Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,771 recruiting studies in this area right now.
By phase
- Not applicable6,418
- Phase 2494
- Phase 1248
- Phase 3237
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 368
Top conditions
- Anxiety387
- Depression381
- Alzheimer Disease337
- Autism Spectrum Disorder241
- Dementia224
- Mild Cognitive Impairment194
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder142
- Opioid Use Disorder141
- Stress117
- PTSD105
- Mental Health99
- Autism95
- Mild Cognitive Impairment (MCI)88
- Suicidal Ideation87
Leading sponsors
- VA Office of Research and Development105
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University61
- University of California, Los Angeles58
- The University of Hong Kong52
- University of Pennsylvania52
- Karolinska Institutet50
Where studies are running
- California516
- Massachusetts264
- New York255
- Texas209
- Maryland174
- Pennsylvania169
- Florida145
- Alabama118
- Arizona109
- Illinois104
Recruiting studies7,771 total
- NCT07498426RecruitingPhase 3
Study of NIO752 for progressive supranuclear palsy
This trial tests a new medicine called NIO752 for people with progressive supranuclear palsy (PSP), a condition that affects movement, balance, and thinking. The goal is to see if it can help slow the disease's progression.
Scottsdale, ArizonaAges 41–81 - NCT07424404RecruitingPhase 3
Long-term safety study of a medication for psychiatric disorders in children and teens
This study tests a combination medicine (xanomeline and trospium chloride) to see if it is safe and tolerable over a longer period for children and adolescents with psychiatric disorders, especially those with autism-related irritability. It may help families understand if this treatment can be used beyond the initial study period.
Dothan, AlabamaAges 5–17 - NCT07863440Recruiting
Digital therapy for gambling disorder
This trial tests a smartphone-based therapy program to help people stop gambling. It also involves a family member, like a parent, spouse, or sibling, to support the patient during treatment.
Jakarta Pusat, Jakarta Special Capital RegionAges 18 years+ - NCT02568878RecruitingPhase 3
Creatine to help depression and anxiety in meth users
This trial studies whether creatine can reduce depression and anxiety symptoms in people who currently use methamphetamine and also have depression and anxiety. It may help by improving mood and anxiety scores over the course of the study.
Missoula, MontanaAges 18–59 - NCT02889016Recruiting
Markers study for children with PANS and healthy controls
This study looks at physical, immune, and brain-related “markers” in children with PANS and compares them with healthy children. It may help doctors understand what is happening in PANS and how to recognize it more clearly early on.
Palo Alto, CaliforniaAges 4–18 - NCT02951754RecruitingPhase 4
Methylphenidate for adults with ADHD
This trial tests whether methylphenidate (a stimulant medicine) helps adults with attention-deficit/hyperactivity disorder (ADHD). It is checking safety and effectiveness for people who can take the immediate-release form of the medicine.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT03152630Recruiting
Vascular dementia check-up and risk diagnosis study
This study aims to find early ways to diagnose “vascular dementia,” which happens when blood vessel problems affect thinking and memory. It may help by testing how well certain health risk factors and medical information can predict who might be developing it.
TaipeiAges 65 years+ - NCT03222375Recruiting
Home treatment for autism using special sound and imaging devices
This trial studies a home-based treatment for autism (or related conditions) using specially designed sound, image, and electromagnetic devices. It aims to see whether this personalized “treatment code” and device approach can improve autism-related skills and behaviors.
Louisville, KentuckyAges 1 month–21 years - NCT03466619Recruiting
Penile implant surgery for erectile dysfunction when medicines fail
This trial looks at using a penile implant pump to help erections in people whose erectile dysfunction can’t be fixed with standard medicine or can’t safely take it. It may help if pills or other treatments have not worked for you, but it also requires the ability to use the device correctly and safely.
Cairo, ElgharbiaAges 18–80 - NCT01194648Recruiting
HIFU treatment for early prostate cancer
This trial studies a focused ultrasound treatment called HIFU for prostate cancer that appears limited to the early stages. It aims to treat cancer within the prostate while avoiding treatment spread to lymph nodes or distant organs.
London, EnglandAges Up to 90 years - NCT03669315RecruitingPhase 3
Theta burst brain stimulation for gambling disorder
This Phase 3 trial tests whether theta burst stimulation (a type of non-invasive brain treatment) can improve control over gambling urges and behaviors. It is meant for adults with a confirmed diagnosis of gambling disorder and no major complicating mental health or medical issues.
FlorenceAges 18–65 - NCT03830879Recruiting
Pregnancy and child health follow-up study in Shenzhen
This study enrolls pregnant people early in pregnancy and follows their babies’ health through age 7. It may help researchers understand health and development patterns in Shenzhen families and improve future child health care.
Shenzhen, GuangdongAges 15–49 - NCT02037867Recruiting
Study your liver blood markers if you’re at risk
This study looks at how certain blood tests (liver biomarkers) change in people with higher risk for liver disease. It may help doctors understand who is developing liver problems earlier and what patterns in blood tests matter most.
Nottingham, NottsAges 18 years+ - NCT03702907Recruiting
Study of aging and a brain sample bank
This study follows adults as they age and may collect biological samples for future research. It could help researchers understand early and late changes related to aging and brain health.
Washington D.C., District of ColumbiaAges 45 years+ - NCT03495024RecruitingPhase 4
Varenicline for quitting smoking in people with schizophrenia
This trial tests whether varenicline helps people with schizophrenia or schizoaffective disorder stop smoking. It also looks at related nervous-system side effects that can happen with some anti-psychotic medicines.
Philadelphia, PennsylvaniaAges 18–75 - NCT03934957Recruiting
Study of health in people living in Hamburg
This study follows adults living in Hamburg to better understand health and health-related factors over time. You may help researchers learn what influences health in this age group.
HamburgAges 45–74 - NCT03913962Recruiting
Exercise study for children with chronic or autoimmune conditions
This study looks at how physical activity affects muscle, metabolism (how your body uses energy), and body composition in children with certain chronic or autoimmune conditions. It may help doctors understand what types of exercise and monitoring are most beneficial and safe.
Clermont-FerrandAges 6–18 - NCT03846375Recruiting
Therapy trial for self-harm and suicidal thoughts
This study looks at emotional regulation during and alongside standard outpatient dialectical behavior therapy (DBT) for people who have self-harmed or had suicidal thoughts. It may help the team understand which emotions or patterns change with treatment.
BergenAges 18–65 - NCT04216186RecruitingPhase 3
Coenzyme Q for children with ADHD
This trial tests whether taking coenzyme Q can improve symptoms of attention-deficit/hyperactivity disorder (ADHD) in children. It may help if your child has ADHD, but it excludes certain other conditions.
TantaAges 2–18 - NCT04360200Recruiting
Study of thinking changes in older adults
This trial looks at people over age 50 who have mild thinking or memory problems but do not have dementia by standard clinical criteria. It tests how these early changes are characterized and measured using exams such as blood tests and brain scans, which may help improve understanding and future care.
Guangzhou, GuangdongAges 50 years+ - NCT04027244Recruiting
Studying care plans for severe leg blood flow problems
This study looks at how best to manage severe leg ischaemia, a condition where blood flow to the leg is dangerously reduced. It mainly involves patients who are planning an intervention, and some participants may also do special heart imaging tests.
Leicester, LeicestershireAges 18–110 - NCT04017286Recruiting
Pregnancy mental health survey and baby development outcomes study
This study looks at how a pregnant person’s mental well-being during pregnancy relates to their child’s later behavior and development. It mainly involves questionnaires and comparing outcomes, and it may help researchers understand what pregnancy mental health supports best.
Chongqing, Chongqing MunicipalityAges 3 months–6 years - NCT04766177RecruitingPhase 3
Bumetanide for children with autism symptoms
This trial tests whether bumetanide can improve autism symptoms in children. It is for children aged 3 to 12 with autism diagnosed using a standard symptom rating scale.
TantaAges 3–12 - NCT02800395Recruiting
Study links brain changes to diet and blood markers in Alzheimer’s
This study looks at how diet-related and blood “stress” markers relate to how thinking and memory decline over time in people with Alzheimer’s. It may help researchers find useful biomarkers to better track progression and guide future care.
Pierre-BéniteAges 55 years+
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,771 recruiting psychiatry studies from the U.S. registry right now, out of 12,287 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.