Clinical trials
Right Heart Failure clinical trials
Below are recruiting right heart failure clinical trials, each written for real people, not researchers. We’re tracking 131 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06125925Recruiting
Ablation for AFib in patients with heart failure and preserved ejection fraction
This study tests whether a catheter ablation procedure can help people with atrial fibrillation and a kind of heart failure where the heart pumps normally but doesn't relax properly (HFpEF). It looks at whether the procedure can improve symptoms and heart function.
NanjingAges 18–80 - NCT07858799Recruiting
Study of a new device for heart failure with reduced pumping ability
This trial tests a new device that creates a small shunt (passage) in the heart to help relieve pressure and improve symptoms in people with heart failure and a weak heart pump. The goal is to see if the device is safe and helpful for patients like you.
Cologne, GermanyAges 18 years+ - NCT03523416Recruiting
Shunt device for heart failure with reduced pumping function
This trial studies a small device placed in the heart to create a passage that may help relieve pressure and improve symptoms in people with heart failure and a weak pumping function. It aims to see if the device is safe and helpful for daily life.
La Jolla, CaliforniaAges 18 years+ - NCT07709208Recruiting
Mitral valve repair for leak that worsens with exercise
This trial tests a procedure to fix a leaky mitral valve that only becomes severe during exercise. It may help people with symptoms like shortness of breath or fatigue who haven't responded to standard heart medications.
DüsseldorfAges 18 years+ - NCT05327062Recruiting
Noninvasive mapping to guide a heart resynchronization device
This trial tests a noninvasive way to map your heart’s wiring and veins to help guide placement of a heart resynchronization therapy (CRT) device. If you have certain abnormal heart rhythm and weak heart pumping, it may help doctors place the therapy more accurately and safely.
Chicago, IllinoisAges 18 years+ - NCT07666698RecruitingPhase 1/Phase 2
Metformin to improve heart function after LVAD implant
This trial tests if metformin, a medicine commonly used for diabetes, can help improve heart function in people who have a mechanical heart pump (LVAD). You may be able to join if you are between 18 and 75, have a continuous-flow LVAD, and have a condition called insulin resistance (where your body doesn't use insulin well) but your blood sugar levels are well-controlled.
Nanjing, JiangsuAges 18–75 - NCT05760924Recruiting
Testing a new heart pacing method for CRT nonresponders
This trial tests whether a different pacing approach called left bundle branch pacing can improve outcomes and heart structure changes in people who did not improve with standard biventricular CRT. It may help some patients with ongoing heart failure symptoms and weak heart pumping.
TomskAges 18–80 - NCT05428631Recruiting
Monitoring device tested in severe kidney and heart failure
This study checks how safe a small heart-pressure monitoring device is for people with advanced heart failure and severe kidney problems. It looks at whether doctors can continuously track heart filling/pressure to help manage symptoms and reduce risks.
Nîmes, GardAges 18–85 - NCT07489547RecruitingPhase 2/Phase 3
Can stable heart failure patients stop some medications?
This trial is testing whether people whose heart failure has improved (with better pumping strength) can safely stop taking some of their heart medications. It is for stable patients who have had significant improvement in their heart function from a low point.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT07400042Recruiting
Peripheral vein pressure test for heart failure patients
This study tests if measuring pressure from a vein in the arm can help guide treatment for people hospitalized with worsening heart failure. It aims to understand if this simple procedure could replace or reduce the need for more invasive monitoring.
Milwaukee, WisconsinAges 18 years+ - NCT07293923Recruiting
Magenta Elevate™ study for cardiogenic shock
This trial tests a new heart pump called the Magenta Elevate™ to help people whose heart suddenly stops pumping enough blood (cardiogenic shock). It aims to improve blood flow and reduce strain on the heart.
TbilisiAges 40–89 - NCT07270536Recruiting
Pacing and heart pressure in HFpEF exercise
This study tests whether a special pacing setting during exercise can help improve heart filling pressures in people with heart failure with preserved ejection fraction (HFpEF) who already have a DDD pacemaker. If you have HFpEF and a pacemaker, you may help researchers find better ways to manage your condition during activity.
HasseltAges 18 years+ - NCT07206602Recruiting
AI-guided left bundle branch pacing
This trial tests a new way to place a pacemaker lead in the heart's left bundle branch area, guided by artificial intelligence. It aims to improve heart function in people with heart failure who need pacing.
Rochester, MinnesotaAges 18 years+ - NCT03954574Recruiting
Check blood flow changes in lungs during exercise testing
This study measures how blood moves through your lungs and heart while you exercise, using standard heart-lung pressure measurements. It may help doctors better understand unexplained breathing trouble or suspected pulmonary hypertension and improve how testing and care are guided.
Phoenix, ArizonaAges 18 years+ - NCT07096544Recruiting
Using a lung artery sensor to guide LVAD care
This study tests whether a small sensor (CardioMEMS) implanted in the lung artery can help doctors better manage LVAD settings and reduce hospital visits. It is for people who already have a HeartMate 3 heart pump and are stable enough to go home.
Plano, TexasAges 21–85 - NCT07087613Recruiting
Detecting heart and lung pressure problems with a smart stethoscope
This study tests if a digital stethoscope and a simple 3-lead ECG (heart rhythm test) can detect two heart conditions: high blood pressure in the lungs (pulmonary hypertension) and low pumping strength of the heart (low ejection fraction). It's intended for adults who recently had a heart ultrasound or a heart catheterization.
O'Fallon, IllinoisAges 18 years+ - NCT03994874RecruitingPhase 1/Phase 2
Testing fluid removal through the belly in heart-kidney failure
This trial studies a treatment that removes extra fluid through a catheter placed in the abdomen (peritoneal ultrafiltration) for people with “cardio-renal syndrome” (heart and kidney problems together). It may help those who stay congested despite high-dose water pills (diuretics) and have certain heart circulation and fluid signs.
ChietiAges 18 years+ - NCT06812533Recruiting
Testing a new approach for heart failure with weak pump
This study tests a new device or procedure to help people with heart failure and a weak heart pump. If you have a low ejection fraction and are on standard medications, you may be able to join.
Los Angeles, CaliforniaAges 18 years+ - NCT06495970Recruiting
Pulmonary artery denervation for heart failure with lung hypertension
This trial tests a procedure called pulmonary artery denervation (PADN) for people with heart failure and a certain type of high blood pressure in the lungs (pulmonary hypertension Group 2). The goal is to see if using a special device called the Gradient Denervation System can help control the high pressures and improve your symptoms.
BadalonaAges 22–85 - NCT06414265Recruiting
Testing a new valve for severe mitral regurgitation
This trial tests a new device called the SATURN system, which places a new mitral valve without open-heart surgery. It is for people aged 65 and older with severe mitral regurgitation who are at high risk for surgery.
TbilisiAges 65 years+ - NCT04555161Recruiting
Test of an implanted device for pulmonary arterial hypertension
This trial studies an implanted system (the Aria CV Pulmonary Hypertension System) to treat pulmonary arterial hypertension, a serious lung-blood vessel and heart condition. It aims to see whether the device can improve outcomes for people who are still sick despite existing PH medicines.
La Jolla, CaliforniaAges 18 years+ - NCT06241430Recruiting
CardioClip study: testing a new valve repair for leaky heart valve
This study tests a new clip procedure (CardioClip) to repair a leaky mitral valve in people with heart failure. It aims to see if the clip can improve symptoms and heart function.
New York, New YorkAges 18–90 - NCT06220396Recruiting
Heart and Metabolism in Healthy Adults (CAMERA Study)
This study looks at how the heart and metabolism work together during exercise in healthy adults. It uses special tests (including a heart catheterization during exercise and an MRI) to understand normal heart function and reserve capacity.
Rochester, MinnesotaAges 30 years+ - NCT06195059Recruiting
Heart ultrasound with contrast during exercise to study lungs
This study uses a special ultrasound (echocardiography) with a contrast dye to see how blood flows through your lungs during exercise. It aims to help doctors better understand why patients get short of breath during activity.
Rochester, MinnesotaAges 18 years+
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Common questions
- Are there clinical trials for right heart failure?
- Yes. Clin2 currently lists 131 recruiting right heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a right heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a right heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.