Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 8,199 recruiting studies in this area right now.
By phase
- Not applicable6,804
- Phase 2511
- Phase 1256
- Phase 3244
- Phase 4214
- Phase 1/Phase 298
- Phase 2/Phase 372
Top conditions
- Depression419
- Anxiety411
- Alzheimer Disease342
- Autism Spectrum Disorder258
- Dementia227
- Mild Cognitive Impairment201
- Schizophrenia192
- Major Depressive Disorder188
- Cognitive Impairment157
- Insomnia154
- Alcohol Use Disorder150
- Opioid Use Disorder145
- Stress136
- PTSD110
- Autism95
- Mental Health92
- Suicidal Ideation92
- Anxiety Disorders83
Leading sponsors
- VA Office of Research and Development104
- Yale University96
- Massachusetts General Hospital78
- Stanford University72
- Assistance Publique - Hôpitaux de Paris65
- Johns Hopkins University63
- University of California, Los Angeles61
- The University of Hong Kong52
- University of Pennsylvania52
- Karolinska Institutet50
Where studies are running
- California528
- New York267
- Massachusetts261
- Texas224
- Maryland176
- Pennsylvania174
- Florida154
- Alabama118
- Arizona117
- Connecticut114
Recruiting studies8,198 total
- NCT06934954Recruiting
Emotion Skills Program for Early Teens
This program teaches young teens (ages 10-15) and their parents simple skills to handle difficult emotions. It is not for children who are in immediate danger or have severe learning problems.
New York, New YorkAges 10 years+ - NCT06884046Recruiting
Supporting parents of babies with heart conditions
This study offers support to parents whose baby is diagnosed with a heart condition before birth and will need surgery shortly after birth. The goal is to help parents manage stress during this difficult time.
Pessac, FranceAges birth–4 weeks - NCT06013488Recruiting
Character strengths coaching to reduce work stress for health workers
This trial tests a coaching program that uses your personal character strengths to help reduce work stress and improve your wellbeing. It is for rural ASHA health workers in Sehore, Madhya Pradesh who already provide depression care in their communities.
Bhopal, Madhya PradeshAges 18 years+ - NCT05570708Enrolling by invitation
Therapist training trial on how experience shapes therapy
This study looks at how therapists’ personal experience affects their attitude and skills during substance-assisted therapy training. It’s mainly for therapists-in-training, and may help improve how future training and therapy are delivered safely.
BaselAges 27 years+ - NCT07590999Recruiting
Probiotics and Menopause Symptoms: A Research Study
This study tests whether taking a probiotic supplement helps with hot flushes, mood changes, and other symptoms of perimenopause (the years around menopause). Researchers believe gut health may play a role in these symptoms.
Oxford, EnglandAges 45–60 - NCT07627386Recruiting
Lifestyle Program for Older Spouses Caring for Partners
This study tests whether a lifestyle intervention program can help older adults who are caregivers for spouses with memory problems. The program focuses on improving diet, exercise, cognitive activity, and social engagement to support both the caregiver's health and their ability to provide care.
KuopioAges 65 years+ - NCT07124546Recruiting
Acceptance and commitment therapy for cancer distress
This trial tests a type of counseling called acceptance and commitment therapy (ACT) to help people with incurable cancer feel less distressed. It is done in a group over the internet, so you can join from home.
Rochester, MinnesotaAges 18 years+ - NCT06009523Recruiting
Testing brain stimulation for suicidal thoughts
This study tests a non-invasive brain stimulation technique called tDCS, which uses mild electrical currents to reduce suicidal thoughts in people with depression. If you have moderate to severe depression and still have suicidal ideation despite treatment, this might be an option.
Faye-l'AbbesseAges 18 years+ - NCT05587036RecruitingPhase 2/Phase 3
Rifaximin study to see how gut bacteria affect mood
This trial tests whether a gut-targeting antibiotic called rifaximin changes the gut microbiome (gut bacteria) and affects emotion. It is looking for healthy men so any mood or gut changes can be more clearly linked to the study treatment.
LeuvenAges 18–50 - NCT06885606Recruiting
Using brain stimulation to help reduce vaping
This study tests whether a gentle brain stimulation technique called transcranial direct current stimulation (tDCS) can help people who vape daily cut back. You would attend daily sessions for two weeks to see if it makes a difference.
Toronto, OntarioAges 18–65 - NCT05602649RecruitingPhase 1
How cannabis edible type changes drug levels in your body
This Phase 1 study tests how different cannabis edible formulations affect how THC shows up in your blood and how your body responds. It may help researchers choose safer, more predictable edible products based on how people absorb and react to them.
Baltimore, MarylandAges 21–55 - NCT06926153Recruiting
A study to help smokers in psychiatric care reduce smoking
This trial tests a program to help people who smoke and are being treated for psychiatric conditions reduce their smoking. It aims to see if the program works well in real-world psychiatric clinics.
ArmentièresAges 18 years+ - NCT06886204Recruiting
Youth-led research to prevent violence among Black youth
This study partners with Black youth at Boys & Girls Clubs to use participatory research to prevent community violence. Participants will work on projects to identify and address violence in their community.
Atlanta, GeorgiaAges 12–17 - NCT06751784RecruitingPhase 2
Fampridine's effect on memory in mild to moderate depression
This study tests whether the drug fampridine can improve working memory (like short-term memory and focus) in people with mild to moderate depression. The trial is run by the University of Basel and involves multiple visits.
Basel, Canton of Basel-CityAges 18–55 - NCT05678907Recruiting
Test whether a depression questionnaire predicts relapse after discharge
This study checks whether your answers on a depression questionnaire can predict the chance of depression coming back after you leave the hospital. If it works, it may help doctors spot relapse risk earlier and plan follow-up care.
La Roche-BlancheAges 18 years+ - NCT06921226Recruiting
Understanding risk-taking and suicidal behaviors in mental health
This study explores why some people take risks or have suicidal thoughts. It aims to understand these behaviors better to help improve mental health support.
Chambéry, SavoieAges 12–65 - NCT06919952Recruiting
Workplace wellness study for early childhood educators
This study compares two programs to improve early childhood educators' well-being: one focuses on building resilience at work, and the other on increasing physical activity. If you work in a child care center, you may be able to join.
Chapel Hill, North CarolinaAges 18–99 - NCT06919432Recruiting
tACS brain stimulation for teens with self-harm
This trial tests if a gentle brain stimulation technique called tACS (transcranial alternating current stimulation) can help reduce non-suicidal self-injury (NSSI) in teens. If you are 12-21 and have had at least 5 self-harm episodes in the past year with one in the last month, you may be eligible.
Shanghai, Shanghai MunicipalityAges 12–21 - NCT06709027Enrolling by invitation
Mobile health program for depression in older adults
This study is testing a smartphone-based health program designed for older adults with depression. The program aims to help you manage your mood and track changes in thinking and memory using a mobile app.
Fuzhou, FujianAges 60 years+ - NCT05657067Recruiting
Structured family therapy for teens with mild family problems
This pilot study tests whether a structured, structured family therapy approach is practical and helpful for teens and their families. It is meant for families dealing with mild problems and may offer new ways to work through conflict or stress together.
BussumAges 12–18 - NCT06912243Recruiting
Animation to calm kids before ear tube surgery
This study tests if showing children an educational animation before ear tube surgery can lower their fear and anxiety. It’s a simple, short video that explains what will happen, and the goal is to help your child feel calmer.
Merkez, BartınAges 6–10 - NCT06910267Recruiting
Depression treatment study for older adults in APS
This study tests if a proven depression treatment can help older adults who are involved with Adult Protective Services due to neglect or self-neglect. If you are feeling depressed and have an open APS case, you may qualify.
Houston, TexasAges 65 years+ - NCT06151158Recruiting
Preventing suicide in high-risk youth after a crisis visit
This study tests a program to help teens and young adults who have had thoughts of suicide or made an attempt. The program provides extra support after they leave the hospital or treatment program to help keep them safe.
St. Petersburg, FloridaAges 12–24 - NCT07281989Recruiting
Can sound from a watch reduce stress?
This study tests a wearable device called the WAVwatch that uses sound to help lower stress. You wear the watch and see if it makes you feel calmer.
New York, New YorkAges Any age
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 8,199 recruiting psychiatry studies from the U.S. registry right now, out of 13,332 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.