Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 8,192 recruiting studies in this area right now.
By phase
- Not applicable6,797
- Phase 2511
- Phase 1258
- Phase 3244
- Phase 4213
- Phase 1/Phase 298
- Phase 2/Phase 371
Top conditions
- Depression420
- Anxiety412
- Alzheimer Disease342
- Autism Spectrum Disorder258
- Dementia226
- Mild Cognitive Impairment199
- Schizophrenia192
- Major Depressive Disorder188
- Cognitive Impairment157
- Insomnia152
- Alcohol Use Disorder150
- Opioid Use Disorder145
- Stress136
- PTSD110
- Autism95
- Mental Health92
- Suicidal Ideation92
- Anxiety Disorders85
Leading sponsors
- VA Office of Research and Development104
- Yale University95
- Massachusetts General Hospital78
- Stanford University72
- Assistance Publique - Hôpitaux de Paris65
- Johns Hopkins University63
- University of California, Los Angeles61
- The University of Hong Kong52
- University of Pennsylvania52
- Karolinska Institutet50
Where studies are running
- California529
- New York267
- Massachusetts263
- Texas223
- Maryland176
- Pennsylvania175
- Florida153
- Alabama118
- Arizona117
- Connecticut113
Recruiting studies8,191 total
- NCT06378450Recruiting
Mindfulness meditation: finding the right dose
This study tests how different amounts of mindfulness meditation affect people's mental health. It is for Australian adults who are new to meditation and do not have severe mental or physical health conditions.
Carlton, VictoriaAges 18–65 - NCT06415838Recruiting
Behavioral activation for depression in older adults
This trial tests a simple, practical therapy called behavioral activation to help older adults with depression feel better. It's done in your local community, not in a hospital.
Eskilstuna, SörmlandAges 65 years+ - NCT05621278Recruiting
School study of mental and physical well-being from kids to adults
This study follows students from middle school through high school and asks their parents and teachers questions about mental well-being and physical (body-related) health. It may help researchers understand what supports healthy development over time.
Beijing, Beijing MunicipalityAges 9–65 - NCT05616819Recruiting
Morning light program to improve mood in some service members
This study tests whether getting morning light exposure can improve mood for service members who currently have mild or more depression symptoms. You’d follow a plan for morning light over about 6 weeks, and the researchers check changes in mood.
Tucson, ArizonaAges 18–60 - NCT05636072Recruiting
Online tools to build resilience in adults
This study tests web-based (online) tools designed to help people build resilience. You can take part as a healthcare worker or any adult 18+ who can use the tools and surveys in English.
Durham, North CarolinaAges 18 years+ - NCT05407623Recruiting
Behavior game program for Swedish elementary classrooms
This trial tests whether a structured “good behavior game” helps improve the classroom environment in Swedish elementary schools. It targets regular classes in early grades and is delivered by participating teachers, with the school supporting measurements and parent communication.
StockholmAges 6–10 - NCT05287711Recruiting
Motivational alcohol support to help prevent partner violence
This study tests an extra (adjunct) counseling approach to reduce harmful alcohol use in Veterans enrolled in the Strength at Home program. The goal is to help prevent intimate partner violence (IPV), especially when alcohol is involved.
Boston, MassachusettsAges 18 years+ - NCT05453513Recruiting
Study how depression and cannabis affect the brain in young adults with HIV
This study looks at brain activity to understand how depression and cannabis use may be linked in young adults living with HIV. It mainly involves questionnaires, mental health screening, and brain scans, which may help researchers better understand risk factors and brain “underpinnings.”
Miami, FloridaAges 18–59 - NCT05553197Recruiting
Track mood during therapy using smartphone check-ins
This study looks at how mood changes between therapy sessions by having you answer short mood questions on your smartphone. It may help the researchers understand what support works best for people with mild-to-moderate depression.
Zurich, Canton of ZurichAges 18 years+ - NCT05380765Recruiting
Help for First Nation teens to prevent substance use
This trial tests a positive, prevention-focused approach to help North American Indian (First Nation) teens make healthier choices about substance use. It involves both teens and an adult family member who supports good decision-making.
Kingston, Rhode IslandAges 10–14 - NCT05580614Recruiting
Brain stimulation plus therapy for adults with OCD
This trial tests whether a paired type of at-home/off-site brain stimulation (tVNS) combined with Exposure and Response Prevention (ERP) can reduce OCD symptoms. It may help people with moderate-to-severe OCD who are willing to take part in the treatment and follow study rules.
Gainesville, FloridaAges 18–55 - NCT05368571Recruiting
CHOICES program for teens at risk of pregnancy and STIs
This trial tests a teen-focused program (called CHOICES) to help reduce risky situations that can lead to pregnancy and sexually transmitted infections (STIs). It includes girls ages 14–19 who report recent risk behaviors around sex, condom use, and birth control.
Houston, TexasAges 14–19 - NCT05509998Enrolling by invitation
Improving early care for untreated psychosis
This trial looks at ways to help people get treatment sooner after psychosis starts. It focuses on how screening and better communication across care teams may reduce the time before treatment begins.
New York, New YorkAges 12–30 - NCT05499182Recruiting
Teen depression treatment study for Latino teens
This study is testing a treatment approach for depression in Latino teens, including therapy and/or antidepressant care. It may help by improving how depression is identified and treated for this specific community.
Nashville, TennesseeAges 13 years+ - NCT05436106Recruiting
Reducing stress with a behavioral program for Black gender minority women
This trial tests a behavior-based program meant to help lower stress. It is designed for Black gender minority women who were assigned male at birth.
Atlanta, GeorgiaAges 18–99 - NCT05384808Recruiting
Dog-assisted therapy for motivated kids
This study tests whether therapy sessions that involve a trained therapy dog can improve motivation and engagement in children and teens. It’s for youth who are starting therapy for the first time and can safely and comfortably interact with dogs.
BaselAges 9–17 - NCT05349513Recruiting
Testing a home-care program for schizophrenia-like disorders
This study tests a specific kind of care delivered in a home-like setting for people with schizophrenia or schizoaffective disorder. It may help the care team understand what kinds of supports work best and improve day-to-day treatment.
PoitiersAges 18–65 - NCT05450094Enrolling by invitation
School program to meet children’s mental health needs
This study tests a school-based program designed to better support children’s mental health needs that are currently not being met. It focuses on students and the school team responsible for delivering the support.
Gainesville, FloridaAges 5–105 - NCT05325645RecruitingPhase 3
Weekly brexpiprazole shot for acute schizophrenia flare-ups
This Phase 3 study tests whether a once-weekly brexpiprazole medicine can help people whose schizophrenia is currently flaring up and who need hospital-level care. It compares care for acute relapse using a longer-lasting (weekly) form of brexpiprazole.
Kure-shiAges 18–64 - NCT06569394RecruitingPhase 2
Testing CBD in young adults who use cannabis heavily
This study tests whether cannabidiol (CBD) can help young adults who use cannabis heavily but aren't looking to quit. You'll take a CBD pill and see if it changes your cannabis use or related symptoms.
Aurora, ColoradoAges 18–25 - NCT07199374Recruiting
Testing PARCA digital tool for justice and health
This trial tests a digital tool (called PARCA) that aims to improve fairness and health for people on supervision, like probation. The tool is meant for both officers and the people they supervise who have used drugs.
Austin, TexasAges 18 years+ - NCT05609487Recruiting
Safety plan check to help prevent repeat suicide
This study tests a safety plan after a recent suicide attempt to see if it is safe and helpful at preventing another attempt. You would join a follow-up support program that helps coordinate care and encourages return home, usually within a short emergency visit.
Bron, AURAAges 18–65 - NCT04763343RecruitingPhase 3
Ketamine to help prevent repeat suicide attempts in youth
This Phase 3 study tests ketamine to reduce ongoing suicidal thoughts and help prevent another suicide attempt in youth after a recent attempt. It will compare ketamine treatment against standard care to see if it helps improve safety and reduce suicide risk.
Cleveland, OhioAges 14–30 - NCT04712461Recruiting
Support program to reduce therapist burnout
This trial tests whether adding specific implementation supports can reduce burnout in therapists who provide evidence-based care for children who have experienced trauma. It may help therapists feel more supported while delivering these child trauma treatments.
San Diego, CaliforniaAges 3–99
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 8,192 recruiting psychiatry studies from the U.S. registry right now, out of 13,292 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.