suicide prevention support for teens and caregivers
This trial tests a support program used in participating schools to help teens who have suicide thoughts or have acted on them, with their caregiver’s involvement. It aims to improve safety and outcomes after the school notices the concern.
Los Angeles, CaliforniaAges 11 years+ - NCT05572671Recruiting
Study brain scans to predict near-term smoking relapse risk
This study uses MRI brain scans and smoking measurements to understand what may predict when someone is about to smoke again. If you qualify, you’ll be asked to avoid nicotine for 12 hours before a lab visit and complete MRI safety screening.
University Park, PennsylvaniaAges 21–65 - NCT05533138Recruiting
Online therapy to treat depression during pregnancy
This trial tests an internet-based version of CBT, a structured talking therapy, for depression during pregnancy. It may help by teaching practical skills to reduce depressive symptoms while you stay connected to your maternity mental health clinic.
StockholmAges 18 years+ - NCT05359562Recruiting
Hormones and OCD treatment approach on the brain
This study looks at how hormone changes and a specific OCD therapy method affect brain activity. It may help researchers understand why OCD symptoms and brain patterns differ between people and across time.
New York, New YorkAges 18–45 - NCT05558566Recruiting
Neurofeedback training for Tourette-related tics in teens
This study tests whether brain training using “neurofeedback” can reduce Tourette syndrome tics in children ages 10–16. It compares an active neurofeedback condition to a control condition while measuring brain activity with an MRI.
New Haven, ConnecticutAges 10–16 - NCT05609474Recruiting
Talking study of youth addiction services experiences
This study looks at what young people (and their caregivers) experience when they first meet addiction support services, and how they react over time. Sharing your experiences may help improve how these services work for families.
Bron, Auvergne-Rhône-AlpesAges 12–25 - NCT05280028Recruiting
Hormone treatment for overactive bladder and mood symptoms
This trial studies whether hormone treatment can improve overactive bladder symptoms, sexual well-being, mood (depressive symptoms), and body “autonomic” function (automatic body functions like heart rate and sweating) in post-menopausal women. It may help by targeting menopausal changes that can affect these symptoms.
Banqiao District, New TaipeiAges 20 years+ - NCT05405803Recruiting
Web app to improve depressive symptoms in midlife Korean American women
This study tests a web-based (internet) program to help reduce depressive symptoms in midlife Korean American women. You may qualify if you’ve had mild to moderate low mood recently and can use the internet.
Austin, TexasAges 40–60 - NCT05331937RecruitingPhase 3
TMS plus exposure therapy for severe OCD that won’t improve
This trial studies whether TMS (a brain stimulation treatment) can help people with severe OCD who have not responded well to exposure therapy. It combines brain stimulation with intensive exposure therapy to reduce obsessions and compulsions.
Amsterdam, North HollandAges 18 years+ - NCT05599126RecruitingPhase 4
Mianserin plus SSRIs for depression with sleep trouble
This study tests whether adding mianserin to an SSRI (a common antidepressant) can improve depression in people whose main problem also includes sleep trouble. It may help by targeting both mood symptoms and difficulty sleeping.
ShanghaiAges 18–60 - NCT05450354Recruiting
Study of related mental conditions after a child suicide attempt
This study looks at how other mental and emotional problems show up in children after a serious suicide attempt, and compares them with children after a less severe attempt. It aims to better understand what needs support in the hospital and afterward.
ParisAges 9 years+ - NCT05635812Recruiting
Brain and eye tests of facial emotion recognition in autism
This study uses brain and eye measurements to understand how people recognize facial expressions, including in autism and related conditions. It may help researchers find markers that better explain autism-related symptoms and differences in processing emotions.
DijonAges 7–50 - NCT05537610Recruiting
Test a behavior strategy for frequent self-injury
This study looks at how to reduce serious problem behaviors (including self-injury) in children who have it many times per day even after previous treatment. It may help if your child’s behavior is driven by social attention or other positive effects and they can stay on the same supports, school plan, and medicines during the study.
Somerset, New JerseyAges 3–17 - NCT05539534Recruiting
Testing suicide-prevention training for professionals
This trial studies how a suicide-prevention training program for professionals works in real life. If you attend one of the specific trainings listed, your experience may help researchers understand what works to prevent suicide.
GhentAges Any age - NCT05446805Recruiting
Depression study for older people who drive
This study looks at how depression relates to the brain by using blood tests and either a spinal fluid test or brain scans. It may help researchers better understand depression in older drivers and how to measure it.
St Louis, MissouriAges 65 years+ - NCT05394311Recruiting
Sports program to support teens’ mental health in Nepal
This trial tests whether a sports-based program can be realistically used to support mental well-being in adolescents in Nepal. If you join, you’ll help researchers see if the program is practical and helpful for teens.
Biratnagar, KoshiAges 12–19 - NCT05452122Recruiting
Studying how sleep and wakefulness shape memory in epilepsy
This study looks at how your brain makes and keeps memories across waking and sleeping periods. If you have epilepsy and are having depth electrodes placed as part of your care, your team will also use this information to better understand memory and how it may be influenced.
Los Angeles, CaliforniaAges 18–65
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 8,192 recruiting psychiatry studies from the U.S. registry right now, out of 13,292 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Kidney & urinary
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- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.