Clinical trials
Heart failure clinical trials
A condition where the heart can’t pump blood as well as it should. We’re tracking 949 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06427343RecruitingPhase 4
IV iron: low dose vs high dose for heart failure with low iron
This study compares two different doses of IV iron (low vs high) to see which works better for people with heart failure and low iron levels. It may help you feel less tired and breathe easier.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07382284Recruiting
Long-term survival after LVAD for end-stage heart failure
This trial looks at how well people with advanced heart failure do over the long term after getting a left-ventricular assist device (LVAD). Researchers will check blood and heart tissue samples to learn more about recovery and outcomes.
Nanjing, JiangsuAges Any age - NCT07372651Enrolling by invitation
AI screening for heart failure in pacemaker patients
This trial uses artificial intelligence to screen pacemaker patients for early signs of heart failure. It is designed for people who have a standard pacemaker, do not already have heart failure, and have a high amount of right ventricular pacing.
LeedsAges 18 years+ - NCT07349797Recruiting
Transdermal GFR system to check kidney function in heart failure
This trial tests a sensor placed on the skin to measure kidney function in adults with heart failure. It may help understand how well the kidneys are working without repeated blood draws.
New York, New YorkAges 18 years+ - NCT07337577Recruiting
Heart failure study using AI messages to improve treatment
This study tests whether messages from a large language model (a type of AI) can help doctors prescribe the right medicines for heart failure. It may help people with heart failure get the best guideline-recommended treatments.
Boston, MassachusettsAges 18–85 - NCT07278583Recruiting
Heart failure telemonitoring program evaluation
This trial looks at how well a telemonitoring program works for people with heart failure. It checks if the eligibility rules used by the French health authority make sense.
Clermont-FerrandAges 18 years+ - NCT07259512RecruitingPhase 4
Ramipril once or twice a day for kidney and heart health
This trial tests whether taking ramipril once or twice daily better protects kidney function in people with both chronic kidney disease (stages 3-5, not on dialysis) and heart failure with low pumping strength. It aims to find the best dosing schedule to help both organs.
Kartasura, Central JavaAges 18 years+ - NCT07220798Recruiting
A program to support caregivers of people with heart failure and memory problems
This study tests a program to help caregivers of people with heart failure and memory problems take better care of themselves, so they can feel better and support their loved one more effectively.
New York, New YorkAges 18–101 - NCT07064525Enrolling by invitationPhase 2
Testing a new drug for high blood pressure
This trial tests a new medicine called SPC1001 Low to see if it can safely lower blood pressure in people with essential hypertension (high blood pressure with no known cause). If you are between 19 and 75 years old and have mild to moderate high blood pressure, this study might be an option.
SeoulAges 19–75 - NCT07029906Recruiting
Testing if beta-blocker side effects are due to expectations
This study tests whether some side effects from beta-blockers are caused by your expectations (the nocebo effect) rather than the drug itself. If you have heart failure and stopped a beta-blocker due to symptoms, this study may help understand your experience and potentially find better ways to manage it.
LondonAges 18 years+ - NCT06991257RecruitingPhase 2
Study of PF-07328948 for adults with heart failure
This trial tests a new medicine, PF-07328948, for adults with heart failure to see if it can improve symptoms and daily life. It is for people who have had heart failure for at least 3 months and can walk without too much difficulty.
Beverly Hills, CaliforniaAges 18–79 - NCT06992089Recruiting
Pacemaker study for heart failure with low heart rate
This trial tests a special pacemaker setting to help your heart beat faster during exercise. It may improve your ability to be active if you have heart failure with preserved ejection fraction (HFpEF) and a low resting heart rate.
ValenciaAges 18 years+ - NCT06578078RecruitingPhase 3
Best heart failure care for older patients with kidney disease
This study tests the best way to manage heart failure in older adults who also have kidney problems and high potassium levels. It compares different treatment strategies to see which one is safest and most effective.
Alcorcón, MadridAges 70 years+ - NCT06306573Enrolling by invitation
CardioMEMS heart pressure monitor study in Medicare patients
This study looks at how well the CardioMEMS heart pressure monitor works for people with heart failure who are on Medicare. It gathers real-world information to see if the sensor helps improve health outcomes.
Atlanta, GeorgiaAges 18 years+ - NCT05955456Recruiting
Check ways to spot early heart failure
This study looks for people who may be developing heart failure early, using heart imaging and related checks. If you fit the risk pattern, the results may help find heart failure sooner in similar people.
Manchester, Greater ManchesterAges 50 years+ - NCT06228209Recruiting
Palliative care for advanced heart failure or cancer
This study tests whether adding a palliative care specialist to your regular care team can improve your quality of life if you have advanced heart failure or advanced lung or certain gastrointestinal cancers. It is for people who have been in the hospital recently and live in Manhattan.
New York, New YorkAges 18 years+ - NCT06061627Recruiting
LOT-CRT vs standard CRT for heart failure with NICD
This study compares a newer pacing therapy (LOT-CRT) to standard cardiac resynchronization therapy (BiVP) for people with heart failure who have a specific type of electrical delay in the heart (NICD). The goal is to see if the newer method works better.
Nanjing, JiangsuAges 18–80 - NCT06024746RecruitingPhase 3
Finerenone plus SGLT2i for hospitalized heart failure
This trial tests whether adding two heart medicines together (finerenone and an SGLT2 inhibitor) helps people who are in the hospital for heart failure recover better. It may be an option for you if you are currently hospitalized and your heart stress markers are high.
Fairhope, AlabamaAges 18 years+ - NCT05562167RecruitingPhase 2
Inorganic nitrate plus exercise for heart failure performance
This Phase 2 study tests whether taking inorganic nitrate can improve exercise ability and heart-function symptoms in people with heart failure with reduced pumping. It also checks whether the treatment is safe when combined with an exercise program.
St Louis, MissouriAges 19–79 - NCT04196842Recruiting
Heart failure precision medicine study using heart tests and blood tests
This study looks at how “personalized” (precision) treatment planning for heart failure may work, using results from heart imaging (echocardiogram) or a blood test called B-type natriuretic peptide. You may join if you have heart failure and can follow frequent study check-ins.
Sacramento, CaliforniaAges 21 years+ - NCT07016815Recruiting
Remote monitoring to adjust heart failure medications
This trial tests whether checking in remotely (telemonitoring) helps doctors adjust heart failure medications more effectively. It is for people newly diagnosed with heart failure who have reduced pumping strength and signs of fluid buildup.
Hong Kong, Hong KongAges 19 years+ - NCT06935370RecruitingPhase 3
Testing vicadrostat with empagliflozin for heart failure with weak pump
This trial tests a new drug called vicadrostat combined with another drug, empagliflozin, for people with heart failure and a weak heart pump. It aims to see if this combination helps improve symptoms and outcomes.
Beverly Hills, CaliforniaAges 18 years+ - NCT04848844Recruiting
Congenital heart disease transplant registry study for adults
This study collects and shares anonymous information about adults being considered for a heart transplant because of a congenital (from birth) heart problem or an inherited heart muscle condition. The goal is to better understand these patients and support research that may improve care.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT07029230Recruiting
Blood test during heart surgery to predict heart failure in kids
This study looks at a substance called sST2 in the blood of children having heart surgery. The goal is to see if sST2 levels can help doctors predict heart failure after surgery.
Zurich, Canton of ZurichAges Up to 18 years
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Common questions
- Are there clinical trials for heart failure?
- Yes. Clin2 currently lists 949 recruiting heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.