Clinical trials
Overweight or Obese clinical trials
Below are recruiting overweight or obese clinical trials, each written for real people, not researchers. We’re tracking 1,472 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07581431RecruitingPhase 1
Testing ISM8969 in healthy and obese adults with heart disease risk
This early-stage trial tests a new drug called ISM8969 to see if it's safe and how the body handles it. Participants are either healthy adults or adults who are overweight with risk factors for heart disease, like high blood pressure or high cholesterol.
Melbourne, VictoriaAges 18–80 - NCT07585487Recruiting
How medications work in children of different weights during surgery
This study measures how two common medications—paracetamol (pain reliever) and cefazolin (antibiotic)—move through the body differently in children who are normal weight versus overweight. Researchers will take small blood samples during routine surgery to understand the best doses for each child.
GhentAges 2–15 - NCT05859022Recruiting
Bariatric treatment methods compared for diabetes and metabolism
This trial compares a less invasive heart/artery-based bariatric treatment (bariatric arterial embolization) with standard weight-loss surgery to see how they affect metabolism and type 2 diabetes. You might be considered if you have obesity with type 2 diabetes and have not had prior bariatric surgery.
LisbonAges 18–75 - NCT07568938Recruiting
Anesthesia types and stress response in weight-loss surgery
This study compares two anesthesia methods—inhaled gas (desflurane) versus IV medication (TIVA)—during weight-loss surgery to see how each affects your body's stress response and recovery. The goal is to understand which approach may be safer and more comfortable for patients having bariatric surgery.
AthensAges 18–65 - NCT03441451Recruiting
Bariatric Surgery Registry for people with high BMI
This registry collects information from people who have a higher body weight (BMI over 30). It may help researchers better understand bariatric surgery and outcomes for future care.
Melbourne, VictoriaAges 2–95 - NCT07565051Recruiting
Predicting weight loss after gastric bypass surgery
This study looks at whether measuring muscle mass before gastric bypass surgery can predict how much weight you'll lose afterward. Understanding this connection may help doctors better prepare patients for surgery and set realistic goals.
Geneva, Canton of GenevaAges Any age - NCT07553936Recruiting
Alternative Proteins in Mediterranean Food Supply Chains
This study tests new plant-based and alternative protein foods (like those from legumes, insects, and algae) to see if they're safe, healthy, and practical for everyday use. You'll help researchers understand how these sustainable protein options can work in Mediterranean diets.
Bologna, BOAges 18–65 - NCT07551960Enrolling by invitation
Testing a Health Risk Prevention Platform for Adults
This study tests a digital platform called STELA that helps adults reduce their risk of heart disease and stroke by identifying and managing modifiable health factors like diet, exercise, and stress. You'll complete health assessments online to see if this preventive approach works.
Třinec, Moravian-Silesian RegionAges 18–80 - NCT07543666Recruiting
Exercise and inflammation markers in healthy young adults
This study looks at how starting a structured exercise program affects inflammation in the body. Researchers want to understand the link between physical activity and inflammation markers in healthy young adults.
München, BavariaAges 18–45 - NCT05775497Recruiting
Online weight-loss program for sexual minority women
This study tests an online weight-loss program, with added culturally tailored parts, for sexual minority women who want to lose weight. It may help by coaching healthier habits through email and internet tools.
Providence, Rhode IslandAges 18–70 - NCT07527195RecruitingPhase 1
Study of CagriSema on Muscle Health in Adults with Obesity
This study tests a new medication called CagriSema to understand how it affects muscle health while helping people lose weight. You'll be in the trial for about a year, and researchers will monitor your muscle function and body composition.
Aarhus NAges 50–70 - NCT07528963Enrolling by invitation
Enhanced Cancer Survivorship Care in Rural Kansas Clinics
This study tests a new model of cancer care designed for rural areas, focusing on helping breast, prostate, lung, and colorectal cancer survivors manage their health after treatment. The study works through primary care clinics to make survivorship care more accessible and effective.
Kansas City, KansasAges 18–75 - NCT07530718Recruiting
How Weight-Loss Surgery Affects Body Composition in MS Patients
This study follows people with multiple sclerosis (MS) who are having weight-loss surgery to understand how their body composition—the balance of muscle, fat, and bone—changes after surgery. The research may help doctors better support MS patients through weight-loss surgery.
Baton Rouge, LouisianaAges 18 years+ - NCT07517042Recruiting
Lifestyle changes and mazdutide injection for weight loss
This trial tests whether combining lifestyle changes (diet and exercise) with a medication called mazdutide can help adults with obesity lose weight and keep it off. Mazdutide is an injectable medication that may help reduce appetite and support weight management over 2 years.
Chongqing, Chongqing MunicipalityAges 18 years+ - NCT06756789Recruiting
Comparing standard vs. tailored limb lengths in gastric bypass
This study compares two different ways of measuring the length of the small intestine during a type of weight loss surgery called gastric bypass. If you are eligible, you may help determine which approach leads to better weight loss results.
Coimbatore, Tamil NaduAges 18–65 - NCT06761040Recruiting
Hip and foot strength training for overweight women
This study tests whether adding hip-strengthening exercises to foot-strengthening exercises helps overweight women with flat feet. If you have foot pronation and are in your early 30s, you may be able to join.
Lahore, Punjab ProvinceAges 30–35 - NCT01477957Recruiting
Bariatric surgery and changes in insulin and body energy use
This study tests whether weight-loss surgery improves how your body uses insulin and energy. It compares insulin sensitivity and related measurements before and after surgery to understand who benefits.
Düsseldorf, North Rhine-WestphaliaAges 20–70 - NCT04013282Recruiting
Tests gut and nerve function in people with digestive symptoms
This study maps how the nerves that control digestion and other body functions are working in people with symptoms that may come from nerve-related gut problems. It may help researchers better understand these conditions and improve future treatment.
Louisville, KentuckyAges 10–80 - NCT07481630RecruitingPhase 3
Testing a new medicine for weight loss and knee pain
This study tests if a new medicine called NNC0487-0111 can help people with extra weight and knee osteoarthritis lose weight and reduce knee pain. If you have knee pain most days and are willing to stop pain relievers for short periods, you may be able to join.
Phoenix, ArizonaAges 18 years+ - NCT07487090RecruitingPhase 2
Exercise before or after eating
This study compares exercising on an empty stomach versus after eating to see how it affects energy use. It may help you understand when to exercise for better weight management.
Fort Smith, ArkansasAges 18–59 - NCT06780813Recruiting
High flow oxygen to reduce infections in obese gynecologic cancer patients
This trial tests whether giving high flow oxygen during and after surgery can lower the risk of infections in obese women with gynecological cancer. It may help improve recovery after surgery.
AthensAges 18–85 - NCT07480109Recruiting
More protein while on weight-loss meds in women
This study tests if eating extra protein helps middle-aged women with overweight or obesity who are just starting a GLP-1 medication. You would eat extra protein for a few weeks while staying active as usual.
Austin, TexasAges 30–60 - NCT07478861Enrolling by invitation
Vibration training for seniors with knee arthritis and obesity
This study tests whether whole-body vibration training can help older adults who have both severe knee arthritis and obesity. It aims to improve strength, mobility, and quality of life.
Banī SuwayfAges 60–75 - NCT07479498Recruiting
Family weight health program for children 5–12
This trial tests a family-based program to help children ages 5 to 12 who are above a healthy weight. It focuses on increasing physical activity and healthy habits, and includes text messages from your clinic.
Salt Lake City, UtahAges Any age
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Common questions
- Are there clinical trials for overweight or obese?
- Yes. Clin2 currently lists 1,472 recruiting overweight or obese studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obese trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obese trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.