Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 8,199 recruiting studies in this area right now.
By phase
- Not applicable6,804
- Phase 2511
- Phase 1256
- Phase 3244
- Phase 4214
- Phase 1/Phase 298
- Phase 2/Phase 372
Top conditions
- Depression419
- Anxiety411
- Alzheimer Disease342
- Autism Spectrum Disorder258
- Dementia227
- Mild Cognitive Impairment201
- Schizophrenia192
- Major Depressive Disorder188
- Cognitive Impairment157
- Insomnia154
- Alcohol Use Disorder150
- Opioid Use Disorder145
- Stress136
- PTSD110
- Autism95
- Mental Health92
- Suicidal Ideation92
- Anxiety Disorders83
Leading sponsors
- VA Office of Research and Development104
- Yale University96
- Massachusetts General Hospital78
- Stanford University72
- Assistance Publique - Hôpitaux de Paris65
- Johns Hopkins University63
- University of California, Los Angeles61
- The University of Hong Kong52
- University of Pennsylvania52
- Karolinska Institutet50
Where studies are running
- California528
- New York267
- Massachusetts261
- Texas224
- Maryland176
- Pennsylvania174
- Florida154
- Alabama118
- Arizona117
- Connecticut114
Recruiting studies8,198 total
- NCT06906328Recruiting
ADHD and addiction: can cognitive training help?
This study tests whether adding a cognitive remediation program to methylphenidate (a medication for ADHD) improves treatment response in adults who have both ADHD and a substance use or behavioral addiction. It aims to help patients manage symptoms better over the short and medium term.
Brest, Brittany RegionAges 18–99 - NCT06721494RecruitingPhase 2
A single-dose study of CS-1103 for methamphetamine use
This trial tests a single dose of an investigational drug, CS-1103, to see if it is safe and effective for people who use methamphetamine. It may help understand how the drug affects methamphetamine in the body.
Glendale, CaliforniaAges 18–55 - NCT06905223Recruiting
Synbiotics for adults with mild to moderate depression
This pilot study tests whether taking a combination of probiotics and prebiotics (synbiotics) can improve mood in adults with depressive symptoms. It may be an option if you have mild to moderate depression and are looking for a supplement-based approach.
Hong KongAges 18 years+ - NCT05736471Recruiting
Online survey study of thinking and emotions
This study tests how people’s thinking patterns and feelings change during online tasks and surveys. It may help researchers understand how cognition (thinking) and mood (feelings) are connected.
Minneapolis, MinnesotaAges 18 years+ - NCT06904794Recruiting
Teens and gambling after COVID-19: a digital escape room
This study looks at gambling habits among teens after COVID-19 and tests a digital escape room to help prevent gambling in high school students ages 16 to 18.
Zaragoza, ZaragozaAges 16–18 - NCT06775548Enrolling by invitation
Exercise and vitamins for depression relief
This study tests if combining aerobic and resistance exercises with vitamins D and E can reduce stress and inflammation in people with mild to moderate depression. It may help improve mood and overall well-being.
Karachi, SindhAges 25–35 - NCT07578350Enrolling by invitation
Using realistic training to increase awareness about violence against women
This study tests whether a realistic training exercise (called moulage) helps nursing students learn about and recognize violence against women. The goal is to improve how healthcare providers respond to patients who experience abuse.
Istanbul, MAltepeAges 18–20 - NCT05923801Recruiting
Optimizing ECT treatment for difficult depression
This trial studies better ways to deliver ECT (electroconvulsive therapy) for people with difficult-to-treat depression, including some people with bipolar depression. You may be offered an ECT strategy that’s tailored to your situation, with the goal of improving outcomes and reducing problems.
KortenbergAges 18 years+ - NCT05662280Recruiting
Brain stimulation study for teens with ADHD and memory trouble
This study tests whether changing brain activity can improve working memory in teens who have ADHD and trouble remembering and holding information in mind. You and your parent will answer questionnaires, and brain imaging/brain-stimulation testing (MRI/TMS) may be used, with compensation for each session.
East Providence, Rhode IslandAges 12–18 - NCT06793891Recruiting
Ashwagandha extract for stress relief in women
This trial tests whether an ashwagandha supplement can help reduce high stress levels in women. If you are a woman feeling very stressed and meet the other requirements, this study might offer a natural way to manage stress.
Huntsville, AlabamaAges 30–59 - NCT05862636Recruiting
Testing who benefits most from mindfulness meditation
This study looks at people who take part in a mindfulness program at specific study locations and examines who does best. You might be eligible if you are already joining the mindfulness intervention and can complete study tasks in the required language.
AntwerpAges 18 years+ - NCT06531135Enrolling by invitation
Counseling to help you adjust to breast cancer
This trial tests a counseling program to help people with breast cancer feel more positive and cope better. It's designed for newly diagnosed patients who can read and write Chinese.
TaipeiAges 20–70 - NCT06689072Enrolling by invitation
High-frequency brain stimulation for opioid use disorder
This study tests whether a treatment called repetitive transcranial magnetic stimulation (rTMS) can help people with opioid use disorder. It involves a non-invasive procedure that uses magnetic pulses to stimulate certain parts of the brain.
Asyut, Asyut GovernorateAges 18–45 - NCT06875882Recruiting
Stress study for surgeons and musicians
This study looks at stress in surgeons and musicians using wearable brain sensors, body samples, and questionnaires. It aims to understand how stress affects performance and well-being.
Houston, TexasAges 18 years+ - NCT06891235Recruiting
Testing cannabis use with mouth swabs
This study tests whether mouth swabs can detect recent cannabis use. If you use cannabis at least once a week and are between 18 and 30, you may be able to join.
Boston, MassachusettsAges 18–30 - NCT06691022Enrolling by invitation
Smoking, stress, and behavior in children with disabilities
This study looks at how secondhand smoke and parent stress might affect challenging behaviors in children with mental disabilities. It uses a urine test to measure smoke exposure.
Tokat ProvinceAges 4–10 - NCT06874595Recruiting
Exercise and brain stimulation study for healthy adults
This study looks at how a gentle electrical current applied to the head (called brain stimulation) combined with exercise affects your body and mood. It may help researchers understand how these two treatments work together to improve brain health.
Richmond, VirginiaAges 18–50 - NCT06878092Recruiting
A support program for young refugees with emotional distress
This trial tests a program called Problem Management Plus with Emotional Processing (PM+EP) for youth who were forced to leave their home country. It aims to reduce stress and improve daily functioning. If you are a young refugee between 16 and 25 years old and feel very anxious or down, this might help you learn ways to cope.
StockholmAges 16–25 - NCT06876129RecruitingPhase 1
Adding D-serine to TMS for depression
This trial tests whether adding a medication called D-serine to a brain stimulation treatment (TMS) helps improve depression. It’s for adults with major depression who are already getting TMS therapy.
Belmont, MassachusettsAges 18–80 - NCT06869590Recruiting
Study of antibodies in anorexia with liver damage
This study looks for certain antibodies in the blood of people with anorexia nervosa who also have liver problems. It aims to understand if these antibodies contribute to liver damage, which may help find new ways to treat or prevent this complication.
MarseilleAges 6–65 - NCT06864715Recruiting
Preventing depression after a stroke with behavioral activation
This study tests if a talking therapy called behavioral activation can prevent depression in older adults who have had a stroke and have low income. It is for people who are not already severely depressed and live at home.
Houston, TexasAges 55 years+ - NCT07269964Recruiting
At-home brain stimulation for depression maintenance
This trial tests if a gentle, at-home brain stimulation treatment (tDCS) can help prevent depression from returning after successful initial treatment with esketamine, rTMS, or ECT. It is for people who are stable but want to stay well.
München, BavariaAges 18 years+ - NCT06838689Recruiting
Comparing ways to involve people in pediatric, cancer, and serious illness research
This study compares two different methods for including patients, families, and clinicians in qualitative research about pediatric mental health, cancer screening, or serious illness. You can help by sharing your experiences and perspectives.
Hanover, New HampshireAges 18 years+ - NCT05672914Recruiting
Help quitting smoking after a psychiatric hospital stay
This study tests a program meant to help people stop smoking after they leave a psychiatric hospital. It may help you stay smoke-free longer by offering structured support during a high-risk time.
Austin, TexasAges 18 years+
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 8,199 recruiting psychiatry studies from the U.S. registry right now, out of 13,332 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.