Clinical trials
Glioblastoma - Category clinical trials
Below are recruiting glioblastoma - category clinical trials, each written for real people, not researchers. We’re tracking 357 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07410676RecruitingPhase 1/Phase 2
Donor NK cells with IL-15 and pembrolizumab for advanced solid tumors
This trial tests a new type of cell therapy (natural killer cells) made from a donor, combined with low-dose IL-15 (a protein that helps these cells work) and sometimes with pembrolizumab (Keytruda), for people with advanced solid tumors that have not responded to standard treatments. The goal is to see if this combination can shrink tumors or slow their growth.
Beijing, Beijing MunicipalityAges Any age - NCT07411690Recruiting
Spinal fluid leak after brain tumor surgery
This trial checks for spinal fluid leaks after surgery to remove brain tumors. If you are having a planned first-time surgery for a tumor in the upper part of the brain, you may be eligible.
WarsawAges 18 years+ - NCT07413796Recruiting
Comparing skin closure methods in brain tumor surgery
This study compares two ways to close the skin after brain tumor surgery: a continuous stitch under the skin versus separate stitches through the skin. The goal is to see which method leads to better healing and appearance.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT07426848Recruiting
Occupational therapy group for brain tumor patients
This study tests a group-based occupational therapy program to help people with primary brain tumors who are undergoing chemotherapy or other anti-cancer treatments. The goal is to improve daily activities and quality of life.
Dublin, BeaumontAges 18 years+ - NCT07459101Recruiting
MR-guided radiation therapy for high-grade brain tumors
This study tests a new way to deliver radiation therapy for a type of aggressive brain tumor called glioblastoma or grade 4 astrocytoma. Patients get MRI scans during each treatment so the radiation beam can be adjusted precisely, aiming to improve outcomes.
Toronto, OntarioAges 18 years+ - NCT07461948RecruitingPhase 3
Advanced imaging study for glioblastoma patients
This trial uses special MRI scans and a contrast agent to look at the immune environment of glioblastoma tumors. It may help doctors learn more about how the tumor responds to treatment.
Los Angeles, CaliforniaAges 18 years+ - NCT07464925RecruitingPhase 1
Testing GLIX1 for adults with returning high-grade glioma
This trial tests a new drug called GLIX1 to find a safe dose for people whose high-grade glioma (a fast-growing brain tumor) has come back or is getting worse after earlier treatments. It may be an option if you've had no more than two prior treatments.
Tampa, FloridaAges 18 years+ - NCT07468136RecruitingPhase 1/Phase 2
Retifanlimab with or without DFMO for progressive high-grade gliomas
This study tests a combination of two drugs—retifanlimab (an immunotherapy that helps your immune system fight cancer) and DFMO (a medicine that may stop tumor growth)—in people with high-grade brain tumors that are growing. Participants will receive these treatments before and after their planned surgery.
Rochester, MinnesotaAges 18 years+ - NCT07476794RecruitingPhase 2
Daily temozolomide for elderly patients with newly diagnosed brain cancer
This trial tests a daily chemo drug (temozolomide) in patients aged 65 or older with a specific type of aggressive brain cancer that has a certain genetic marker. It aims to see if this daily schedule works well after initial radiation and chemo.
Toronto, OntarioAges 65 years+ - NCT07480941RecruitingPhase 1
CAR-NK cell therapy for recurrent glioblastoma
This trial tests a new treatment using engineered immune cells (CAR-NK cells) that target two markers found on glioblastoma tumors. The treatment is given directly into the brain to fight tumors that have come back after standard therapy.
Shenzhen, GuangdongAges 18–75 - NCT07485049RecruitingEarly Phase 1
BGB-58067 for newly diagnosed glioblastoma with MTAP deletion
This early-stage trial tests an experimental drug (BGB-58067) for people with a newly diagnosed glioblastoma that has a specific gene deletion (MTAP). It aims to see if the drug can shrink the tumor or slow its growth.
Phoenix, ArizonaAges 18 years+ - NCT07284628RecruitingPhase 2
Vortioxetine for newly diagnosed glioblastoma
This trial tests whether the antidepressant vortioxetine can help people with newly diagnosed glioblastoma when added to standard radiation and chemotherapy. The goal is to see if it improves mood, quality of life, and possibly treatment outcomes.
ZurichAges 18 years+ - NCT03510208RecruitingPhase 1/Phase 2
Uses a dye drug during brain or nerve tumor surgery
This trial tests whether a medicine with a fluorescent dye (panitumumab-IRDye800) helps doctors better see certain tumors during surgery. It may help safer, more complete tumor removal for people with glioblastoma or vestibular schwannoma.
Palo Alto, CaliforniaAges 18 years+ - NCT07488754Recruiting
Targeted radiation therapy for new glioma (grade 3-4)
This trial tests a new type of targeted radiation therapy for people with high-grade glioma (grade 3 or 4) that has not progressed after standard treatment. The therapy uses a radioactive substance attached to a protein that targets tumor cells, aiming to deliver radiation directly to the cancer.
Warsaw, PolandAges 18–80 - NCT07511725RecruitingPhase 2
Thiotepa spinal injection to prevent glioblastoma spread
This trial tests whether injecting a chemotherapy drug called thiotepa into the fluid around the brain and spine can prevent glioblastoma from spreading in patients whose tumor touches the fluid-filled spaces or who had a leak during surgery.
Hangzhou, ZhejiangAges 18–75 - NCT07512154Recruiting
Precision Brain Tumor Radiotherapy Using Advanced MRI
This study tests a new way to plan and deliver radiation therapy for glioblastoma (an aggressive brain tumor) using special MRI scans to target cancer cells more precisely. The goal is to improve treatment effectiveness while reducing harm to healthy brain tissue.
Baltimore, MarylandAges 18 years+ - NCT07538128RecruitingEarly Phase 1
New drug YSCH-01 with immunotherapy for recurrent brain cancer
This early-stage trial tests a new drug called YSCH-01, alone or combined with an immunotherapy drug (atezolizumab), for glioblastoma that has come back after previous treatment. The study places a small tube in the brain to deliver the drug directly and monitors safety and how well it works.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07541781RecruitingPhase 1
Sitagliptin for recurrent grade 4 glioma
This trial tests whether the diabetes drug sitagliptin (Januvia) can help slow or shrink a recurrent grade 4 glioma (a type of brain tumor). It's for people whose tumor has come back after standard treatment and who have not used sitagliptin or Avastin before.
Iowa City, IowaAges 18 years+ - NCT07551336RecruitingPhase 1
CAR-NK cells for recurrent glioblastoma and high-grade brain tumors
This trial tests a new type of immune cell therapy called CAR-NK cells to treat glioblastoma or high-grade glioma that has come back or gotten worse after standard treatment. The cells are engineered to recognize and attack tumor cells in the brain.
Shenzhen, GuangdongAges 18–75 - NCT07552233Recruiting
NK Cell Therapy for Recurrent Brain Tumors
This trial tests a new type of immune cell therapy (NK cells) for patients with malignant brain tumors that have come back or worsened despite previous treatment. The goal is to see if these specially prepared immune cells can help fight the cancer.
Beijing, Beijing MunicipalityAges 18–70 - NCT07552467Recruiting
PET Imaging Scan for Detecting Cancer Using New Radioactive Tracer
This study tests a new type of imaging scan (PET/CT or PET/MR) that uses a radioactive tracer to help doctors better detect and diagnose various cancers. The scan targets a specific protein found in tumors, which may help identify cancer more accurately than standard imaging.
Wuhan, HubeiAges 18 years+ - NCT07560865RecruitingPhase 1
New Cell Therapy for Recurring Brain Cancer
This study tests FT536, a new cell-based treatment, for people with a specific type of brain cancer (WHO Grade 4 astrocytoma) that has come back after standard treatment. The trial combines the new therapy with surgery to see if it can help stop the cancer from growing further.
Minneapolis, MinnesotaAges 18–75 - NCT07567196Recruiting
PET imaging to guide surgery for aggressive brain tumors
This trial tests whether using a special PET scan (a type of imaging that shows tumor activity) during brain tumor surgery helps doctors remove more of the tumor safely. You would have a high-grade glioma (an aggressive brain cancer) and be scheduled for surgery.
Torino, TurinAges 18 years+ - NCT07569042RecruitingPhase 1/Phase 2
Continuing NBM-BMX and Temozolomide for Glioblastoma
This is a continuation study for patients who completed or are in the parent trial testing NBM-BMX (an experimental drug) combined with temozolomide (a standard brain-tumor chemotherapy) for newly diagnosed glioblastoma. If you tolerated the earlier treatment well and your doctor believes you could benefit, you may continue the same drugs in this rollover study.
Kaohsiung CityAges 18 years+
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Common questions
- Are there clinical trials for glioblastoma - category?
- Yes. Clin2 currently lists 357 recruiting glioblastoma - category studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a glioblastoma - category trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a glioblastoma - category trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.